Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation

Blood

Volumn 89, Issue 10, 1997, Pages 3636-3643

  Tsai, Fong Ying ^b   Orkin, Stuart H ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 1; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; EMBRYO; ERYTHROID CELL; HEMATOPOIESIS; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0030926190     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.10.3636.3636_3636_3643     Document Type: Article

References (36)

1. Ogawa M: Differentiation and proliferation of hematopoietic stem cells. Blood 81:2844, 1993
2. Metcalf D: Hematopoietic regulators: Redundancy or subtlety? Blood 82:3515, 1993
3. Morrison SJ, Uchida N, Weissman IL: The biology of hematopoietic stem cells. Annu Rev Cell Dev Biol 11:35, 1995
4. Orkin SH: Transcription factors and hematopoietic development. J Biol Chem 270:4955, 1995
5. Shivdasani RA, Orkin SH: The transcriptional control of hematopoiesis. Blood 87:4025, 1996
6. Orkin SH: GATA-binding transcription factors in hematopoietic cells. Blood 80:575, 1992
7. Weiss MJ, Orkin SH: GATA transcription factors: Key regulators of hematopoiesis. Exp Hematol 23:99, 1995
8. Tsai SF, Martin DI, Zon LI, D'Andrea AD, Wong GG, Orkin SH: Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature 339:446, 1989
9. Evans T, Felsenfeld G: The erythroid-specific transcription factor eryf1: A new finger protein. Cell 58:877, 1989
10. Weiss MJ, Keller G, Orkin SH: Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells. Genes Dev 8:1184, 1994
11. Fujiwara Y, Browne CP, Cunniff K, Goff S, Orkin SH: Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc Natl Acad Sci USA 93:12395, 1996
12. Landry DB, Engel JD, Sen R: Functional GATA-3 binding sites within murine CD8 alpha upstream regulatory sequences. J Exp Med 178:941, 1993
13. Ko LJ, Yamamoto M, Leonard MW, George KM, Ting P, Engel JD: Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer. Mol Cell Biol 11:2778, 1991
14. Ting C-N, Olson MC, Barton KP, Leiden JM: The GATA-3 transcription factor is required for the development of the T cell lineage. Nature 384:474, 1996
15. Dorfman DM, Wilson DB, Bruns GA, Orkin SH: Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells. J Biol Chem 267:1279, 1992
16. Visvader J, Adams JM: Megakaryocytic differentiation induced in 416B myeloid cells by GATA-2 and GATA-3 transgenes or 5-azacytidine is tightly coupled to GATA-1 expression. Blood 82:1493, 1993
17. Leonard M, Brice M, Engel JD, Papayannopoulou T: Dynamics of GATA transcription factor expression during erythroid differentiation. Blood 82:1071, 1993
18. Mouthon MA, Bernard O, Mitjavila MT, Romeo PH, Vainchenker W, Mathieu-Mahul D: Expression of tal-1 and GATA-binding proteins during human hematopoiesis. Blood 81:647, 1993
19. Tsai FY, Keller G, Kuo FC, Weiss M, Chen J, Rosenblatt M, Alt FW, Orkin SH: An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371:221, 1994
20. Keller G, Kennedy M, Papayannopoulou T, Wiles MV: Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol Cell Biol 13:473, 1993
21. Jacks T, Remington L, Williams B, Scmitt E, Halachmi S, Bronson R, Weinberg R: Tumor spectrum analysis in p53-mutant mice. Curr Biol 4:1, 1994
22. Jippo T, Mizuno H, Xu Z, Nomura S, Yamamoto M, Kitamura Y: Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: Demonstration by in situ hybridization. Blood 87:993, 1996
23. Pevny L, Lin CS, D'Agati V, Simon MC, Orkin SH, Costantini F: Development of hematopoietic cells lacking transcription factor GATA-1. Development 121:163, 1995
24. Donehower LA, Bradley A: The tumor suppressor p53. Biochem Biophys Acta 1155:181, 1993
25. Picksley SM, Lane DP: p53 and Rb: Their cellular roles. Curr Opin Cell Biol 6:853, 1994
26. Kastan MB, Canman CE, Leonard CJ: p53, cell cycle control and apoptosis: Implications for cancer. Cancer Metastasis Rev 14:3, 1995
27. Polyak K, Waldman T, He T-C, Kinzler KW, Volgelstein B: Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev 10:1945, 1996
28. Lane DP: p53, guardian of the genome. Nature 358:15, 1992
29. Greenblatt MS, Bennett WP, Hollstein M, Harris CC: Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855, 1994
30. Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery CAJ, Butel JS, Bradley A: Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356:215, 1992
31. Purdie CA, Harrison DJ, Peter A, Dobbie L, White S, Howie SEM, Salter DM, Bird CC, Wyllie AH, Hooper ML, Clarke AR: Tumour incidence, spectrum, and ploidy in mice with a large deletion in the p53 gene. Oncogene 9:603, 1994
32. Sah VP, Attardi LD, Murrigan GJ, Williams BO, Bronson RT, Jacks T: A subset of p53-deficient embryos exhibit exencephaly. Nat Genet 10:175, 1995
33. Williams GT, Smith CA, Spooncer E, Dexter TM, Taylor DR: Haemapoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 343:76, 1990
34. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M: Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by imerleukin-6. Nature 352:345, 1991
35. Metz T, Harris AW, Adams JM: Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes. Cell 82:29, 1995
36. Weiss MJ, Orkin SH: Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc Natl Acad Sci USA 92:9623, 1995