p56(dok-2) As a cytokine-inducible inhibitor of cell proliferation and signal transduction

EMBO Journal

Volumn 19, Issue 19, 2000, Pages 5114-5122

  Suzu, Shinya ^a   Tanaka Douzono, Miyuki ^a   Nomaguchi, Kouji ^a   Yamada, Muneo ^a   Hayasawa, Hirotoshi ^a   Kimura, Fumihiko ^b   Motoyoshi, Kazuo ^b  

^a MORINAGA MILK INDUSTRY CO LTD   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Cell proliferation; Cytokine; Dok R; FRIP; p56(dok 2)

Indexed keywords

COLONY STIMULATING FACTOR 1; CYTOKINE; DOCKING PROTEIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; PROTEIN P56; PROTEIN TYROSINE KINASE; STEM CELL FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEEDBACK SYSTEM; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; NUDE MOUSE; ONCOGENE C FOS; ONCOGENE C JUN; ONCOGENE C MYC; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 0034596997     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.19.5114     Document Type: Article

References (54)

1. Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors
2. Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src
3. Interactions of p62(dok) with p21(bcr-abl) and Bcr-Abl-associated proteins
4. Structure and expression of the hairless gene of mice
5. p62(dok): A constitutively tyrosinephosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells
6. Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1
7. Characterization of a novel member of the DOK family that binds and modulates Abl signaling
8. Src-related protein kinases in hematopoiesis
9. Activation of Src family kinases by colony-stimulating factor-1 and their association with its receptor
10. Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase
11. Suppression subtractive hybridization: A method for generating differentially regulated or tissue-specific cDNA probes and libraries
12. Molecular cloning and characterization of p56(dok-2) defines a new family of RasGAP-binding proteins
13. A new protein containing an SH2 domain that inhibits JAK kinases
14. Deregulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor in murine macrophage cell line J774A.1
15. Targeted disruption of SHIP leads to hematopoietic perturbations, lung pathology and a shortened life span
16. The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus
17. Cytokine receptor signalling
18. The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R
19. Recruitment of dok-R to the EGF receptor through its PTB domain is required for attenuation of erk MAP kinase activation
20. Structural analysis of proteoglycan macrophage colony-stimulating factor
21. Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling
22. Catalytic activity of the mouse guanine nucleotide exchanger mSOS is activated by Fyn tyrosine protein kinase and the T-cell antigen receptor in T cells
23. Shc, Grb2, Sos1 and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells
24. The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc and its induction of apoptosis
25. Independent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and Nck
26. pEF-BOS, a powerful mammalian expression vector
27. The IRS-1 signaling system
28. Tyrosine phosphorylation of Shc is mediated through Lyn and Syk in B cell receptor signaling
29. Structure and function of a new STAT-induced STAT inhibitor
30. Differentiation of the IL-3-dependent NFS-60 cell line and adaption to growth in macrophage colony-stimulating factor
31. FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation
32. Tyrosine phosphorylation of p62(dok) induced by cell adhesion and insulin: Possible role in cell migration
33. Differential ability of SOCS proteins to regulate IL-6 and CSF-1 induced macrophage differentiation
34. G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase Shc adapter protein signaling complexes
35. DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases
36. The macrophage-colony stimulating factor (M-CSF) receptor
37. A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes
38. Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling
39. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases
40. Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins
41. The c-fms proto-oncogene product is related to the receptor for the mononuclear phogocyte growth factor, CSF-1
42. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
43. A family of cytokine-inducible inhibitors of signalling
44. Biologic activity of proteoglycan macrophage colony-stimulating factor
45. Identification of alternative spliced transcripts encoding murine macrophage colony-stimulating factor
46. The RasGAP-binding protein p62(dok) is a mediator of inhibitory FcγRIIB in B cells
47. Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene
48. Identification of a ligand for the c-kit protooncogene
49. Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok
50. Role of the rasGAP-associated docking protein p62(dok) in negative regulation of B cell receptor-mediated signaling
51. Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor β chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis
52. Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epoinduced receptor tyrosine phosphorylation: Identification of potential binding sites
53. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
54. Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor