-
1
-
-
14944364661
-
Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen
-
Adachi Y., Suzuki H., Schinkel A.H., and Sugiyama Y. Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen. Mol. Pharmacol. 67 (2005) 923-928
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 923-928
-
-
Adachi, Y.1
Suzuki, H.2
Schinkel, A.H.3
Sugiyama, Y.4
-
2
-
-
0042125510
-
Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro
-
Adachi Y., Suzuki H., and Sugiyama Y. Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro. Pharm. Res. 20 (2003) 1163-1169
-
(2003)
Pharm. Res.
, vol.20
, pp. 1163-1169
-
-
Adachi, Y.1
Suzuki, H.2
Sugiyama, Y.3
-
3
-
-
0033199027
-
The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin
-
Allen J.D., Brinkhuis R.F., Wijnholds J., and Schinkel A.H. The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin. Cancer Res. 59 (1999) 4237-4241
-
(1999)
Cancer Res.
, vol.59
, pp. 4237-4241
-
-
Allen, J.D.1
Brinkhuis, R.F.2
Wijnholds, J.3
Schinkel, A.H.4
-
4
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
Allikmets R., Schriml L.M., Hutchinson A., Romano-Spica V., and Dean M. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res. 58 (1998) 5337-5339
-
(1998)
Cancer Res.
, vol.58
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
5
-
-
0014471251
-
Multiplicity of hepatic excretory mechanisms for organic anions
-
Alpert S., Mosher M., Shanske A., and Arias I.M. Multiplicity of hepatic excretory mechanisms for organic anions. J. Gen. Physiol. 53 (1969) 238-247
-
(1969)
J. Gen. Physiol.
, vol.53
, pp. 238-247
-
-
Alpert, S.1
Mosher, M.2
Shanske, A.3
Arias, I.M.4
-
6
-
-
42949154087
-
-
Alvarez, A.I., Perez, M., Prieto, J.G., Molina, A.J., Real, R., Merino, G., in press. Fluoroquinolone efflux mediated by ABC transporters. J. Pharm. Sci. doi:10.1002/jps.21233.
-
Alvarez, A.I., Perez, M., Prieto, J.G., Molina, A.J., Real, R., Merino, G., in press. Fluoroquinolone efflux mediated by ABC transporters. J. Pharm. Sci. doi:10.1002/jps.21233.
-
-
-
-
7
-
-
0033062432
-
Macrolide antibiotics, drug interactions and microsomal enzymes: implications for veterinary medicine
-
Anadon A., and Reeve-johnson L. Macrolide antibiotics, drug interactions and microsomal enzymes: implications for veterinary medicine. Res. Vet. Sci. 66 (1999) 197-203
-
(1999)
Res. Vet. Sci.
, vol.66
, pp. 197-203
-
-
Anadon, A.1
Reeve-johnson, L.2
-
8
-
-
35148834736
-
Drug-drug interactions affected by the transporter protein, P-glycoprotein (ABCB1, MDR1) II. Clinical aspects
-
Aszalos A. Drug-drug interactions affected by the transporter protein, P-glycoprotein (ABCB1, MDR1) II. Clinical aspects. Drug Discov. Today 12 (2007) 838-843
-
(2007)
Drug Discov. Today
, vol.12
, pp. 838-843
-
-
Aszalos, A.1
-
9
-
-
33646798056
-
Comparison of drug efflux transport kinetics in various blood-brain barrier models
-
Bachmeier C.J., Trickler W.J., and Miller D.W. Comparison of drug efflux transport kinetics in various blood-brain barrier models. Drug Metab. Dispos. 34 (2006) 998-1003
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 998-1003
-
-
Bachmeier, C.J.1
Trickler, W.J.2
Miller, D.W.3
-
10
-
-
0031773482
-
In vitro and in vivo reversal of cancer cell multidrug resistance by the semi-synthetic antibiotic tiamulin
-
Baggetto L.G., Dong M., Bernaud J., Espinosa L., Rigal D., Bonvallet R., and Marthinet E. In vitro and in vivo reversal of cancer cell multidrug resistance by the semi-synthetic antibiotic tiamulin. Biochem. Pharmacol. 56 (1998) 1219-1228
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 1219-1228
-
-
Baggetto, L.G.1
Dong, M.2
Bernaud, J.3
Espinosa, L.4
Rigal, D.5
Bonvallet, R.6
Marthinet, E.7
-
11
-
-
33846271368
-
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein
-
Baltes S., Gastens A.M., Fedrowitz M., Potschka H., Kaever V., and Loscher W. Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein. Neuropharmacology 52 (2007) 333-346
-
(2007)
Neuropharmacology
, vol.52
, pp. 333-346
-
-
Baltes, S.1
Gastens, A.M.2
Fedrowitz, M.3
Potschka, H.4
Kaever, V.5
Loscher, W.6
-
12
-
-
0042626552
-
Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system
-
Bauer B., Miller D.S., and Fricker G. Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system. Pharm. Res. 20 (2003) 1170-1176
-
(2003)
Pharm. Res.
, vol.20
, pp. 1170-1176
-
-
Bauer, B.1
Miller, D.S.2
Fricker, G.3
-
13
-
-
0034705870
-
Selamectin: a novel broad-spectrum endectocide for dogs and cats
-
Bishop B.F., Bruce C.I., Evans N.A., Goudie A.C., Gration K.A., Gibson S.P., Pacey M.S., Perry D.A., Walshe N.D., and Witty M.J. Selamectin: a novel broad-spectrum endectocide for dogs and cats. Vet. Parasitol. 91 (2000) 163-176
-
(2000)
Vet. Parasitol.
, vol.91
, pp. 163-176
-
-
Bishop, B.F.1
Bruce, C.I.2
Evans, N.A.3
Goudie, A.C.4
Gration, K.A.5
Gibson, S.P.6
Pacey, M.S.7
Perry, D.A.8
Walshe, N.D.9
Witty, M.J.10
-
15
-
-
0036074018
-
Mammalian ABC transporters in health and disease
-
Borst P., and Elferink R.O. Mammalian ABC transporters in health and disease. Annu. Rev. Biochem. 71 (2002) 537-592
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 537-592
-
-
Borst, P.1
Elferink, R.O.2
-
16
-
-
37349020802
-
Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers
-
Brayden D.J., and Griffin J. Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers. Vet. Res. Commun. 32 (2008) 93-106
-
(2008)
Vet. Res. Commun.
, vol.32
, pp. 93-106
-
-
Brayden, D.J.1
Griffin, J.2
-
17
-
-
0040761368
-
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
-
Buchler M., Konig J., Brom M., Kartenbeck J., Spring H., Horie T., and Keppler D. cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J. Biol. Chem. 271 (1996) 15091-15098
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15091-15098
-
-
Buchler, M.1
Konig, J.2
Brom, M.3
Kartenbeck, J.4
Spring, H.5
Horie, T.6
Keppler, D.7
-
18
-
-
34548125396
-
Factors impacting the expression of membrane-bound proteins in lymphocytes from HIV-positive subjects
-
Chandler B., Detsika M., Khoo S.H., Williams J., Back D.J., and Owen A. Factors impacting the expression of membrane-bound proteins in lymphocytes from HIV-positive subjects. J. Antimicrob. Chemother. 60 (2007) 685-689
-
(2007)
J. Antimicrob. Chemother.
, vol.60
, pp. 685-689
-
-
Chandler, B.1
Detsika, M.2
Khoo, S.H.3
Williams, J.4
Back, D.J.5
Owen, A.6
-
19
-
-
3542995726
-
The complexities of hepatic drug transport: current knowledge and emerging concepts
-
Chandra P., and Brouwer K.L.R. The complexities of hepatic drug transport: current knowledge and emerging concepts. Pharm. Res. 21 (2004) 719-735
-
(2004)
Pharm. Res.
, vol.21
, pp. 719-735
-
-
Chandra, P.1
Brouwer, K.L.R.2
-
20
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole S.P., Bhardwaj G., Gerlach J.H., Mackie J.E., Grant C.E., Almquist K.C., Stewart A.J., Kurz E.U., Duncan A.M., and Deeley R.G. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 258 (1992) 1650-1654
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Duncan, A.M.9
Deeley, R.G.10
-
21
-
-
0035793123
-
Sequencing and tissue distribution of the canine MRP2 gene compared with MRP1 and MDR1
-
Conrad S., Viertelhaus A., Orzechowski A., Hoogstraate J., Gjellan K., Schrenk D., and Kauffmann H.M. Sequencing and tissue distribution of the canine MRP2 gene compared with MRP1 and MDR1. Toxicology 156 (2001) 81-91
-
(2001)
Toxicology
, vol.156
, pp. 81-91
-
-
Conrad, S.1
Viertelhaus, A.2
Orzechowski, A.3
Hoogstraate, J.4
Gjellan, K.5
Schrenk, D.6
Kauffmann, H.M.7
-
22
-
-
0025071180
-
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
-
Cordon-Cardo C., O'Brien J., Boccia J., Casals D., Bertino J., and Melamed M. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J. Histochem. Cytochem. 38 (1990) 1277-1287
-
(1990)
J. Histochem. Cytochem.
, vol.38
, pp. 1277-1287
-
-
Cordon-Cardo, C.1
O'Brien, J.2
Boccia, J.3
Casals, D.4
Bertino, J.5
Melamed, M.6
-
23
-
-
3543068267
-
Quantification of MDR-1 gene expression in canine tissues by real-time reverse transcription quantitative polymerase chain reaction
-
Culmsee K., Gruber A.D., von Samson-Himmelstjerna G., and Nolte I. Quantification of MDR-1 gene expression in canine tissues by real-time reverse transcription quantitative polymerase chain reaction. Res. Vet. Sci. 77 (2004) 223-229
-
(2004)
Res. Vet. Sci.
, vol.77
, pp. 223-229
-
-
Culmsee, K.1
Gruber, A.D.2
von Samson-Himmelstjerna, G.3
Nolte, I.4
-
24
-
-
0036099409
-
More economical use of cyclosporine through combination drug therapy
-
Daigle J.C. More economical use of cyclosporine through combination drug therapy. J. Am. Anim. Hosp. Assoc. 38 (2002) 205-208
-
(2002)
J. Am. Anim. Hosp. Assoc.
, vol.38
, pp. 205-208
-
-
Daigle, J.C.1
-
25
-
-
0026467167
-
Cyclosporin and quinidine inhibition of renal digoxin excretion: evidence for luminal secretion of digoxin
-
De Lannoy I.A., Koren G., Klein J., Charuk J., and Silverman M. Cyclosporin and quinidine inhibition of renal digoxin excretion: evidence for luminal secretion of digoxin. Am. J. Physiol. 263 (1992) F613-F622
-
(1992)
Am. J. Physiol.
, vol.263
-
-
De Lannoy, I.A.1
Koren, G.2
Klein, J.3
Charuk, J.4
Silverman, M.5
-
26
-
-
0033040149
-
P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia: results of a 6-year prospective study
-
Dhooge C., De Moerloose B., Laureys G., Kint J., Ferster A., De Bacquer D., Philippe J., and Benoit Y. P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukaemia: results of a 6-year prospective study. Br. J. Haematol. 105 (1999) 676-683
-
(1999)
Br. J. Haematol.
, vol.105
, pp. 676-683
-
-
Dhooge, C.1
De Moerloose, B.2
Laureys, G.3
Kint, J.4
Ferster, A.5
De Bacquer, D.6
Philippe, J.7
Benoit, Y.8
-
27
-
-
0035034532
-
Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats
-
Dietrich C.G., de Waart D.R., Ottenhoff R., Schoots I.G., and Elferink R.P.J.O. Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats. Mol. Pharmacol. 59 (2001) 974-980
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 974-980
-
-
Dietrich, C.G.1
de Waart, D.R.2
Ottenhoff, R.3
Schoots, I.G.4
Elferink, R.P.J.O.5
-
28
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
Doyle L.A., Yang W., Abruzzo L.V., Krogmann T., Gao Y., Rishi A.K., and Ross D.D. A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc. Natl. Acad. Sci. U S A 95 (1998) 15665-15670
-
(1998)
Proc. Natl. Acad. Sci. U S A
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
Ross, D.D.7
-
29
-
-
0037373631
-
P-glycoprotein-mediated intestinal and biliary digoxin transport in humans
-
Drescher S., Glaeser H., Murdter T., Hitzl M., Eichelbaum M., and Fromm M.F. P-glycoprotein-mediated intestinal and biliary digoxin transport in humans. Clin. Pharmacol. Ther. 73 (2003) 223-231
-
(2003)
Clin. Pharmacol. Ther.
, vol.73
, pp. 223-231
-
-
Drescher, S.1
Glaeser, H.2
Murdter, T.3
Hitzl, M.4
Eichelbaum, M.5
Fromm, M.F.6
-
30
-
-
33644674983
-
The interaction between moxidectin and MDR transporters in primary cultures of rat hepatocytes
-
Dupuy J., Lespine A., Sutra J.F., and Alvinerie M. The interaction between moxidectin and MDR transporters in primary cultures of rat hepatocytes. J. Vet. Pharmacol. Ther. 29 (2006) 107-111
-
(2006)
J. Vet. Pharmacol. Ther.
, vol.29
, pp. 107-111
-
-
Dupuy, J.1
Lespine, A.2
Sutra, J.F.3
Alvinerie, M.4
-
31
-
-
36249014207
-
Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies
-
Eberl S., Renner B., Neubert A., Reisig M., Bachmakov I., Konig J., Dorje F., Murdter T.E., Ackermann A., Dormann H., Gassmann K.G., Hahn E.G., Zierhut S., Brune K., and Fromm M.F. Role of p-glycoprotein inhibition for drug interactions: evidence from in vitro and pharmacoepidemiological studies. Clin. Pharmacokinet. 46 (2007) 1039-1049
-
(2007)
Clin. Pharmacokinet.
, vol.46
, pp. 1039-1049
-
-
Eberl, S.1
Renner, B.2
Neubert, A.3
Reisig, M.4
Bachmakov, I.5
Konig, J.6
Dorje, F.7
Murdter, T.E.8
Ackermann, A.9
Dormann, H.10
Gassmann, K.G.11
Hahn, E.G.12
Zierhut, S.13
Brune, K.14
Fromm, M.F.15
-
32
-
-
0032982612
-
Cmdr1, a chicken P-glycoprotein, confers multidrug resistance and interacts with estradiol
-
Edelmann H.M., Duchek P., Rosenthal F.E., Foger N., Glackin C., Kane S.E., and Kuchler K. Cmdr1, a chicken P-glycoprotein, confers multidrug resistance and interacts with estradiol. Biol. Chem. 380 (1999) 231-241
-
(1999)
Biol. Chem.
, vol.380
, pp. 231-241
-
-
Edelmann, H.M.1
Duchek, P.2
Rosenthal, F.E.3
Foger, N.4
Glackin, C.5
Kane, S.E.6
Kuchler, K.7
-
33
-
-
0036086485
-
A new multidrug resistance protein at the blood-brain barrier
-
Eisenblatter T., and Galla H.J. A new multidrug resistance protein at the blood-brain barrier. Biochem. Biophys. Res. Commun. 293 (2002) 1273-1278
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 1273-1278
-
-
Eisenblatter, T.1
Galla, H.J.2
-
34
-
-
34249095550
-
Regional expression and activity of breast cancer resistance protein (Bcrp/Abcg2) in mouse intestine: overlapping distribution with sulfotransferases
-
Enokizono J., Kusuhara H., and Sugiyama Y. Regional expression and activity of breast cancer resistance protein (Bcrp/Abcg2) in mouse intestine: overlapping distribution with sulfotransferases. Drug Metab. Dispos. 35 (2007) 922-928
-
(2007)
Drug Metab. Dispos.
, vol.35
, pp. 922-928
-
-
Enokizono, J.1
Kusuhara, H.2
Sugiyama, Y.3
-
35
-
-
35848932291
-
Pharmacokinetics of danofloxacin 18% in lactating sheep and goats
-
Escudero E., Carceles C.M., Fernandez-varon E., Marin P., and Benchaoui H. Pharmacokinetics of danofloxacin 18% in lactating sheep and goats. J. Vet. Pharmacol. Ther. 30 (2007) 572-577
-
(2007)
J. Vet. Pharmacol. Ther.
, vol.30
, pp. 572-577
-
-
Escudero, E.1
Carceles, C.M.2
Fernandez-varon, E.3
Marin, P.4
Benchaoui, H.5
-
36
-
-
0042132423
-
Expression of a multidrug-resistance gene in human tumors and tissues
-
Fojo A.T., Ueda K., Slamon D.J., Poplack D.G., Gottesman M.M., and Pastan I. Expression of a multidrug-resistance gene in human tumors and tissues. Proc. Natl. Acad. Sci. U S A 84 (1987) 265-269
-
(1987)
Proc. Natl. Acad. Sci. U S A
, vol.84
, pp. 265-269
-
-
Fojo, A.T.1
Ueda, K.2
Slamon, D.J.3
Poplack, D.G.4
Gottesman, M.M.5
Pastan, I.6
-
37
-
-
0013185331
-
Penetration of danofloxacin into the respiratory tract tissues and secretions in healthy and Actinobacillus pleuropneumoniae infected pigs
-
Friis C., and Nielsen J.P. Penetration of danofloxacin into the respiratory tract tissues and secretions in healthy and Actinobacillus pleuropneumoniae infected pigs. J. Vet. Pharm. Ther. 20 (1997) 87-109
-
(1997)
J. Vet. Pharm. Ther.
, vol.20
, pp. 87-109
-
-
Friis, C.1
Nielsen, J.P.2
-
38
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine
-
Fromm M.F., Kim R.B., Stein C.M., Wilkinson G.R., and Roden D.M. Inhibition of P-glycoprotein-mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine. Circulation 99 (1999) 552-557
-
(1999)
Circulation
, vol.99
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
39
-
-
28444453357
-
Frequency of the nt230 (del4) MDR1 mutation in collies and related dog breeds in Germany
-
Geyer J., Doring B., Godoy J.R., Leidolf R., Moritz A., and Petzinger E. Frequency of the nt230 (del4) MDR1 mutation in collies and related dog breeds in Germany. J. Vet. Pharmacol. Ther. 28 (2005) 545-551
-
(2005)
J. Vet. Pharmacol. Ther.
, vol.28
, pp. 545-551
-
-
Geyer, J.1
Doring, B.2
Godoy, J.R.3
Leidolf, R.4
Moritz, A.5
Petzinger, E.6
-
40
-
-
14844346526
-
Development of a PCR-based diagnostic test detecting a nt230(del4) MDR1 mutation in dogs: verification in a moxidectin-sensitive Australian Shepherd
-
Geyer J., Doring B., Godoy J.R., Moritz A., and Petzinger E. Development of a PCR-based diagnostic test detecting a nt230(del4) MDR1 mutation in dogs: verification in a moxidectin-sensitive Australian Shepherd. J. Vet. Pharmacol. Ther. 28 (2005) 95-99
-
(2005)
J. Vet. Pharmacol. Ther.
, vol.28
, pp. 95-99
-
-
Geyer, J.1
Doring, B.2
Godoy, J.R.3
Moritz, A.4
Petzinger, E.5
-
41
-
-
34548418502
-
Detection of the nt230(del4) MDR1 mutation in White Swiss Shepherd dogs: case reports of doramectin toxicosis, breed predisposition, and microsatellite analysis
-
Geyer J., Klintzsch S., Meerkamp K., Wohlke A., Distl O., Moritz A., and Petzinger E. Detection of the nt230(del4) MDR1 mutation in White Swiss Shepherd dogs: case reports of doramectin toxicosis, breed predisposition, and microsatellite analysis. J. Vet. Pharmacol. Ther. 30 (2007) 482-485
-
(2007)
J. Vet. Pharmacol. Ther.
, vol.30
, pp. 482-485
-
-
Geyer, J.1
Klintzsch, S.2
Meerkamp, K.3
Wohlke, A.4
Distl, O.5
Moritz, A.6
Petzinger, E.7
-
42
-
-
34250219965
-
Chemotherapy-induced resistance by ATP-binding cassette transporter genes
-
Gillet J.P., Efferth T., and Remacle J. Chemotherapy-induced resistance by ATP-binding cassette transporter genes. Biochim. Biophys. Acta 1775 (2007) 237-262
-
(2007)
Biochim. Biophys. Acta
, vol.1775
, pp. 237-262
-
-
Gillet, J.P.1
Efferth, T.2
Remacle, J.3
-
43
-
-
0030227521
-
Immunohistochemical detection of P-glycoprotein in formalin-fixed and paraffin-embedded normal and neoplastic canine tissues
-
Ginn P.E. Immunohistochemical detection of P-glycoprotein in formalin-fixed and paraffin-embedded normal and neoplastic canine tissues. Vet. Pathol. 33 (1996) 533-541
-
(1996)
Vet. Pathol.
, vol.33
, pp. 533-541
-
-
Ginn, P.E.1
-
44
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
Greiner B., Eichelbaum M., Fritz P., Kreichgauer H.P., von Richter O., Zundler J., and Kroemer H.K. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J. Clin. Invest. 104 (1999) 147-153
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
von Richter, O.5
Zundler, J.6
Kroemer, H.K.7
-
45
-
-
21244452361
-
Selamectin is a potent substrate and inhibitor of human and canine P-glycoprotein
-
Griffin J., Fletcher N., Clemence R., Blanchflower S., and Brayden D.J. Selamectin is a potent substrate and inhibitor of human and canine P-glycoprotein. J. Vet. Pharmacol. Ther. 28 (2005) 257-265
-
(2005)
J. Vet. Pharmacol. Ther.
, vol.28
, pp. 257-265
-
-
Griffin, J.1
Fletcher, N.2
Clemence, R.3
Blanchflower, S.4
Brayden, D.J.5
-
46
-
-
0022515908
-
Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells
-
Gros P., Croop J., Roninson I., Varshavsky A., and Housman D.E. Isolation and characterization of DNA sequences amplified in multidrug-resistant hamster cells. Proc. Natl. Acad. Sci. U S A 83 (1986) 337-341
-
(1986)
Proc. Natl. Acad. Sci. U S A
, vol.83
, pp. 337-341
-
-
Gros, P.1
Croop, J.2
Roninson, I.3
Varshavsky, A.4
Housman, D.E.5
-
47
-
-
0034718544
-
CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)
-
Handschin C., Podvinec M., and Meyer U.A. CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR). Proc. Natl. Acad. Sci. U S A 97 (2000) 10769-10774
-
(2000)
Proc. Natl. Acad. Sci. U S A
, vol.97
, pp. 10769-10774
-
-
Handschin, C.1
Podvinec, M.2
Meyer, U.A.3
-
48
-
-
43049169189
-
-
Haritova, A.M., 2006. PK-PD modeling of fluoroquinolones and ABC transporters in poultry, in: Veterinary Pharmacology, Pharmacy and Toxicology, Vol. Ph.D. (Utrecht University, Utrecht).
-
Haritova, A.M., 2006. PK-PD modeling of fluoroquinolones and ABC transporters in poultry, in: Veterinary Pharmacology, Pharmacy and Toxicology, Vol. Ph.D. (Utrecht University, Utrecht).
-
-
-
-
49
-
-
0026092531
-
Digoxin-verapamil interaction: reduction of biliary but not renal digoxin clearance in humans
-
Hedman A., Angelin B., Arvidsson A., Beck O., Dahlqvist R., Nilsson B., Olsson M., and Schenck-Gustafsson K. Digoxin-verapamil interaction: reduction of biliary but not renal digoxin clearance in humans. Clin. Pharmacol. Ther. 49 (1991) 256-262
-
(1991)
Clin. Pharmacol. Ther.
, vol.49
, pp. 256-262
-
-
Hedman, A.1
Angelin, B.2
Arvidsson, A.3
Beck, O.4
Dahlqvist, R.5
Nilsson, B.6
Olsson, M.7
Schenck-Gustafsson, K.8
-
51
-
-
0036007742
-
St Johns wort increases expression of P-glycoprotein: implications for drug interactions
-
Hennessy M., Kelleher D., Spiers J.P., Barry M., Kavanagh P., Back D., Mulcahy F., and Feely J. St Johns wort increases expression of P-glycoprotein: implications for drug interactions. Br. J. Clin. Pharmacol. 53 (2002) 75-82
-
(2002)
Br. J. Clin. Pharmacol.
, vol.53
, pp. 75-82
-
-
Hennessy, M.1
Kelleher, D.2
Spiers, J.P.3
Barry, M.4
Kavanagh, P.5
Back, D.6
Mulcahy, F.7
Feely, J.8
-
52
-
-
34547872714
-
Anti-emetic therapy in cancer chemotherapy: current status
-
Herrstedt J., and Dombernowsky P. Anti-emetic therapy in cancer chemotherapy: current status. Basic Clin. Pharmacol. Toxicol. 101 (2007) 143-150
-
(2007)
Basic Clin. Pharmacol. Toxicol.
, vol.101
, pp. 143-150
-
-
Herrstedt, J.1
Dombernowsky, P.2
-
53
-
-
29744441900
-
Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk 10.1093/carcin/bgi176
-
Herwaarden A.E.v., Wagenaar E., Karnekamp B., Merino G., Jonker J.W., and Schinkel A.H. Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk 10.1093/carcin/bgi176. Carcinogenesis 27 (2006) 123-130
-
(2006)
Carcinogenesis
, vol.27
, pp. 123-130
-
-
Herwaarden, A.E.v.1
Wagenaar, E.2
Karnekamp, B.3
Merino, G.4
Jonker, J.W.5
Schinkel, A.H.6
-
54
-
-
23944475903
-
Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin
-
10.1124/mol.105.014019
-
Hirano M., Maeda K., Matsushima S., Nozaki Y., Kusuhara H., and Sugiyama Y. Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin. Mol. Pharmacol. 68 (2005) 800-807 10.1124/mol.105.014019
-
(2005)
Mol. Pharmacol.
, vol.68
, pp. 800-807
-
-
Hirano, M.1
Maeda, K.2
Matsushima, S.3
Nozaki, Y.4
Kusuhara, H.5
Sugiyama, Y.6
-
55
-
-
0031691234
-
The role of P-glycoprotein and canalicular multispecific organic anion transporter in the hepatobiliary excretion of drugs
-
Hiroyuki Kusuhara H.S., and Yuichi S. The role of P-glycoprotein and canalicular multispecific organic anion transporter in the hepatobiliary excretion of drugs. J. Pharm. Sci. 87 (1998) 1025-1040
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 1025-1040
-
-
Hiroyuki Kusuhara, H.S.1
Yuichi, S.2
-
56
-
-
37549068911
-
The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane
-
Huls M., Brown C.D., Windass A.S., Sayer R., van den Heuvel J.J., Heemskerk S., Russel F.G., and Masereeuw R. The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane. Kidney Int. 73 (2008) 220-225
-
(2008)
Kidney Int.
, vol.73
, pp. 220-225
-
-
Huls, M.1
Brown, C.D.2
Windass, A.S.3
Sayer, R.4
van den Heuvel, J.J.5
Heemskerk, S.6
Russel, F.G.7
Masereeuw, R.8
-
57
-
-
34548295855
-
Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux
-
Igel S., Drescher S., Murdter T., Hofmann U., Heinkele G., Tegude H., Glaeser H., Brenner S.S., Somogyi A.A., Omari T., Schafer C., Eichelbaum M., and Fromm M.F. Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux. Clin. Pharmacokinet. 46 (2007) 777-785
-
(2007)
Clin. Pharmacokinet.
, vol.46
, pp. 777-785
-
-
Igel, S.1
Drescher, S.2
Murdter, T.3
Hofmann, U.4
Heinkele, G.5
Tegude, H.6
Glaeser, H.7
Brenner, S.S.8
Somogyi, A.A.9
Omari, T.10
Schafer, C.11
Eichelbaum, M.12
Fromm, M.F.13
-
58
-
-
4744364039
-
Milk excretion of ivermectin and moxidectin in dairy sheep: assessment of drug residues during cheese elaboration and ripening period
-
Imperiale F.A., Busetti M.R., Suarez V.H., and Lanusse C.E. Milk excretion of ivermectin and moxidectin in dairy sheep: assessment of drug residues during cheese elaboration and ripening period. J. Agric. Food Chem. 52 (2004) 6205-6211
-
(2004)
J. Agric. Food Chem.
, vol.52
, pp. 6205-6211
-
-
Imperiale, F.A.1
Busetti, M.R.2
Suarez, V.H.3
Lanusse, C.E.4
-
59
-
-
0032806043
-
Species differences in the transport activity for organic anions across the bile canalicular membrane
-
Ishizuka H., Konno K., Shiina T., Naganuma H., Nishimura K., Ito K., Suzuki H., and Sugiyama Y. Species differences in the transport activity for organic anions across the bile canalicular membrane. J. Pharmacol. Exp. Ther. 290 (1999) 1324-1330
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.290
, pp. 1324-1330
-
-
Ishizuka, H.1
Konno, K.2
Shiina, T.3
Naganuma, H.4
Nishimura, K.5
Ito, K.6
Suzuki, H.7
Sugiyama, Y.8
-
60
-
-
0023273521
-
Chromosomal localization of three genes coamplified in the multidrug-resistant CHRC5 Chinese hamster ovary cell line
-
Jongsma A.P., Spengler B.A., Van der Bliek A.M., Borst P., and Biedler J.L. Chromosomal localization of three genes coamplified in the multidrug-resistant CHRC5 Chinese hamster ovary cell line. Cancer Res. 47 (1987) 2875-2878
-
(1987)
Cancer Res.
, vol.47
, pp. 2875-2878
-
-
Jongsma, A.P.1
Spengler, B.A.2
Van der Bliek, A.M.3
Borst, P.4
Biedler, J.L.5
-
61
-
-
0037180446
-
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
-
Jonker J.W., Buitelaar M., Wagenaar E., Van Der Valk M.A., Scheffer G.L., Scheper R.J., Plosch T., Kuipers F., Elferink R.P., Rosing H., Beijnen J.H., and Schinkel A.H. The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc. Natl. Acad. Sci. U S A 99 (2002) 15649-15654
-
(2002)
Proc. Natl. Acad. Sci. U S A
, vol.99
, pp. 15649-15654
-
-
Jonker, J.W.1
Buitelaar, M.2
Wagenaar, E.3
Van Der Valk, M.A.4
Scheffer, G.L.5
Scheper, R.J.6
Plosch, T.7
Kuipers, F.8
Elferink, R.P.9
Rosing, H.10
Beijnen, J.H.11
Schinkel, A.H.12
-
62
-
-
14644409841
-
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
-
Jonker J.W., Merino G., Musters S., van Herwaarden A.E., Bolscher E., Wagenaar E., Mesman E., Dale T.C., and Schinkel A.H. The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nat. Med. 11 (2005) 127-129
-
(2005)
Nat. Med.
, vol.11
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
Mesman, E.7
Dale, T.C.8
Schinkel, A.H.9
-
63
-
-
0034684120
-
Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan
-
Jonker J.W., Smit J.W., Brinkhuis R.F., Maliepaard M., Beijnen J.H., Schellens J.H.M., and Schinkel A.H. Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan. J. Natl. Cancer Inst. 92 (2000) 1651-1656
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 1651-1656
-
-
Jonker, J.W.1
Smit, J.W.2
Brinkhuis, R.F.3
Maliepaard, M.4
Beijnen, J.H.5
Schellens, J.H.M.6
Schinkel, A.H.7
-
64
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano R.L., and Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta 455 (1976) 152-162
-
(1976)
Biochim. Biophys. Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
65
-
-
0028792577
-
Pharmacokinetics of enrofloxacin after single intravenous, intramuscular and subcutaneous injections in lactating cows
-
Kaartinen L., Salonen M., Alli L., and Pyorala S. Pharmacokinetics of enrofloxacin after single intravenous, intramuscular and subcutaneous injections in lactating cows. J. Vet. Pharmacol. Ther. 18 (1995) 357-362
-
(1995)
J. Vet. Pharmacol. Ther.
, vol.18
, pp. 357-362
-
-
Kaartinen, L.1
Salonen, M.2
Alli, L.3
Pyorala, S.4
-
66
-
-
33645551838
-
Relationship between excretion clearance of rhodamine 123 and P-glycoprotein (Pgp) expression induced by representative Pgp inducers
-
Kageyama M., Fukushima K., Togawa T., Fujimoto K., Taki M., Nishimura A., Ito Y., Sugioka N., Shibata N., and Takada K. Relationship between excretion clearance of rhodamine 123 and P-glycoprotein (Pgp) expression induced by representative Pgp inducers. Biol. Pharm. Bull. 29 (2006) 779-784
-
(2006)
Biol. Pharm. Bull.
, vol.29
, pp. 779-784
-
-
Kageyama, M.1
Fukushima, K.2
Togawa, T.3
Fujimoto, K.4
Taki, M.5
Nishimura, A.6
Ito, Y.7
Sugioka, N.8
Shibata, N.9
Takada, K.10
-
67
-
-
33846261622
-
Kinetic analyses for species differences in P-glycoprotein-mediated drug transport
-
Katoh M., Suzuyama N., Takeuchi T., Yoshitomi S., Asahi S., and Yokoi T. Kinetic analyses for species differences in P-glycoprotein-mediated drug transport. J. Pharm. Sci. 95 (2006) 2673-2683
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 2673-2683
-
-
Katoh, M.1
Suzuyama, N.2
Takeuchi, T.3
Yoshitomi, S.4
Asahi, S.5
Yokoi, T.6
-
68
-
-
33644781452
-
Implications of genetic polymorphisms in drug transporters for pharmacotherapy
-
Kerb R. Implications of genetic polymorphisms in drug transporters for pharmacotherapy. Cancer Lett. 234 (2006) 4-33
-
(2006)
Cancer Lett.
, vol.234
, pp. 4-33
-
-
Kerb, R.1
-
69
-
-
0032518290
-
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors
-
Kim R.B., Fromm M.F., Wandel C., Leake B., Wood A.J., Roden D.M., and Wilkinson G.R. The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors. J. Clin. Invest. 101 (1998) 289-294
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 289-294
-
-
Kim, R.B.1
Fromm, M.F.2
Wandel, C.3
Leake, B.4
Wood, A.J.5
Roden, D.M.6
Wilkinson, G.R.7
-
70
-
-
0026734708
-
Defective biliary excretion of epinephrine metabolites in mutant (TR-) rats: relation to the pathogenesis of black liver in the Dubin-Johnson syndrome and Corriedale sheep with an analogous excretory defect
-
Kitamura T., Alroy J., Gatmaitan Z., Inoue M., Mikami T., Jansen P., and Arias I.M. Defective biliary excretion of epinephrine metabolites in mutant (TR-) rats: relation to the pathogenesis of black liver in the Dubin-Johnson syndrome and Corriedale sheep with an analogous excretory defect. Hepatology 15 (1992) 1154-1159
-
(1992)
Hepatology
, vol.15
, pp. 1154-1159
-
-
Kitamura, T.1
Alroy, J.2
Gatmaitan, Z.3
Inoue, M.4
Mikami, T.5
Jansen, P.6
Arias, I.M.7
-
71
-
-
0344927562
-
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
-
Konig J., Nies A.T., Cui Y., Leier I., and Keppler D. Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance. Biochim. Biophys. Acta 1461 (1999) 377-394
-
(1999)
Biochim. Biophys. Acta
, vol.1461
, pp. 377-394
-
-
Konig, J.1
Nies, A.T.2
Cui, Y.3
Leier, I.4
Keppler, D.5
-
72
-
-
0030841332
-
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
-
Kool M., de Haas M., Scheffer G.L., Scheper R.J., van Eijk M.J., Juijn J.A., Baas F., and Borst P. Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res. 57 (1997) 3537-3547
-
(1997)
Cancer Res.
, vol.57
, pp. 3537-3547
-
-
Kool, M.1
de Haas, M.2
Scheffer, G.L.3
Scheper, R.J.4
van Eijk, M.J.5
Juijn, J.A.6
Baas, F.7
Borst, P.8
-
73
-
-
0036909078
-
Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview
-
Kruijtzer C.M., Beijnen J.H., and Schellens J.H. Improvement of oral drug treatment by temporary inhibition of drug transporters and/or cytochrome P450 in the gastrointestinal tract and liver: an overview. Oncologist 7 (2002) 516-530
-
(2002)
Oncologist
, vol.7
, pp. 516-530
-
-
Kruijtzer, C.M.1
Beijnen, J.H.2
Schellens, J.H.3
-
75
-
-
40549113956
-
P-glycoprotein limits oral availability, brain penetration and toxicity of an anionic drug, the antibiotic salinomycin
-
Lagas J.S., Sparidans R.W., van Waterschoot R.A., Wagenaar E., Beijnen J.H., and Schinkel A.H. P-glycoprotein limits oral availability, brain penetration and toxicity of an anionic drug, the antibiotic salinomycin. Antimicrob. Agents. Chemother. 52 (2008) 1034-1039
-
(2008)
Antimicrob. Agents. Chemother.
, vol.52
, pp. 1034-1039
-
-
Lagas, J.S.1
Sparidans, R.W.2
van Waterschoot, R.A.3
Wagenaar, E.4
Beijnen, J.H.5
Schinkel, A.H.6
-
76
-
-
34548428278
-
Estimation of absolute oral bioavailability of moxidectin in dogs using a semi-simultaneous method: influence of lipid co-administration
-
Lallemand E., Lespine A., Alvinerie M., Bousquet-Melou A., and Toutain P.L. Estimation of absolute oral bioavailability of moxidectin in dogs using a semi-simultaneous method: influence of lipid co-administration. J. Vet. Pharmacol. Ther. 30 (2007) 375-380
-
(2007)
J. Vet. Pharmacol. Ther.
, vol.30
, pp. 375-380
-
-
Lallemand, E.1
Lespine, A.2
Alvinerie, M.3
Bousquet-Melou, A.4
Toutain, P.L.5
-
77
-
-
6344266966
-
Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences
-
Lamba J.K., Lamba V., Yasuda K., Lin Y.S., Assem M., Thompson E., Strom S., and Schuetz E. Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. J. Pharmacol. Exp. Ther. 311 (2004) 811-821
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.311
, pp. 811-821
-
-
Lamba, J.K.1
Lamba, V.2
Yasuda, K.3
Lin, Y.S.4
Assem, M.5
Thompson, E.6
Strom, S.7
Schuetz, E.8
-
78
-
-
0037305372
-
Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues
-
Langmann T., Mauerer R., Zahn A., Moehle C., Probst M., Stremmel W., and Schmitz G. Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues. Clin. Chem. 49 (2003) 230-238
-
(2003)
Clin. Chem.
, vol.49
, pp. 230-238
-
-
Langmann, T.1
Mauerer, R.2
Zahn, A.3
Moehle, C.4
Probst, M.5
Stremmel, W.6
Schmitz, G.7
-
79
-
-
0029965253
-
P-glycoprotein expression in canine lymphoma: a relevant, intermediate model of multidrug resistance
-
Lee J.J., Hughes C.S., Fine R.L., and Page R.L. P-glycoprotein expression in canine lymphoma: a relevant, intermediate model of multidrug resistance. Cancer 77 (1996) 1892-1898
-
(1996)
Cancer
, vol.77
, pp. 1892-1898
-
-
Lee, J.J.1
Hughes, C.S.2
Fine, R.L.3
Page, R.L.4
-
80
-
-
33645821869
-
Reversal of MDR1 gene-dependent multidrug resistance using low concentration of endonuclease-prepared small interference RNA
-
Li L., Xu J., Min T., and Huang W. Reversal of MDR1 gene-dependent multidrug resistance using low concentration of endonuclease-prepared small interference RNA. Eur. J. Pharmacol. 536 (2006) 93-97
-
(2006)
Eur. J. Pharmacol.
, vol.536
, pp. 93-97
-
-
Li, L.1
Xu, J.2
Min, T.3
Huang, W.4
-
81
-
-
0033944156
-
Pharmacokinetics and penetration of danofloxacin into the gastrointestinal tract in healthy and in Salmonella typhimurium infected pigs
-
Lindecrona R.H., Friis C., and Nielsen J.P. Pharmacokinetics and penetration of danofloxacin into the gastrointestinal tract in healthy and in Salmonella typhimurium infected pigs. Res. Vet. Sci. 68 (2000) 211-216
-
(2000)
Res. Vet. Sci.
, vol.68
, pp. 211-216
-
-
Lindecrona, R.H.1
Friis, C.2
Nielsen, J.P.3
-
82
-
-
33745248116
-
Vectorial transport of enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers
-
Liu L., Cui Y., Chung A.Y., Shitara Y., Sugiyama Y., Keppler D., and Pang K.S. Vectorial transport of enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers. J. Pharmacol. Exp. Ther. 318 (2006) 395-402
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.318
, pp. 395-402
-
-
Liu, L.1
Cui, Y.2
Chung, A.Y.3
Shitara, Y.4
Sugiyama, Y.5
Keppler, D.6
Pang, K.S.7
-
83
-
-
0037704286
-
Identification and characterization of the canine multidrug resistance-associated protein
-
Ma L., Pratt S.E., Cao J., Dantzig A.H., Moore R.E., and Slapak C.A. Identification and characterization of the canine multidrug resistance-associated protein. Mol. Cancer Ther. 1 (2002) 1335-1342
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 1335-1342
-
-
Ma, L.1
Pratt, S.E.2
Cao, J.3
Dantzig, A.H.4
Moore, R.E.5
Slapak, C.A.6
-
84
-
-
0035870289
-
Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues
-
Maliepaard M., Scheffer G.L., Faneyte I.F., van Gastelen M.A., Pijnenborg A.C., Schinkel A.H., van De Vijver M.J., Scheper R.J., and Schellens J.H. Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res. 61 (2001) 3458-3464
-
(2001)
Cancer Res.
, vol.61
, pp. 3458-3464
-
-
Maliepaard, M.1
Scheffer, G.L.2
Faneyte, I.F.3
van Gastelen, M.A.4
Pijnenborg, A.C.5
Schinkel, A.H.6
van De Vijver, M.J.7
Scheper, R.J.8
Schellens, J.H.9
-
85
-
-
33749443439
-
In vivo animal models for investigating potential CYP3A- and Pgp-mediated drug-drug interactions
-
Marathe P.H., and Rodrigues A.D. In vivo animal models for investigating potential CYP3A- and Pgp-mediated drug-drug interactions. Curr. Drug Metab. 7 (2006) 687-704
-
(2006)
Curr. Drug Metab.
, vol.7
, pp. 687-704
-
-
Marathe, P.H.1
Rodrigues, A.D.2
-
86
-
-
0029133131
-
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes
-
Mayer R., Kartenbeck J., Buchler M., Jedlitschky G., Leier I., and Keppler D. Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes. J. Cell Biol. 131 (1995) 137-150
-
(1995)
J. Cell Biol.
, vol.131
, pp. 137-150
-
-
Mayer, R.1
Kartenbeck, J.2
Buchler, M.3
Jedlitschky, G.4
Leier, I.5
Keppler, D.6
-
87
-
-
0029860174
-
Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein
-
Mayer U., Wagenaar E., Beijnen J.H., Smit J.W., Meijer D.K., van Asperen J., Borst P., and Schinkel A.H. Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein. Br. J. Pharmacol. 119 (1996) 1038-1044
-
(1996)
Br. J. Pharmacol.
, vol.119
, pp. 1038-1044
-
-
Mayer, U.1
Wagenaar, E.2
Beijnen, J.H.3
Smit, J.W.4
Meijer, D.K.5
van Asperen, J.6
Borst, P.7
Schinkel, A.H.8
-
88
-
-
8344252959
-
Enhanced bioavailability of oral docetaxel by co-administration of cyclosporin A in dogs and rats
-
McEntee M., Silverman J.A., Rassnick K., Zgola M., Chan A.O., Tau P.T., and Page R.L. Enhanced bioavailability of oral docetaxel by co-administration of cyclosporin A in dogs and rats. Vet. Comp. Oncol. 1 (2003) 105-112
-
(2003)
Vet. Comp. Oncol.
, vol.1
, pp. 105-112
-
-
McEntee, M.1
Silverman, J.A.2
Rassnick, K.3
Zgola, M.4
Chan, A.O.5
Tau, P.T.6
Page, R.L.7
-
89
-
-
33845706632
-
Phase I and pharmacokinetic evaluation of the combination of orally administered docetaxel and cyclosporin A in tumor-bearing cats
-
McEntee M.C., Rassnick K.M., Bailey D.B., Balkman C.E., Flanagan J.L., Beaulieu B.B., Zgola M.M., Lewis L.D., and Page R.L. Phase I and pharmacokinetic evaluation of the combination of orally administered docetaxel and cyclosporin A in tumor-bearing cats. J. Vet. Intern. Med. 20 (2006) 1370-1375
-
(2006)
J. Vet. Intern. Med.
, vol.20
, pp. 1370-1375
-
-
McEntee, M.C.1
Rassnick, K.M.2
Bailey, D.B.3
Balkman, C.E.4
Flanagan, J.L.5
Beaulieu, B.B.6
Zgola, M.M.7
Lewis, L.D.8
Page, R.L.9
-
90
-
-
33745675665
-
Phase I and pharmacokinetic evaluation of the combination of orally administered docetaxel and cyclosporin A in tumor-bearing dogs
-
McEntee M.C., Rassnick K.M., Lewis L.D., Zgola M.M., Beaulieu B.B., Balkman C.E., and Page R.L. Phase I and pharmacokinetic evaluation of the combination of orally administered docetaxel and cyclosporin A in tumor-bearing dogs. Am. J. Vet. Res. 67 (2006) 1057-1062
-
(2006)
Am. J. Vet. Res.
, vol.67
, pp. 1057-1062
-
-
McEntee, M.C.1
Rassnick, K.M.2
Lewis, L.D.3
Zgola, M.M.4
Beaulieu, B.B.5
Balkman, C.E.6
Page, R.L.7
-
92
-
-
2942520858
-
A new tool that detects ivermectin and other drug sensitivities in dogs
-
Mealey K.L. A new tool that detects ivermectin and other drug sensitivities in dogs. Vet. Med. 99 (2004) 419-426
-
(2004)
Vet. Med.
, vol.99
, pp. 419-426
-
-
Mealey, K.L.1
-
94
-
-
0035164622
-
Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene
-
Mealey K.L., Bentjen S.A., Gay J.M., and Cantor G.H. Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene. Pharmacogenetics 11 (2001) 727-733
-
(2001)
Pharmacogenetics
, vol.11
, pp. 727-733
-
-
Mealey, K.L.1
Bentjen, S.A.2
Gay, J.M.3
Cantor, G.H.4
-
95
-
-
0242523974
-
Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity
-
1434
-
Mealey K.L., Northrup N.C., and Bentjen S.A. Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity. J. Am. Vet. Med. Assoc. 223 (2003) 1453-1455 1434
-
(2003)
J. Am. Vet. Med. Assoc.
, vol.223
, pp. 1453-1455
-
-
Mealey, K.L.1
Northrup, N.C.2
Bentjen, S.A.3
-
96
-
-
33645108568
-
Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion
-
Merino G., Alvarez A.I., Pulido M.M., Molina A.J., Schinkel A.H., and Prieto J.G. Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion. Drug Metab. Dispos. 34 (2006) 690-695
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 690-695
-
-
Merino, G.1
Alvarez, A.I.2
Pulido, M.M.3
Molina, A.J.4
Schinkel, A.H.5
Prieto, J.G.6
-
97
-
-
17844365262
-
The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin
-
Merino G., Jonker J.W., Wagenaar E., van Herwaarden A.E., and Schinkel A.H. The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin. Mol. Pharmacol. 67 (2005) 1758-1764
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 1758-1764
-
-
Merino, G.1
Jonker, J.W.2
Wagenaar, E.3
van Herwaarden, A.E.4
Schinkel, A.H.5
-
98
-
-
0032895533
-
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes
-
Miyake K., Mickley L., Litman T., Zhan Z., Robey R., Cristensen B., Brangi M., Greenberger L., Dean M., Fojo T., and Bates S.E. Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. Cancer Res. 59 (1999) 8-13
-
(1999)
Cancer Res.
, vol.59
, pp. 8-13
-
-
Miyake, K.1
Mickley, L.2
Litman, T.3
Zhan, Z.4
Robey, R.5
Cristensen, B.6
Brangi, M.7
Greenberger, L.8
Dean, M.9
Fojo, T.10
Bates, S.E.11
-
99
-
-
19944431266
-
Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin
-
Miyoshi M., Nadai M., Nitta A., Ueyama J., Shimizu A., Takagi K., Nabeshima T., Takagi K., Saito K., and Hasegawa T. Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin. Eur. J. Pharmacol. 507 (2005) 229-237
-
(2005)
Eur. J. Pharmacol.
, vol.507
, pp. 229-237
-
-
Miyoshi, M.1
Nadai, M.2
Nitta, A.3
Ueyama, J.4
Shimizu, A.5
Takagi, K.6
Nabeshima, T.7
Takagi, K.8
Saito, K.9
Hasegawa, T.10
-
100
-
-
4143107239
-
Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (e3040) sulfate in Breast Cancer Resistance Protein (BCRP1/ABCG2) knockout mice
-
Mizuno N., Suzuki M., Kusuhara H., Suzuki H., Takeuchi K., Niwa T., Jonker J.W., and Sugiyama Y. Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (e3040) sulfate in Breast Cancer Resistance Protein (BCRP1/ABCG2) knockout mice. Drug Metab. Dispos. 32 (2004) 898-901
-
(2004)
Drug Metab. Dispos.
, vol.32
, pp. 898-901
-
-
Mizuno, N.1
Suzuki, M.2
Kusuhara, H.3
Suzuki, H.4
Takeuchi, K.5
Niwa, T.6
Jonker, J.W.7
Sugiyama, Y.8
-
101
-
-
33644914487
-
Flavonoid-drug interactions: effects of flavonoids on ABC transporters
-
Morris M.E., and Zhang S. Flavonoid-drug interactions: effects of flavonoids on ABC transporters. Life Sci. 78 (2006) 2116-2130
-
(2006)
Life Sci.
, vol.78
, pp. 2116-2130
-
-
Morris, M.E.1
Zhang, S.2
-
102
-
-
34247213414
-
Phase I/II trial of a P-glycoprotein inhibitor, Zosuquidar·3HCl trihydrochloride (LY335979), given orally in combination with the CHOP regimen in patients with non-Hodgkin's lymphoma
-
Morschhauser F., Zinzani P.L., Burgess M., Sloots L., Bouafia F., and Dumontet C. Phase I/II trial of a P-glycoprotein inhibitor, Zosuquidar·3HCl trihydrochloride (LY335979), given orally in combination with the CHOP regimen in patients with non-Hodgkin's lymphoma. Leuk. Lymphoma 48 (2007) 708-715
-
(2007)
Leuk. Lymphoma
, vol.48
, pp. 708-715
-
-
Morschhauser, F.1
Zinzani, P.L.2
Burgess, M.3
Sloots, L.4
Bouafia, F.5
Dumontet, C.6
-
103
-
-
4143098211
-
Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage
-
Neff M.W., Robertson K.R., Wong A.K., Safra N., Broman K.W., Slatkin M., Mealey K.L., and Pedersen N.C. Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage. Proc. Natl. Acad. Sci. U S A 101 (2004) 11725-11730
-
(2004)
Proc. Natl. Acad. Sci. U S A
, vol.101
, pp. 11725-11730
-
-
Neff, M.W.1
Robertson, K.R.2
Wong, A.K.3
Safra, N.4
Broman, K.W.5
Slatkin, M.6
Mealey, K.L.7
Pedersen, N.C.8
-
104
-
-
13444250882
-
Functional analysis of dog multidrug resistance-associated protein 2 (mrp2) in comparison with rat mrp2
-
Ninomiya M., Ito K., and Horie T. Functional analysis of dog multidrug resistance-associated protein 2 (mrp2) in comparison with rat mrp2. Drug Metab. Dispos. 33 (2005) 225-232
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 225-232
-
-
Ninomiya, M.1
Ito, K.2
Horie, T.3
-
105
-
-
0032987025
-
Effect of itraconazole on the pharmacokinetics of digoxin in guinea pigs
-
Nishihara K., Hibino J., Kotaki H., Sawada Y., and Iga T. Effect of itraconazole on the pharmacokinetics of digoxin in guinea pigs. Biopharm. Drug Dispos. 20 (1999) 145-149
-
(1999)
Biopharm. Drug Dispos.
, vol.20
, pp. 145-149
-
-
Nishihara, K.1
Hibino, J.2
Kotaki, H.3
Sawada, Y.4
Iga, T.5
-
106
-
-
0034705867
-
Safety of selamectin in dogs
-
Novotny M.J., Krautmann M.J., Ehrhart J.C., Godin C.S., Evans E.I., McCall J.W., Sun F., Rowan T.G., and Jernigan A.D. Safety of selamectin in dogs. Vet. Parasitol. 91 (2000) 377-391
-
(2000)
Vet. Parasitol.
, vol.91
, pp. 377-391
-
-
Novotny, M.J.1
Krautmann, M.J.2
Ehrhart, J.C.3
Godin, C.S.4
Evans, E.I.5
McCall, J.W.6
Sun, F.7
Rowan, T.G.8
Jernigan, A.D.9
-
107
-
-
0041524278
-
Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1)
-
Nunoya K., Grant C.E., Zhang D., Cole S.P.C., and Deeley R.G. Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1). Drug Metab. Dispos. 31 (2003) 1016-1026
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 1016-1026
-
-
Nunoya, K.1
Grant, C.E.2
Zhang, D.3
Cole, S.P.C.4
Deeley, R.G.5
-
108
-
-
0033851888
-
Molecular analysis of multidrug resistance in feline lymphoma cells
-
Okai Y., Nakamura N., Matsushiro H., Kato H., Setoguchi A., Yazawa M., Okuda M., Watari T., Hasegawa A., and Tsujimoto H. Molecular analysis of multidrug resistance in feline lymphoma cells. Am. J. Vet. Res. 61 (2000) 1122-1127
-
(2000)
Am. J. Vet. Res.
, vol.61
, pp. 1122-1127
-
-
Okai, Y.1
Nakamura, N.2
Matsushiro, H.3
Kato, H.4
Setoguchi, A.5
Yazawa, M.6
Okuda, M.7
Watari, T.8
Hasegawa, A.9
Tsujimoto, H.10
-
109
-
-
0025375508
-
ATP-dependent efflux of GSSG and GS-conjugate from isolated rat hepatocytes
-
Oude Elferink R.P., Ottenhoff R., Liefting W.G., Schoemaker B., Groen A.K., and Jansen P.L. ATP-dependent efflux of GSSG and GS-conjugate from isolated rat hepatocytes. Am. J. Physiol. 258 (1990) G699-G706
-
(1990)
Am. J. Physiol.
, vol.258
-
-
Oude Elferink, R.P.1
Ottenhoff, R.2
Liefting, W.G.3
Schoemaker, B.4
Groen, A.K.5
Jansen, P.L.6
-
110
-
-
0029082150
-
Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport
-
Oude Elferink R.P.J., Meijer D.K.F., Kuipers F., Jansen P.L.M., Groen A.K., and Groothuis G.M.M. Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport. Biochim. Biophys. Acta (BBA) - Rev. Biomembr. 1241 (1995) 215-268
-
(1995)
Biochim. Biophys. Acta (BBA) - Rev. Biomembr.
, vol.1241
, pp. 215-268
-
-
Oude Elferink, R.P.J.1
Meijer, D.K.F.2
Kuipers, F.3
Jansen, P.L.M.4
Groen, A.K.5
Groothuis, G.M.M.6
-
111
-
-
2342628461
-
Dermal safety study with imidacloprid/moxidectin topical solution in the ivermectin-sensitive collie
-
Paul A.J., Hutchens D.E., Firkins L.D., and Borgstrom M. Dermal safety study with imidacloprid/moxidectin topical solution in the ivermectin-sensitive collie. Vet. Parasitol. 121 (2004) 285-291
-
(2004)
Vet. Parasitol.
, vol.121
, pp. 285-291
-
-
Paul, A.J.1
Hutchens, D.E.2
Firkins, L.D.3
Borgstrom, M.4
-
112
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
Paulusma C.C., Bosma P.J., Zaman G.J., Bakker C.T., Otter M., Scheffer G.L., Scheper R.J., Borst P., and Oude Elferink R.P. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science 271 (1996) 1126-1128
-
(1996)
Science
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.3
Bakker, C.T.4
Otter, M.5
Scheffer, G.L.6
Scheper, R.J.7
Borst, P.8
Oude Elferink, R.P.9
-
113
-
-
4344561031
-
Immunohistochemical detection of growth hormone (GH) in canine hepatoid gland tumors
-
Petterino C., Martini M., and Castagnaro M. Immunohistochemical detection of growth hormone (GH) in canine hepatoid gland tumors. J. Vet. Med. Sci. 66 (2004) 569-572
-
(2004)
J. Vet. Med. Sci.
, vol.66
, pp. 569-572
-
-
Petterino, C.1
Martini, M.2
Castagnaro, M.3
-
114
-
-
33745726825
-
Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): influence of flavonoids and role in milk secretion in sheep
-
Pulido M.M., Molina A.J., Merino G., Mendoza G., Prieto J.G., and Alvarez A.I. Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): influence of flavonoids and role in milk secretion in sheep. J. Vet. Pharmacol. Ther. 29 (2006) 279-287
-
(2006)
J. Vet. Pharmacol. Ther.
, vol.29
, pp. 279-287
-
-
Pulido, M.M.1
Molina, A.J.2
Merino, G.3
Mendoza, G.4
Prieto, J.G.5
Alvarez, A.I.6
-
115
-
-
0036051394
-
Efficacy and pharmacokinetics of enrofloxacin and flunixin meglumine for treatment of cows with experimentally induced Escherichia coli mastitis
-
Rantala M., Kaartinen L., Valimaki E., Stryrman M., Hiekkaranta M., Niemi A., Saari L., and Pyorala S. Efficacy and pharmacokinetics of enrofloxacin and flunixin meglumine for treatment of cows with experimentally induced Escherichia coli mastitis. J. Vet. Pharmacol. Ther. 25 (2002) 251-258
-
(2002)
J. Vet. Pharmacol. Ther.
, vol.25
, pp. 251-258
-
-
Rantala, M.1
Kaartinen, L.2
Valimaki, E.3
Stryrman, M.4
Hiekkaranta, M.5
Niemi, A.6
Saari, L.7
Pyorala, S.8
-
116
-
-
0030820008
-
Recent studies on the effects of tiamulin and monensin on hepatic cytochrome P450 activities in chickens and turkeys
-
Ratz V., Laczay P., Mora Z., Csiko G., Monostori K., Vereczkey L., Lehel J., and Semjen G. Recent studies on the effects of tiamulin and monensin on hepatic cytochrome P450 activities in chickens and turkeys. J. Vet. Pharmacol. Ther. 20 (1997) 415-418
-
(1997)
J. Vet. Pharmacol. Ther.
, vol.20
, pp. 415-418
-
-
Ratz, V.1
Laczay, P.2
Mora, Z.3
Csiko, G.4
Monostori, K.5
Vereczkey, L.6
Lehel, J.7
Semjen, G.8
-
117
-
-
0023196635
-
Pharmacokinetics and interactions of digoxin with phenobarbital in dogs
-
Ravis W.R., Pedersoli W.M., and Turco J.D. Pharmacokinetics and interactions of digoxin with phenobarbital in dogs. Am. J. Vet. Res. 48 (1987) 1244-1249
-
(1987)
Am. J. Vet. Res.
, vol.48
, pp. 1244-1249
-
-
Ravis, W.R.1
Pedersoli, W.M.2
Turco, J.D.3
-
118
-
-
0026536295
-
The effects of cardiac transplantation and cyclosporine therapy on digoxin pharmacokinetics
-
Robieux I., Dorian P., Klein J., Chung D., Zborowska-Sluis D., Ogilvie R., and Koren G. The effects of cardiac transplantation and cyclosporine therapy on digoxin pharmacokinetics. J. Clin. Pharmacol. 32 (1992) 338-343
-
(1992)
J. Clin. Pharmacol.
, vol.32
, pp. 338-343
-
-
Robieux, I.1
Dorian, P.2
Klein, J.3
Chung, D.4
Zborowska-Sluis, D.5
Ogilvie, R.6
Koren, G.7
-
119
-
-
0038112049
-
Review of the pharmacokinetics, interactions and adverse reactions of cyclosporine in people, dogs and cats
-
Robson D. Review of the pharmacokinetics, interactions and adverse reactions of cyclosporine in people, dogs and cats. Vet. Rec. 152 (2003) 739-748
-
(2003)
Vet. Rec.
, vol.152
, pp. 739-748
-
-
Robson, D.1
-
120
-
-
0142091295
-
Physiological regulation of P-glycoprotein, MRP1, MRP2 and cytochrome P450 3A2 during rat ontogeny
-
Rosati A., Maniori S., Decorti G., Candussio L., Giraldi T., and Bartoli F. Physiological regulation of P-glycoprotein, MRP1, MRP2 and cytochrome P450 3A2 during rat ontogeny. Dev. Growth Differ. 45 (2003) 377-387
-
(2003)
Dev. Growth Differ.
, vol.45
, pp. 377-387
-
-
Rosati, A.1
Maniori, S.2
Decorti, G.3
Candussio, L.4
Giraldi, T.5
Bartoli, F.6
-
121
-
-
0038421230
-
Role of P-glycoprotein in pharmacokinetics and drug interactions of digoxin and beta-methyldigoxin in rats
-
Funakoshi S., Murakami T., Yumoto R., Kiribayashi Y., and Takano M. Role of P-glycoprotein in pharmacokinetics and drug interactions of digoxin and beta-methyldigoxin in rats. J. Pharm. Sci. 92 (2003) 1455-1463
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 1455-1463
-
-
Funakoshi, S.1
Murakami, T.2
Yumoto, R.3
Kiribayashi, Y.4
Takano, M.5
-
122
-
-
0842330472
-
Loperamide toxicity in a collie with the MDR1 mutation associated with ivermectin sensitivity
-
Sartor L.L., Bentjen S.A., Trepanier L., and Mealey K.L. Loperamide toxicity in a collie with the MDR1 mutation associated with ivermectin sensitivity. J. Vet. Intern. Med. 18 (2004) 117-118
-
(2004)
J. Vet. Intern. Med.
, vol.18
, pp. 117-118
-
-
Sartor, L.L.1
Bentjen, S.A.2
Trepanier, L.3
Mealey, K.L.4
-
123
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
-
Schinkel A.H., Mayer U., Wagenaar E., Mol C.A., van Deemter L., Smit J.J., van der Valk M.A., Voordouw A.C., Spits H., van Tellingen O., Zijlmans J.M., Fibbe W.E., and Borst P. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc. Natl. Acad. Sci. U S A 94 (1997) 4028-4033
-
(1997)
Proc. Natl. Acad. Sci. U S A
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.H.1
Mayer, U.2
Wagenaar, E.3
Mol, C.A.4
van Deemter, L.5
Smit, J.J.6
van der Valk, M.A.7
Voordouw, A.C.8
Spits, H.9
van Tellingen, O.10
Zijlmans, J.M.11
Fibbe, W.E.12
Borst, P.13
-
124
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel A.H., Smit J.J., van Tellingen O., Beijnen J.H., Wagenaar E., van Deemter L., Mol C.A., van der Valk M.A., Robanus-Maandag E.C., te Riele H.P., et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77 (1994) 491-502
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
van Deemter, L.6
Mol, C.A.7
van der Valk, M.A.8
Robanus-Maandag, E.C.9
te Riele, H.P.10
-
125
-
-
33846081034
-
P-glycoprotein-mediated transport of oxytetracycline in the Caco-2 cell model
-
Schrickx J., and Fink-Gremmels J. P-glycoprotein-mediated transport of oxytetracycline in the Caco-2 cell model. J. Vet. Pharmacol. Ther. 30 (2007) 25-31
-
(2007)
J. Vet. Pharmacol. Ther.
, vol.30
, pp. 25-31
-
-
Schrickx, J.1
Fink-Gremmels, J.2
-
126
-
-
33847165756
-
Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters
-
Schrickx J.A., and Fink-Gremmels J. Danofloxacin-mesylate is a substrate for ATP-dependent efflux transporters. Br. J. Pharmacol. 150 (2007) 463-469
-
(2007)
Br. J. Pharmacol.
, vol.150
, pp. 463-469
-
-
Schrickx, J.A.1
Fink-Gremmels, J.2
-
127
-
-
43049164659
-
-
Schrickx, J.A., 2006. ABC-transporters in the pig. Ph.D. thesis Veterinary Pharmacology, Pharmacy and Toxicology (Utrecht University, Utrecht).
-
Schrickx, J.A., 2006. ABC-transporters in the pig. Ph.D. thesis Veterinary Pharmacology, Pharmacy and Toxicology (Utrecht University, Utrecht).
-
-
-
-
128
-
-
21744461919
-
Breast Cancer Resistance Protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides
-
Sesink A.L.A., Arts I.C.W., de Boer V.C.J., Breedveld P., Schellens J.H.M., Hollman P.C.H., and Russel F.G.M. Breast Cancer Resistance Protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides. Mol. Pharmacol. 67 (2005) 1999-2006
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 1999-2006
-
-
Sesink, A.L.A.1
Arts, I.C.W.2
de Boer, V.C.J.3
Breedveld, P.4
Schellens, J.H.M.5
Hollman, P.C.H.6
Russel, F.G.M.7
-
129
-
-
0031746770
-
Pharmacokinetics and penetration of danofloxacin from the blood into the milk of cows
-
Shem-Tov M., Rav-Hon O., Ziv G., Lavi E., Glickman A., and Saran A. Pharmacokinetics and penetration of danofloxacin from the blood into the milk of cows. J. Vet. Pharm. Ther. 21 (1998) 209-213
-
(1998)
J. Vet. Pharm. Ther.
, vol.21
, pp. 209-213
-
-
Shem-Tov, M.1
Rav-Hon, O.2
Ziv, G.3
Lavi, E.4
Glickman, A.5
Saran, A.6
-
130
-
-
0031746770
-
Pharmacokinetics and penetration of danofloxacin from the blood into the milk of cows
-
Shem-Tov M., Rav-Hon O., Ziv G., Lavi E., Glickman A., and Saran A. Pharmacokinetics and penetration of danofloxacin from the blood into the milk of cows. J. Vet. Pharmacol. Ther. 21 (1998) 209-213
-
(1998)
J. Vet. Pharmacol. Ther.
, vol.21
, pp. 209-213
-
-
Shem-Tov, M.1
Rav-Hon, O.2
Ziv, G.3
Lavi, E.4
Glickman, A.5
Saran, A.6
-
131
-
-
4644353268
-
Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats
-
Shimizu A., Miyoshi M., Sugie M., Ueyama J., Yamaguchi T., Sasaki T., Takagi K., Jin M., Miyamoto K., Tsuji A., and Hasegawa T. Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats. Eur. J. Pharmacol. 501 (2004) 151-159
-
(2004)
Eur. J. Pharmacol.
, vol.501
, pp. 151-159
-
-
Shimizu, A.1
Miyoshi, M.2
Sugie, M.3
Ueyama, J.4
Yamaguchi, T.5
Sasaki, T.6
Takagi, K.7
Jin, M.8
Miyamoto, K.9
Tsuji, A.10
Hasegawa, T.11
-
132
-
-
0031837161
-
Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted
-
Smit J.W., Schinkel A.H., Weert B., and Meijer D.K. Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted. Br. J. Pharmacol. 124 (1998) 416-424
-
(1998)
Br. J. Pharmacol.
, vol.124
, pp. 416-424
-
-
Smit, J.W.1
Schinkel, A.H.2
Weert, B.3
Meijer, D.K.4
-
133
-
-
0034604707
-
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping
-
Smith A.J., van Helvoort A., van Meer G., Szabo K., Welker E., Szakacs G., Varadi A., Sarkadi B., and Borst P. MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping. J. Biol. Chem. 275 (2000) 23530-23539
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23530-23539
-
-
Smith, A.J.1
van Helvoort, A.2
van Meer, G.3
Szabo, K.4
Welker, E.5
Szakacs, G.6
Varadi, A.7
Sarkadi, B.8
Borst, P.9
-
134
-
-
0024981660
-
Gastrointestinal secretion of ciprofloxacin. Evaluation of the charcoal model for investigations in healthy volunteers
-
Sorgel F., Naber K.G., Jaehde U., Reiter A., Seelmann R., and Sigl G. Gastrointestinal secretion of ciprofloxacin. Evaluation of the charcoal model for investigations in healthy volunteers. Am. J. Med. 87 (1989) 62S-65S
-
(1989)
Am. J. Med.
, vol.87
-
-
Sorgel, F.1
Naber, K.G.2
Jaehde, U.3
Reiter, A.4
Seelmann, R.5
Sigl, G.6
-
135
-
-
12644278301
-
Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
-
Sparreboom A., van Asperen J., Mayer U., Schinkel A.H., Smit J.W., Meijer D.K., Borst P., Nooijen W.J., Beijnen J.H., and Van Tellingen O. Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine. Proc. Natl. Acad. Sci. U S A 94 (1997) 2031-2035
-
(1997)
Proc. Natl. Acad. Sci. U S A
, vol.94
, pp. 2031-2035
-
-
Sparreboom, A.1
van Asperen, J.2
Mayer, U.3
Schinkel, A.H.4
Smit, J.W.5
Meijer, D.K.6
Borst, P.7
Nooijen, W.J.8
Beijnen, J.H.9
Van Tellingen, O.10
-
136
-
-
0031922587
-
Characterization of canine MDR1 mRNA: its abundance in drug resistant cell lines and in vivo
-
Steingold S.F., Sharp N.J., McGahan M.C., Hughes C.S., Dunn S.E., and Page R.L. Characterization of canine MDR1 mRNA: its abundance in drug resistant cell lines and in vivo. Anticancer. Res. 18 (1998) 393-400
-
(1998)
Anticancer. Res.
, vol.18
, pp. 393-400
-
-
Steingold, S.F.1
Sharp, N.J.2
McGahan, M.C.3
Hughes, C.S.4
Dunn, S.E.5
Page, R.L.6
-
137
-
-
0030775395
-
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells
-
Stride B.D., Grant C.E., Loe D.W., Hipfner D.R., Cole S.P.C., and Deeley R.G. Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. Mol. Pharmacol. 52 (1997) 344-353
-
(1997)
Mol. Pharmacol.
, vol.52
, pp. 344-353
-
-
Stride, B.D.1
Grant, C.E.2
Loe, D.W.3
Hipfner, D.R.4
Cole, S.P.C.5
Deeley, R.G.6
-
138
-
-
36849004988
-
Predictive value of multidrug resistance proteins and cellular drug resistance in childhood relapsed acute lymphoblastic leukemia
-
Styczynski J., Wysocki M., Debski R., Czyzewski K., Kolodziej B., Rafinska B., Kubicka M., Koltan S., Koltan A., Pogorzala M., Kurylak A., Olszewska-Slonina D., Balwierz W., Juraszewska E., Wieczorek M., Olejnik I., Krawczuk-Rybak M., Kuzmicz M., Kowalczyk J., Stefaniak J., Badowska W., Sonta-Jakimczyk D., Szczepanski T., Matysiak M., Malinowska I., Stanczak E., Wachowiak J., Konatkowska B., Gil L., Balcerska A., and Maciejka-Kapuscinska L. Predictive value of multidrug resistance proteins and cellular drug resistance in childhood relapsed acute lymphoblastic leukemia. J. Cancer Res. Clin. Oncol. 133 (2007) 875-893
-
(2007)
J. Cancer Res. Clin. Oncol.
, vol.133
, pp. 875-893
-
-
Styczynski, J.1
Wysocki, M.2
Debski, R.3
Czyzewski, K.4
Kolodziej, B.5
Rafinska, B.6
Kubicka, M.7
Koltan, S.8
Koltan, A.9
Pogorzala, M.10
Kurylak, A.11
Olszewska-Slonina, D.12
Balwierz, W.13
Juraszewska, E.14
Wieczorek, M.15
Olejnik, I.16
Krawczuk-Rybak, M.17
Kuzmicz, M.18
Kowalczyk, J.19
Stefaniak, J.20
Badowska, W.21
Sonta-Jakimczyk, D.22
Szczepanski, T.23
Matysiak, M.24
Malinowska, I.25
Stanczak, E.26
Wachowiak, J.27
Konatkowska, B.28
Gil, L.29
Balcerska, A.30
Maciejka-Kapuscinska, L.31
more..
-
139
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
Suzuki M., Suzuki H., Sugimoto Y., and Sugiyama Y. ABCG2 transports sulfated conjugates of steroids and xenobiotics. J. Biol. Chem. 278 (2003) 22644-22649
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 22644-22649
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
140
-
-
34250763702
-
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport
-
Suzuyama N., Katoh M., Takeuchi T., Yoshitomi S., Higuchi T., Asashi S., and Yokoi T. Species differences of inhibitory effects on P-glycoprotein-mediated drug transport. J. Pharm. Sci. 96 (2007) 1609-1618
-
(2007)
J. Pharm. Sci.
, vol.96
, pp. 1609-1618
-
-
Suzuyama, N.1
Katoh, M.2
Takeuchi, T.3
Yoshitomi, S.4
Higuchi, T.5
Asashi, S.6
Yokoi, T.7
-
141
-
-
5144226566
-
Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells
-
Szakacs G., Annereau J.P., Lababidi S., Shankavaram U., Arciello A., Bussey K.J., Reinhold W., Guo Y., Kruh G.D., Reimers M., Weinstein J.N., and Gottesman M.M. Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells. Cancer Cell 6 (2004) 129-137
-
(2004)
Cancer Cell
, vol.6
, pp. 129-137
-
-
Szakacs, G.1
Annereau, J.P.2
Lababidi, S.3
Shankavaram, U.4
Arciello, A.5
Bussey, K.J.6
Reinhold, W.7
Guo, Y.8
Kruh, G.D.9
Reimers, M.10
Weinstein, J.N.11
Gottesman, M.M.12
-
142
-
-
1542316767
-
Biochemical background of toxic interaction between tiamulin and monensin
-
Szucs G., Tamasi V., Laczay P., and Monostory K. Biochemical background of toxic interaction between tiamulin and monensin. Chem. Biol. Interact. 147 (2004) 151-161
-
(2004)
Chem. Biol. Interact.
, vol.147
, pp. 151-161
-
-
Szucs, G.1
Tamasi, V.2
Laczay, P.3
Monostory, K.4
-
143
-
-
0037134795
-
Functional analysis of MRP1 cloned from bovine
-
Taguchi Y., Saeki K., and Komano T. Functional analysis of MRP1 cloned from bovine. FEBS Lett. 521 (2002) 211-213
-
(2002)
FEBS Lett.
, vol.521
, pp. 211-213
-
-
Taguchi, Y.1
Saeki, K.2
Komano, T.3
-
144
-
-
33745632043
-
Establishment and characterization of the transformants stably-expressing MDR1 derived from various animal species in LLC-PK1
-
Takeuchi T., Yoshitomi S., Higuchi T., Ikemoto K., Niwa S., Ebihara T., Katoh M., Yokoi T., and Asahi S. Establishment and characterization of the transformants stably-expressing MDR1 derived from various animal species in LLC-PK1. Pharm. Res. 23 (2006) 1460-1472
-
(2006)
Pharm. Res.
, vol.23
, pp. 1460-1472
-
-
Takeuchi, T.1
Yoshitomi, S.2
Higuchi, T.3
Ikemoto, K.4
Niwa, S.5
Ebihara, T.6
Katoh, M.7
Yokoi, T.8
Asahi, S.9
-
145
-
-
9644282955
-
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice
-
Tanaka Y., Slitt A.L., Leazer T.M., Maher J.M., and Klaassen C.D. Tissue
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.326
, pp. 181-187
-
-
Tanaka, Y.1
Slitt, A.L.2
Leazer, T.M.3
Maher, J.M.4
Klaassen, C.D.5
-
146
-
-
34548812849
-
Cellular characterization of multidrug resistance P-glycoprotein, alpha fetoprotein, and neovascular endothelium-associated antigens in canine hepatocellular carcinoma and cirrhotic liver
-
Tashbaeva R.E., Hwang D.N., Song G.S., Choi N.H., Lee J.H., Lyoo Y.S., Lee S.J., Jung D.I., Kim H.Y., and Sur J.H. Cellular characterization of multidrug resistance P-glycoprotein, alpha fetoprotein, and neovascular endothelium-associated antigens in canine hepatocellular carcinoma and cirrhotic liver. Vet. Pathol. 44 (2007) 600-606
-
(2007)
Vet. Pathol.
, vol.44
, pp. 600-606
-
-
Tashbaeva, R.E.1
Hwang, D.N.2
Song, G.S.3
Choi, N.H.4
Lee, J.H.5
Lyoo, Y.S.6
Lee, S.J.7
Jung, D.I.8
Kim, H.Y.9
Sur, J.H.10
-
147
-
-
27544483787
-
Functional assessment of multiple p-glycoprotein (p-gp) probe substrates: influence of cell line and modulator concentration on p-gp activity
-
Taub M.E., Podila L., Ely D., and Almeida I. Functional assessment of multiple p-glycoprotein (p-gp) probe substrates: influence of cell line and modulator concentration on p-gp activity. Drug Metab. Dispos. 33 (2005) 1679-1687
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 1679-1687
-
-
Taub, M.E.1
Podila, L.2
Ely, D.3
Almeida, I.4
-
148
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F., Tsuruo T., Hamada H., Gottesman M.M., Pastan I., and Willingham M.C. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. U S A 84 (1987) 7735-7738
-
(1987)
Proc. Natl. Acad. Sci. U S A
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
149
-
-
0020040677
-
The physiological disposition and metabolism of enalapril maleate in laboratory animals
-
Tocco D.J., deLuna F.A., Duncan A.E., Vassil T.C., and Ulm E.H. The physiological disposition and metabolism of enalapril maleate in laboratory animals. Drug Metab. Dispos. 10 (1982) 15-19
-
(1982)
Drug Metab. Dispos.
, vol.10
, pp. 15-19
-
-
Tocco, D.J.1
deLuna, F.A.2
Duncan, A.E.3
Vassil, T.C.4
Ulm, E.H.5
-
150
-
-
34548071672
-
ABCG2 expression is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma
-
Tsunoda S., Okumura T., Ito T., Kondo K., Ortiz C., Tanaka E., Watanabe G., Itami A., Sakai Y., and Shimada Y. ABCG2 expression is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma. Oncology 71 (2006) 251-258
-
(2006)
Oncology
, vol.71
, pp. 251-258
-
-
Tsunoda, S.1
Okumura, T.2
Ito, T.3
Kondo, K.4
Ortiz, C.5
Tanaka, E.6
Watanabe, G.7
Itami, A.8
Sakai, Y.9
Shimada, Y.10
-
151
-
-
24044470370
-
Multidrug resistance in AIDS-related lymphoma
-
Tulpule A. Multidrug resistance in AIDS-related lymphoma. Curr. Opin. Oncol. 17 (2005) 466-468
-
(2005)
Curr. Opin. Oncol.
, vol.17
, pp. 466-468
-
-
Tulpule, A.1
-
152
-
-
0033952456
-
Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption
-
Uhr M., Steckler T., Yassouridis A., and Holsboer F. Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption. Neuropsychopharmacology 22 (2000) 380-387
-
(2000)
Neuropsychopharmacology
, vol.22
, pp. 380-387
-
-
Uhr, M.1
Steckler, T.2
Yassouridis, A.3
Holsboer, F.4
-
153
-
-
26444539011
-
Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions
-
van de Water F.M., Masereeuw R., and Russel F.G. Function and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions. Drug. Metab. Rev. 37 (2005) 443-471
-
(2005)
Drug. Metab. Rev.
, vol.37
, pp. 443-471
-
-
van de Water, F.M.1
Masereeuw, R.2
Russel, F.G.3
-
154
-
-
0022610102
-
Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line
-
Van der Bliek A.M., Van der Velde-Koerts T., Ling V., and Borst P. Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line. Mol. Cell Biol. 6 (1986) 1671-1678
-
(1986)
Mol. Cell Biol.
, vol.6
, pp. 1671-1678
-
-
Van der Bliek, A.M.1
Van der Velde-Koerts, T.2
Ling, V.3
Borst, P.4
-
155
-
-
0037872761
-
Function of the ABC transporters, P-glycoprotein, multidrug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia
-
van der Pol M.A., Broxterman H.J., Pater J.M., Feller N., van der Maas M., Weijers G.W., Scheffer G.L., Allen J.D., Scheper R.J., van Loevezijn A., Ossenkoppele G.J., and Schuurhuis G.J. Function of the ABC transporters, P-glycoprotein, multidrug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia. Haematologica 88 (2003) 134-147
-
(2003)
Haematologica
, vol.88
, pp. 134-147
-
-
van der Pol, M.A.1
Broxterman, H.J.2
Pater, J.M.3
Feller, N.4
van der Maas, M.5
Weijers, G.W.6
Scheffer, G.L.7
Allen, J.D.8
Scheper, R.J.9
van Loevezijn, A.10
Ossenkoppele, G.J.11
Schuurhuis, G.J.12
-
156
-
-
0141919551
-
The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
van Herwaarden A.E., Jonker J.W., Wagenaar E., Brinkhuis R.F., Schellens J.H., Beijnen J.H., and Schinkel A.H. The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Cancer Res. 63 (2003) 6447-6452
-
(2003)
Cancer Res.
, vol.63
, pp. 6447-6452
-
-
van Herwaarden, A.E.1
Jonker, J.W.2
Wagenaar, E.3
Brinkhuis, R.F.4
Schellens, J.H.5
Beijnen, J.H.6
Schinkel, A.H.7
-
157
-
-
29744441900
-
Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk
-
van Herwaarden A.E., Wagenaar E., Karnekamp B., Merino G., Jonker J.W., and Schinkel A.H. Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk. Carcinogenesis 27 (2006) 123-130
-
(2006)
Carcinogenesis
, vol.27
, pp. 123-130
-
-
van Herwaarden, A.E.1
Wagenaar, E.2
Karnekamp, B.3
Merino, G.4
Jonker, J.W.5
Schinkel, A.H.6
-
158
-
-
0030804291
-
Assignment of the canalicular multispecific organic anion transporter gene (CMOAT) to human chromosome 10q24 and mouse chromosome 19D2 by fluorescent in situ hybridization
-
van Kuijck M.A., Kool M., Merkx G.F., Geurts van Kessel A., Bindels R.J., Deen P.M., and Van Os C.H. Assignment of the canalicular multispecific organic anion transporter gene (CMOAT) to human chromosome 10q24 and mouse chromosome 19D2 by fluorescent in situ hybridization. Cytogenet. Cel. Genet. 77 (1997) 285-287
-
(1997)
Cytogenet. Cel. Genet.
, vol.77
, pp. 285-287
-
-
van Kuijck, M.A.1
Kool, M.2
Merkx, G.F.3
Geurts van Kessel, A.4
Bindels, R.J.5
Deen, P.M.6
Van Os, C.H.7
-
159
-
-
0038813439
-
Drug uptake systems in liver and kidney
-
van Montfoort J.E., Hagenbuch B., Groothuis G.M., Koepsell H., Meier P.J., and Meijer D.K. Drug uptake systems in liver and kidney. Curr. Drug. Metab. 4 (2003) 185-211
-
(2003)
Curr. Drug. Metab.
, vol.4
, pp. 185-211
-
-
van Montfoort, J.E.1
Hagenbuch, B.2
Groothuis, G.M.3
Koepsell, H.4
Meier, P.J.5
Meijer, D.K.6
-
160
-
-
0032848316
-
P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil
-
Verschraagen M., Koks C.H.W., Schellens J.H.M., and Beijnen J.H. P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil. Pharm. Res. 40 (1999) 301-306
-
(1999)
Pharm. Res.
, vol.40
, pp. 301-306
-
-
Verschraagen, M.1
Koks, C.H.W.2
Schellens, J.H.M.3
Beijnen, J.H.4
-
161
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy
-
Wacher V.J., Wu C.Y., and Benet L.Z. Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol. Carcinog. 13 (1995) 129-134
-
(1995)
Mol. Carcinog.
, vol.13
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.Y.2
Benet, L.Z.3
-
162
-
-
33845383376
-
Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors
-
Wang H., Wu X., Hudkins K., Mikheev A., Zhang H., Gupta A., Unadkat J.D., and Mao Q. Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors. Am. J. Physiol. Endocrinol. Metab. 291 (2006) E1295-E1304
-
(2006)
Am. J. Physiol. Endocrinol. Metab.
, vol.291
-
-
Wang, H.1
Wu, X.2
Hudkins, K.3
Mikheev, A.4
Zhang, H.5
Gupta, A.6
Unadkat, J.D.7
Mao, Q.8
-
163
-
-
0036175308
-
Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo
-
Yamaguchi H., Yano I., Saito H., and Inui K.-i. Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo. J. Pharmacol. Exp. Ther. 300 (2002) 1063-1069
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 1063-1069
-
-
Yamaguchi, H.1
Yano, I.2
Saito, H.3
Inui, K.-i.4
-
164
-
-
33644682781
-
Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse
-
Zaher H., Khan A.A., Palandra J., Brayman T.G., Yu L., and Ware J.A. Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse. Mol. Pharm. 3 (2006) 55-61
-
(2006)
Mol. Pharm.
, vol.3
, pp. 55-61
-
-
Zaher, H.1
Khan, A.A.2
Palandra, J.3
Brayman, T.G.4
Yu, L.5
Ware, J.A.6
-
165
-
-
22944456884
-
Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1
-
Zamek-Gliszczynski M.J., Hoffmaster K.A., Tian X., Zhao R., Polli J.W., Humphreys J.E., Webster L.O., Bridges A.S., Kalvass J.C., and Brouwer K.L. Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1. Drug. Metab. Dispos. 33 (2005) 1158-1165
-
(2005)
Drug. Metab. Dispos.
, vol.33
, pp. 1158-1165
-
-
Zamek-Gliszczynski, M.J.1
Hoffmaster, K.A.2
Tian, X.3
Zhao, R.4
Polli, J.W.5
Humphreys, J.E.6
Webster, L.O.7
Bridges, A.S.8
Kalvass, J.C.9
Brouwer, K.L.10
-
166
-
-
33751104475
-
The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice
-
Zamek-Gliszczynski M.J., Nezasa K., Tian X., Kalvass J.C., Patel N.J., Raub T.J., and Brouwer K.L. The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice. Mol. Pharmacol. 70 (2006) 2127-2133
-
(2006)
Mol. Pharmacol.
, vol.70
, pp. 2127-2133
-
-
Zamek-Gliszczynski, M.J.1
Nezasa, K.2
Tian, X.3
Kalvass, J.C.4
Patel, N.J.5
Raub, T.J.6
Brouwer, K.L.7
-
168
-
-
0027361042
-
Dubin-Johnson and Rotor syndromes: molecular basis and pathogenesis
-
Zimniak P. Dubin-Johnson and Rotor syndromes: molecular basis and pathogenesis. Semin. Liver Dis. 13 (1993) 248-260
-
(1993)
Semin. Liver Dis.
, vol.13
, pp. 248-260
-
-
Zimniak, P.1
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