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Volumn 18, Issue 20, 1999, Pages 5666-5674

The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1

Author keywords

Conformational change; Elk 1; ETS domain; Phosphorylation; Transcription factor

Indexed keywords

DNA; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

EID: 0033570227     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.20.5666     Document Type: Article
Times cited : (98)

References (36)
  • 1
    • 0028793798 scopus 로고
    • Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation
    • Cavigelli, M., Dolfi, F., Claret, F.X. and Karin, M. (1995) Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation. EMBO J., 14, 5957-5964.
    • (1995) EMBO J. , vol.14 , pp. 5957-5964
    • Cavigelli, M.1    Dolfi, F.2    Claret, F.X.3    Karin, M.4
  • 2
    • 0026556859 scopus 로고
    • Characterisation of SAP-1, a protein recruited by serum response factor to the c-fos serum response element
    • Dalton, S. and Treisman, R. (1992) Characterisation of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell, 68, 597-612.
    • (1992) Cell , vol.68 , pp. 597-612
    • Dalton, S.1    Treisman, R.2
  • 3
    • 0029379778 scopus 로고
    • Activation of ternary complex factor Elk-1 by stress-activated protein kinases
    • Gille, H., Strahl, T. and Shaw, P.E. (1995) Activation of ternary complex factor Elk-1 by stress-activated protein kinases. Curr. Biol., 5, 1191-1200.
    • (1995) Curr. Biol. , vol.5 , pp. 1191-1200
    • Gille, H.1    Strahl, T.2    Shaw, P.E.3
  • 4
    • 0030027491 scopus 로고    scopus 로고
    • Phosphorylation-dependent formation of a quaternary complex at the c-fos SRE
    • Gille, H., Kortenjann, M., Strahl, T. and Shaw, P.E. (1996) Phosphorylation-dependent formation of a quaternary complex at the c-fos SRE. Mol. Cell. Biol., 16, 1094-1102.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1094-1102
    • Gille, H.1    Kortenjann, M.2    Strahl, T.3    Shaw, P.E.4
  • 5
    • 0031688174 scopus 로고    scopus 로고
    • Specificity within the ets family of transcription factors
    • Graves, B.J. and Petersen, J.M. (1998) Specificity within the ets family of transcription factors. Adv. Cancer Res., 75, 1-55.
    • (1998) Adv. Cancer Res. , vol.75 , pp. 1-55
    • Graves, B.J.1    Petersen, J.M.2
  • 6
    • 0025977037 scopus 로고
    • Eukaryotic proteins expressed in Escherichia coli, an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
    • Guan, K. and Dixon, J.E. (1991) Eukaryotic proteins expressed in Escherichia coli, an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem., 192, 262-267.
    • (1991) Anal. Biochem. , vol.192 , pp. 262-267
    • Guan, K.1    Dixon, J.E.2
  • 7
    • 0028897113 scopus 로고
    • Transcriptional regulation by extracellular signals: Mechanisms and specificity
    • Hill, C.S. and Treisman, R. (1995) Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell, 80, 199-211.
    • (1995) Cell , vol.80 , pp. 199-211
    • Hill, C.S.1    Treisman, R.2
  • 8
    • 0026636883 scopus 로고
    • The regulation of transcription by phosphorylation
    • Hunter, T. and Karin, M. (1992) The regulation of transcription by phosphorylation. Cell, 70, 375-387.
    • (1992) Cell , vol.70 , pp. 375-387
    • Hunter, T.1    Karin, M.2
  • 9
    • 0028845158 scopus 로고
    • Small latent peptides activate the latent sequence-specific DNA binding function of p53
    • Hupp, T.R., Sparks, A. and Lane, D.P. (1995) Small latent peptides activate the latent sequence-specific DNA binding function of p53. Cell, 83, 237-245.
    • (1995) Cell , vol.83 , pp. 237-245
    • Hupp, T.R.1    Sparks, A.2    Lane, D.P.3
  • 10
    • 0028281480 scopus 로고
    • Functional dissection of the transcription factor Elk-1
    • Janknecht, R., Zinck, R., Ernst, W.H. and Nordheim, A. (1994) Functional dissection of the transcription factor Elk-1. Oncogene, 9, 1273-1278.
    • (1994) Oncogene , vol.9 , pp. 1273-1278
    • Janknecht, R.1    Zinck, R.2    Ernst, W.H.3    Nordheim, A.4
  • 11
    • 0029958777 scopus 로고    scopus 로고
    • Characterisation of the co-operative function of inhibitory sequences in Ets-1
    • Jonsen, M.D., Petersen, J.M., Xu, Q-P. and Graves, B.J. (1996) Characterisation of the co-operative function of inhibitory sequences in Ets-1. Mol. Cell. Biol., 16, 2065-2073.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2065-2073
    • Jonsen, M.D.1    Petersen, J.M.2    Xu, Q.-P.3    Graves, B.J.4
  • 12
    • 0032580207 scopus 로고    scopus 로고
    • Allosteric effects of DNA on transcriptional regulators
    • Lefstin, J.F. and Yamamoto, K.R. (1998) Allosteric effects of DNA on transcriptional regulators. Nature, 392, 885-888.
    • (1998) Nature , vol.392 , pp. 885-888
    • Lefstin, J.F.1    Yamamoto, K.R.2
  • 13
    • 0030921505 scopus 로고    scopus 로고
    • Molecular characteristics of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1
    • Ling, Y., Lakey, J.H., Roberts, C.E. and Sharrocks, A.D. (1997) Molecular characteristics of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1. EMBO J., 16, 2431-2440.
    • (1997) EMBO J. , vol.16 , pp. 2431-2440
    • Ling, Y.1    Lakey, J.H.2    Roberts, C.E.3    Sharrocks, A.D.4
  • 14
    • 0029956658 scopus 로고    scopus 로고
    • Net (ERP/SAP2), one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif
    • Maira, S-M., Wurtz, J.-M. and Wasylyk, B. (1996) Net (ERP/SAP2), one of the Ras-inducible TCFs, has a novel inhibitory domain with resemblance to the helix-loop-helix motif. EMBO J., 15, 5849-5865.
    • (1996) EMBO J. , vol.15 , pp. 5849-5865
    • Maira, S.-M.1    Wurtz, J.-M.2    Wasylyk, B.3
  • 15
    • 0023656828 scopus 로고
    • Variable selection method improves the prediction of protein secondary structure from circular dichroism spectra
    • Manavalan, P. and Johnson, W.C. (1987) Variable selection method improves the prediction of protein secondary structure from circular dichroism spectra. Anal. Biochem., 167, 76-85.
    • (1987) Anal. Biochem. , vol.167 , pp. 76-85
    • Manavalan, P.1    Johnson, W.C.2
  • 16
    • 0029562554 scopus 로고
    • The RXR heterodimers and orphan receptors
    • Mangelsdorf, D.J. and Evans, R.M. (1995) The RXR heterodimers and orphan receptors. Cell, 83, 841-850.
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 17
    • 0027297647 scopus 로고
    • The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
    • Marais, R., Wynne, J. and Treisman, R. (1993) The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell, 73, 381-393.
    • (1993) Cell , vol.73 , pp. 381-393
    • Marais, R.1    Wynne, J.2    Treisman, R.3
  • 18
    • 0028874393 scopus 로고
    • Modulation of transcripton factor Ets-1 DNA binding: DNA-induced unfolding of an α-helix
    • Petersen, J.M., Skalicky, J.J., Donaldson, L.W., McIntosh, L.P., Alber, T. and Graves, B.J. (1995) Modulation of transcripton factor Ets-1 DNA binding: DNA-induced unfolding of an α-helix. Science, 269, 1866-1869.
    • (1995) Science , vol.269 , pp. 1866-1869
    • Petersen, J.M.1    Skalicky, J.J.2    Donaldson, L.W.3    McIntosh, L.P.4    Alber, T.5    Graves, B.J.6
  • 19
    • 0029827366 scopus 로고    scopus 로고
    • The p38 and ERK MAP kinase pathways co-operate to activate ternary complex factors and c-fos transcription in response to UV light
    • Price, M.A., Cruzalegui, F.H. and Treisman, R. (1996) The p38 and ERK MAP kinase pathways co-operate to activate ternary complex factors and c-fos transcription in response to UV light. EMBO J., 15, 6552-6563.
    • (1996) EMBO J. , vol.15 , pp. 6552-6563
    • Price, M.A.1    Cruzalegui, F.H.2    Treisman, R.3
  • 20
    • 0028079760 scopus 로고
    • Activator-induced conformational change in general transcription factor TFIIB
    • Roberts, S.G.E. and Green, M.R. (1994) Activator-induced conformational change in general transcription factor TFIIB. Nature, 371, 717-720.
    • (1994) Nature , vol.371 , pp. 717-720
    • Roberts, S.G.E.1    Green, M.R.2
  • 21
    • 0028998013 scopus 로고
    • ERK2/p42 MAP kinase stimulates both autonomous and SRF-dependent DNA binding by Elk-1
    • Sharrocks, A.D. (1995) ERK2/p42 MAP kinase stimulates both autonomous and SRF-dependent DNA binding by Elk-1. FEBS Lett., 368, 77-80.
    • (1995) FEBS Lett. , vol.368 , pp. 77-80
    • Sharrocks, A.D.1
  • 22
    • 0029035319 scopus 로고
    • DNA bending in the ternary nucleoprotein complex at the c-fos promoter
    • Sharrocks, A.D. and Shore, P. (1995) DNA bending in the ternary nucleoprotein complex at the c-fos promoter. Nucleic Acids Res., 23, 2442-2449.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 2442-2449
    • Sharrocks, A.D.1    Shore, P.2
  • 24
    • 0028211125 scopus 로고
    • The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1
    • Shore, P. and Sharrocks, A.D. (1994) The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1. Mol. Cell. Biol., 14, 3283-3291.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3283-3291
    • Shore, P.1    Sharrocks, A.D.2
  • 27
    • 0029908198 scopus 로고    scopus 로고
    • Selective response of ternary complex factor Sap-1a to different mitogen-activated protein kinase sub-groups
    • Strahl, T., Gille, H. and Shaw, P.E. (1996) Selective response of ternary complex factor Sap-1a to different mitogen-activated protein kinase sub-groups. Proc. Natl Acad. Sci. USA, 93, 11563-11568.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 11563-11568
    • Strahl, T.1    Gille, H.2    Shaw, P.E.3
  • 28
    • 0026469669 scopus 로고
    • Spatial flexibility in complexes between SRF and its accesory proteins
    • Treisman, R., Marais, R. and Wynne, J. (1992) Spatial flexibility in complexes between SRF and its accesory proteins. EMBO J., 11, 4631-4640.
    • (1992) EMBO J. , vol.11 , pp. 4631-4640
    • Treisman, R.1    Marais, R.2    Wynne, J.3
  • 29
    • 0028084337 scopus 로고
    • Ternary complex factors: Growth regulated transcriptional activators
    • Treisman, R. (1994) Ternary complex factors: growth regulated transcriptional activators. Curr. Opin. Genet. Dev., 4, 96-101.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 96-101
    • Treisman, R.1
  • 30
    • 0029935418 scopus 로고    scopus 로고
    • Regulation of transcription by MAP kinase cascades
    • Treisman, R. (1996) Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol., 8, 205-215.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 205-215
    • Treisman, R.1
  • 31
    • 0029125757 scopus 로고
    • Integration of MAP kinase signal transduction pathways at the serum response element
    • Whitmarsh, A.J., Shore, P., Sharrocks, A.D. and Davis, R.J. (1995) Integration of MAP kinase signal transduction pathways at the serum response element. Science, 269, 403-407.
    • (1995) Science , vol.269 , pp. 403-407
    • Whitmarsh, A.J.1    Shore, P.2    Sharrocks, A.D.3    Davis, R.J.4
  • 32
  • 33
    • 0031882123 scopus 로고    scopus 로고
    • The Elk-1 ETS-domain transcription factor contains a MAP kinase targeting motif
    • Yang, S.-H., Yates, P.R., Whitmarsh, A.J., Davis, R.J. and Sharrocks, A.D. (1998a) The Elk-1 ETS-domain transcription factor contains a MAP kinase targeting motif. Mol. Cell. Biol., 18, 710-720.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 710-720
    • Yang, S.-H.1    Yates, P.R.2    Whitmarsh, A.J.3    Davis, R.J.4    Sharrocks, A.D.5
  • 34
    • 0032536816 scopus 로고    scopus 로고
    • Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1
    • Yang, S.-H., Whitmarsh, A.J., Davis, R.J. and Sharrocks, A.D. (1998b) Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO J., 17, 1740-1749.
    • (1998) EMBO J. , vol.17 , pp. 1740-1749
    • Yang, S.-H.1    Whitmarsh, A.J.2    Davis, R.J.3    Sharrocks, A.D.4
  • 35
    • 0000516028 scopus 로고    scopus 로고
    • The ETS-domain transcription factors: Lessons from the TCF subfamily
    • Yang, S.-H., Yates, P.R. and Sharrocks, A.D. (1998c) The ETS-domain transcription factors: lessons from the TCF subfamily. Gene Ther. Mol. Biol., 3, 355-371.
    • (1998) Gene Ther. Mol. Biol. , vol.3 , pp. 355-371
    • Yang, S.-H.1    Yates, P.R.2    Sharrocks, A.D.3
  • 36
    • 0027879410 scopus 로고
    • A gene expression vector useful for protein purification and studies of protein-protein interactions
    • Zhao, L.-J. and Narayan, O. (1993) A gene expression vector useful for protein purification and studies of protein-protein interactions. Gene, 137, 345-346.
    • (1993) Gene , vol.137 , pp. 345-346
    • Zhao, L.-J.1    Narayan, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.