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Volumn 67, Issue 10, 2008, Pages 1382-1389

Inflammasomes and rheumatic diseases: Evolving concepts

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; DNA ANTIBODY; IMMUNOGLOBULIN G; INFLAMMASOME; INTEGRIN; INTERFERON; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LEUCINE RICH REPEAT KINASE 2; MATRIX METALLOPROTEINASE; MULTIPROTEIN COMPLEX; MYELOID DIFFERENTIATION FACTOR 88; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR PROTEIN; PATHOGEN RECOGNITION RECEPTOR; RECEPTOR PROTEIN; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RETINOIC ACID INDUCIBLE PROTEIN I; RHEUMATOID FACTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 53149123653     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2007.078014     Document Type: Review
Times cited : (65)

References (100)
  • 1
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 1989;54:1-13.
    • (1989) Cold Spring Harb Symp Quant Biol , vol.54 , pp. 1-13
    • Janeway Jr., C.A.1
  • 2
    • 0037066502 scopus 로고    scopus 로고
    • Decoding the patterns of self and nonself by the innate immune system
    • Medzhitov R, Janeway CA Jr. Decoding the patterns of self and nonself by the innate immune system. Science 2002;296:298-300.
    • (2002) Science , vol.296 , pp. 298-300
    • Medzhitov, R.1    Janeway Jr., C.A.2
  • 3
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P, The danger model: a renewed sense of self. Science 2002;296:301-5.
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 4
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Petrilli V. Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006;440:237-41.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 5
    • 22444433175 scopus 로고    scopus 로고
    • NLRs join TLRs as innate sensors of pathogens
    • Martinon F, Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol 2005;26:447-54.
    • (2005) Trends Immunol , vol.26 , pp. 447-454
    • Martinon, F.1    Tschopp, J.2
  • 7
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004;5:987-95.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 8
    • 12444341944 scopus 로고    scopus 로고
    • Toll-like receptors in innate immunity
    • Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005;17:1-14.
    • (2005) Int Immunol , vol.17 , pp. 1-14
    • Takeda, K.1    Akira, S.2
  • 12
    • 33750953650 scopus 로고    scopus 로고
    • Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: Implications for the induction and maintenance of the autoimmune process
    • Papadimitraki ED, Choulaki C, Koutala E, Bertsias G, Tsatsanis C, Gergianaki I, et al. Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum 2006;54:3601-11.
    • (2006) Arthritis Rheum , vol.54 , pp. 3601-3611
    • Papadimitraki, E.D.1    Choulaki, C.2    Koutala, E.3    Bertsias, G.4    Tsatsanis, C.5    Gergianaki, I.6
  • 13
    • 10744223444 scopus 로고    scopus 로고
    • Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: Critical role of myeloid differentiation factor 88
    • Joosten LA, Koenders Ml, Smeets RL, Heuvelmans-Jacobs M, Helsen MM, Takeda K, et al. Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88. J Immunol 2003;171:6145-53.
    • (2003) J Immunol , vol.171 , pp. 6145-6153
    • Joosten, L.A.1    Koenders, M.2    Smeets, R.L.3    Heuvelmans-Jacobs, M.4    Helsen, M.M.5    Takeda, K.6
  • 14
    • 0037333990 scopus 로고    scopus 로고
    • Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling
    • Kyburz D, Rethage J, Seibl R, Lauener R, Gay RE, Carson DA, et al. Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll-like receptor signaling. Arthritis Rheum 2003;48:642-50.
    • (2003) Arthritis Rheum , vol.48 , pp. 642-650
    • Kyburz, D.1    Rethage, J.2    Seibl, R.3    Lauener, R.4    Gay, R.E.5    Carson, D.A.6
  • 15
    • 0037312509 scopus 로고    scopus 로고
    • NALPs: A novel protein family involved in inflammation
    • Tschopp J, Martinon F, Burns K. NALPs: a novel protein family involved in inflammation. Nat Rev Mol Cell Biol 2003;4:95-104.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 95-104
    • Tschopp, J.1    Martinon, F.2    Burns, K.3
  • 18
    • 33745847180 scopus 로고    scopus 로고
    • TLRs, NLRs and RLRs: A trinity of pathogen sensors that cooperate in innate immunity
    • Creagh EM, O'Neill LA. TLRs, NLRs and RLRs: a trinity of pathogen sensors that cooperate in innate immunity. Trends Immunol 2006;27:352-7.
    • (2006) Trends Immunol , vol.27 , pp. 352-357
    • Creagh, E.M.1    O'Neill, L.A.2
  • 19
    • 0026507126 scopus 로고
    • A novel heterodimeric cysteine protease is required for interleukin-1 β processing in monocytes
    • Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, Kostura MJ, et al. A novel heterodimeric cysteine protease is required for interleukin-1 β processing in monocytes. Nature 1992;356:768-74.
    • (1992) Nature , vol.356 , pp. 768-774
    • Thornberry, N.A.1    Bull, H.G.2    Calaycay, J.R.3    Chapman, K.T.4    Howard, A.D.5    Kostura, M.J.6
  • 21
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
    • Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanahan TK, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005;23:479-90.
    • (2005) Immunity , vol.23 , pp. 479-490
    • Schmitz, J.1    Owyang, A.2    Oldham, E.3    Song, Y.4    Murphy, E.5    McClanahan, T.K.6
  • 22
    • 0035884195 scopus 로고    scopus 로고
    • Targeting of the transcription factor Max during apoptosis: Phosphorylationregulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1
    • Krippner-Heidenreich A, Talanian RV, Sekul R, Kraft R, Thole H, Ottleben H, et al. Targeting of the transcription factor Max during apoptosis: phosphorylationregulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1. Biochem J 2001;358:705-15.
    • (2001) Biochem J , vol.358 , pp. 705-715
    • Krippner-Heidenreich, A.1    Talanian, R.V.2    Sekul, R.3    Kraft, R.4    Thole, H.5    Ottleben, H.6
  • 23
    • 0344417114 scopus 로고    scopus 로고
    • Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype
    • Schwartz S Jr, Yamamoto H, Navarro M, Maestro M, Reventos J, Perucho M. Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype. Cancer Res 1999;59:2995-3002.
    • (1999) Cancer Res , vol.59 , pp. 2995-3002
    • Schwartz Jr, S.1    Yamamoto, H.2    Navarro, M.3    Maestro, M.4    Reventos, J.5    Perucho, M.6
  • 24
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of prolL-β
    • Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of prolL-β Mol Cell 2002;10:417-26.
    • (2002) Mol Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 25
    • 2542457495 scopus 로고    scopus 로고
    • Inflammatory caspases: Linking an intracellular innate immune system to autoinflammatory diseases
    • Martinon F, Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases. Cell 2004;117:561-74.
    • (2004) Cell , vol.117 , pp. 561-574
    • Martinon, F.1    Tschopp, J.2
  • 26
    • 0037155687 scopus 로고    scopus 로고
    • RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis
    • Mackey D, Holt BF III, Wiig A, Dangl JL. RIN4 interacts with Pseudomonas syringae type III effector molecules and is required for RPM1-mediated resistance in Arabidopsis. Cell 2002;108:743-54.
    • (2002) Cell , vol.108 , pp. 743-754
    • Mackey, D.1    Holt III, B.F.2    Wiig, A.3    Dangl, J.L.4
  • 27
    • 0037423306 scopus 로고    scopus 로고
    • Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance
    • Mackey D, Belkhadir Y, Alonso JM, Ecker JR, Dangl JL. Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance. Cell 2003;112:379-89.
    • (2003) Cell , vol.112 , pp. 379-389
    • Mackey, D.1    Belkhadir, Y.2    Alonso, J.M.3    Ecker, J.R.4    Dangl, J.L.5
  • 28
    • 34247574122 scopus 로고    scopus 로고
    • Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
    • Kummer JA, Broekhuizen R, Everett H, Agostini L, Kuijk L, Martinon F, et al. Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem 2007;55:443-52.
    • (2007) J Histochem Cytochem , vol.55 , pp. 443-452
    • Kummer, J.A.1    Broekhuizen, R.2    Everett, H.3    Agostini, L.4    Kuijk, L.5    Martinon, F.6
  • 29
    • 33845497181 scopus 로고    scopus 로고
    • Inflammatory caspases and inflammasomes: Master switches of inflammation
    • Martinon F, Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ 2007;14:10-22.
    • (2007) Cell Death Differ , vol.14 , pp. 10-22
    • Martinon, F.1    Tschopp, J.2
  • 31
    • 0035860780 scopus 로고    scopus 로고
    • Lee SH, Stehlik C, Reed JC. Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing. J Biol Chem 2001;276:34495-500.
    • Lee SH, Stehlik C, Reed JC. Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing. J Biol Chem 2001;276:34495-500.
  • 32
    • 0034743434 scopus 로고    scopus 로고
    • Regulation of IL-1 β generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins
    • Druilhe A, Srinivasula SM, Razmara M, Ahmad M, Alnemri ES. Regulation of IL-1 β generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins. Cell Death Differ 2001;8:649-57.
    • (2001) Cell Death Differ , vol.8 , pp. 649-657
    • Druilhe, A.1    Srinivasula, S.M.2    Razmara, M.3    Ahmad, M.4    Alnemri, E.S.5
  • 33
    • 10644270650 scopus 로고    scopus 로고
    • INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1 β generation
    • Lamkanfi M, Denecker G, Kalai M, D'hondt K, Meeus A, Declercq W, et al. INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1 β generation. J Biol Chem 2004;279:51729-38.
    • (2004) J Biol Chem , vol.279 , pp. 51729-51738
    • Lamkanfi, M.1    Denecker, G.2    Kalai, M.3    D'hondt, K.4    Meeus, A.5    Declercq, W.6
  • 34
    • 28844466449 scopus 로고    scopus 로고
    • Johnston JB, Barrett JW, Nazarian SH. Goodwin M, Ricuttk 0, Wang G. et al. A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection. Immunity 2005;23:587-98.
    • Johnston JB, Barrett JW, Nazarian SH. Goodwin M, Ricuttk) 0, Wang G. et al. A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection. Immunity 2005;23:587-98.
  • 35
    • 3142654767 scopus 로고    scopus 로고
    • Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
    • Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, et al. Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf Nature 2004;430:213-18.
    • (2004) Nature , vol.430 , pp. 213-218
    • Mariathasan, S.1    Newton, K.2    Monack, D.M.3    Vucic, D.4    French, D.M.5    Lee, W.P.6
  • 36
    • 33748598700 scopus 로고    scopus 로고
    • Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
    • Gurcel L, Abrami L, Girardin S, Tschopp J, van der Goot FG. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 2006;126:1135-45.
    • (2006) Cell , vol.126 , pp. 1135-1145
    • Gurcel, L.1    Abrami, L.2    Girardin, S.3    Tschopp, J.4    van der Goot, F.G.5
  • 38
    • 33744464740 scopus 로고    scopus 로고
    • Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages
    • Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages. Nat Immunol 2006;7:576-82.
    • (2006) Nat Immunol , vol.7 , pp. 576-582
    • Franchi, L.1    Amer, A.2    Body-Malapel, M.3    Kanneganti, T.D.4    Ozoren, N.5    Jagirdar, R.6
  • 39
    • 32944462834 scopus 로고    scopus 로고
    • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
    • Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 2006;440:233-6.
    • (2006) Nature , vol.440 , pp. 233-236
    • Kanneganti, T.D.1    Ozoren, N.2    Body-Malapel, M.3    Amer, A.4    Park, J.H.5    Franchi, L.6
  • 40
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-13-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-13-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004;20:319-25.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 42
    • 0027276419 scopus 로고
    • An essential role for Langerhans cellderived IL-Iβ in the initiation of primary immune responses in skin
    • Enk AH, Angeloni VL, Udey MC, Katz SI. An essential role for Langerhans cellderived IL-Iβ in the initiation of primary immune responses in skin. J Immunol 1993;150:3698-704.
    • (1993) J Immunol , vol.150 , pp. 3698-3704
    • Enk, A.H.1    Angeloni, V.L.2    Udey, M.C.3    Katz, S.I.4
  • 43
    • 0035869399 scopus 로고    scopus 로고
    • Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice
    • Antonopoulos C, Cumberbatch M, Dearman RJ, Daniel RJ, Kimber I, Groves RW. Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice. J Immunol 2001;166:3672-7.
    • (2001) J Immunol , vol.166 , pp. 3672-3677
    • Antonopoulos, C.1    Cumberbatch, M.2    Dearman, R.J.3    Daniel, R.J.4    Kimber, I.5    Groves, R.W.6
  • 44
    • 33644985564 scopus 로고    scopus 로고
    • Critical role for NALP3/CIASI/cryopyrin in innate and adaptive immunity through its regulation of caspase-1
    • Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, et al. Critical role for NALP3/CIASI/cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 2006;24:317-27.
    • (2006) Immunity , vol.24 , pp. 317-327
    • Sutterwala, F.S.1    Ogura, Y.2    Szczepanik, M.3    Lara-Tejero, M.4    Lichtenberger, G.S.5    Grant, E.P.6
  • 45
  • 46
    • 0020586432 scopus 로고
    • The adjuvanticity of interleukin 1 in vivo
    • Staruch MJ, Wood DD. The adjuvanticity of interleukin 1 in vivo. J Immunol 1983;130:2191-4.
    • (1983) J Immunol , vol.130 , pp. 2191-2194
    • Staruch, M.J.1    Wood, D.D.2
  • 47
    • 34247106805 scopus 로고    scopus 로고
    • Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1β and IL-18 release
    • Li H, Nookala S, Re F. Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1β and IL-18 release. J Immunol 2007;178:5271-6.
    • (2007) J Immunol , vol.178 , pp. 5271-5276
    • Li, H.1    Nookala, S.2    Re, F.3
  • 48
    • 34249044447 scopus 로고    scopus 로고
    • Type I interferon signaling is required for activation of the inflammasome during Francisella infection
    • Henry T, Brotcke A, Weiss DS, Thompson LJ, Monack DM. Type I interferon signaling is required for activation of the inflammasome during Francisella infection. J Exp Med 2007;204:987-94.
    • (2007) J Exp Med , vol.204 , pp. 987-994
    • Henry, T.1    Brotcke, A.2    Weiss, D.S.3    Thompson, L.J.4    Monack, D.M.5
  • 51
    • 0035097986 scopus 로고    scopus 로고
    • Increased production of intracellular interleukin-1 receptor antagonist type I in the synovium of mice with collagen-induced arthritis: A possible role in the resolution of arthritis
    • Gabay C, Marinova-Mutafchieva L, Williams RO, Gigley JP. Butler DM, Feldmann M, et al. Increased production of intracellular interleukin-1 receptor antagonist type I in the synovium of mice with collagen-induced arthritis: a possible role in the resolution of arthritis. Arthritis Rheum 2001;44:451-62.
    • (2001) Arthritis Rheum , vol.44 , pp. 451-462
    • Gabay, C.1    Marinova-Mutafchieva, L.2    Williams, R.O.3    Gigley, J.P.4    Butler, D.M.5    Feldmann, M.6
  • 52
    • 0031253812 scopus 로고    scopus 로고
    • Constitutive intra-articular expression of human IL-1β following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis
    • Ghivizzani SC, Kang R, Georgescu HI, Lechman ER, Jaffurs D, Engle JM, et al. Constitutive intra-articular expression of human IL-1β following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. J Immunol 1997;159:3604-12.
    • (1997) J Immunol , vol.159 , pp. 3604-3612
    • Ghivizzani, S.C.1    Kang, R.2    Georgescu, H.I.3    Lechman, E.R.4    Jaffurs, D.5    Engle, J.M.6
  • 53
    • 0034130274 scopus 로고    scopus 로고
    • Interindividual and intra-articular variation of proinflammatory cytokines in patients with rheumatoid arthritis: Potential implications for treatment
    • Ulfgren AK, Grondal L, Lindblad S, Khademi M, Johnell 0, Klareskog L, et al. Interindividual and intra-articular variation of proinflammatory cytokines in patients with rheumatoid arthritis: potential implications for treatment. Ann Rheum Dis 2000;59:439-47.
    • (2000) Ann Rheum Dis , vol.59 , pp. 439-447
    • Ulfgren, A.K.1    Grondal, L.2    Lindblad, S.3    Khademi, M.4    Johnell 05    Klareskog, L.6
  • 55
    • 0035108083 scopus 로고    scopus 로고
    • Lymphocytes induce monocyte chemoattractant protein-1 production by renal cells after Fcγ receptor cross-linking: Role of IL-1β
    • Rovin BH, Lu L, Marsh CB. Lymphocytes induce monocyte chemoattractant protein-1 production by renal cells after Fcγ receptor cross-linking: role of IL-1β. J Leukoc Biol 2001;69:435-9.
    • (2001) J Leukoc Biol , vol.69 , pp. 435-439
    • Rovin, B.H.1    Lu, L.2    Marsh, C.B.3
  • 56
    • 0037415555 scopus 로고    scopus 로고
    • Activation of dendritic cells through the interleukin 1 receptor 1 is critical for the induction of autoimmune myocarditis
    • Eriksson U, Kurrer MO, Sonderegger I, lezzi G, Tafuri A, Hunziker L, et al. Activation of dendritic cells through the interleukin 1 receptor 1 is critical for the induction of autoimmune myocarditis. J Exp Med 2003;197:323-31.
    • (2003) J Exp Med , vol.197 , pp. 323-331
    • Eriksson, U.1    Kurrer, M.O.2    Sonderegger, I.3    lezzi, G.4    Tafuri, A.5    Hunziker, L.6
  • 57
    • 0035399950 scopus 로고    scopus 로고
    • IL-1 enhances T celldependent antibody production through induction of CD40 ligand and 0×40 on T cells
    • Nakae S, Asano M, Horai R, Sakaguchi N, Iwakura Y. IL-1 enhances T celldependent antibody production through induction of CD40 ligand and 0×40 on T cells. J Immunol 2001;167:90-7.
    • (2001) J Immunol , vol.167 , pp. 90-97
    • Nakae, S.1    Asano, M.2    Horai, R.3    Sakaguchi, N.4    Iwakura, Y.5
  • 59
    • 0030777296 scopus 로고    scopus 로고
    • Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2
    • Rothe H, Jenkins NA, Copeland NG, Kolb H. Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. J Clin Invest 1997;99:469-74.
    • (1997) J Clin Invest , vol.99 , pp. 469-474
    • Rothe, H.1    Jenkins, N.A.2    Copeland, N.G.3    Kolb, H.4
  • 60
    • 0034659770 scopus 로고    scopus 로고
    • Combined effects of IL-12 and IL-18 on the induction of collagen-induced arthritis
    • Leung BP, Mclnnes IB. Esfandiari E, Wei XQ, Liew FY. Combined effects of IL-12 and IL-18 on the induction of collagen-induced arthritis. J Immunol 2000;164:6495-502.
    • (2000) J Immunol , vol.164 , pp. 6495-6502
    • Leung, B.P.1    Mclnnes, I.B.2    Esfandiari, E.3    Wei, X.Q.4    Liew, F.Y.5
  • 61
    • 0035173776 scopus 로고    scopus 로고
    • Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18
    • Wei XQ, Leung BP. Arthur HM, Mclnnes IB. Liew FY. Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18 J Immunol 2001;166:517-21.
    • (2001) J Immunol , vol.166 , pp. 517-521
    • Wei, X.Q.1    Leung, B.P.2    Arthur, H.M.3    Mclnnes, I.B.4    Liew, F.Y.5
  • 63
    • 0033152023 scopus 로고    scopus 로고
    • IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: Expression and localization in intestinal mucosal cells
    • Pizarro TT, Michie MH, Bentz M. Woraratanadharm J, Smith MF Jr, Foley E. et al. IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn's disease: expression and localization in intestinal mucosal cells. J Immunol 1999;162:6829-35.
    • (1999) J Immunol , vol.162 , pp. 6829-6835
    • Pizarro, T.T.1    Michie, M.H.2    Bentz, M.3    Woraratanadharm, J.4    Smith Jr, M.F.5    Foley, E.6
  • 66
    • 0034909059 scopus 로고    scopus 로고
    • Mature form of interleukin 18 is expressed in rheumatoid arthritis synovial tissue and contributes to interferon-γ production by synovial T cells
    • Tanaka M, Harigai M, Kawaguchi Y, Ohta S, Sugiura T, Takagi K. et al. Mature form of interleukin 18 is expressed in rheumatoid arthritis synovial tissue and contributes to interferon-γ production by synovial T cells. J Rheumatol 2001;28:1779-87.
    • (2001) J Rheumatol , vol.28 , pp. 1779-1787
    • Tanaka, M.1    Harigai, M.2    Kawaguchi, Y.3    Ohta, S.4    Sugiura, T.5    Takagi, K.6
  • 67
    • 0033515520 scopus 로고    scopus 로고
    • Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
    • McDermott MF, Aksentijevich I, Galon J, McDermott EM, Ogunkolade BW, Centola M. et al. Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. Cell 1999;97:133-44.
    • (1999) Cell , vol.97 , pp. 133-144
    • McDermott, M.F.1    Aksentijevich, I.2    Galon, J.3    McDermott, E.M.4    Ogunkolade, B.W.5    Centola, M.6
  • 68
    • 0037349294 scopus 로고    scopus 로고
    • Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
    • Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, et al. Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol Cell 2003;11:591-604.
    • (2003) Mol Cell , vol.11 , pp. 591-604
    • Chae, J.J.1    Komarow, H.D.2    Cheng, J.3    Wood, G.4    Raben, N.5    Liu, P.P.6
  • 69
    • 33745631232 scopus 로고    scopus 로고
    • The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1 p production
    • Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ. et al. The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1 p production. Proc Natl Acad Sci USA 2006;103:9982-7.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9982-9987
    • Chae, J.J.1    Wood, G.2    Masters, S.L.3    Richard, K.4    Park, G.5    Smith, B.J.6
  • 70
    • 30844432876 scopus 로고    scopus 로고
    • Cryopyrin and pyrin activate caspase-1, but not NF-kκB, via ASC oligomerization
    • Yu JW, Wu J, Zhang Z, Datta P, Ibrahimi I, Taniguchi S, et al. Cryopyrin and pyrin activate caspase-1, but not NF-kκB, via ASC oligomerization. Cell Death Differ 2006;13:236-49.
    • (2006) Cell Death Differ , vol.13 , pp. 236-249
    • Yu, J.W.1    Wu, J.2    Zhang, Z.3    Datta, P.4    Ibrahimi, I.5    Taniguchi, S.6
  • 71
    • 34547138176 scopus 로고    scopus 로고
    • The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits prolL-1β processing
    • Papin S, Cuenin S, Agostini L, Martinon F, Werner S, Beer HD. et al. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits prolL-1β processing. Cell Death Differ 2007;14:1457-66.
    • (2007) Cell Death Differ , vol.14 , pp. 1457-1466
    • Papin, S.1    Cuenin, S.2    Agostini, L.3    Martinon, F.4    Werner, S.5    Beer, H.D.6
  • 72
    • 41849105723 scopus 로고    scopus 로고
    • The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever
    • Calligaris L, Marchetti F, Tommasini A, Ventura A. The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever. Eur J Pediatr 2008;167:695-6
    • (2008) Eur J Pediatr , vol.167 , pp. 695-696
    • Calligaris, L.1    Marchetti, F.2    Tommasini, A.3    Ventura, A.4
  • 73
    • 27344448749 scopus 로고    scopus 로고
    • Familial autoinflammatory diseases: Genetics, pathogenesis and treatment
    • Stojanov S, Kastner DL. Familial autoinflammatory diseases: genetics, pathogenesis and treatment. Curr Opin Rheumatol 2005;17:586-599
    • (2005) Curr Opin Rheumatol , vol.17 , pp. 586-599
    • Stojanov, S.1    Kastner, D.L.2
  • 74
    • 0035179970 scopus 로고    scopus 로고
    • Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
    • Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001;29:301-5.
    • (2001) Nat Genet , vol.29 , pp. 301-305
    • Hoffman, H.M.1    Mueller, J.L.2    Broide, D.H.3    Wanderer, A.A.4    Kolodner, R.D.5
  • 75
    • 0036745064 scopus 로고    scopus 로고
    • Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis
    • Aganna E, Martinon F, Hawkins PN, Ross JB, Swan DC, Booth DR, et al. Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum, 2002;46:2445-52.
    • (2002) Arthritis Rheum , vol.46 , pp. 2445-2452
    • Aganna, E.1    Martinon, F.2    Hawkins, P.N.3    Ross, J.B.4    Swan, D.C.5    Booth, D.R.6
  • 76
    • 10444241090 scopus 로고    scopus 로고
    • Clinical and genetic heterogeneity among Spanish patients with recurrent autoinflammatory syndromes associated with the CIAS1/PYPAF1/NALP3 gene
    • Arostegui Jl, Aldea A, Modesto C, Rua MJ. Arguelles F. Gonzalez-Ensenat MA. et al. Clinical and genetic heterogeneity among Spanish patients with recurrent autoinflammatory syndromes associated with the CIAS1/PYPAF1/NALP3 gene. Arthritis Rheum 2004;50:4045-50.
    • (2004) Arthritis Rheum , vol.50 , pp. 4045-4050
    • Arostegui, J.1    Aldea, A.2    Modesto, C.3    Rua, M.J.4    Arguelles, F.5    Gonzalez-Ensenat, M.A.6
  • 77
    • 0037792866 scopus 로고    scopus 로고
    • Interleukin-1-receptor antagonist in the Muckle-Wells syndrome
    • Hawkins PN, Lachmann HJ, McDermott MF. Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N Engl J Med 2003;348:2583-4.
    • (2003) N Engl J Med , vol.348 , pp. 2583-2584
    • Hawkins, P.N.1    Lachmann, H.J.2    McDermott, M.F.3
  • 78
    • 8444225132 scopus 로고    scopus 로고
    • Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
    • Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, et al. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 2004;364:1779-85.
    • (2004) Lancet , vol.364 , pp. 1779-1785
    • Hoffman, H.M.1    Rosengren, S.2    Boyle, D.L.3    Cho, J.Y.4    Nayar, J.5    Mueller, J.L.6
  • 79
  • 80
    • 33746747096 scopus 로고    scopus 로고
    • MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
    • Chen CJ, Shi Y, Hearn A, Fitzgerald K, Golenbock D, Reed G, et al. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest 2006;116:2262-71.
    • (2006) J Clin Invest , vol.116 , pp. 2262-2271
    • Chen, C.J.1    Shi, Y.2    Hearn, A.3    Fitzgerald, K.4    Golenbock, D.5    Reed, G.6
  • 82
    • 18644385243 scopus 로고    scopus 로고
    • Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
    • Pascual V, Allantaz F, Arce E, Punaro M, Banchereau J. Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J Exp Med 2005;201:1479-86
    • (2005) J Exp Med , vol.201 , pp. 1479-1486
    • Pascual, V.1    Allantaz, F.2    Arce, E.3    Punaro, M.4    Banchereau, J.5
  • 83
  • 86
    • 7944232105 scopus 로고    scopus 로고
    • Identification of bacterial as activator of the NALP3/cryopyrin inflammasonne
    • Martinon F, Agostinil Meylan E. Tschopp J. Identification of bacterial as activator of the NALP3/cryopyrin inflammasonne. Curr Biol 2004;14:1929-34.
    • (2004) Curr Biol , vol.14 , pp. 1929-1934
    • Martinon, F.1    Agostinil Meylan, E.2    Tschopp, J.3
  • 87
    • 33846014297 scopus 로고    scopus 로고
    • Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
    • Kannganti TD, Body-Malapel M. Amer A. Park JH, Whitfield J, Franchi L. et al. Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J Biol Chem 2006;281:36560-8.
    • (2006) J Biol Chem , vol.281 , pp. 36560-36568
    • Kannganti, T.D.1    Body-Malapel, M.2    Amer, A.3    Park, J.H.4    Whitfield, J.5    Franchi, L.6
  • 88
    • 34548027736 scopus 로고    scopus 로고
    • Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
    • Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 2007;14:1583-9.
    • (2007) Cell Death Differ , vol.14 , pp. 1583-1589
    • Petrilli, V.1    Papin, S.2    Dostert, C.3    Mayor, A.4    Martinon, F.5    Tschopp, J.6
  • 89
    • 34250835251 scopus 로고    scopus 로고
    • The inflammasome mediates UVB-induced activation and secretion of interleukin-1β by keratinocytes
    • Feldmeyer L, Keller M, Niklaus G, Hohl D, Werner S, Beer HD. The inflammasome mediates UVB-induced activation and secretion of interleukin-1β by keratinocytes. Curr Biol 2007;17:1140-5.
    • (2007) Curr Biol , vol.17 , pp. 1140-1145
    • Feldmeyer, L.1    Keller, M.2    Niklaus, G.3    Hohl, D.4    Werner, S.5    Beer, H.D.6
  • 91
    • 33846024748 scopus 로고    scopus 로고
    • Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
    • Amer A, Franchi L, Kanneganti TD, Body-Malapel M, Ozoren N, Brady G, et al. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. J Biol Chem 2006;281:35217-23.
    • (2006) J Biol Chem , vol.281 , pp. 35217-35223
    • Amer, A.1    Franchi, L.2    Kanneganti, T.D.3    Body-Malapel, M.4    Ozoren, N.5    Brady, G.6
  • 92
    • 31744441475 scopus 로고    scopus 로고
    • Nalp 1b controls mouse macrophage susceptibility to anthrax lethal toxin
    • Boyden ED, Dietrich WF. Nalp 1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 2006;38:240-4.
    • (2006) Nat Genet , vol.38 , pp. 240-244
    • Boyden, E.D.1    Dietrich, W.F.2
  • 93
    • 5044223401 scopus 로고    scopus 로고
    • Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis
    • Verbsky JW, White AJ. Effective use of the recombinant interleukin 1 receptor antagonist anakinra in therapy resistant systemic onset juvenile rheumatoid arthritis. J Rheumatol 2004;31:2071-5.
    • (2004) J Rheumatol , vol.31 , pp. 2071-2075
    • Verbsky, J.W.1    White, A.J.2
  • 94
    • 16944365196 scopus 로고    scopus 로고
    • A candidate gene for familial Mediterranean fever
    • The French FMF Consortium
    • The French FMF Consortium. A candidate gene for familial Mediterranean fever. Nat Genet 1997;17:25-31.
    • (1997) Nat Genet , vol.17 , pp. 25-31
  • 95
    • 0030745449 scopus 로고    scopus 로고
    • Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever
    • The International FMF Consortium
    • The International FMF Consortium. Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. Cell 1997;90:797-807.
    • (1997) Cell , vol.90 , pp. 797-807
  • 96
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001;411:599-603.
    • (2001) Nature , vol.411 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3    Lesage, S.4    Cezard, J.P.5    Belaiche, J.6
  • 97
    • 0035978533 scopus 로고    scopus 로고
    • Aframeshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N, Nicolae DL. Chen FF, Ramos R, et al. Aframeshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001;411:603-6.
    • (2001) Nature , vol.411 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3    Nicolae, D.L.4    Chen, F.F.5    Ramos, R.6
  • 98
    • 34248136828 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Cause and immunobiology
    • Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet 2007;369:1627-40.
    • (2007) Lancet , vol.369 , pp. 1627-1640
    • Baumgart, D.C.1    Carding, S.R.2
  • 99
    • 0033215040 scopus 로고    scopus 로고
    • Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
    • Deveraux QL, Leo E, Stennicke HR, Welsh K, Salvesen GS, Reed JC. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases. EMBO J 1999;18:5242-51.
    • (1999) EMBO J , vol.18 , pp. 5242-5251
    • Deveraux, Q.L.1    Leo, E.2    Stennicke, H.R.3    Welsh, K.4    Salvesen, G.S.5    Reed, J.C.6
  • 100
    • 33845890803 scopus 로고    scopus 로고
    • Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation
    • Mariathasan S, Monack DM. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat Rev Immunol 2007;7:31-40.
    • (2007) Nat Rev Immunol , vol.7 , pp. 31-40
    • Mariathasan, S.1    Monack, D.M.2


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