메뉴 건너뛰기




Volumn 401, Issue 6753, 1999, Pages 556-562

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 0033533891     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/44076     Document Type: Article
Times cited : (959)

References (50)
  • 1
    • 0030831130 scopus 로고    scopus 로고
    • Identification of clonogenic common lymphoid progenitors in mouse bone marrow
    • Kondo, M., Weissman, I. L. & Akashi, K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91, 661-672 (1997).
    • (1997) Cell , vol.91 , pp. 661-672
    • Kondo, M.1    Weissman, I.L.2    Akashi, K.3
  • 2
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy, R. R., Carmack, C. E., Shinton, S. A., Kemp, J. D. & Kayakawa, K. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173, 1213-1225 (1991).
    • (1991) J. Exp. Med. , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Kayakawa, K.5
  • 3
    • 0028027360 scopus 로고
    • IL-2 receptor α chain (CD25,TAC) expression defines a crucial stage in pre-B cell development
    • Rolink, A., Grawunder, U., Winkler, T. H., Karasuyama, H. & Melchers, F. IL-2 receptor α chain (CD25,TAC) expression defines a crucial stage in pre-B cell development. Int. Immunol. 6, 1257-1264 (1994).
    • (1994) Int. Immunol. , vol.6 , pp. 1257-1264
    • Rolink, A.1    Grawunder, U.2    Winkler, T.H.3    Karasuyama, H.4    Melchers, F.5
  • 4
    • 0026011211 scopus 로고
    • Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen rective B cells in vitro and in vivo
    • Rolink, A., Kudo, A., Karasuyama, H., Kikuchi, Y. & Melchers, F. Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen rective B cells in vitro and in vivo. EMBO J. 10, 327-336 (1991).
    • (1991) EMBO J. , vol.10 , pp. 327-336
    • Rolink, A.1    Kudo, A.2    Karasuyama, H.3    Kikuchi, Y.4    Melchers, F.5
  • 5
    • 0032541309 scopus 로고    scopus 로고
    • Early function of Pax5 (BSAP) prior to the pre-B cell receptor stage of B lymphopoiesis
    • Thévenin, C., Nutt, S. L. & Busslinger, M. Early function of Pax5 (BSAP) prior to the pre-B cell receptor stage of B lymphopoiesis. J. Exp. Med. 188, 735-744 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 735-744
    • Thévenin, C.1    Nutt, S.L.2    Busslinger, M.3
  • 6
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang, Y., Soriano, P. & Weintraub, H. The helix-loop-helix gene E2A is required for B cell formation. Cell 79, 875-884 (1994).
    • (1994) Cell , vol.79 , pp. 875-884
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 7
    • 0027992622 scopus 로고
    • E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
    • Bain, G. et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 79, 885-892 (1994).
    • (1994) Cell , vol.79 , pp. 885-892
    • Bain, G.1
  • 8
    • 0029045161 scopus 로고
    • Failure of B-cell differentiation in mice lacking the transcription factor EBF
    • Lin, H. & Grosschedl, R. Failure of B-cell differentiation in mice lacking the transcription factor EBF. Nature 376, 263-267 (1995).
    • (1995) Nature , vol.376 , pp. 263-267
    • Lin, H.1    Grosschedl, R.2
  • 9
    • 0030790713 scopus 로고    scopus 로고
    • EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes
    • Sigvardsson, M., O'Riordan, M. & Grosschedl, R. EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes. Immunity 7, 25-36 (1997).
    • (1997) Immunity , vol.7 , pp. 25-36
    • Sigvardsson, M.1    O'Riordan, M.2    Grosschedl, R.3
  • 10
    • 0032541471 scopus 로고    scopus 로고
    • Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12
    • Kee, B. L. & Murre, C. Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12. J. Exp. Med. 188, 699-713 (1998).
    • (1998) J. Exp. Med. , vol.188 , pp. 699-713
    • Kee, B.L.1    Murre, C.2
  • 12
    • 0026698147 scopus 로고
    • Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis
    • Adams, B. et al. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 6, 1589-1607 (1992).
    • (1992) Genes Dev. , vol.6 , pp. 1589-1607
    • Adams, B.1
  • 13
    • 0030483542 scopus 로고    scopus 로고
    • Identification of the earliest B lineage stage in mouse bone marrow
    • Li, Y.-S., Wasserman, R., Hayakawa, K. & Hardy, R. R. Identification of the earliest B lineage stage in mouse bone marrow. Immunity 5, 527-535 (1996).
    • (1996) Immunity , vol.5 , pp. 527-535
    • Li, Y.-S.1    Wasserman, R.2    Hayakawa, K.3    Hardy, R.R.4
  • 14
    • 0027997502 scopus 로고
    • Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
    • Urbánek, P., Wang, Z.-Q., Fetka, I., Wagner, E. F. & Busslinger, M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell 79, 901-912 (1994).
    • (1994) Cell , vol.79 , pp. 901-912
    • Urbánek, P.1    Wang, Z.-Q.2    Fetka, I.3    Wagner, E.F.4    Busslinger, M.5
  • 15
    • 0031038031 scopus 로고    scopus 로고
    • Essential functions of Pax5 (BSAP) in pro-B cell development: Difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus
    • Nutt, S. L., Urbánek, P., Rolink, A. & Busslinger, M. Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. Genes Dev. 11, 476-491 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 476-491
    • Nutt, S.L.1    Urbánek, P.2    Rolink, A.3    Busslinger, M.4
  • 16
    • 0032522538 scopus 로고    scopus 로고
    • Identification of BSAP (Pax-5) target genes in early B-cell development by loss- And gain-of-function experiments
    • Nutt, S. L., Morrison, A. M., Dörfler, P., Rolink, A. & Busslinger, M. Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments. EMBO J. 17, 2319-2333 (1998).
    • (1998) EMBO J. , vol.17 , pp. 2319-2333
    • Nutt, S.L.1    Morrison, A.M.2    Dörfler, P.3    Rolink, A.4    Busslinger, M.5
  • 17
    • 0026581936 scopus 로고
    • RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
    • Shinkai, Y. et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855-867 (1992).
    • (1992) Cell , vol.68 , pp. 855-867
    • Shinkai, Y.1
  • 18
    • 0030273141 scopus 로고    scopus 로고
    • The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching
    • Rolink, A., Melchers, F. & Andersson, J. The SCID but not the RAG-2 gene product is required for Sμ-Sε heavy chain class switching. Immunity 5, 319-330 (1996).
    • (1996) Immunity , vol.5 , pp. 319-330
    • Rolink, A.1    Melchers, F.2    Andersson, J.3
  • 19
    • 0030736411 scopus 로고    scopus 로고
    • Development of osteoclasts from embryonic stem cells through a pathway that is c-fms but not c-kit dependent
    • Yamane, T. et al. Development of osteoclasts from embryonic stem cells through a pathway that is c-fms but not c-kit dependent. Blood 90, 3516-3523 (1997).
    • (1997) Blood , vol.90 , pp. 3516-3523
    • Yamane, T.1
  • 20
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K. et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176, 1693-1702 (1992).
    • (1992) J. Exp. Med. , vol.176 , pp. 1693-1702
    • Inaba, K.1
  • 21
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Branchereau, J. & Steinman, R. M. Dendritic cells and the control of immunity. Nature 392, 245-252 (1998).
    • (1998) Nature , vol.392 , pp. 245-252
    • Branchereau, J.1    Steinman, R.M.2
  • 22
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymphnode organogenesis
    • Kong, Y.-Y. et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymphnode organogenesis. Nature 397, 315-323 (1999).
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.-Y.1
  • 23
    • 0030794861 scopus 로고    scopus 로고
    • Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation
    • Liu, F., Poursine-Laurent, J., Wu, H. Y. & Link, D. C. Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation. Blood 90, 2583-2590 (1997).
    • (1997) Blood , vol.90 , pp. 2583-2590
    • Liu, F.1    Poursine-Laurent, J.2    Wu, H.Y.3    Link, D.C.4
  • 24
    • 0032510062 scopus 로고    scopus 로고
    • Requirement for IRF-1 in the microenvironment supporting development of natural killer cells
    • Ogasawara, K. et al. Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 391, 700-703 (1998).
    • (1998) Nature , vol.391 , pp. 700-703
    • Ogasawara, K.1
  • 25
    • 0030049985 scopus 로고    scopus 로고
    • + cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors
    • + cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors. J. Exp. Med. 183, 187-194 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 187-194
    • Rolink, A.1
  • 26
    • 0033118750 scopus 로고    scopus 로고
    • Development and tolerance of natural killer cells
    • Raulet, D. H. Development and tolerance of natural killer cells. Curr. Opin. Immunol. 11, 129-134 (1999).
    • (1999) Curr. Opin. Immunol. , vol.11 , pp. 129-134
    • Raulet, D.H.1
  • 27
    • 0025880648 scopus 로고
    • MHC class I deficiency: Susceptibility to natural killer (NK) cells and impaired NK activity
    • Liao, N.-S., Bix, M., Zijlstra, M., Jaenisch, R. & Raulet, D. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253, 199-202 (1991).
    • (1991) Science , vol.253 , pp. 199-202
    • Liao, N.-S.1    Bix, M.2    Zijlstra, M.3    Jaenisch, R.4    Raulet, D.5
  • 28
    • 0033533822 scopus 로고    scopus 로고
    • Long-term in vivo reconstitution of T cell development by Pax5-deficient B cell progenitors
    • Rolink, A. G., Nutt, S. L., Melchers, F. & Busslinger, M. Long-term in vivo reconstitution of T cell development by Pax5-deficient B cell progenitors. Nature 401, 603-606 (1999).
    • (1999) Nature , vol.401 , pp. 603-606
    • Rolink, A.G.1    Nutt, S.L.2    Melchers, F.3    Busslinger, M.4
  • 29
    • 0027070472 scopus 로고
    • Bone and haematopoietic defects in mice lacking c-fos
    • Wang, Z.-Q. et al. Bone and haematopoietic defects in mice lacking c-fos. Nature 360, 741-745 (1992).
    • (1992) Nature , vol.360 , pp. 741-745
    • Wang, Z.-Q.1
  • 30
    • 0028173214 scopus 로고
    • C-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling
    • Grigoriadis, A. et al. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 266, 443-448 (1994).
    • (1994) Science , vol.266 , pp. 443-448
    • Grigoriadis, A.1
  • 31
    • 0030954167 scopus 로고    scopus 로고
    • Multilineage gene expression precedes commitment in the hematopoietic system
    • Hu, M. et al. Multilineage gene expression precedes commitment in the hematopoietic system. Genes Dev. 11, 774-785 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 774-785
    • Hu, M.1
  • 33
    • 0026006116 scopus 로고
    • Simultaneous occurrence of myelomonocytic leukemia and multiple myeloma: Involvement of common leukemic progenitors and their developmental abnormality of "lineage infidelity"
    • Akashi, K. et al. Simultaneous occurrence of myelomonocytic leukemia and multiple myeloma: involvement of common leukemic progenitors and their developmental abnormality of "lineage infidelity". J. Cell Physiol. 148, 446-456 (1991).
    • (1991) J. Cell Physiol. , vol.148 , pp. 446-456
    • Akashi, K.1
  • 34
    • 0023946242 scopus 로고
    • Hematopoietic lineage switch: V-raf oncogene converts Eμ-myc transgenic B cells into macrophages
    • Klinken, S. P., Alexander, W. S. & Adams, J. M. Hematopoietic lineage switch: v-raf oncogene converts Eμ-myc transgenic B cells into macrophages. Cell 53, 857-867 (1988).
    • (1988) Cell , vol.53 , pp. 857-867
    • Klinken, S.P.1    Alexander, W.S.2    Adams, J.M.3
  • 35
    • 0029739901 scopus 로고    scopus 로고
    • Progenitor tumours from Eμ-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cells survival
    • Strasser, A., Elefanty, A. G., Harris, A. W. & Cory, S. Progenitor tumours from Eμ-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cells survival. EMBO J. 15, 3823-3824 (1996).
    • (1996) EMBO J. , vol.15 , pp. 3823-3824
    • Strasser, A.1    Elefanty, A.G.2    Harris, A.W.3    Cory, S.4
  • 36
    • 0023759058 scopus 로고
    • Relationships between B cell and myeloid differentiation: Studies with a B lymphocyte progenitor line, HAFTL-1
    • Davidson, W. F., Pierce, J. H., Rudikoff, S. & Morse III, H. C. Relationships between B cell and myeloid differentiation: studies with a B lymphocyte progenitor line, HAFTL-1. J. Exp. Med. 168, 389-407 (1988).
    • (1988) J. Exp. Med. , vol.168 , pp. 389-407
    • Davidson, W.F.1    Pierce, J.H.2    Rudikoff, S.3    Morse H.C. III4
  • 37
    • 0025339731 scopus 로고
    • Transformation of murine bone marrow cells with combined v-raf-v-myc oncogenes yields clonally related mature B cells and macrophages
    • Principato, M. et al. Transformation of murine bone marrow cells with combined v-raf-v-myc oncogenes yields clonally related mature B cells and macrophages. Mol. Cell. Biol. 10, 3562-3568 (1990).
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 3562-3568
    • Principato, M.1
  • 38
    • 0025362362 scopus 로고
    • Macrophage lineage switching of murine early pre-B lymphoid cells expressing transduced fms genes
    • Borzillo, G. V., Ashmun, R. A. & Sherr, C. J. Macrophage lineage switching of murine early pre-B lymphoid cells expressing transduced fms genes. Mol. Cell. Biol. 10, 2703-2714 (1990).
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 2703-2714
    • Borzillo, G.V.1    Ashmun, R.A.2    Sherr, C.J.3
  • 39
    • 0026561448 scopus 로고
    • Bipotential precursors of B cells and macrophages in murine fetal liver
    • Cumano, A., Paige, C. J., Iscove, N. N. & Brady, G. Bipotential precursors of B cells and macrophages in murine fetal liver. Nature 356, 612-615 (1992).
    • (1992) Nature , vol.356 , pp. 612-615
    • Cumano, A.1    Paige, C.J.2    Iscove, N.N.3    Brady, G.4
  • 40
    • 0030962093 scopus 로고    scopus 로고
    • Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver
    • Kawamoto, H., Ohmura, K. & Katsura, Y. Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver. Int. Immunol. 9, 1011-1019 (1997).
    • (1997) Int. Immunol. , vol.9 , pp. 1011-1019
    • Kawamoto, H.1    Ohmura, K.2    Katsura, Y.3
  • 41
    • 0030780187 scopus 로고    scopus 로고
    • Development of natural killer cells, B lymphocytes, macrophages, and mast cells from single hematopoietic progenitors in culture of murine fetal liver cells
    • Aiba, Y. & Ogawa, M. Development of natural killer cells, B lymphocytes, macrophages, and mast cells from single hematopoietic progenitors in culture of murine fetal liver cells. Blood 90, 3923-3930 (1997).
    • (1997) Blood , vol.90 , pp. 3923-3930
    • Aiba, Y.1    Ogawa, M.2
  • 42
    • 0032425963 scopus 로고    scopus 로고
    • Identification of a fetal hematopoietic precursor with B cell, T cell, and macrophage potential
    • Lacaud, G., Carlsson, L. & Keller, G. Identification of a fetal hematopoietic precursor with B cell, T cell, and macrophage potential. Immunity 9, 827-838 (1998).
    • (1998) Immunity , vol.9 , pp. 827-838
    • Lacaud, G.1    Carlsson, L.2    Keller, G.3
  • 43
    • 0028784287 scopus 로고
    • Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset
    • Galy, A., Travis, M., Cen, D. & Chen, B. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 3, 459-473 (1995).
    • (1995) Immunity , vol.3 , pp. 459-473
    • Galy, A.1    Travis, M.2    Cen, D.3    Chen, B.4
  • 44
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • van Freeden-Jeffry, U. et al. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181, 1519-1526 (1995).
    • (1995) J. Exp. Med. , vol.181 , pp. 1519-1526
    • Van Freeden-Jeffry, U.1
  • 45
    • 0032504051 scopus 로고    scopus 로고
    • Loops, lineages, and leukemia
    • Enver, T. & Greaves, M. Loops, lineages, and leukemia. Cell 94, 9-12 (1998).
    • (1998) Cell , vol.94 , pp. 9-12
    • Enver, T.1    Greaves, M.2
  • 46
    • 0032909652 scopus 로고    scopus 로고
    • The B29 (immunoglobulin β-chain) gene is a genetic target for early B-cell factor
    • Åkerblad, P., Rosberg, M., Leanderson, T. & Sigvardsson, M. The B29 (immunoglobulin β-chain) gene is a genetic target for early B-cell factor. Mol. Cell. Biol. 19, 392-401 (1999).
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 392-401
    • Åkerblad, P.1    Rosberg, M.2    Leanderson, T.3    Sigvardsson, M.4
  • 47
    • 0032528354 scopus 로고    scopus 로고
    • Lineage commitment and maturation in hematopoietic cells: The case for extrinsic regulation
    • Metcalf, D. Lineage commitment and maturation in hematopoietic cells: the case for extrinsic regulation. Blood 92, 345-348 (1998).
    • (1998) Blood , vol.92 , pp. 345-348
    • Metcalf, D.1
  • 48
  • 49
    • 0032899415 scopus 로고    scopus 로고
    • Independent regulation of the two Pax5 alleles during B-cell development
    • Nutt, S. L. et al. Independent regulation of the two Pax5 alleles during B-cell development. Nature Genet. 21, 390-395 (1999).
    • (1999) Nature Genet. , vol.21 , pp. 390-395
    • Nutt, S.L.1
  • 50
    • 0023872192 scopus 로고
    • Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 and 5, using modified cDNA expression vectors
    • Karasuyama, H. & Melchers, F. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 and 5, using modified cDNA expression vectors. Eur. J. Immunol. 18, 97-104 (1988).
    • (1988) Eur. J. Immunol. , vol.18 , pp. 97-104
    • Karasuyama, H.1    Melchers, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.