Age-associated increase of spontaneous mutant frequency and molecular nature of mutation in newborn and old lacZ-transgenic mouse

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 447, Issue 2, 2000, Pages 165-177

  Ono, Tetsuya ^a   Ikehata, Hironobu ^a   Nakamura, Shingo ^a   Saito, Yusuke ^a   Hosoi, Yoshio ^a   Takai, Yoshihiro ^a   Yamada, Shogo ^a   Onodera, Junichi ^b   Yamamoto, Kazuo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Institute for Environmental Science   (Japan)

Author keywords

Aging; DNA sequence; LacZ; Mutation; Transgenic mouse

Indexed keywords

AMINO ACID; DNA;

AGED; AGING; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; MOLECULAR DYNAMICS; MOUSE; MUTATION; MUTATION RATE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

AGING; ANIMALS; ANIMALS, NEWBORN; BASE SEQUENCE; BRAIN; DNA; DNA MUTATIONAL ANALYSIS; FEMALE; LAC OPERON; LIVER; MALE; MICE; MICE, TRANSGENIC; MUTATION; MYOCARDIUM; SKIN; SPLEEN; TESTIS;

ANIMALIA; MUS MUSCULUS;

EID: 0034646079     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(99)00200-6     Document Type: Article

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