-
1
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole, S. P. C., G. Bhardwaj, J. H Gerlach, J. E. Mackie, C. E. Grant, K. C. Almquist, A. J. Stewart, E. U. Kurz, A. M. V. Duncan, and R. G. Deeley. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (Washington D. C.) 258:1650-1654 (1992).
-
(1992)
Science (Washington D. C.)
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.C.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
Stewart, A.J.7
Kurz, E.U.8
Duncan, A.M.V.9
Deeley, R.G.10
-
2
-
-
0028054888
-
Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs
-
Grant, C. E., G. Valdimarsson, D. R. Hipfner, K. C. Almquist, S. P. C. Cole, and R. G. Deeley. Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Res. 54:357-361 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 357-361
-
-
Grant, C.E.1
Valdimarsson, G.2
Hipfner, D.R.3
Almquist, K.C.4
Cole, S.P.C.5
Deeley, R.G.6
-
3
-
-
0029954845
-
Biology of the multidrug resistance-associated protein, MRP
-
Loe, D. W., R. G. Deeley, and S. P. C. Cole. Biology of the multidrug resistance-associated protein, MRP. Eur. J. Cancer 32A:945-957 (1996).
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 945-957
-
-
Loe, D.W.1
Deeley, R.G.2
Cole, S.P.C.3
-
4
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman, M. M., and I. Pastan. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62:385-427 (1993).
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
5
-
-
0024329881
-
The biochemistry of P-glycoprotein-mediated multidrug resistance
-
Endicott, J. A., and V. Ling. The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem. 58:137-171 (1989).
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 137-171
-
-
Endicott, J.A.1
Ling, V.2
-
6
-
-
0029821995
-
Multidrug resistance mediated by the multidrug resistance protein (MRP) gene
-
Lautier, D., Y. Canitrot, R. G. Deeley, and S. P. C. Cole. Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochem. Pharmacol. 52:967-977 (1996).
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 967-977
-
-
Lautier, D.1
Canitrot, Y.2
Deeley, R.G.3
Cole, S.P.C.4
-
7
-
-
0027960078
-
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells
-
Cole, S. P. C., K. E. Sparks, K. Fraser, D. W. Loe, C. E. Grant, G. M. Wilson, and R. G. Deeley. Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. Cancer Res. 54:5902-5910 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 5902-5910
-
-
Cole, S.P.C.1
Sparks, K.E.2
Fraser, K.3
Loe, D.W.4
Grant, C.E.5
Wilson, G.M.6
Deeley, R.G.7
-
8
-
-
0028961304
-
Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators
-
Tang-Wai, D. F., S. Kajiji, F. DiCapua, D. de Graaf, I. B. Roninson, and P. Gros. Human (MDR1) and mouse (mdr1, mdr3) P-glycoproteins can be distinguished by their respective drug resistance profiles and sensitivity to modulators. Biochemistry 34:32-39 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 32-39
-
-
Tang-Wai, D.F.1
Kajiji, S.2
DiCapua, F.3
De Graaf, D.4
Roninson, I.B.5
Gros, P.6
-
9
-
-
0028567035
-
The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump
-
Zaman, G. J. R., M. J. Flens, M. R van Leusden, M. de Haas, H. S. Mulder, J. Lankelma, H. M. Pinedo, R. J. Scheper, F. Baas, H. J. Broxterman, and P. Borst. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proc. Natl. Acad. Sci. USA 91:8822-8826 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8822-8826
-
-
Zaman, G.J.R.1
Flens, M.J.2
Van Leusden, M.R.3
De Haas, M.4
Mulder, H.S.5
Lankelma, J.6
Pinedo, H.M.7
Scheper, R.J.8
Baas, F.9
Broxterman, H.J.10
Borst, P.11
-
10
-
-
0028844581
-
Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution
-
Breuninger, L. M., S. Paul, K. Gaughan, T. Miki, A. Chan, S. A. Aaronson, and G. D. Kruh. Expression of multidrug resistance-associated protein in NIH/3T3 cells confers multidrug resistance associated with increased drug efflux and altered intracellular drug distribution. Cancer Res. 55:5342-5347 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 5342-5347
-
-
Breuninger, L.M.1
Paul, S.2
Gaughan, K.3
Miki, T.4
Chan, A.5
Aaronson, S.A.6
Kruh, G.D.7
-
11
-
-
0025267824
-
Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA
-
Lincke, C. R., A. M. van der Bliek, G. J. Schuurhuuis, T. van der Velde-Koerts, J. J. M. Smit, and P. Borst. Multidrug resistance phenotype of human BRO melanoma cells transfected with a wild-type human mdr1 complementary DNA. Cancer Res. 50:1779-1785 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 1779-1785
-
-
Lincke, C.R.1
Van Der Bliek, A.M.2
Schuurhuuis, G.J.3
Van Der Velde-Koerts, T.4
Smit, J.J.M.5
Borst, P.6
-
12
-
-
0026547001
-
Biochemical and genetic characterization of the multidrug resistance phenotype in murine macrophage-like J774.2 cells
-
Kirschner, L. S., L. M. Greenberger, S. I.-H. Hsu, C.-P. H. Yang, D. Cohen, R. L. Piekarz, G. Castillo, E. K.-H. Han, L. Yu, and S. B. Horwitz. Biochemical and genetic characterization of the multidrug resistance phenotype in murine macrophage-like J774.2 cells. Biochem. Pharmacol. 43: 77-87 (1992).
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 77-87
-
-
Kirschner, L.S.1
Greenberger, L.M.2
Hsu, S.I.-H.3
Yang, C.-P.H.4
Cohen, D.5
Piekarz, R.L.6
Castillo, G.7
Han, E.K.-H.8
Yu, L.9
Horwitz, S.B.10
-
13
-
-
0028956471
-
Using purified P-glycoprotein to understand multidrug resistance
-
Shapiro, A. B., and V. Ling. Using purified P-glycoprotein to understand multidrug resistance. J. Bioenerg. Biomem. 27:7-13 (1995).
-
(1995)
J. Bioenerg. Biomem.
, vol.27
, pp. 7-13
-
-
Shapiro, A.B.1
Ling, V.2
-
15
-
-
0029918142
-
ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein: Inhibition by cholestatic steroids
-
Loe, D. W., K. C. Almquist, S. P. C. Cole, and R. G. Deeley. ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein: inhibition by cholestatic steroids. J. Biol. Chem. 271:9683-9689 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9683-9689
-
-
Loe, D.W.1
Almquist, K.C.2
Cole, S.P.C.3
Deeley, R.G.4
-
16
-
-
0030009305
-
4 and chemotherapeutic agents in membrane vesicles: Demonstration of glutathione-dependent vincristine transport
-
4 and chemotherapeutic agents in membrane vesicles: demonstration of glutathione-dependent vincristine transport. J. Biol. Chem. 271:9675-9682 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9675-9682
-
-
Loe, D.W.1
Almquist, K.C.2
Deeley, R.G.3
Cole, S.P.C.4
-
17
-
-
0028578004
-
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport
-
Muller, M., C. Meijer, G. J. R. Zaman, P. Borst, R. J. Scheper, N. H. Mulder, E. G. E. de Vries, and P. L. M. Jansen. Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc. Natl. Acad. Sci. USA 91:13033-13037 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 13033-13037
-
-
Muller, M.1
Meijer, C.2
Zaman, G.J.R.3
Borst, P.4
Scheper, R.J.5
Mulder, N.H.6
De Vries, E.G.E.7
Jansen, P.L.M.8
-
18
-
-
0030063480
-
Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
-
Jedlitschky, G., I. Leier, U. Buchholz, K. Barnouin, G. Kurz, and D. Keppler. Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res. 56:988-994 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 988-994
-
-
Jedlitschky, G.1
Leier, I.2
Buchholz, U.3
Barnouin, K.4
Kurz, G.5
Keppler, D.6
-
19
-
-
0030009829
-
Cellular and in vitro transport of glutathione conjugates by MRP
-
Shen, H., S. Paul, L. M. Breuninger, P. J. Ciaccio, N. M. Laing, M. Helt, K. D. Tew, and G. D. Kruh. Cellular and in vitro transport of glutathione conjugates by MRP. Biochemistry 35:5719-5725 (1996).
-
(1996)
Biochemistry
, vol.35
, pp. 5719-5725
-
-
Shen, H.1
Paul, S.2
Breuninger, L.M.3
Ciaccio, P.J.4
Laing, N.M.5
Helt, M.6
Tew, K.D.7
Kruh, G.D.8
-
20
-
-
0024415437
-
Mechanisms of multidrug resistance in HL60 cells: Analysis of resistance associated membrane proteins and levels of mdr gene expression
-
McGrath, T., C. Latoud, S. T. Arnold, A. R. Safa, R. L. Felsted, and M. S. Center. Mechanisms of multidrug resistance in HL60 cells: analysis of resistance associated membrane proteins and levels of mdr gene expression. Biochem. Pharmacol. 38:3611-3619 (1989).
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 3611-3619
-
-
McGrath, T.1
Latoud, C.2
Arnold, S.T.3
Safa, A.R.4
Felsted, R.L.5
Center, M.S.6
-
21
-
-
0026068740
-
Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes
-
Buschman, E., and P. Gros. Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes. Mol. Cell. Biol. 11:595-603 (1991).
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 595-603
-
-
Buschman, E.1
Gros, P.2
-
22
-
-
0025253133
-
Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities
-
Devault, A., and P. Gros. Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities. Mol. Cell. Biol. 10:1652-1663 (1990).
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 1652-1663
-
-
Devault, A.1
Gros, P.2
-
23
-
-
0028229150
-
Disruption of the mouse mdrla P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel, A. H., J. J. M. Smit, O. van Tellingen, J. H. Beijnen, E. Wagenaar, L. van Deemter, C. A. A. M. Mol, M. A. van der Valk, E. C. Robanus-Manndag, H. P. J. te Riele, A. J. M. Berns, and P. Borst. Disruption of the mouse mdrla P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77:491-502 (1994).
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van Der Valk, M.A.8
Robanus-Manndag, E.C.9
Te Riele, H.P.J.10
Berns, A.J.M.11
Borst, P.12
-
24
-
-
0027969948
-
The human MDR3 P-glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice
-
Smith, A. J., J. L. P. M. Timmermans-Hereijgers, B. Roelofsen, K. W. A. Wirtz, W. J. van Blitterswijk, J. J. M. Smit, A. H. Schinkel, and P. Borst. The human MDR3 P-glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice. FEBS Lett. 354:263-266 (1994).
-
(1994)
FEBS Lett.
, vol.354
, pp. 263-266
-
-
Smith, A.J.1
Timmermans-Hereijgers, J.L.P.M.2
Roelofsen, B.3
Wirtz, K.W.A.4
Van Blitterswijk, W.J.5
Smit, J.J.M.6
Schinkel, A.H.7
Borst, P.8
-
25
-
-
0029939542
-
Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter
-
Stride, B. D., G. Valdimarsson, J. H. Gerlach, G. M. Wilson, S. P. C. Cole, and R. G. Deeley. Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter. Mol. Pharmacol. 49:962-971 (1996).
-
(1996)
Mol. Pharmacol.
, vol.49
, pp. 962-971
-
-
Stride, B.D.1
Valdimarsson, G.2
Gerlach, J.H.3
Wilson, G.M.4
Cole, S.P.C.5
Deeley, R.G.6
-
26
-
-
0028080927
-
Overexpression of the multidrug resistance-associated protein (MRP) gene in vincristine but not doxorubicin-selected multidrug-resistant murine erythroleukemia cells
-
Slapak, C. A., P. M. Fracasso, R. L. Martell, D. L. Toppmeyer, J.-M. Lecerf, and S. B. Levy. Overexpression of the multidrug resistance-associated protein (MRP) gene in vincristine but not doxorubicin-selected multidrug-resistant murine erythroleukemia cells. Cancer Res. 54:5607-5613 (1994).
-
(1994)
Cancer Res.
, vol.54
, pp. 5607-5613
-
-
Slapak, C.A.1
Fracasso, P.M.2
Martell, R.L.3
Toppmeyer, D.L.4
Lecerf, J.-M.5
Levy, S.B.6
-
27
-
-
0029028957
-
Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene
-
Lorico, A., R. G. Germino, S. Srimatkandada, C. V. Catapano, D. J. Fernandes, J. F. Germino, and A. C. Sartorelli. Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene. Cancer Res. 55:4352-4360 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 4352-4360
-
-
Lorico, A.1
Germino, R.G.2
Srimatkandada, S.3
Catapano, C.V.4
Fernandes, D.J.5
Germino, J.F.6
Sartorelli, A.C.7
-
28
-
-
0029076699
-
An episomal expression vector system for monitoring sequence-specific effects on mRNA stability in human cell lines
-
Wilson, G. M., and R. G. Deeley. An episomal expression vector system for monitoring sequence-specific effects on mRNA stability in human cell lines. Plasmid 33:198-207 (1995).
-
(1995)
Plasmid
, vol.33
, pp. 198-207
-
-
Wilson, G.M.1
Deeley, R.G.2
-
29
-
-
0028985382
-
Characterization of the 190 kDa multidrug resistance protein (MRP) in drug-selected and transfected human tumor cells
-
Almquist, K. C., D. W. Loe, D. R. Hipfner, J. E. Mackie, S. P. C. Cole, and R. G. Deeley. Characterization of the 190 kDa multidrug resistance protein (MRP) in drug-selected and transfected human tumor cells. Cancer Res. 55:102-110 (1995).
-
(1995)
Cancer Res.
, vol.55
, pp. 102-110
-
-
Almquist, K.C.1
Loe, D.W.2
Hipfner, D.R.3
Mackie, J.E.4
Cole, S.P.C.5
Deeley, R.G.6
-
30
-
-
0029987631
-
Location of a protease hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1
-
Hipfner, D. R., K. C. Almquist, B. D. Stride, R. G. Deeley, and S. P. C. Cole. Location of a protease hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1. Cancer Res. 56:3307-3314 (1996).
-
(1996)
Cancer Res.
, vol.56
, pp. 3307-3314
-
-
Hipfner, D.R.1
Almquist, K.C.2
Stride, B.D.3
Deeley, R.G.4
Cole, S.P.C.5
-
31
-
-
0025331434
-
Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell lines
-
Cole, S. P. C. Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell lines. Cancer Chemother. Pharmacol. 26:250-256 (1990).
-
(1990)
Cancer Chemother. Pharmacol.
, vol.26
, pp. 250-256
-
-
Cole, S.P.C.1
-
32
-
-
0025939987
-
Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: Evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II
-
Cole, S. P. C., E. R. Chanda, F. P. Dicke, J. H. Gerlach, and S. E. L. Mirski. Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II. Cancer Res. 51:3345-3352 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 3345-3352
-
-
Cole, S.P.C.1
Chanda, E.R.2
Dicke, F.P.3
Gerlach, J.H.4
Mirski, S.E.L.5
-
33
-
-
15844416284
-
Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells
-
Ishikawa, T., J. J. Bao, Y. Yamane, K. Akimaru, K. Frindrich, C. D. Wright, and M. T. Kuo. Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells. J. Biol. Chem. 271:14981-14988 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14981-14988
-
-
Ishikawa, T.1
Bao, J.J.2
Yamane, Y.3
Akimaru, K.4
Frindrich, K.5
Wright, C.D.6
Kuo, M.T.7
-
34
-
-
0008632564
-
Expression of a full-length cDNA for the human 'MDR1' gene confers resistance to colchicine, doxorubicin, and vinblastine
-
Ueda, K., C. Cardarelli, M. M. Gottesman, and I. Pastan. Expression of a full-length cDNA for the human 'MDR1' gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc. Natl. Acad. Sci. USA 84:3004-3008 (1987).
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 3004-3008
-
-
Ueda, K.1
Cardarelli, C.2
Gottesman, M.M.3
Pastan, I.4
-
35
-
-
0024292717
-
An altered pattern of cross-resistance in multidrug resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene
-
Choi, K., C.-J. Chen, M. Kriegler, and I. B. Roninson. An altered pattern of cross-resistance in multidrug resistant human cells results from spontaneous mutations in the mdr1 (P-glycoprotein) gene. Cell 53:519-529 (1988).
-
(1988)
Cell
, vol.53
, pp. 519-529
-
-
Choi, K.1
Chen, C.-J.2
Kriegler, M.3
Roninson, I.B.4
-
36
-
-
0027215242
-
Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site
-
Kajiji, S., F. Talbot, K. Grizzuti, V. Van Dyke-Phillips, M. Agresti, A. R. Safa, and P. Gros. Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site. Biochemistry 32:4185-4194 (1993).
-
(1993)
Biochemistry
, vol.32
, pp. 4185-4194
-
-
Kajiji, S.1
Talbot, F.2
Grizzuti, K.3
Van Dyke-Phillips, V.4
Agresti, M.5
Safa, A.R.6
Gros, P.7
-
37
-
-
0025766958
-
A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps
-
Gros, P., R. Dhir, J. Croop, and F. Talbot. A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps. Proc. Natl. Acad. Sci. USA 88:7289-7293 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7289-7293
-
-
Gros, P.1
Dhir, R.2
Croop, J.3
Talbot, F.4
|