Identification of a sex steroid-inducible gene in the neonatal rat hypothalamus

Neuroscience Letters

Volumn 242, Issue 3, 1998, Pages 127-130

  Suzuki, Masatoshi ^a   Yoshida, Shintarou ^a   Nishihara, Masugi ^a   Takahashi, Michio ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Arcuate nucleus; CDNA subtraction; Granulin; Sex steroid induced gene expression; Sexual dimorphism; Ventromedial nucleus of the hypothalamus

Indexed keywords

COMPLEMENTARY DNA; SEX HORMONE;

ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; FEMALE; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE LOCATION; HORMONAL REGULATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; THALAMUS VENTRAL NUCLEUS; VIRILIZATION;

ANIMALS; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS, HORMONAL; ARCUATE NUCLEUS; DNA, COMPLEMENTARY; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; PREGNANCY; PROTEIN PRECURSORS; RATS; RATS, WISTAR; RNA, MESSENGER; SEX CHARACTERISTICS; TESTOSTERONE; VENTROMEDIAL HYPOTHALAMIC NUCLEUS;

EID: 0032548759     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00008-1     Document Type: Article

References (20)

1. Arai Y., Matsumoto A. Synapse formation of the hypothalamic arcuate nucleus during post-natal development in the female rat and its modification by neonatal estrogen treatment. Psychoneuroendocrinology. 3:1978;31-45.
2. Arai Y., Matumoto A., Nishizuka M. Synaptogenesis and neuronal plasticity to gonadal steroids; implications for the development of sexual dimorphism in the neuroendocrine brain. Curr. Top. Neuroendocrinol. 7:1986;291-307.
3. Arnold A.P., Gorski R.A. Gonadal steroid induction of structural sex differences in the central nervous system. Annu. Rev. Neurosci. 7:1984;413-442.
4. Bateman A., Belcourt D., Bennet H., Lazure C., Solomon S. Granulins, a novel class of peptide from leukocytes. Biochem. Biophys. Res. Commun. 173:1990;1161-1168.
5. Bettini E., Maggi A. Estrogen induction of cytochrome c oxidase subunit II in rat hippocampus. J. Neurochem. 58:1992;1923-1929.
6. Bhandari V., Glaid A., Bateman A. The complementary deoxyribonucleic acid sequence, tissue distribution, and cellular localization of the rat granulin precursor. Endocrinology. 133:1993;2682-2689.
7. Cohen R.S., Pfaff D.W. Ventromedial hypothalamic neurons in the mediation of long-lasting effect of estrogen on lordosis behavior. Prog. Neurobiol. 38:1992;423-453.
8. Hsu C.Y.J., Komm B.S., Lyttle C.R., Frankel F. Cloning of estrogen-regulated messenger ribonucleic acids from rat uterus. Endocrinology. 122:1988;631-639.
9. Ikeda Y., Luo X., Abbud R., Nilson J.H., Parker K.L. The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus. Mol. Endocrinol. 9:1995;478-486.
10. MacLusky N.J., Naftolin F. Sexual differentiation of the central nervous system. Science. 211:1981;1294-1302.
11. Mastumoto A., Arai Y. Male-female difference in synaptic organization of the ventromedial nucleus of the hypothalamus in the rat. Neuroendocrinology. 42:1986;232-236.
12. McEwen B.S., Lieberburg I., Chaptal C., Krey L.C. Aromatization: important for sexual differentiation of the neonatal rat brain. Horm. Behav. 9:1977;249-263.
13. Orikasa C., Mizuno K., Sakuma Y., Hayashi S. Exogenous estrogen acts differently on production of estrogen receptor in the preoptic area and the mediobasal hypothalamus nuclei in the newborn rat. Neurosci. Res. 25:1996;247-254.
14. Salaman D.F., Birkett S. Androgen-induced sexual differentiation of the brain is blocked by inhibitors of DNA and RNA synthesis. Nature. 247:1974;109-112.
15. Sambrook, J., Fritsch, E.F. and Maniatis, T., Molecular Cloning, 2nd edn., Cold Spring Harbor Laboratory Press, New York, 1989.
16. Shoyb M., McDonald V.L., Byles C., Todaro G.J., Plowman G.D. Epithelin 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins. Proc. Natl. Acad. Sci. USA. 87:1990;7912-7916.
17. Stanley H.F., Fink G. Synthesis of specific brain proteins is influenced by testosterone at mRNA level in the neonatal rat. Brain. Res. 370:1986;223-231.
18. Stanley H.F., Borthwick N.M., Fink G. Brain protein changes during development and sexual differentiation in the rat. Brain Res. 370:1986;215-222.
19. Tanaka M., Sasaki H., Kino I., Sugimura T., Terada M. Genes preferentially expressed in embryo stomach are predominantly expressed in gastric cancer. Cancer Res. 52:1992;3372-3377.
20. Tompson C.C. Thyroid hormone-responsive genes in developing cerebellum include a novel synaptotagmin and a hairless homolog. J. Neurosci. 16:1996;7832-7840.