Development of macrophages of cyprinid fish

Developmental and Comparative Immunology

Volumn 33, Issue 4, 2009, Pages 411-429

  Hanington, Patrick C ^a   Tam, Jonathan ^a   Katzenback, Barbara A ^a   Hitchen, Steven J ^a   Barreda, Daniel R ^a   Belosevic, Miodrag ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cytokines; Development; Differentiation; Fish; Growth factors; Macrophage; Proliferation; Teleost; Transcription factors; Transplantation

Indexed keywords

COLONY STIMULATING FACTOR 1; DNA BINDING PROTEIN; EARLY GROWTH RESPONSE FACTOR 1; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEUKEMIA INHIBITORY FACTOR; PROGRANULIN; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR NFAT;

ACETYLATION; CELL DIFFERENTIATION; CELL MATURATION; CELL RENEWAL; DNA BINDING; DNA REPLICATION; DNA SEQUENCE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; INNATE IMMUNITY; MACROPHAGE; MACROPHAGE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVIEW; STEM CELL; STEM CELL TRANSPLANTATION; TELEOST; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

CYPRINIDAE; DANIO RERIO; MAMMALIA; OSTEICHTHYES; TELEOSTEI; VERTEBRATA;

EID: 58649099609     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dci.2008.11.004     Document Type: Review

References (390)

1. Ihle J. Pathways in cytokine regulation of hematopoiesis. Annals of the New York Academy of Sciences 938 (2001) 129-130
2. Lotem J., and Sachs L. Cytokine control of developmental programs in normal hematopoiesis and leukemia. Oncogene 21 (2002) 3284-3294
3. Sweet M.J., and Hume D.A. CSF-1 as a regulator of macrophage activation and immune responses. Archivum Immunologiae et Therapiae Experimentalis 51 (2003) 169-177
4. Barreda D.R., Hanington P.C., and Belosevic M. Regulation of myeloid development and function by colony stimulating factors. Developmental and Comparative Immunology 28 (2004) 509-554
5. Spyridonidis A., Mertelsmann R., and Henschler R. Hematopoietic cell proliferation and differentiation. Current Opinion in Hematology 3 (1996) 321-328
6. Zhang Y., Willson T., Metcalf D., Cary D., Hilton D.J., Clark R., et al. The box-1 region of the leukemia inhibitory factor receptor alpha-chain cytoplasmic domain is sufficient for hemopoietic cell proliferation and differentiation. Journal of Biological Chemistry 273 (1998) 34370-34383
7. Parravicini E., van de Ven C., Anderson L., and Cairo M.S. Myeloid hematopoietic growth factors and their role in prevention and/or treatment of neonatal sepsis. Transfusion Medicine Reviews 16 (2002) 11-24
8. Nandi S., Akhter M.P., Seifert M.F., Dai X.M., and Stanley E.R. Developmental and functional significance of the CSF-1 proteoglycan chondroitin sulfate chain. Blood 107 (2006) 786-795
9. Stull D.M. Colony-stimulating factors: beyond the effects on hematopoiesis. American Journal of Health-System Pharmacy 59 (2002) S12-20
10. Motoyoshi K. Biological activities and clinical application of M-CSF. International Journal of Hematology 67 (1998) 109-122
11. Barreda D.R., and Belosevic M. Transcriptional regulation of hemopoiesis. Developmental and Comparative Immunology 25 (2001) 763-789
12. Spooncer E., Brouard N., Nilsson S.K., Williams B., Liu M.C., Unwin R.D., et al. Developmental fate determination and marker discovery in hematopoietic stem cell biology using proteomic fingerprinting. Molecular and Cellular Proteomics 7 (2008) 573-581
13. Kastner P., and Chan S. PU.1: a crucial and versatile player in hematopoiesis and leukemia. The International Journal of Biochemistry & Cell Biology 40 (2008) 22-27
14. Jude C.D., Gaudet J., Speck N., and Ernst P. Leukemia and hematopoietic stem cells: balancing proliferation and quiescence. Cell Cycle 7 (2008)
15. Bonifer C., and Hume D.A. The transcriptional regulation of the colony-stimulating factor 1 receptor (csf1r) gene during hematopoiesis. Frontiers in Bioscience 13 (2008) 549-560
16. Stanley E.R., Berg K.L., Einstein D.B., Lee P.S., and Yeung Y.G. The biology and action of colony stimulating factor-1. Stem Cells 12 Suppl 1 (1994) 15-24 [discussion 5]
17. Di Croce L. Chromatin modifying activity of leukaemia associated fusion proteins. Human Molecular Genetics 14 1 (2005) R77-R84
18. Ng S.Y., Yoshida T., and Georgopoulos K. Ikaros and chromatin regulation in early hematopoiesis. Current Opinion in Immunology 19 (2007) 116-122
19. Johnson B.S., Mueller L., Si J., and Collins S.J. The cytokines IL-3 and GM-CSF regulate the transcriptional activity of retinoic acid receptors in different in vitro models of myeloid differentiation. Blood 99 (2002) 746-753
20. Bottardi S., Ghiam A.F., Bergeron F., and Milot E. Lineage-specific transcription factors in multipotent hematopoietic progenitors: a little bit goes a long way. Cell Cycle 6 (2007) 1035-1039
21. Hume D.A., Allan W., Fabrus B., Weidemann M.J., Hapel A.J., and Bartelmez S. Regulation of proliferation of bone marrow-derived macrophages. Lymphokine Research 6 (1987) 127-139
22. Flajnik M.F. The immune system of ectothermic vertebrates. Veterinary Immunology and Immunopathology 54 (1996) 145-150
23. Bayne C.J. Pronephric leucocytes of Cyprinus carpio: isolation, separation and characterization. Veterinary Immunology and Immunopathology 12 (1986) 141-151
24. Neumann N.F., Barreda D., and Belosevic M. Production of a macrophage growth factor(s) by a goldfish macrophage cell line and macrophages derived from goldfish kidney leukocytes. Developmental and Comparative Immunology 22 (1998) 417-432
25. Plytycz B., Flory C.M., Galvan I., and Bayne C.J. Leukocytes of rainbow trout (Oncorhynchus mykiss) pronephros: cell types producing superoxide anion. Developmental and Comparative Immunology 13 (1989) 217-224
26. van Loon J.J., Secombes C.J., Egberts E., and van Muiswinkel W.B. Ontogeny of the immune system in fish-role of the thymus. Advances in Experimental Medicine and Biology 149 (1982) 335-341
27. Zelikoff J.T., Enane N.A., Bowser D., Squibb K.S., and Frenkel K. Development of fish peritoneal macrophages as a model for higher vertebrates in immunotoxicological studies. I: Characterization of trout macrophage morphological, functional, and biochemical properties. Fundamental and Applied Toxicology 16 (1991) 576-589
28. Traver D., Herbomel P., Patton E.E., Murphey R.D., Yoder J.A., Litman G.W., et al. The zebrafish as a model organism to study development of the immune system. Advances in Immunology 81 (2003) 253-330
29. Trede N.S., Langenau D.M., Traver D., Look A.T., and Zon L.I. The use of zebrafish to understand immunity. Immunity 20 (2004) 367-379
30. Bertrand J.Y., Kim A.D., Violette E.P., Stachura D.L., Cisson J.L., and Traver D. Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development 134 (2007) 4147-4156
31. Su F., Juarez M.A., Cooke C.L., Lapointe L., Shavit J.A., Yamaoka J.S., et al. Differential Regulation of Primitive Myelopoiesis in the Zebrafish by Spi-1/Pu.1 and C/ebp1. Zebrafish 4 (2007) 187-199
32. Yokomizo T., Hasegawa K., Ishitobi H., Osato M., Ema M., Ito Y., et al. Runx1 is involved in primitive erythropoiesis in the mouse. Blood. 111 (2008) 4075-4080
33. Davidson A.J., and Zon L.I. The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene 23 (2004) 7233-7246
34. de Jong J.L., and Zon L.I. Use of the zebrafish system to study primitive and definitive hematopoiesis. Annual Review of Genetics 39 (2005) 481-501
35. Hogan B.M., Layton J.E., Pyati U.J., Nutt S.L., Hayman J.W., Varma S., et al. Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish. Current Biology 16 (2006) 506-511
36. Qian F., Zhen F., Xu J., Huang M., Li W., and Wen Z. Distinct functions for different scl isoforms in Zebrafish primitive and definitive hematopoiesis. PLoS Biology 5 (2007) e132
37. Jin H., Xu J., and Wen Z. Migratory path of definitive hematopoietic stem/progenitor cells during zebrafish development. Blood 109 (2007) 5208-5214
38. Yamaguchi M., and Wakahara M. Contribution of ventral and dorsal mesoderm to primitive and definitive erythropoiesis in the salamander Hynobius retardatus. Developmental Biology 230 (2001) 204-216
39. Nakanishi T., and Ototake M. The graft-versus-host reaction (GVHR) in the ginbuna crucian carp, Carassius auratus langsdorfii. Developmental and Comparative Immunology 23 (1999) 15-26
40. Kobayashi I., Moritomo T., Ototake M., and Nakanishi T. Isolation of side population cells from ginbuna carp (Carassius auratus langsdorfii) kidney hematopoietic tissues. Developmental and Comparative Immunology 31 (2007) 696-707
41. Kobayashi I., Sekiya M., Moritomo T., Ototake M., and Nakanishi T. Demonstration of hematopoietic stem cells in ginbuna carp (Carassius auratus langsdorfii) kidney. Developmental and Comparative Immunology 30 (2006) 1034-1046
42. Moritomo T., Asakura N., Sekiya M., Ototake M., Inoue Y., and Nakanishi T. Cell culture of clonal ginbuna crucian carp hematopoietic cells: differentiation of cultured cells into erythrocytes in vivo. Developmental and Comparative Immunology 28 (2004) 863-869
43. Neumann N.F., Barreda D.R., and Belosevic M. Generation and functional analysis of distinct macrophage sub-populations from goldfish (Carassius auratus L.) kidney leukocyte cultures. Fish and Shellfish Immunology 10 (2000) 1-20
44. Barreda D.R., and Belosevic M. Characterisation of growth enhancing factor production in different phases of in vitro fish macrophage development. Fish and Shellfish Immunology 11 (2001) 169-185
45. Barreda D.R., Hanington P.C., Walsh C.K., Wong P., and Belosevic M. Differentially expressed genes that encode potential markers of goldfish macrophage development in vitro. Developmental and Comparative Immunology 28 (2004) 727-746
46. Hanington P.C., Barreda D.R., and Belosevic M. A novel hematopoietic granulin induces proliferation of goldfish (Carassius auratus L.) macrophages. Journal of Biological Chemistry 281 (2006) 9963-9970
47. Hanington P.C., and Belosevic M. Characterization of the leukemia inhibitory factor receptor in the goldfish (Carassius auratus). Fish and Shellfish Immunology 18 (2005) 359-369
48. Hanington P.C., and Belosevic M. Interleukin-6 family cytokine M17 induces differentiation and nitric oxide response of goldfish (Carassius auratus L.) macrophages. Developmental and Comparative Immunology 31 (2007) 817-829
49. Barreda D.R., Hanington P.C., Stafford J.L., and Belosevic M. A novel soluble form of the CSF-1 receptor inhibits proliferation of self-renewing macrophages of goldfish (Carassius auratus L.). Developmental and Comparative Immunology 29 (2005) 879-894
50. Hanington P.C., Wang T., Secombes C.J., and Belosevic M. Growth factors of lower vertebrates: characterization of goldfish (Carassius auratus L.) macrophage colony-stimulating factor-1. Journal of Biological Chemistry 282 (2007) 31865-31872
51. Haddad G., Hanington P.C., Wilson E.C., Grayfer L., and Belosevic M. Molecular and functional characterization of goldfish (Carassius auratus L.) transforming growth factor beta. Developmental and Comparative Immunology 32 (2008) 654-663
52. Belosevic M., Hanington P.C., and Barreda D.R. Development of goldfish macrophages in vitro. Fish and Shellfish Immunology 20 (2006) 152-171
53. Roberts R., Gallagher J., Spooncer E., Alien T.D., Bloomfield F., and Dexter T.M. Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis. Nature 332 (1988) 376-378
54. Watt F.M. Out of Eden: stem cells and their niches. Science 287 (2000) 1427
55. Trentin J.J. Influence of hematopoietic organ stroma (hematopoietic inductive microenvironments) on stem cell differentiation. Regulation of Hematopoiesis 1 (1970) 616-623
56. Metcalf D. Hematopoietic regulators: redundancy or subtlety?. Blood 82 (1993) 3515-3523
57. Van Zant G., and Goldwasser E. Competition between erythropoietin and colony-stimulating factor for target cells in mouse marrow. Blood 53 (1979) 946-965
58. Ogawa M. Stochastic model revisited. The International Journal of Hematology 69 (1999) 2-5
59. Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood 81 (1993) 2844-2853
60. Fairbairn L.J., Cowling G.J., Reipert B.M., and Dexter T.M. Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74 (1993) 823-832
61. Till J.E., McCulloch E.A., and Siminovitch L. A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells. Proceedings of the National Academy of Sciences 51 (1964) 29-36
62. Humphries R.K., Eaves A.C., and Eaves C.J. Self-renewal of hemopoietic stem cells during mixed colony formation in vitro. Proceedings of the National Academy of Sciences 78 (1981) 3629-3633
63. Nakahata T., Gross A.J., and Ogawa M. A stochastic model of self-renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture. Journal of Cellular Physiology 113 (1982) 455-458
64. Reddy E.P., Korapati A., Chaturvedi P., and Rane S. IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled. Oncogene 19 (2000) 2532-2547
65. Tenen D.G., Hromas R., Licht J.D., and Zhang D.E. Transcription factors, normal myeloid development, and leukemia. Blood 90 (1997) 489-519
66. Lenny N., Westendorf J.J., and Hiebert S.W. Transcriptional regulation during myelopoiesis. Molecular Biology Reports 24 (1997) 157-168
67. Zhang P., Zhang X., Iwama A., Yu C., Smith K.A., Mueller B.U., et al. PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood 96 (2000) 2641-2648
68. Ness S.A., and Engel J.D. Vintage reds and whites: combinatorial transcription factor utilization in hematopoietic differentiation. Current Opinion in Genetics & Development 4 (1994) 718-724
69. Metcalf D. Cellular hematopoiesis in the twentieth century. Seminars in Hematology 36 (1999) 5-12
70. van Oostveen J., Bijl J., Raaphorst F., Walboomers J., and Meijer C. The role of homeobox genes in normal hematopoiesis and hematological malignancies. Leukemia 13 (1999) 1675-1690
71. Orkin S.H., and Zon L.I. Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132 (2008) 631-644
72. Sieweke M.H., and Graf T. A transcription factor party during blood cell differentiation. Current Opinion in Genetics & Development 8 (1998) 545-551
73. Goetz T.L., Gu T.L., Speck N.A., and Graves B.J. Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha 2. Molecular Cell Biology 20 (2000) 81
74. Gu T.L., Goetz T.L., Graves B.J., and Speck N.A. Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha 2 (AML1). Molecular Cell Biology 20 (2000) 91
75. Woo A.J., Moran T.B., Schindler Y., Choe S.K., Langer N.B., Sullivan M.R., et al. Identification of ZBP-89 as a novel GATA-1 associated transcription factor involved in megakaryocytic and erythroid development. Molecular Cell Biology 28 (2008) 2675-2689
76. Thomas T., Corcoran L.M., Gugasyan R., Dixon M.P., Brodnicki T., Nutt S.L., et al. Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells. Genes & Development 20 (2006) 1175-1186
77. Levanon D., Goldstein R.E., Bernstein Y., Tang H., Goldenberg D., Stifani S., et al. Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors. Proceedings of the National Academy of Sciences 95 (1998) 11590
78. Holmes M., Turner J., Fox A., Chisholm O., Crossley M., and Chong B. hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates gata-mediated activation. Journal of Biological Chemistry 274 (1999) 23491-23498
79. Xu L., Glass C.K., and Rosenfeld M.G. Coactivator and corepressor complexes in nuclear receptor function. Current Opinion in Genetics & Development 9 (1999) 140-147
80. Burke L., and Baniahmad A. Co-repressors 2000. The FASEB Journal 14 (2000) 1876
81. Gewirtz A.M., and Calabretta B. A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science 242 (1988) 1303-1306
82. Anfossi G., Gewirtz A.M., and Calabretta B. An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines. Proceedings of the National Academy of Sciences 86 (1989) 3379
83. Lord K.A., Abdollahi A., Hoffman-Liebermann B., and Liebermann D.A. Proto-oncogenes of the fos/jun family of transcription factors are positive regulators of myeloid differentiation. Molecular Cell Biology 13 (1993) 841
84. Tsai S., and Collins S.J. A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage. Proceedings of the National Academy of Sciences of United States of America 90 (1993) 7153-7157
85. Kelly L.M., Englmeier U., Lafon I., Sieweke M.H., and Graf T. MafB is an inducer of monocytic differentiation. EMBO Journal 19 (2000) 1987-1997
86. Johnson B.S., Chandraratna R.A.S., Heyman R.A., Allegretto E.A., Mueller L.M., and Collins S.J. Retinoid × Receptor (RXR) agonist-induced activation of dominant-negative RXR-retinoic acid receptor alpha 403 heterodimers is developmentally regulated during myeloid differentiation. Molecular Cell Biology 19 (1999) 3372
87. Bavisotto L. Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro. The Journal of Experimental Medicine 174 (1991) 1097-1101
88. Liebermann D.A., and Hoffman B. Differentiation primary response genes and proto-oncogenes as positive and negative regulators of terminal hematopoietic cell differentiation. Stem Cells 12 (1994) 352
89. Nguyen H.Q., Hoffman-Liebermann B., and Liebermann D.A. The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage. Cell 72 (1993) 197-209
90. Wu J., Zhu J.Q., Zhu D.X., Scharfman A., Lamblin G., and Han K.K. Selective inhibition of normal murine myelopoiesis "in vitro" by a Hox 2.3 antisense oligodeoxynucleotide. Cell and Molecular Biology 38 (1992) 367-376
91. Lill M.C., Fuller J.F., Herzig R., Crooks G.M., and Gasson J.C. The role of the homeobox gene, HOX B7, in human myelomonocytic differentiation. Blood 85 (1995) 692-697
92. Tsai S., Bartelmez S., Heyman R., Damm K., Evans R., and Collins S.J. A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line. Genes and Development 6 (1992) 2258
93. Shen W.F., Detmer K., Mathews C.H., Hack F.M., Morgan D.A., Largman C., et al. Modulation of homeobox gene expression alters the phenotype of human hematopoietic cell lines. EMBO Journal 11 (1992) 983
94. Chevalier S., Fourcin M., Robledo O., Wijdenes J., Pouplard-Barthelaix A., and Gascan H. Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein. Journal of Biological Chemistry 65 (2005) 1129-1135
95. Leonard W.J. Type 1 cytokines and interferons and their receptors. In: Paul W.E. (Ed). Fundamental immunology. 5th ed. (2003), Lippincott Williams & Wilkins, Philadelphia
96. Rosenbauer F., and Tenen D.G. Transcription factors in myeloid development: balancing differentiation with transformation. Nature Reviews Immunology 7 (2007) 105-117
97. Min I.M., Pietramaggiori G., Kim F.S., Passegué E., Stevenson K.E., and Wagers A.J. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells. Cell 2 (2008) 380-391
98. Lee S.L., Wang Y., and Milbrandt J. Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transplantation factor NGFI-A (EGR1). Molecular Cell Biology 16 (1996) 4566-4572
99. Laslo P., Spooner C.J., Warmflash A., Lancki D.W., Lee H.J., Sciammas R., et al. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell 126 (2006) 755-766
100. Hock H., Hamblen M.J., Rooke H.M., Traver D., Bronson R.T., Cameron S., et al. Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity 18 (2003) 109-120
101. Muzzey D., and van Oudenaarden A. When it comes to decisions, myeloid progenitors crave positive feedback. Cell 126 (2006) 650-652
102. Fujiwara Y., Chang A.N., Williams A.M., and Orkin S.H. Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood 103 (2004) 583-585
103. Fujiwara Y., Browne C.P., Cunniff K., Goff S.C., and Orkin S.H. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proceedings of the National Academy of Sciences 93 (1996) 12355
104. Weiss M.J., Keller G., and Orkin S.H. Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells. Genes and Development 8 (1994) 1184
105. Migliaccio A.R., Rana R.A., Sanchez M., Lorenzini R., Centurione L., Bianchi L., et al. GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1 low mouse mutant. The Journal of Experimental Medicine 197 (2003) 281-296
106. Shivdasani R.A., Fujiwara Y., McDevitt M.A., and Orkin S.H. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO Journal 16 (1997) 3965-3973
107. Yu C., Cantor A.B., Yang H., Browne C., Wells R.A., Fujiwara Y., et al. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. The Journal of Experimental Medicine 195 (2002) 1387-1395
108. Kobayashi M., and Yamamoto M. Regulation of GATA1 gene expression. The Journal of Biochemistry 142 (2007) 1
109. Tsai F.Y., and Orkin S.H. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 89 (1997) 3636-3643
110. Tsai F.Y., Keller G., Kuo F.C., Weiss M., Chen J., Rosenblatt M., et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371 (1994) 221-226
111. Kulessa H., Frampton J., and Graf T. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes and Development 9 (1995) 1250
112. Ward A.C., Loeb D.M., Soede-Bobok A.A., Touw I.P., and Friedman A.D. Regulation of granulopoiesis by transcription factors and cytokine signals. Leukemia 14 (2000) 973-990
113. Magli M.C., Largman C., and Lawrence H.J. Effects of HOX homeobox genes in blood cell differentiation. Journal of Cell Physiology 173 (1997) 168-177
114. Bijl J., Thompson A., Ramirez-Solis R., Krosl J., Grier D.G., Lawrence H.J., et al. Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. Blood 108 (2006) 116
115. Azcoitia V., Aracil M., Martínez A.C., and Torres M. The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo. Developmental Biology 280 (2005) 307-320
116. Saldi T., Wilusz C., MacMorris M., and Blumenthal T. Functional redundancy of worm spliceosomal proteins U1A and U2B. Proceedings of the National Academy of Sciences 104 (2007) 9753
117. de Bruijn M., and Speck N.A. Core-binding factors in hematopoiesis and immune function. Oncogene 23 (2004) 4238-4248
118. Kim W.Y., Sieweke M., Ogawa E., Wee H.J., Englmeier U., Graf T., et al. Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains. EMBO Journal 18 (1999) 1609-1620
119. Giese K., Kingsley C., Kirshner J.R., and Grosschedl R. Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes and Development 9 (1995) 995
120. Sun W., Graves B.J., and Speck N.A. Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins. Journal of Virology 69 (1995) 4941
121. Nagulapalli S., Pongubala J.M.R., and Atchison M.L. Multiple proteins physically interact with PU.1: transcriptional synergy with NF-IL6β (C/EBPδ, CRP3). Journal of Immunology 155 (1995) 4330-4338
122. Oelgeschläger M., Nuchprayoon I., Lüscher B., and Friedman A.D. C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter. Molecular Cell Biology 16 (1996) 4717
123. Pongubala J.M.R., and Atchison M.L. PU.1 can participate in an active enhancer complex without its transcriptional activation domain. Proceedings of the National Academy of Sciences 94 (1997) 127
124. Bassuk A.G., and Leiden J.M. A direct physical association between ETS and AP-1 transcription factors in normal human T cells. Immunity 3 (1995) 223-237
125. Behre G., Whitmarsh A.J., Coghlan M.P., Hoang T., Carpenter C.L., Zhang D.E., et al. c-Jun Is a JNK-independent coactivator of the PU.1 transcription factor. Journal of Biological Chemistry 274 (1999) 4939-4946
126. Erman B., and Sen R. Context dependent transactivation domains activate the immunoglobulin mu heavy chain gene enhancer. EMBO Journal 15 (1996) 4665-4675
127. Hernandez-Munain C., and Krangel M.S. c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer. Molecular Cell Biology 15 (1995) 3090
128. Hernandez-Munain C., and Krangel M.S. Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. Molecular Cell Biology 14 (1994) 473
129. Britos-Bray M., and Friedman A.D. Core binding factor cannot synergistically activate the myeloperoxidase proximal enhancer in immature myeloid cells without c-Myb. Molecular Cell Biology 17 (1997) 5127-5135
130. Petrovick M.S., Hiebert S.W., Friedman A.D., Hetherington C.J., Tenen D.G., and Zhang D.E. Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1. Molecular Cell Biology 18 (1998) 3915
131. Libermann T.A., Pan Z., Akbarali Y., Hetherington C.J., Boltax J., Yergeau D.A., et al. AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter. Journal of Biological Chemistry 274 (1999) 24671-24676
132. Bruhn L., Munnerlyn A., and Grosschedl R. ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function. Genes and Development 11 (1997) 640
133. Westendorf J.J., Yamamoto C.M., Lenny N., Downing J.R., Selsted M.E., and Hiebert S.W. The t (8; 21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation. Molecular Cell Biology 18 (1998) 322
134. Zhang D.E., Hetherington C.J., Meyers S., Rhoades K.L., Larson C.J., Chen H.M., et al. CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter. Molecular Cell Biology 16 (1996) 1231
135. Selvamurugan N., Chou W.Y., Pearman A.T., Pulumati M.R., and Partridge N.C. Parathyroid hormone regulates the rat collagenase-3 promoter in osteoblastic cells through the cooperative interaction of the activator protein-1 site and the runt domain binding sequence. Journal of Biological Chemistry 273 (1998) 10647-10657
136. Cho J.Y., Akbarali Y., Zerbini L.F., Gu X., Boltax J., Wang Y., et al. Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene. Journal of Biological Chemistry 279 (2004) 19512
137. Ferreira R., Ohneda K., Yamamoto M., and Philipsen S. GATA1 function, a paradigm for transcription factors in hematopoiesis. Molecular Cell Biology 25 (2005) 1215
138. Tsang A.P., Fujiwara Y., Hom D.B., and Orkin S.H. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes and Development 12 (1998) 1176
139. Morceau F., Schnekenburger M., Dicato M., and Diederich M. GATA-1: friends, brothers, and coworkers. Annals of the New York Academy of Sciences 1030 (2004) 537-554
140. Crispino J.D., Lodish M.B., MacKay J.P., and Orkin S.H. Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation the GATA-1: FOG complex. Molecular Cell 3 (1999) 219-228
141. Eisbacher M., Holmes M.L., Newton A., Hogg P.J., Khachigian L.M., Crossley M., et al. Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding. Molecular Cell Biology 23 (2003) 3427
142. Gregory R.C., Taxman D.J., Seshasayee D., Kensinger M.H., Bieker J.J., and Wojchowski D.M. Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters. Blood 87 (1996) 1793
143. Merika M., and Orkin S.H. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Kruppel family proteins Sp1 and EKLF. Molecular Cell Biology 15 (1995) 2437-2447
144. Woo A.J., Moran T.B., Schindler Y.L., Choe S.-K., Langer N.B., Sullivan M.R., et al. Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development. Molecular Cell Biology 28 (2008) 2675-2689
145. Woo A., Moran T.B., Choe S.-K., Schindler Y., Sullivan M., Fujiwara Y., et al. Identification of Zfp148 (ZBP-89) as a novel GATA-1 associated Kruppel-type zinc finger transcription factor required for megakaryopoiesis and definitive erythropoiesis. Blood Cells, Molecules, and Diseases 38 (2007) 129-130
146. Kehrl J.H. Hematopoietic lineage commitment: role of transcription factors. Stem Cells 13 (1995) 223
147. Bockamp E.O., McLaughlin F., Murrell A., and Green A.R. Transcription factors and the regulation of haemopoiesis: lessons from GATA and SCL proteins. Bioessays 16 (1994) 481-488
148. Cross M.A., Heyworth C.M., Murrell A.M., Bockamp E.O., Dexter T.M., and Green A.R. Expression of lineage restricted transcription factors precedes lineage specific differentiation in a multipotent haemopoietic progenitor cell line. Oncogene 9 (1994) 3013-3016
149. Yamaguchi Y., Nishio H., Kasahara T., Ackerman S.J., Koyanagi H., and Suda T. Models of lineage switching in hematopoietic development: a new myeloid-committed eosinophil cell line(YJ) demonstrates trilineage potential. Leukemia 12 (1998) 1430-1439
150. Zhang P., Behre G., Pan J., Iwama A., Wara-aswapati N., Radomska H.S., et al. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proceedings of the National Academy of Sciences 96 (1999) 8705
151. Nutt S.L., Heavey B., Rolink A.G., and Busslinger M. Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature 401 (1999) 556-562
152. Shapiro L.H., and Look A.T. Transcriptional regulation in myeloid cell differentiation. Current Opinion in Hematology 2 (1995) 3-11
153. Rekhtman N., Radparvar F., Evans T., and Skoultchi A.I. Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells. Genes and Development 13 (1999) 1398-1411
154. Visvader J.E., Elefanty A.G., Strasser A., and Adams J.M. GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line. EMBO Journal 11 (1992) 4557
155. Visvader J.E., Crossley M., Hill J., Orkin S.H., and Adams J.M. The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line. Molecular Cell Biology 15 (1995) 634
156. Yamada T., Kondoh N., Matsumoto M., Yoshida M., Maekawa A., and Oikawa T. Overexpression of PU.1 induces growth and differentiation inhibition and apoptotic cell death in murine erythroleukemia cells. Blood 89 (1997) 1383
157. Martin D.I., and Orkin S.H. Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1. Genes and Development 4 (1990) 1886
158. Tsang A.P., Visvader J.E., Turner C.A., Fujiwara Y., Yu C., Weiss M.J., et al. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell 90 (1997) 109-119
159. Bellon T., Perrotti D., and Calabretta B. Granulocytic differentiation of normal hematopoietic precursor cells induced by transcription factor PU.1 correlates with negative regulation of the c-myb promoter. Blood 90 (1997) 1828-1839
160. DeKoter R.P., and Singh H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 288 (2000) 1439
161. McNagny K.M., Sieweke M.H., Döderlein G., Graf T., and Nerlov C. Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1. EMBO Journal 17 (1998) 3669
162. Emambokus N., Vegiopoulos A., Harman B., Jenkinson E., Anderson G., and Frampton J. Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. EMBO Journal 22 (2003) 4478-4488
163. Lécuyer E., and Hoang T. SCL: From the origin of hematopoiesis to stem cells and leukemia. Experimental Hematology 32 (2004) 11-24
164. Robb L., Elwood N.J., Elefanty A.G., Kontgen F., Li R., Barnett L.D., et al. The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse. EMBO Journal 15 (1996) 4123-4129
165. Porcher C., Swat W., Rockwell K., Fujiwara Y., Alt F.W., and Orkin S.H. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell 86 (1996) 47-57
166. Aplan P.D., Nakahara K., Orkin S.H., and Kirsch I.R. The SCL gene product: a positive regulator of erythroid differentiation. EMBO Journal 11 (1992) 4073-4081
167. Hoang T., Paradis E., Brady G., Billia F., Nakahara K., Iscove N.N., et al. Opposing effects of the basic helix-loop-helix transcription factor SCL on erythroid and monocytic differentiation. Blood 87 (1996) 102-111
168. Hall M.A., Curtis D.J., Metcalf D., Elefanty A.G., Sourris K., Robb L., et al. The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12. Proceedings of the National Academy of Sciences 100 (2003) 992
169. Mikkola H.K., Klintman J., Yang H., Hock H., Schlaeger T.M., Fujiwara Y., et al. Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature 421 (2003) 547-551
170. Marziali G., Perrotti E., Ilari R., Coccia E.M., Mantovani R., Testa U., et al. The activity of the CCAAT-box binding factor NF-Y is modulated through the regulated expression of its A subunit during monocyte to macrophage differentiation: regulation of tissue-specific genes through a ubiquitous transcription factor. Blood 93 (1999) 519-526
171. Steinman R.A. mRNA stability control: a clandestine force in normal and malignant hematopoiesis. Leukemia 21 (2007) 1158-1171
172. Meijlink F., Curran T., Miller A.D., and Verma I.M. Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene. Proceedings of the National Academy of Sciences 82 (1985) 4987-4991
173. Zhang G., and Ghosh S. Toll-like receptor-mediated NF-κB activation: A phylogenetically conserved paradigm in innate immunity. The Journal of Clinical Investigation 107 (2001) 13-19
174. Ammon C., Mondal K., Andreesen R., and Krause S.W. Differential expression of the transcription factor NF-κB during human mononuclear phagocyte differentiation to macrophages and dendritic cells. Biochemical and Biophysical Research Communications 268 (2000) 99-105
175. Baldwin Jr. A.S. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annual Review of Immunology 14 (1996) 649
176. Cartwright P., and Helin K. Nucleocytoplasmic shuttling of transcription factors. Cellular and Molecular Life Sciences (CMLS) 57 (2000) 1193-1206
177. Grossmann M., Nakamura Y., Grumont R., and Gerondakis S. New insights into the roles of ReL/NF-kappaB transcription factors in immune function, hemopoiesis and human disease. The International Journal of Biochemistry and Cell Biology 31 (1999) 1209-1219
178. Han Y., Weinman S., Boldogh I., Walker R.K., and Brasier A.R. Tumor necrosis factor-alpha-inducible IkappaBalpha proteolysis mediated by cytosolic m-calpain. A mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-kappab activation. Journal of Biological Chemistry 274 (1999) 787-794
179. Masuda E.S., Naito Y., Arai K., and Arai N. Expression of lymphokine genes in T cells. The Immunologist 1 (1993) 198
180. Masuda E.S., Imamura R., Amasaki Y., Arai K., and Arai N. Signalling into the T-cell nucleus NFAT regulation. Cellular Signalling 10 (1998) 599-611
181. Rao A. NF-ATp: A transcription factor required for the co-ordinate induction of several cytokine genes. Immunology Today 15 (1994) 274-281
182. Crabtree G.R. Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT. Cell 96 (1999) 611-614
183. Shibasaki F., Price E.R., Milan D., and McKeon F. Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT 4. Nature 382 (1996) 370-373
184. Kuo C.T., and Leiden J.M. Transcriptional regulation of t lymphocyte development and function. Annual Reviews in Immunology 17 (1999) 149-187
185. Desterro J.M.P., Rodriguez M.S., and Hay R.T. Regulation of transcription factors by protein degradation. Cellular and Molecular Life Sciences 57 (2000) 1207-1219
186. Whitmarsh A.J., and Davis R.J. Regulation of transcription factor function by phosphorylation. Cellular and Molecular Life Sciences 57 (2000) 1172-1183
187. Pulverer B.J., Hughes K., Franklin C.C., Kraft A.S., Leevers S.J., and Woodgett J.R. Co-purification of mitogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukaemic cells. Oncogene 8 (1993) 407-415
188. Woodgett J.R., Pulverer B.J., Nikolakaki E., Plyte S., Hughes K., Franklin C.C., et al. Regulation of jun/AP-1 oncoproteins by protein phosphorylation. Advances in Second Messenger and Phosphoprotein Research 28 (1993) 261-269
189. Tachibana M., Tezuka C., Muroi S., Nishimoto S., Katsumoto T., Nakajima A., et al. Phosphorylation of Runx1 at Ser249, Ser266, and Ser276 is dispensable for bone marrow hematopoiesis and thymocyte differentiation. Biochemical and Biophysical Research Communications 368 (2008) 536-542
190. Cowley D.O., and Graves B.J. Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition. Genes and Development 14 (2000) 366
191. Feng D., and Kan Y.W. The binding of the ubiquitous transcription factor Sp1 at the locus control region represses the expression of {beta}-like globin genes. Proceedings of the National Academy of Sciences 102 (2005) 9896
192. Galanis A., Yang S.H., and Sharrocks A.D. Selective targeting of MAPKs to the ETS domain transcription factor SAP-1. Journal of Biological Chemistry 276 (2001) 965-973
193. Fuchs S.Y., Tappin I., and Ronai Z. Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation. Journal of Biological Chemistry 275 (2000) 12560-12564
194. Haidweger E., Novy M., and Rotheneder H. Modulation of Sp1 activity by a cyclin A/CDK complex. Journal of Molecular Biology 306 (2001) 201-212
195. Wick K.L.R., and Berton M.T. IL-4 induces serine phosphorylation of the STAT6 transactivation domain in B lymphocytes. Molecular Immunology 37 (2000) 641-652
196. Yang S.H., Shore P., Willingham N., Lakey J.H., and Sharrocks A.D. The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1. EMBO Journal 18 (1999) 5666-5674
197. Bannister A.J., and Miska E.A. Regulation of gene expression by transcription factor acetylation. Cellular and Molecular Life Sciences 57 (2000) 1184-1192
198. Sharrocks A.D. Introduction: The regulation of eukaryotic transcription factor function. Cellular and Molecular Life Sciences 57 (2000) 1147-1148
199. Hung H.L., Lau J., Kim A.Y., Weiss M.J., and Blobel G.A. CREB-binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites. Molecular Cell Biology 19 (1999) 3496
200. Boyes J., Byfield P., Nakatani Y., and Ogryzko V. Regulation of activity of the transcription factor GATA-1 by acetylation. Nature 396 (1998) 594-598
201. Dubnau J., and Struhl G. RNA recognition and translational regulation by a homeodomain protein. Nature 379 (1996) 694-699
202. Rivera-Pomar R., Niessing D., Schmidt-Ott U., Gehring W.J., and Jackle H. RNA binding and translational suppression by bicoid. Nature 379 (1996) 746-749
203. Collavin L., Gostissa M., Avolio F., Secco P., Ronchi A., Santoro C., et al. Modification of the erythroid transcription factor GATA-1 by SUMO-1. Proceedings of the National Academy of Sciences 101 (2004) 8870
204. Khanna-Gupta A. Sumoylation and the function of CCAAT enhancer binding protein alpha (C/EBP[alpha]). Blood Cells, Molecules, and Diseases 41 (2008) 77-81
205. Koschmieder S., Rosenbauer F., Steidl U., Owens B.M., and Tenen D.G. Role of Transcription Factors C/EBPa and PU.1 in Normal Hematopoiesis and Leukemia. The International Journal of Hematology 81 (2005) 368-377
206. Pabst T., Mueller B.U., Zhang P., Radomska H.S., Narravula S., Schnittger S., et al. Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBP alpha), in acute myeloid leukemia. Nature Genetics 27 (2001) 263-270
207. Preudhomme C., Sagot C., Boissel N., Cayuela J.M., Tigaud I., de Botton S., et al. Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association (ALFA). Blood 100 (2002) 2717-2723
208. Valk P.J.M., Verhaak R.G.W., Beijen M.A., Erpelinck C.A.J., and van Doorn-Khosrovani S.B. Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia. New England Journal of Medicine 350 (2004) 1617
209. Fixe P., and Praloran V. Macrophage colony-stimulating-factor (M-CSF or CSF-1) and its receptor: structure-function relationships. European Cytokine Network 8 (1997) 125-136
210. Stanley E.R., Berg K.L., Einstein D.B., Lee P.S., Pixley F.J., Wang Y., et al. Biology and action of colony-stimulating factor-1. Molecular Reproduction and Development 46 (1997) 4-10
211. Bot F.J., van Eijk L., Broeders L., Aarden L.A., and Lowenberg B. Interleukin-6 synergizes with M-CSF in the formation of macrophage colonies from purified human marrow progenitor cells. Blood 73 (1989) 435-437
212. Bot F.J., van Eijk L., Schipper P., Backx B., and Lowenberg B. Synergistic effects between GM-CSF and G-CSF or M-CSF on highly enriched human marrow progenitor cells. Leukemia 4 (1990) 325-328
213. Praloran V. Structure, biosynthesis and biological roles of monocyte-macrophage colony stimulating factor (CSF-1 or M-CSF). Nouvelle revue francaise d'hematologie 33 (1991) 323-333
214. Bradley T.R., Metcalf D., and Robinson W. Stimulation by leukaemic sera of colony formation in solid agar cultures by proliferation of mouse bone marrow cells. Nature 213 (1967) 926-927
215. Robinson W.A., Stanley E.R., and Metcalf D. Stimulation of bone marrow colony growth in vitro by human urine. Blood 33 (1969) 396-399
216. Stanley E.R., and Guilbert L.J. Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1). Journal of Immunologic Methods 42 (1981) 253-284
217. Das S.K., Stanley E.R., Guilbert L.J., and Forman L.W. Discrimination of a colony stimulating factor subclass by a specific receptor on a macrophage cell line. Journal of Cell Physiology 104 (1980) 359-366
218. Guilbert L., Robertson S.A., and Wegmann T.G. The trophoblast as an integral component of a macrophage-cytokine network. Immunology and Cell Biology 71 Pt 1 (1993) 49-57
219. Hamilton J.A. CSF-1 and cell cycle control in macrophages. Molecular Reproduction and Development 46 (1997) 19-23
220. Horiguchi J., Warren M.K., and Kufe D. Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor. Blood 69 (1987) 1259-1261
221. Oster W., Lindemann A., Horn S., Mertelsmann R., and Herrmann F. Tumor necrosis factor (TNF)-alpha but not TNF-beta induces secretion of colony stimulating factor for macrophages (CSF-1) by human monocytes. Blood 70 (1987) 1700-1703
222. Harrington M., Konicek B.W., Xia X.L., and Song A. Transcriptional regulation of the mouse CSF-1 gene. Molecular Reproduction and Development 46 (1997) 39-44 [discussion 5]
223. Gruber M.F., Williams C.C., and Gerrard T.L. Macrophage-colony-stimulating factor expression by anti-CD45 stimulated human monocytes is transcriptionally up-regulated by IL-1 beta and inhibited by IL-4 and IL-10. Journal of Immunology 152 (1994) 1354-1361
224. Horiguchi J., Warren M.K., Ralph P., and Kufe D. Expression of the macrophage specific colony-stimulating factor (CSF-1) during human monocytic differentiation. Biochemical and Biophysics Research Communication 141 (1986) 924-930
225. Oster W., Lindemann A., Mertelsmann R., and Herrmann F. Regulation of gene expression of M-, G-, GM-, and multi-CSF in normal and malignant hematopoietic cells. Blood Cells 14 (1988) 443-462
226. Ladner M.B., Martin G.A., Noble J.A., Nikoloff D.M., Tal R., Kawasaki E.S., et al. Human CSF-1: gene structure and alternative splicing of mRNA precursors. EMBO Journal 6 (1987) 2693-2698
227. Pixley F.J., and Stanley E.R. CSF-1 regulation of the wandering macrophage: complexity in action. Trends in Cell Biology 14 (2004) 628-638
228. Kawasaki E.S., and Ladner M.B. Molecular biology of macrophage colony-stimulating factor. Immunology Series 49 (1990) 155-176
229. Kawasaki E.S., Ladner M.B., Wang A.M., Van Arsdell J., Warren M.K., Coyne M.Y., et al. Molecular cloning of a complementary DNA encoding human macrophage-specific colony-stimulating factor (CSF-1). Science (New York, NY) 230 (1985) 291-296
230. Chambers S.K., and Kacinski B.M. Messenger RNA decay of macrophage colony-stimulating factor in human ovarian carcinomas in vitro. Journal of the Society for Gynecologic Investigation 1 (1994) 310-316
231. Bakheet T., Frevel M., Williams B.R., Greer W., and Khabar K.S. ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins. Nucleic Acids Research 29 (2001) 246-254
232. Stein J., and Rettenmier C.W. Proteolytic processing of a plasma membrane-bound precursor to human macrophage colony-stimulating factor (CSF-1) is accelerated by phorbol ester. Oncogene 6 (1991) 601-605
233. Stein J., Borzillo G.V., and Rettenmier C.W. Direct stimulation of cells expressing receptors for macrophage colony-stimulating factor (CSF-1) by a plasma membrane-bound precursor of human CSF-1. Blood 76 (1990) 1308-1314
234. Deng P., Wang Y.L., Haga Y., and Pattengale P.K. Multiple factors determine the selection of the ectodomain cleavage site of human cell surface macrophage colony-stimulating factor. Biochemistry 37 (1998) 17898-17904
235. Rettenmier C.W., and Roussel M.F. Differential processing of colony-stimulating factor 1 precursors encoded by two human cDNAs. Molecular Cell Biology 8 (1988) 5026-5034
236. Das S.K., Stanley E.R., Guilbert L.J., and Forman L.W. Human colony-stimulating factor (CSF-1) radioimmunoassay: resolution of three subclasses of human colony-stimulating factors. Blood 58 (1981) 630-641
237. Gilbert H.S., Praloran V., and Stanley E.R. Increased circulating CSF-1 (M-CSF) in myeloproliferative disease: association with myeloid metaplasia and peripheral bone marrow extension. Blood 74 (1989) 1231-1234
238. Hanamura T., Motoyoshi K., Yoshida K., Saito M., Miura Y., Kawashima T., et al. Quantitation and identification of human monocytic colony-stimulating factor in human serum by enzyme-linked immunosorbent assay. Blood 72 (1988) 886-892
239. Shadle P.J., Allen J.I., Geier M.D., and Koths K. Detection of endogenous macrophage colony-stimulating factor (M-CSF) in human blood. Experimental Hematology 17 (1989) 154-159
240. Koths K. Structure-function studies on human macrophage colony-stimulating factor (M-CSF). Molecular Reproduction and Development 46 (1997) 31-37 [discussion 7-8]
241. Jiang X., Zhou A., Cen B., Qiu Q., Dong X., and Xu X. Expression of soluble, active human macrophage colony stimulating factor in Escherichia coli. Biochemistry & Molecular Biology International 42 (1997) 325-328
242. Price L.K., Choi H.U., Rosenberg L., and Stanley E.R. The predominant form of secreted colony stimulating factor-1 is a proteoglycan. Journal of Biological Chemistry 267 (1992) 2190-2199
243. Chitu V., and Stanley E.R. Colony-stimulating factor-1 in immunity and inflammation. Current Opinion in Immunology 18 (2006) 39-48
244. Pierce J.H., Di Marco E., Cox G.W., Lombardi D., Ruggiero M., Varesio L., et al. Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA. Proceedings of the National Academy of Sciences 87 (1990) 5613-5617
245. Munn D.H., and Cheung N.K. Antibody-dependent antitumor cytotoxicity by human monocytes cultured with recombinant macrophage colony-stimulating factor. Induction of efficient antibody-mediated antitumor cytotoxicity not detected by isotope release assays. The Journal of Experimental Medicine 170 (1989) 511-526
246. Munn D.H., and Cheung N.K. Phagocytosis of tumor cells by human monocytes cultured in recombinant macrophage colony-stimulating factor. The Journal of Experimental Medicine 172 (1990) 231-237
247. Munn D.H., and Cheung N.K. Efficient killing of neuroblastoma cells by human monocytes activated with recombinant human macrophage colony-stimulating factor and anti-tumor antibody. Progress in Clinical and Biological Research 366 (1991) 389-394
248. Munn D.H., and Cheung N.K. Antibody-independent phagocytosis of tumor cells by human monocyte-derived macrophages cultured in recombinant macrophage colony-stimulating factor. Cancer Immunology, Immunotherapy 41 (1995) 46-52
249. Karbassi A., Becker J.M., Foster J.S., and Moore R.N. Enhanced killing of Candida albicans by murine macrophages treated with macrophage colony-stimulating factor: evidence for augmented expression of mannose receptors. Journal of Immunology 139 (1987) 417-421
250. Ho J.L., Reed S.G., Wick E.A., and Giordano M. Granulocyte-macrophage and macrophage colony-stimulating factors activate intramacrophage killing of Leishmania mexicana amazonensis. The Journal of Infectious Diseases 162 (1990) 224-230
251. Wing E.J., Ampel N.M., Waheed A., and Shadduck R.K. Macrophage colony-stimulating factor (M-CSF) enhances the capacity of murine macrophages to secrete oxygen reduction products. Journal of Immunology 135 (1985) 2052-2056
252. Begg S.K., Radley J.M., Pollard J.W., Chisholm O.T., Stanley E.R., and Bertoncello I. Delayed hematopoietic development in osteopetrotic (op/op) mice. The Journal of Experimental Medicine 177 (1993) 237-242
253. Wiktor-Jedrzejczak W., Bartocci A., Ferrante Jr. A.W., Ahmed-Ansari A., Sell K.W., Pollard J.W., et al. Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse. Proceedings of the National Academy of Sciences 87 (1990) 4828-4832
254. Abboud S.L., Woodruff K., Liu C., Shen V., and Ghosh-Choudhury N. Rescue of the osteopetrotic defect in op/op mice by osteoblast-specific targeting of soluble colony-stimulating factor-1. Endocrinology 143 (2002) 1942-1949
255. Ryan G.R., Dai X.M., Dominguez M.G., Tong W., Chuan F., Chisholm O., et al. Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis. Blood 98 (2001) 74-84
256. Guilbert L.J., and Stanley E.R. Specific interaction of murine colony-stimulating factor with mononuclear phagocytic cells. The Journal of Cell Biology 85 (1980) 153-159
257. Wang Z., and Melmed S. Identification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative promoter usage. Journal of Biological Chemistry 272 (1997) 27957-27965
258. Sherr C.J., Borzillo G.V., Kato J., Shurtleff S.A., Downing J.R., and Roussel M.F. Regulation of cell growth and differentiation by the colony-stimulating factor 1 receptor. Seminars in Hematology 28 (1991) 143-151
259. Yarden Y., Kuang W.J., Yang-Feng T., Coussens L., Munemitsu S., Dull T.J., et al. Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO Journal 6 (1987) 3341-3351
260. Rosnet O., Marchetto S., deLapeyriere O., and Birnbaum D. Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family. Oncogene 6 (1991) 1641-1650
261. Rosnet O., Schiff C., Pebusque M.J., Marchetto S., Tonnelle C., Toiron Y., et al. Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells. Blood 82 (1993) 1110-1119
262. Claesson-Welsh L., Eriksson A., Westermark B., and Heldin C.H. cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor. Proceedings of the National Academy of Sciences 86 (1989) 4917-4921
263. Claesson-Welsh L., Eriksson A., Westermark B., and Heldin C.H. Cloning and expression of human platelet-derived growth factor alpha and beta receptors. Methods in Enzymology 198 (1991) 72-77
264. Yarden Y., Escobedo J.A., Kuang W.J., Yang-Feng T.L., Daniel T.O., Tremble P.M., et al. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature 323 (1986) 226-232
265. Lee A.W., and Nienhuis A.W. Functional dissection of structural domains in the receptor for colony-stimulating factor-1. Journal of Biological Chemistry 267 (1992) 16472-16483
266. Sasmono R.T., Ehrnsperger A., Cronau S.L., Ravasi T., Kandane R., Hickey M.J., et al. Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1. Journal of Leukocyte Biology 82 (2007) 111-123
267. Hofstetter W., Wetterwald A., Cecchini M.C., Felix R., Fleisch H., and Mueller C. Detection of transcripts for the receptor for macrophage colony-stimulating factor, c-fms, in murine osteoclasts. Proceedings of the National Academy of Sciences 89 (1992) 9637-9641
268. Hofstetter W., Wetterwald A., Cecchini M.G., Mueller C., and Felix R. Detection of transcripts and binding sites for colony-stimulating factor-1 during bone development. Bone 17 (1995) 145-151
269. Arceci R.J., Pampfer S., and Pollard J.W. Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development. Developmental Biology 151 (1992) 1-8
270. Pollard J.W., Bartocci A., Arceci R., Orlofsky A., Ladner M.B., and Stanley E.R. Apparent role of the macrophage growth factor, CSF-1, in placental development. Nature 330 (1987) 484-486
271. Sapi E., Flick M.B., Rodov S., Carter D., and Kacinski B.M. Expression of CSF-I and CSF-I receptor by normal lactating mammary epithelial cells. Journal of the Society for Gynecologic Investigation 5 (1998) 94-101
272. Wang Y., Berezovska O., and Fedoroff S. Expression of colony stimulating factor-1 receptor (CSF-1R) by CNS neurons in mice. Journal of Neuroscience Research 57 (1999) 616-632
273. Ashmun R.A., Look A.T., Roberts W.M., Roussel M.F., Seremetis S., Ohtsuka M., et al. Monoclonal antibodies to the human CSF-1 receptor (c-fms proto-oncogene product) detect epitopes on normal mononuclear phagocytes and on human myeloid leukemic blast cells. Blood 73 (1989) 827-837
274. Sapi E., and Kacinski B.M. The role of CSF-1 in normal and neoplastic breast physiology. Proceedings of the Society for Experimental Biology and Medicine Society for Experimental Biology and Medicine 220 (1999) 1-8
275. Toy E.P., Chambers J.T., Kacinski B.M., Flick M.B., and Chambers S.K. The activated macrophage colony-stimulating factor (CSF-1) receptor as a predictor of poor outcome in advanced epithelial ovarian carcinoma. Gynecologic Oncology 80 (2001) 194-200
276. Inaba T., Gotoda T., Harada K., Shimada M., Ohsuga J., Ishibashi S., et al. Induction of sustained expression of proto-oncogene c-fms by platelet-derived growth factor, epidermal growth factor, and basic fibroblast growth factor, and its suppression by interferon-gamma and macrophage colony-stimulating factor in human aortic medial smooth muscle cells. The Journal of Clinical Investigation 95 (1995) 1133-1139
277. Lee A.W., and States D.J. Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells. Cell Death and Differentiation 13 (2006) 1900-1914
278. Bartocci A., Mastrogiannis D.S., Migliorati G., Stockert R.J., Wolkoff A.W., and Stanley E.R. Macrophages specifically regulate the concentration of their own growth factor in the circulation. Proceedings of the National Academy of Sciences 84 (1987) 6179-6183
279. Guilbert L.J., and Stanley E.R. The interaction of 125I-colony-stimulating factor-1 with bone marrow-derived macrophages. Journal of Biological Chemistry 261 (1986) 4024-4032
280. Tushinski R.J., Oliver I.T., Guilbert L.J., Tynan P.W., Warner J.R., and Stanley E.R. Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy. Cell 28 (1982) 71-81
281. Tushinski R.J., and Stanley E.R. The regulation of macrophage protein turnover by a colony stimulating factor (CSF-1). Journal of Cell Physiology 116 (1983) 67-75
282. Mancini A., Koch A., Wilms R., and Tamura T. c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms. Journal of Biological Chemistry 277 (2002) 14635-14640
283. Wang Y., Yeung Y.G., Langdon W.Y., and Stanley E.R. c-Cbl is transiently tyrosine-phosphorylated, ubiquitinated, and membrane-targeted following CSF-1 stimulation of macrophages. Journal of Biological Chemistry 271 (1996) 17-20
284. Wang Y., Yeung Y.G., and Stanley E.R. CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins. Journal of Cell Biochemistry 72 (1999) 119-134
285. Wilhelmsen K., Burkhalter S., and van der Geer P. C-Cbl binds the CSF-1 receptor at tyrosine 973, a novel phosphorylation site in the receptor's carboxy-terminus. Oncogene 21 (2002) 1079-1089
286. Suzu S., Tanaka-Douzono M., Nomaguchi K., Yamada M., Hayasawa H., Kimura F., et al. p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction. EMBO Journal 19 (2000) 5114-5122
287. Niki M., Di Cristofano A., Zhao M., Honda H., Hirai H., Van Aelst L., et al. Role of Dok-1 and Dok-2 in leukemia suppression. The Journal of Experimental Medicine 200 (2004) 1689-1695
288. Novak U., Marks D., Nicholson S.E., Hilton D., and Paradiso L. Differential ability of SOCS proteins to regulate IL-6 and CSF-1 induced macrophage differentiation. Growth Factors 16 (1999) 305-314
289. Bourette R.P., De Sepulveda P., Arnaud S., Dubreuil P., Rottapel R., and Mouchiroud G. Suppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signal. Journal of Biological Chemistry 276 (2001) 22133-22139
290. Chen H.E., Chang S., Trub T., and Neel B.G. Regulation of colony-stimulating factor 1 receptor signaling by the SH2 domain-containing tyrosine phosphatase SHPTP1. Molecular Cell Biology 16 (1996) 3685-3697
291. Oshibe T., Kitamura I., Tanaka K., Baba T., Kodama H., Mukamoto M., et al. Epidermal tissue-derived T-cell growth factor, colony stimulating factor and nerve growth factor in chickens. Zentralblatt fur Veterinarmedizin Reihe B. Journal of Veterinary Medicine 46 (1999) 389-398
292. Shao X., Kikuchi K., Watari E., Norose Y., Araki T., and Yokomuro K. Changes in M-CSF-like activity during chicken embryonic development. Reproduction, Fertility and Development 8 (1996) 103-109
293. Chaves-Pozo E., Liarte S., Fernandez-Alacid L., Abellan E., Meseguer J., Mulero V., et al. Pattern of expression of immune-relevant genes in the gonad of a teleost, the gilthead seabream (Sparus aurata L.). Molecular Immunology 45 (2008) 2998-3011
294. Roca F.J., Sepulcre M.A., Lopez-Castejon G., Meseguer J., and Mulero V. The colony-stimulating factor-1 receptor is a specific marker of macrophages from the bony fish gilthead seabream. Molecular Immunology 43 (2006) 1418-1423
295. Honda T., Nishizawa T., Uenobe M., Kohchi C., Kuroda A., Ototake M., et al. Molecular cloning and expression analysis of a macrophage-colony stimulating factor receptor-like gene from rainbow trout, Oncorhynchus mykiss. Molecular Immunology 42 (2005) 1-8
296. Wang T., Hanington P.C., Belosevic M., and Secombes C.J. Two macrophage colony-stimulating factor genes exist in fish that differ in gene organization and are differentially expressed. Journal of Immunology 181 (2008) 3310-3322
297. Hanington PC, Hitchen SJ, Beamish LA, Belosevic M. Macrophage colony stimulating factor (CSF-1) is a central growth factor of goldfish macrophages. Fish and Shellfish Immunology, in press.
298. Bateman A., and Bennett H.P. Granulins: the structure and function of an emerging family of growth factors. Journal of Endocrinology 158 (1998) 145-151
299. Zhou J., Gao G., Crabb J.W., and Serrero G. Purification of an autocrine growth factor homologous with mouse epithelin precursor from a highly tumorigenic cell line. Journal of Biological Chemistry 268 (1993) 10863-10869
300. Pan C.X., Kinch M.S., Kiener P.A., Langermann S., Serrero G., Sun L., et al. PC cell-derived growth factor expression in prostatic intraepithelial neoplasia and prostatic adenocarcinoma. Clinical Cancer Research 10 (2004) 1333-1337
301. Jones M.B., Houwink A.P., Freeman B.K., Greenwood T.M., Lafky J.M., Lingle W.L., et al. The granulin-epithelin precursor is a steroid-regulated growth factor in endometrial cancer. Journal of the Society for Gynecologic Investigation 13 (2006) 304-311
302. Donald C.D., Laddu A., Chandham P., Lim S.D., Cohen C., Amin M., et al. Expression of progranulin and the epithelin/granulin precursor acrogranin correlates with neoplastic state in renal epithelium. Anticancer Research 21 (2001) 3739-3742
303. He Z., and Bateman A. Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo. Cancer Research 59 (1999) 3222-3229
304. Liau L.M., Lallone R.L., Seitz R.S., Buznikov A., Gregg J.P., Kornblum H.I., et al. Identification of a human glioma-associated growth factor gene, granulin, using differential immuno-absorption. Cancer Research 60 (2000) 1353-1360
305. Zhang H., and Serrero G. Inhibition of tumorigenicity of the teratoma PC cell line by transfection with antisense cDNA for PC cell-derived growth factor (PCDGF, epithelin/granulin precursor). Proceedings of the National Academy of Sciences 95 (1998) 14202-14207
306. He Z., Ong C.H., Halper J., and Bateman A. Progranulin is a mediator of the wound response. Nature Medicine 9 (2003) 225-229
307. Cadieux B., Chitramuthu B.P., Baranowski D., and Bennett H.P. The zebrafish progranulin gene family and antisense transcripts. BMC Genomics 6 (2005) 156
308. Diaz-Cueto L., Stein P., Jacobs A., Schultz R.M., and Gerton G.L. Modulation of mouse preimplantation embryo development by acrogranin (epithelin/granulin precursor). Developmental Biology 217 (2000) 406-418
309. Lee H.C., Yamanouchi K., and Nishihara M. Effects of perinatal exposure to phthalate/adipate esters on hypothalamic gene expression and sexual behavior in rats. Journal of Reproduction and Development 52 (2006) 343-352
310. Suzuki M., and Nishiahara M. Granulin precursor gene: a sex steroid-inducible gene involved in sexual differentiation of the rat brain. Molecular Genetics and Metabolism 75 (2002) 31-37
311. Suzuki M., Yoshida S., Nishihara M., and Takahashi M. Identification of a sex steroid-inducible gene in the neonatal rat hypothalamus. Neuroscience Letters 242 (1998) 127-130
312. Chiba S., Suzuki M., Yamanouchi K., and Nishihara M. Involvement of granulin in estrogen-induced neurogenesis in the adult rat hippocampus. Journal of Reproduction and Development 53 (2007) 297-307
313. Eriksen J.L., and Mackenzie I.R. Progranulin: normal function and role in neurodegeneration. Journal of Neurochemistry 104 (2008) 287-297
314. Baker M., Mackenzie I.R., Pickering-Brown S.M., Gass J., Rademakers R., Lindholm C., et al. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 442 (2006) 916-919
315. He Z., and Bateman A. Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis. Journal of Molecular Medicine 81 (2003) 600-612
316. Zhu J., Nathan C., Jin W., Sim D., Ashcroft G.S., Wahl S.M., et al. Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell 111 (2002) 867-878
317. Plowman G.D., Green J.M., Neubauer M.G., Buckley S.D., McDonald V.L., Todaro G.J., et al. The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth. Journal of Biological Chemistry 267 (1992) 13073-13078
318. Baba T., Hoff III H.B., Nemoto H., Lee H., Orth J., Arai Y., et al. Acrogranin, an acrosomal cysteine-rich glycoprotein, is the precursor of the growth-modulating peptides, granulins, and epithelins, and is expressed in somatic as well as male germ cells. Molecular Reproduction and Development 34 (1993) 233-243
319. Bateman A., Belcourt D., Bennett H., Lazure C., and Solomon S. Granulins, a novel class of peptide from leukocytes. Biochemical and Biophysics Research Communication 173 (1990) 1161-1168
320. Hrabal R., Chen Z., James S., Bennett H.P., and Ni F. The hairpin stack fold, a novel protein architecture for a new family of protein growth factors. Nature Structural Biology 3 (1996) 747-752
321. Chen H.J., Huang D.J., Hou W.C., Liu J.S., and Lin Y.H. Molecular cloning and characterization of a granulin-containing cysteine protease SPCP3 from sweet potato (Ipomoea batatas) senescent leaves. Journal of Plant Physiology 163 (2006) 863-876
322. Chen M.H., Li Y.H., Chang Y., Hu S.Y., Gong H.Y., Lin G.H., et al. Co-induction of hepatic IGF-I and progranulin mRNA by growth hormone in tilapia, Oreochromis mossambiccus. General and Comparative Endocrinology 150 (2007) 212-218
323. Ong C.H., He Z., Kriazhev L., Shan X., Palfree R.G., and Bateman A. Regulation of progranulin expression in myeloid cells. American Journal of Physiology 291 (2006) R1602-R1612
324. Chantry D., DeMaggio A.J., Brammer H., Raport C.J., Wood C.L., Schweickart V.L., et al. Profile of human macrophage transcripts: insights into macrophage biology and identification of novel chemokines. Journal of Leukocyte Biology 64 (1998) 49-54
325. Hashimoto S., Suzuki T., Dong H.Y., Nagai S., Yamazaki N., and Matsushima K. Serial analysis of gene expression in human monocyte-derived dendritic cells. Blood 94 (1999) 845-852
326. Hashimoto S., Suzuki T., Dong H.Y., Yamazaki N., and Matsushima K. Serial analysis of gene expression in human monocytes and macrophages. Blood 94 (1999) 837-844
327. Bhandari V., Palfree R.G., and Bateman A. Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains. Proceedings of the National Academy of Sciences 89 (1992) 1715-1719
328. Daniel R., He Z., Carmichael K.P., Halper J., and Bateman A. Cellular localization of gene expression for progranulin. Journal of Histochemistry and Cytochemistry 48 (2000) 999-1009
329. Nara K., Matsue H., and Naraoka T. Granulin-like peptide in the mid-gut gland of the bivalve mollusk, Patinopecten yessoensis. Biochimica et Biophysica Acta 1675 (2004) 147-154
330. Nakakura N., Hietter H., Van Dorsselaer A., and Luu B. Isolation and structural determination of three peptides from the insect Locusta migratoria. Identification of a deoxyhexose-linked peptide. European Journal of Biochemistry/FEBS 204 (1992) 147-153
331. Deloffre L., Salzet B., Vieau D., Andries J.C., and Salzet M. Antibacterial properties of hemerythrin of the sand worm Nereis diversicolor. Neuroendocrinology Letters 24 (2003) 39-45
332. Hanington P.C., Brennan L.J., Belosevic M., and Keddie B.A. Molecular and functional characterization of granulin-like molecules of insects. Insect Biochemistry and Molecular Biology 38 (2008) 596-603
333. Couto M.A., Harwig S.S., Cullor J.S., Hughes J.P., and Lehrer R.I. Identification of eNAP-1, an antimicrobial peptide from equine neutrophils. Infection and Immunity 60 (1992) 3065-3071
334. Xu K., Zhang Y., Ilalov K., Carlson C.S., Feng J.Q., Di Cesare P.E., et al. Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. Journal of Biological Chemistry 282 (2007) 11347-11355
335. Liu Y., Xi L., Liao G., Wang W., Tian X., Wang B., et al. Inhibition of PC cell-derived growth factor (PCDGF)/granulin-epithelin precursor (GEP) decreased cell proliferation and invasion through downregulation of cyclin D and CDK4 and inactivation of MMP-2. BMC Cancer 7 (2007) 22
336. Shoyab M., McDonald V.L., Byles C., Todaro G.J., and Plowman G.D. Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins. Proceedings of the National Academy of Sciences 87 (1990) 7912-7916
337. Metcalf D. The unsolved enigmas of leukemia inhibitory factor. Stem Cells 21 (2003) 5-14
338. Bauer S., and Patterson P.H. Leukemia inhibitory factor promotes neural stem cell self-renewal in the adult brain. Journal of Neuroscience 26 (2006) 12089-12099
339. Eckert J., and Niemann H. mRNA expression of leukaemia inhibitory factor (LIF) and its receptor subunits glycoprotein 130 and LIF-receptor-beta in bovine embryos derived in vitro or in vivo. Molecular Human Reproduction 4 (1998) 957-965
340. Smith A.G., Nichols J., Robertson M., and Rathjen P.D. Differentiation inhibiting activity (DIA/LIF) and mouse development. Developmental Biology 151 (1992) 339-351
341. Williams R.L., Hilton D.J., Pease S., Willson T.A., Stewart C.L., Gearing D.P., et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336 (1988) 684-687
342. Bonaguidi M.A., McGuire T., Hu M., Kan L., Samanta J., and Kessler J.A. LIF and BMP signaling generate separate and discrete types of GFAP-expressing cells. Development 132 (2005) 5503-5514
343. Gregg C., and Weiss S. CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain. Development 132 (2005) 565-578
344. Pitman M., Emery B., Binder M., Wang S., Butzkueven H., and Kilpatrick T.J. LIF receptor signaling modulates neural stem cell renewal. Molecular Cell Neurosci 27 (2004) 255-266
345. Wright L.S., Li J., Caldwell M.A., Wallace K., Johnson J.A., and Svendsen C.N. Gene expression in human neural stem cells: effects of leukemia inhibitory factor. Journal of Neurochemistry 86 (2003) 179-195
346. Chojnacki A., Shimazaki T., Gregg C., Weinmaster G., and Weiss S. Glycoprotein 130 signaling regulates Notch1 expression and activation in the self-renewal of mammalian forebrain neural stem cells. Journal of Neuroscience 23 (2003) 1730-1741
347. Hitoshi S., Alexson T., Tropepe V., Donoviel D., Elia A.J., Nye J.S., et al. Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes and Development 16 (2002) 846-858
348. Bauer S., Rasika S., Han J., Mauduit C., Raccurt M., Morel G., et al. Leukemia inhibitory factor is a key signal for injury-induced neurogenesis in the adult mouse olfactory epithelium. Journal of Neuroscience 23 (2003) 1792-1803
349. Koblar S.A., Turnley A.M., Classon B.J., Reid K.L., Ware C.B., Cheema S.S., et al. Neural precursor differentiation into astrocytes requires signaling through the leukemia inhibitory factor receptor. Proceedings of the National Academy of Sciences 95 (1998) 3178-3181
350. Hilton D.J., Nicola N.A., and Metcalf D. Purification of a murine leukemia inhibitory factor from Krebs ascites cells. Analytical Biochemistry 173 (1988) 359-367
351. Gearing D.P., Gough N.M., King J.A., Hilton D.J., Nicola N.A., Simpson R.J., et al. Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). EMBO Journal 6 (1987) 3995-4002
352. Metcalf D., Hilton D.J., and Nicola N.A. Clonal analysis of the actions of the murine leukemia inhibitory factor on leukemic and normal murine hemopoietic cells. Leukemia 2 (1988) 216-221
353. Metcalf D., Hilton D., and Nicola N.A. Leukemia inhibitory factor can potentiate murine megakaryocyte production in vitro. Blood 77 (1991) 2150-2153
354. Metcalf D. Murine hematopoietic stem cells committed to macrophage/dendritic cell formation: stimulation by Flk2-ligand with enhancement by regulators using the gp130 receptor chain. Proceedings of the National Academy of Sciences 94 (1997) 11552-11556
355. Escary J.L., Perreau J., Dumenil D., Ezine S., and Brulet P. Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation. Nature 363 (1993) 361-364
356. Jiang Y., Vaessen B., Lenvik T., Blackstad M., Reyes M., and Verfaillie C.M. Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain. Experimental Hematology 30 (2002) 896-904
357. Leary A.G., Wong G.G., Clark S.C., Smith A.G., and Ogawa M. Leukemia inhibitory factor differentiation-inhibiting activity/human interleukin for DA cells augments proliferation of human hematopoietic stem cells. Blood 75 (1990) 1960-1964
358. Banner L.R., Moayeri N.N., and Patterson P.H. Leukemia inhibitory factor is expressed in astrocytes following cortical brain injury. Experimental Neurology 147 (1997) 1-9
359. Dowsing B.J., Romeo R., and Morrison W.A. Expression of leukemia inhibitory factor in human nerve following injury. Journal of Neurotrauma 18 (2001) 1279-1287
360. Sugiura S., Lahav R., Han J., Kou S.Y., Banner L.R., de Pablo F., et al. Leukaemia inhibitory factor is required for normal inflammatory responses to injury in the peripheral and central nervous systems in vivo and is chemotactic for macrophages in vitro. The European Journal of Neuroscience 12 (2000) 457-466
361. Suzuki S., Yamashita T., Tanaka K., Hattori H., Sawamoto K., Okano H., et al. Activation of cytokine signaling through leukemia inhibitory factor receptor (LIFR)/gp130 attenuates ischemic brain injury in rats. Journal of Cerebral Blood Flow & Metabolism 25 (2005) 685-693
362. Rao M.S., Sun Y., Escary J.L., Perreau J., Tresser S., Patterson P.H., et al. Leukemia inhibitory factor mediates an injury response but not a target-directed developmental transmitter switch in sympathetic neurons. Neuron 11 (1993) 1175-1185
363. Corness J., Shi T.J., Xu Z.Q., Brulet P., and Hokfelt T. Influence of leukemia inhibitory factor on galanin/GMAP and neuropeptide Y expression in mouse primary sensory neurons after axotomy. Experimental Brain Research Experimentelle Hirnforschung 112 (1996) 79-88
364. Holmberg K.H., and Patterson P.H. Leukemia inhibitory factor is a key regulator of astrocytic, microglial and neuronal responses in a low-dose pilocarpine injury model. Brain Research 1075 (2006) 26-35
365. Kerr B.J., and Patterson P.H. Potent pro-inflammatory actions of leukemia inhibitory factor in the spinal cord of the adult mouse. Experimental Neurology 188 (2004) 391-407
366. Yamamori T., Fukada K., Aebersold R., Korsching S., Fann M.J., and Patterson P.H. The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor. Science (New York, NY) 246 (1989) 1412-1416
367. Bamber B.A., Masters B.A., Hoyle G.W., Brinster R.L., and Palmiter R.D. Leukemia inhibitory factor induces neurotransmitter switching in transgenic mice. Proceedings of the National Academy of Sciences 91 (1994) 7839-7843
368. Francis N.J., Asmus S.E., and Landis S.C. CNTF and LIF are not required for the target-directed acquisition of cholinergic and peptidergic properties by sympathetic neurons in vivo. Developmental Biology 182 (1997) 76-87
369. Habecker B.A., Symes A.J., Stahl N., Francis N.J., Economides A., Fink J.S., et al. A sweat gland-derived differentiation activity acts through known cytokine signaling pathways. Journal of Biological Chemistry 272 (1997) 30421-30428
370. Stewart C.L., Kaspar P., Brunet L.J., Bhatt H., Gadi I., Kontgen F., et al. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 359 (1992) 76-79
371. Chen J.R., Cheng J.G., Shatzer T., Sewell L., Hernandez L., and Stewart C.L. Leukemia inhibitory factor can substitute for nidatory estrogen and is essential to inducing a receptive uterus for implantation but is not essential for subsequent embryogenesis. Endocrinology 141 (2000) 4365-4372
372. Fujiki K., Nakao M., and Dixon B. Molecular cloning and characterisation of a carp (Cyprinus carpio) cytokine-like cDNA that shares sequence similarity with IL-6 subfamily cytokines CNTF, OSM and LIF. Developmental and Comparative Immunology 27 (2003) 127-136
373. Huising M.O., Kruiswijk C.P., van Schijndel J.E., Savelkoul H.F., Flik G., and Verburg-van Kemenade B.M. Multiple and highly divergent IL-11 genes in teleost fish. Immunogenetics 57 (2005) 432-443
374. Hanington P.C., Patten S.A., Reaume L.M., Waskiewicz A.J., Belosevic M., and Ali D.W. Analysis of leukemia inhibitory factor and leukemia inhibitory factor receptor in embryonic and adult zebrafish (Danio rerio). Developmental Biology 314 (2008) 250-260
375. Nam B.H., Byon J.Y., Kim Y.O., Park E.M., Cho Y.C., and Cheong J. Molecular cloning and characterisation of the flounder (Paralichthys olivaceus) interleukin-6 gene. Fish and Shellfish Immunology 23 (2007) 231-236
376. Bird S., Zou J., Savan R., Kono T., Sakai M., Woo J., et al. Characterisation and expression analysis of an interleukin 6 homologue in the Japanese pufferfish, Fugu rubripes. Developmental and Comparative Immunology 29 (2005) 775-789
377. Hwang J.Y., Santos M.D., Kondo H., Hirono I., and Aoki T. Identification, characterization and expression of a novel cytokine M17 homologue (MSH) in fish. Fish and Shellfish Immunology 23 (2007) 1256-1265
378. Iliev D.B., Castellana B., Mackenzie S., Planas J.V., and Goetz F.W. Cloning and expression analysis of an IL-6 homolog in rainbow trout (Oncorhynchus mykiss). Molecular Immunology 44 (2007) 1803-1807
379. Wang T., Holland J.W., Bols N., and Secombes C.J. Cloning and expression of the first nonmammalian interleukin-11 gene in rainbow trout Oncorhynchus mykiss. FEBS Journal 272 (2005) 1136-1147
380. Santos M.D., Yasuike M., Hirono I., and Aoki T. The granulocyte colony-stimulating factors (CSF3s) of fish and chicken. Immunogenetics 58 (2006) 422-432
381. Ballen K. Targeting the stem cell niche: squeezing blood from bones. Bone Marrow Transplantation 39 (2007) 655-660
382. Cutler C., and Antin J.H. An overview of hematopoietic stem cell transplantation. Clinics in Chest Medicine 26 (2005) 517-527 v
383. White R.M., Sessa A., Burke C., Bowman T., LeBlanc J., Ceol C., et al. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell 2 (2008) 183-189
384. Traver D., Paw B.H., Poss K.D., Penberthy W.T., Lin S., and Zon L.I. Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature Immunology 4 (2003) 1238-1246
385. Traver D., Winzeler A., Stern H.M., Mayhall E.A., Langenau D.M., Kutok J.L., et al. Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood 104 (2004) 1298-1305
386. Bunting K.D. ABC transporters as phenotypic markers and functional regulators of stem cells. Stem Cells (Dayton, Ohio) 20 (2002) 11-20
387. Kobayashi I., Kuniyoshi S., Saito K., Moritomo T., Takahashi T., and Nakanishi T. Long-term hematopoietic reconstitution by transplantation of kidney hematopoietic stem cells in lethally irradiated clonal ginbuna crucian carp (Carassius auratus langsdorfii). Developmental and Comparative Immunology 32 (2008) 957-965
388. Kobayashi I., Kusakabe H., Toda H., Moritomo T., Takahashi T., and Nakanishi T. In vivo characterization of primitive hematopoietic cells in clonal ginbuna crucian carp (Carassius auratus langsdorfii). Veterinary Immunology and Immunopathology 126 (2008) 74-82
389. Tsinkalovsky O., Vik-Mo A.O., Ferreira S., Laerum O.D., and Fjose A. Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties. Differentiation 75 (2007) 175-183
390. Kobayashi I., Saito K., Moritomo T., Araki K., Takizawa F., and Nakanishi T. Characterization and localization of side population (SP) cells in zebrafish kidney hematopoietic tissue. Blood 111 (2008) 1131-1137