ABC transporters as phenotypic markers and functional regulators of stem cells

Stem Cells

Volumn 20, Issue 1, 2002, Pages 11-20

  Bunting, Kevin D ^a  

^a HOLLAND LABORATORY   (United States)

Author keywords

ABC transporter; Bone marrow transplantation; Retrovirus vector; Stem cell

Indexed keywords

ABC TRANSPORTER; BREAST CANCER RESISTANCE PROTEIN; CD34 ANTIGEN; GENE PRODUCT; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; BLAST CELL; BONE MARROW CELL; CELL LINEAGE; CELL POPULATION; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MARKER GENE; MOUSE; NONHUMAN; PHENOTYPE; REVIEW; STEM CELL;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

EID: 0036163796     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.200011     Document Type: Review

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13. Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: Evidence against direct drag extrusion from the plasma membrane
14. MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
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19. -low/negative hematopoietic stem cell
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35. The transporter ABCG2 effluxes Hoechst and its expression is restricted to the most primitive human hematopoietic cells
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51. Another link between phospholipid transmembrane migration and ABC transporter gene family, inferred from a rare inherited disorder of phosphatidylserine externalization
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53. P-glycoprotein plays a drug-efflux-independent role in augmenting cell survival in acute myeloblastic leukemia and is associated with modulation of a sphin-gomyelin-ceramide apoptotic pathway
54. Evidence that ceramide mediates the ability of tumor necrosis factor to modulate primitive human hematopoietic cell fates
55. Vitamin A deficiency in mice causes a systemic expansion of myeloid cells
56. Restoration of retinoid sensitivity by MDR1 ribozymes in retinoic acid-resistant myeloid leukemic cells
57. Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells
58. Phorbol ester-induced P-glycoprotein phosphorylation and functionality in the HTB-123 human breast cancer cell line