-
1
-
-
0033926264
-
Quinolone generations: Natural history or natural selection
-
Ball P. 2000. Quinolone generations: Natural history or natural selection. J Antimicrob Chemother 46:17-24.
-
(2000)
J Antimicrob Chemother
, vol.46
, pp. 17-24
-
-
Ball, P.1
-
3
-
-
0035038683
-
Emerging mechanisms of fluoroquinolone resistance
-
Hooper DC. 2001. Emerging mechanisms of fluoroquinolone resistance. Emerg Infect Dis 7:337-341.
-
(2001)
Emerg Infect Dis
, vol.7
, pp. 337-341
-
-
Hooper, D.C.1
-
4
-
-
0037648419
-
Antibiotic efflux pumps in prokaryotic cells: Occurrence, impact on resistance and strategies for the future of antimicrobial therapy
-
Van Bambeke F, Glupczynski Y, Plésiat P, Pechère JC, Tulkens PM. 2003. Antibiotic efflux pumps in prokaryotic cells: Occurrence, impact on resistance and strategies for the future of antimicrobial therapy. J Antimicrob Chemother 51:1055-1065.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 1055-1065
-
-
Van Bambeke, F.1
Glupczynski, Y.2
Plésiat, P.3
Pechère, J.C.4
Tulkens, P.M.5
-
5
-
-
0038323939
-
Antibiotic efflux pumps in eukaryotic cells: Occurrence and impact on antibiotic cellular pharmacokinetics, pharmacodynamics and toxicodynamics
-
Van Bambeke F, Michot JM, Tulkens PM. 2003. Antibiotic efflux pumps in eukaryotic cells: Occurrence and impact on antibiotic cellular pharmacokinetics, pharmacodynamics and toxicodynamics. J Antimicrob Chemother 51:1067-1077.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 1067-1077
-
-
Van Bambeke, F.1
Michot, J.M.2
Tulkens, P.M.3
-
6
-
-
0033839497
-
The fluoroquinolone antibacterials: Past, present and future perspectives
-
Appelbaum PC, Hunter PA. 2000. The fluoroquinolone antibacterials: Past, present and future perspectives. Int J Antimicrob Agents 16:5-15.
-
(2000)
Int J Antimicrob Agents
, vol.16
, pp. 5-15
-
-
Appelbaum, P.C.1
Hunter, P.A.2
-
7
-
-
33745016515
-
Pharmacology of the fluoroquinolones: A perspective for the use in domestic animals
-
Martinez M, McDermott P, Walker R. 2006. Pharmacology of the fluoroquinolones: A perspective for the use in domestic animals. Vet J 172: 10-28.
-
(2006)
Vet J
, vol.172
, pp. 10-28
-
-
Martinez, M.1
McDermott, P.2
Walker, R.3
-
8
-
-
0001369472
-
Mechanism of action of nalidixic acid on Escherichia coli
-
Goss WA, Deitz WH, Cook TM. 1965. Mechanism of action of nalidixic acid on Escherichia coli. J Bacteriol 89:1068-1074.
-
(1965)
J Bacteriol
, vol.89
, pp. 1068-1074
-
-
Goss, W.A.1
Deitz, W.H.2
Cook, T.M.3
-
10
-
-
0028223448
-
Quinolone antibacterials. An update of their pharmacology and therapeutic use
-
Von Rosenstiel N, Adam D. 1994. Quinolone antibacterials. An update of their pharmacology and therapeutic use. Drugs 47:872-890.
-
(1994)
Drugs
, vol.47
, pp. 872-890
-
-
Von Rosenstiel, N.1
Adam, D.2
-
11
-
-
0035884910
-
Quinolone molecular structure-activity relationships: What we have learned about improving antimicrobial activity
-
Peterson LR. 2001. Quinolone molecular structure-activity relationships: What we have learned about improving antimicrobial activity. Clin Infect Dis 33: S180-S186.
-
(2001)
Clin Infect Dis
, vol.33
-
-
Peterson, L.R.1
-
12
-
-
0023145820
-
Monocyclic and tricyclic analogs of quinolones: Mechanism of action
-
Georgopapadakou N, Dix B, Angehrn P, Wick A, Olson G. 1987. Monocyclic and tricyclic analogs of quinolones: Mechanism of action. J Antimicrob Chemother 31:614-616.
-
(1987)
J Antimicrob Chemother
, vol.31
, pp. 614-616
-
-
Georgopapadakou, N.1
Dix, B.2
Angehrn, P.3
Wick, A.4
Olson, G.5
-
13
-
-
0026468457
-
The molecular basis of quinolone action
-
Maxwell A. 1992. The molecular basis of quinolone action. J Antimicrob Chemother 30:409-414.
-
(1992)
J Antimicrob Chemother
, vol.30
, pp. 409-414
-
-
Maxwell, A.1
-
14
-
-
0028034698
-
The complex of DNA gyrase and quinolone drugs with DNA forms a barrier to transcription by RNA polymerase
-
Willmott CJ, Critchlow SE, Eperon IC, Maxwell A. 1994. The complex of DNA gyrase and quinolone drugs with DNA forms a barrier to transcription by RNA polymerase. J Mol Biol 242:351-363.
-
(1994)
J Mol Biol
, vol.242
, pp. 351-363
-
-
Willmott, C.J.1
Critchlow, S.E.2
Eperon, I.C.3
Maxwell, A.4
-
15
-
-
0031407768
-
DNA gyrase, topoisomerase IV, and the 4-quinolones
-
Drlica K, Zhao X. 1997. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol 61:377-392.
-
(1997)
Microbiol Mol Biol
, vol.61
, pp. 377-392
-
-
Drlica, K.1
Zhao, X.2
-
16
-
-
0028174984
-
DNA topoisomerases: Essential enzymes and lethal targets
-
Chen AY, Liu LF. 1994. DNA topoisomerases: Essential enzymes and lethal targets. Annu Rev Pharmacol Toxicol 34:191-218.
-
(1994)
Annu Rev Pharmacol Toxicol
, vol.34
, pp. 191-218
-
-
Chen, A.Y.1
Liu, L.F.2
-
17
-
-
1542603083
-
Fluoroquinolones: Mechanism of action, classification, and development of resistance
-
Blondeau JM. 2004. Fluoroquinolones: Mechanism of action, classification, and development of resistance. Surv Ophthalmol 49:S73-S78.
-
(2004)
Surv Ophthalmol
, vol.49
-
-
Blondeau, J.M.1
-
19
-
-
0024516261
-
Pharmacokinetic disposition of quinolones in human body fluids and tissues
-
Sörgel F, Jaehde U, Naber KG, Stephan U. 1989. Pharmacokinetic disposition of quinolones in human body fluids and tissues. Clin Pharmacokinet 16:51S-68S.
-
(1989)
Clin Pharmacokinet
, vol.16
-
-
Sörgel, F.1
Jaehde, U.2
Naber, K.G.3
Stephan, U.4
-
21
-
-
0041716722
-
Intestinal elimination of ofloxacin enantiomers in the rat: Evidence of a carrier-mediated process
-
Rabbaa L, Dautrey S, Colas-Linhart N, Carbon C, Farinotti R. 1996. Intestinal elimination of ofloxacin enantiomers in the rat: Evidence of a carrier-mediated process. Antimicrob Agents Chemother 36:2506-2511.
-
(1996)
Antimicrob Agents Chemother
, vol.36
, pp. 2506-2511
-
-
Rabbaa, L.1
Dautrey, S.2
Colas-Linhart, N.3
Carbon, C.4
Farinotti, R.5
-
22
-
-
0026599145
-
J774 macrophages secrete antibiotics via organic anion transporters
-
Cao CX, Silverstein SC, Neu C, Steinberg TH. 1992. J774 macrophages secrete antibiotics via organic anion transporters. J Infect Dis 165:322-328.
-
(1992)
J Infect Dis
, vol.165
, pp. 322-328
-
-
Cao, C.X.1
Silverstein, S.C.2
Neu, C.3
Steinberg, T.H.4
-
23
-
-
0027411562
-
Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco-2 cell layers
-
Griffiths NM, Hirst BH, Simmons NL. 1993. Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco-2 cell layers. Br J Pharmacol 108:575-576.
-
(1993)
Br J Pharmacol
, vol.108
, pp. 575-576
-
-
Griffiths, N.M.1
Hirst, B.H.2
Simmons, N.L.3
-
24
-
-
0028321687
-
Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and Pefloxacin; a common secretory pathway
-
Griffiths NM, Hirst BH, Simmons NL. 1994. Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and Pefloxacin; a common secretory pathway. J Pharmacol Exp Ther 269:496-502.
-
(1994)
J Pharmacol Exp Ther
, vol.269
, pp. 496-502
-
-
Griffiths, N.M.1
Hirst, B.H.2
Simmons, N.L.3
-
25
-
-
0035685449
-
Complete characterization of the human ABC gene family
-
Dean M, Allikmets R. 2001. Complete characterization of the human ABC gene family. J Bioenerg Biomembr 33:475-479.
-
(2001)
J Bioenerg Biomembr
, vol.33
, pp. 475-479
-
-
Dean, M.1
Allikmets, R.2
-
26
-
-
0037457802
-
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview
-
Schinkel AH, Jonker JW. 2003. Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: An overview. Adv Drug Deliver Rev 55:3-29.
-
(2003)
Adv Drug Deliver Rev
, vol.55
, pp. 3-29
-
-
Schinkel, A.H.1
Jonker, J.W.2
-
27
-
-
0036792874
-
Multidrug resistance and cancer: The role of the human ABC transporter AB CG2
-
Ejendal KFK, Hrycyna CA. 2002. Multidrug resistance and cancer: The role of the human ABC transporter AB CG2. Curr Protein Pept Sci 3: 503-511.
-
(2002)
Curr Protein Pept Sci
, vol.3
, pp. 503-511
-
-
Ejendal, K.F.K.1
Hrycyna, C.A.2
-
28
-
-
0042167430
-
P-Glycoprotein inhibitors and their screening: A perspective from bioavailability enhancement
-
Varma MVS, Ashokraj Y, Dey CS, Pachagnula R. 2003. P-Glycoprotein inhibitors and their screening: A perspective from bioavailability enhancement. Pharmacol Res 48:347-359.
-
(2003)
Pharmacol Res
, vol.48
, pp. 347-359
-
-
Varma, M.V.S.1
Ashokraj, Y.2
Dey, C.S.3
Pachagnula, R.4
-
29
-
-
2542491777
-
The role of ABC transporters in drug resistance, metabolism and toxicity
-
Glavinas H, Krajcsi P, Cserepes J, Sarkadi B. 2004. The role of ABC transporters in drug resistance, metabolism and toxicity. Curr Drug Deliv 1: 27-42.
-
(2004)
Curr Drug Deliv
, vol.1
, pp. 27-42
-
-
Glavinas, H.1
Krajcsi, P.2
Cserepes, J.3
Sarkadi, B.4
-
30
-
-
17544368685
-
Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
-
Leslie EM, Deeley RG, Cole SP. 2005. Multidrug resistance proteins: Role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol 204:216-237.
-
(2005)
Toxicol Appl Pharmacol
, vol.204
, pp. 216-237
-
-
Leslie, E.M.1
Deeley, R.G.2
Cole, S.P.3
-
31
-
-
33644847684
-
Transporters as a determinant of drug clearance and tissue distribution
-
Shitara Y, Horie T, Sugiyama Y. 2006. Transporters as a determinant of drug clearance and tissue distribution. Eur J Pharm Sci 27:425-446.
-
(2006)
Eur J Pharm Sci
, vol.27
, pp. 425-446
-
-
Shitara, Y.1
Horie, T.2
Sugiyama, Y.3
-
32
-
-
0031692747
-
Secretion of Sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors
-
Cormet-Boyaka E, Huneau JF, Mordrelle A, Boyaka PN, Carbon C, Rubinstein E, Tome D. 1998. Secretion of Sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors. Antimicrob Agents Chemother 42:2607-2611.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2607-2611
-
-
Cormet-Boyaka, E.1
Huneau, J.F.2
Mordrelle, A.3
Boyaka, P.N.4
Carbon, C.5
Rubinstein, E.6
Tome, D.7
-
33
-
-
0032464623
-
Transport of quinolone antibacterial drugs in a kidney epithelial cell line, LLC- PK1
-
Matsuo Y, Yano I, Ito T, Hashimoto Y, Inui K. 1998. Transport of quinolone antibacterial drugs in a kidney epithelial cell line, LLC- PK1. J Pharmacol Exp Ther 287:672-678.
-
(1998)
J Pharmacol Exp Ther
, vol.287
, pp. 672-678
-
-
Matsuo, Y.1
Yano, I.2
Ito, T.3
Hashimoto, Y.4
Inui, K.5
-
34
-
-
33645108568
-
Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion
-
Merino G, Alvarez AI, Pulido MM, Molina AJ, Schinkel AH, Prieto JG. 2006. Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion. Drug Metab Dispos 34:690-695.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 690-695
-
-
Merino, G.1
Alvarez, A.I.2
Pulido, M.M.3
Molina, A.J.4
Schinkel, A.H.5
Prieto, J.G.6
-
35
-
-
0036175308
-
Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo
-
Yamaguchi H, Yano I, Saito H, Inui KI. 2002. Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo. J Pharmacol Exp Ther 300:1063-1069.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 1063-1069
-
-
Yamaguchi, H.1
Yano, I.2
Saito, H.3
Inui, K.I.4
-
36
-
-
16644374851
-
Cotransport of macrolide and fluoroquinolones, a beneficial interaction reversing P-glycoprotein efflux
-
Sikri V, Pal D, Jain R, Kalyani D, Mitra AK. 2004. Cotransport of macrolide and fluoroquinolones, a beneficial interaction reversing P-glycoprotein efflux. Am J Ther 11:433-442.
-
(2004)
Am J Ther
, vol.11
, pp. 433-442
-
-
Sikri, V.1
Pal, D.2
Jain, R.3
Kalyani, D.4
Mitra, A.K.5
-
37
-
-
0032793835
-
Stereoselective permeation of new fluorinated quinolone derivatives across LLC-PK1 cell monolayers
-
Sasaya M, Hatakeyama Y, Saitoh H, Takada M. 1999. Stereoselective permeation of new fluorinated quinolone derivatives across LLC-PK1 cell monolayers. Biol Pharm Bull 22:707-712.
-
(1999)
Biol Pharm Bull
, vol.22
, pp. 707-712
-
-
Sasaya, M.1
Hatakeyama, Y.2
Saitoh, H.3
Takada, M.4
-
38
-
-
0037421590
-
Pharmacogenomics and drug disposition, drug targets, and side effects
-
Evans WE, McLeod HL. 2003. Pharmacogenomics and drug disposition, drug targets, and side effects. N Engl J Med 348:538-549.
-
(2003)
N Engl J Med
, vol.348
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
39
-
-
10044257623
-
Recent advances in pharmacogenetic approaches to anticancer drug development
-
Smith N, Figg WD, Sparreboom A. 2004. Recent advances in pharmacogenetic approaches to anticancer drug development. Drug Dev Res 62:233-253.
-
(2004)
Drug Dev Res
, vol.62
, pp. 233-253
-
-
Smith, N.1
Figg, W.D.2
Sparreboom, A.3
-
40
-
-
30144435485
-
The genetics of ATP-binding cassette transporters
-
Dean M. 2005. The genetics of ATP-binding cassette transporters. Methods Enzymol 400:409-429.
-
(2005)
Methods Enzymol
, vol.400
, pp. 409-429
-
-
Dean, M.1
-
41
-
-
0036724716
-
Fluoroquinolone resistance among Grampositive cocci
-
Hooper DC. 2002. Fluoroquinolone resistance among Grampositive cocci. Lancet Infect Dis 2: 530-538.
-
(2002)
Lancet Infect Dis
, vol.2
, pp. 530-538
-
-
Hooper, D.C.1
-
43
-
-
1242314678
-
Effect of cisplatin-induced acute renal failure on bioavailability and intestinal secretion of quinolone antibacterial drugs in rat
-
Yamaguchi H, Yano I, Saito H, Inui KI. 2004. Effect of cisplatin-induced acute renal failure on bioavailability and intestinal secretion of quinolone antibacterial drugs in rat. Pharm Res 21:330-338.
-
(2004)
Pharm Res
, vol.21
, pp. 330-338
-
-
Yamaguchi, H.1
Yano, I.2
Saito, H.3
Inui, K.I.4
-
44
-
-
0036178134
-
A critical review of the fluoroquinolones: Focus on respiratory infections
-
Zhanel GG, Ennis K, Vercaigne L, Walkty A, Gin AS, Embil J, Smith H, Hoban DJ. 2002. A critical review of the fluoroquinolones: Focus on respiratory infections. Drugs 62:13-59.
-
(2002)
Drugs
, vol.62
, pp. 13-59
-
-
Zhanel, G.G.1
Ennis, K.2
Vercaigne, L.3
Walkty, A.4
Gin, A.S.5
Embil, J.6
Smith, H.7
Hoban, D.J.8
-
45
-
-
33847165756
-
Danoflox-acin-mesylate is a substrate for ATP-dependent efflux transporters
-
Schrickx JA, Fink-Gremmels J. 2007. Danoflox-acin-mesylate is a substrate for ATP-dependent efflux transporters. Br J Pharmacol 150:463-469.
-
(2007)
Br J Pharmacol
, vol.150
, pp. 463-469
-
-
Schrickx, J.A.1
Fink-Gremmels, J.2
-
46
-
-
33745726825
-
Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): Influence of flavonoids and role in milk secretion in sheep
-
Pulido MM, Molina AJ, Merino G, Mendoza G, Prieto JG, Alvarez AI. 2006. Interaction of enrofloxacin with breast cancer resistance protein (BCRP/ABCG2): Influence of flavonoids and role in milk secretion in sheep. J Vet Pharmacol Ther 29:279-287.
-
(2006)
J Vet Pharmacol Ther
, vol.29
, pp. 279-287
-
-
Pulido, M.M.1
Molina, A.J.2
Merino, G.3
Mendoza, G.4
Prieto, J.G.5
Alvarez, A.I.6
-
47
-
-
0030807188
-
Fluoroquinolone (ciprofloxacin) secretion by human intestinal epithelial (Caco-2) cells
-
Cavet ME, West M, Simmons NL. 1997. Fluoroquinolone (ciprofloxacin) secretion by human intestinal epithelial (Caco-2) cells. Br J Pharmacol 121:1567-1578.
-
(1997)
Br J Pharmacol
, vol.121
, pp. 1567-1578
-
-
Cavet, M.E.1
West, M.2
Simmons, N.L.3
-
48
-
-
0032775326
-
Active intestinal elimination of ciprofloxacin in rats: Modulation by different substrates
-
Dautrey S, Felice K, Petiet A, Lacour B, Carbon C, Farinotti R. 1999. Active intestinal elimination of ciprofloxacin in rats: Modulation by different substrates. Br J Pharmacol 127:1728-1734.
-
(1999)
Br J Pharmacol
, vol.127
, pp. 1728-1734
-
-
Dautrey, S.1
Felice, K.2
Petiet, A.3
Lacour, B.4
Carbon, C.5
Farinotti, R.6
-
49
-
-
0036199337
-
Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells
-
Lowes S, Simmons NL. 2002. Multiple pathways for fluoroquinolone secretion by human intestinal epithelial (Caco-2) cells. Br J Pharmacol 135:1263-1275.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 1263-1275
-
-
Lowes, S.1
Simmons, N.L.2
-
50
-
-
0033798408
-
Secretory mechanisms of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2
-
Yamaguchi H, Yano I, Hashimoto Y, Inui KI. 2000. Secretory mechanisms of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2. J Pharmacol Exp Ther 295:360-366.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 360-366
-
-
Yamaguchi, H.1
Yano, I.2
Hashimoto, Y.3
Inui, K.I.4
-
51
-
-
0035941155
-
Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2
-
Yamaguchi H, Yano I, Saito H, Inui KI. 2001. Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2. Eur J Pharmacol 431:297-303.
-
(2001)
Eur J Pharmacol
, vol.431
, pp. 297-303
-
-
Yamaguchi, H.1
Yano, I.2
Saito, H.3
Inui, K.I.4
-
52
-
-
0036146666
-
Involvement of multidrug resistance-associated protein 2 in intestinal secretion of grepafloxacin in rats
-
Naruhashi K, Tamai I, Inoue N, Muraoka H, Sai Y, Suzuki N, Tsuji A. 2002. Involvement of multidrug resistance-associated protein 2 in intestinal secretion of grepafloxacin in rats. Antimicrob Agents Chemother 46:344-349.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 344-349
-
-
Naruhashi, K.1
Tamai, I.2
Inoue, N.3
Muraoka, H.4
Sai, Y.5
Suzuki, N.6
Tsuji, A.7
-
53
-
-
17844383698
-
Expression, localization, and functional characteristics of breast cancer resistance protein in Caco-2 cells
-
Xia CQ, Liu N, Yang D, Miwa G, Gan LS. 2005. Expression, localization, and functional characteristics of breast cancer resistance protein in Caco-2 cells. Drug Metab Dispos 33:637-643.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 637-643
-
-
Xia, C.Q.1
Liu, N.2
Yang, D.3
Miwa, G.4
Gan, L.S.5
-
54
-
-
18744366654
-
Kinetic modelling of the intestinal transport of sarafloxacin. Studies in situ in rat and in vitro in Caco-2 cells
-
Fernandez-Teruel C, Gonzalez-Alvarez I, Casabo VG, Ruiz-Garcia A, Bermejo M. 2005. Kinetic modelling of the intestinal transport of sarafloxacin. Studies in situ in rat and in vitro in Caco-2 cells. J Drug Target 13:199-212.
-
(2005)
J Drug Target
, vol.13
, pp. 199-212
-
-
Fernandez-Teruel, C.1
Gonzalez-Alvarez, I.2
Casabo, V.G.3
Ruiz-Garcia, A.4
Bermejo, M.5
-
56
-
-
0031911625
-
Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats
-
Sasabe H, Tsuji A, Sugiyama Y. 1998. Carrier-mediated mechanism for the biliary excretion of the quinolone antibiotic grepafloxacin and its glucuronide in rats. J Pharmacol Exp Ther 284:1033-1039.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 1033-1039
-
-
Sasabe, H.1
Tsuji, A.2
Sugiyama, Y.3
-
57
-
-
0031884441
-
Stereoselective hepatobiliary transport of the quinolone antibiotic grepafloxacin and its glucuronide in the rat
-
Sasabe H, Kato Y, Tsuji A, Sugiyama Y. 1998. Stereoselective hepatobiliary transport of the quinolone antibiotic grepafloxacin and its glucuronide in the rat. J Pharmacol Exp Ther 284:661-668.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 661-668
-
-
Sasabe, H.1
Kato, Y.2
Tsuji, A.3
Sugiyama, Y.4
-
58
-
-
0036126408
-
Possible involvement of P-glycoprotein in the biliary excretion of grepafloxaein
-
Zhao YL, Cai SH, Wang L, Kitaichi K, Tatsumi Y, Nadai M, Yoshizumi H, Takagi K, Takagi K, Hasegawa T. 2002. Possible involvement of P-glycoprotein in the biliary excretion of grepafloxaein. Clin Exp Pharmacol Physiol 29:167-172.
-
(2002)
Clin Exp Pharmacol Physiol
, vol.29
, pp. 167-172
-
-
Zhao, Y.L.1
Cai, S.H.2
Wang, L.3
Kitaichi, K.4
Tatsumi, Y.5
Nadai, M.6
Yoshizumi, H.7
Takagi, K.8
Takagi, K.9
Hasegawa, T.10
-
59
-
-
3342900005
-
Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxaein in mice
-
Sasabe H, Kato Y, Suzuki T, Itose M, Miyamoto G, Sugiyama Y. 2004. Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxaein in mice. J Pharmacol Exp Ther 310:648-655.
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 648-655
-
-
Sasabe, H.1
Kato, Y.2
Suzuki, T.3
Itose, M.4
Miyamoto, G.5
Sugiyama, Y.6
-
60
-
-
0034093175
-
Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells
-
Terashi K, Oka M, Soda H, Fukuda M, Kawabata S, Nakatomi K, Shiozawa K, Nakamura T, Tsukamoto K, Noguchi Y, Suenaga M, Tei C, Kohno S. 2000. Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells. Antimicrob Agents Chemother 44:1697-1700.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1697-1700
-
-
Terashi, K.1
Oka, M.2
Soda, H.3
Fukuda, M.4
Kawabata, S.5
Nakatomi, K.6
Shiozawa, K.7
Nakamura, T.8
Tsukamoto, K.9
Noguchi, Y.10
Suenaga, M.11
Tei, C.12
Kohno, S.13
-
61
-
-
34748877360
-
Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones
-
Ando T, Kusuhara H, Merino G, Alvarez AI, Schinkel AH, Sugiyama Y. 2007. Involvement of breast cancer resistance protein (ABCG2) in the biliary excretion mechanism of fluoroquinolones. Drug Metab Dispos 35:1873-1879.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 1873-1879
-
-
Ando, T.1
Kusuhara, H.2
Merino, G.3
Alvarez, A.I.4
Schinkel, A.H.5
Sugiyama, Y.6
-
62
-
-
0031941928
-
Effects of probenecid and Cimetidine on renal disposition of ofloxacin in rats
-
Foote EF, Halstenson CE. 1998. Effects of probenecid and Cimetidine on renal disposition of ofloxacin in rats. Antimicrob Agents Chemother 42:456-458.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 456-458
-
-
Foote, E.F.1
Halstenson, C.E.2
-
63
-
-
0032901503
-
Distribution characteristics of levofloxacin and grepafloxaein in rat kidney
-
Ito T, Yano I, Masuda S, Hashimoto Y, Inui K. 1999. Distribution characteristics of levofloxacin and grepafloxaein in rat kidney. Pharm Res 16: 534-539.
-
(1999)
Pharm Res
, vol.16
, pp. 534-539
-
-
Ito, T.1
Yano, I.2
Masuda, S.3
Hashimoto, Y.4
Inui, K.5
-
64
-
-
0034017506
-
Transepithelial transport of levofloxacin in the isolated perfused rat kidney
-
Ito T, Yano I, Hashimoto Y, Inui K. 2000. Transepithelial transport of levofloxacin in the isolated perfused rat kidney. Pharm Res 17:236-241.
-
(2000)
Pharm Res
, vol.17
, pp. 236-241
-
-
Ito, T.1
Yano, I.2
Hashimoto, Y.3
Inui, K.4
-
65
-
-
8544227674
-
-
Ito T,Yano I.Tanaka K,Inui K. 1997. Transport of quinolone antibacterial drugs by human P-Glycoprotein expressed in a kidney epithelial cell line, LLC-PK1. J Pharmacol Exp Ther 282:955-960.
-
Ito T,Yano I.Tanaka K,Inui K. 1997. Transport of quinolone antibacterial drugs by human P-Glycoprotein expressed in a kidney epithelial cell line, LLC-PK1. J Pharmacol Exp Ther 282:955-960.
-
-
-
-
66
-
-
0030826493
-
The transport of ciprofloxacin in cultured kidney epithelial cells LLC-PK1
-
Sasaya M, Oda M, Endo T, Saitoh H, Takada M. 1997. The transport of ciprofloxacin in cultured kidney epithelial cells LLC-PK1. Biol Pharm Bull 20:887-891.
-
(1997)
Biol Pharm Bull
, vol.20
, pp. 887-891
-
-
Sasaya, M.1
Oda, M.2
Endo, T.3
Saitoh, H.4
Takada, M.5
-
67
-
-
0033815392
-
Limited distribution of new quinolone antibacterial agents into brain caused by multiple efflux transporters at the blood-brain barrier
-
Tamai I, Yamashita J, Kido Y, Ohnari A, Sai Y, Shima Y, Naruhashi K, Koizumi S, Tsuji A. 2000. Limited distribution of new quinolone antibacterial agents into brain caused by multiple efflux transporters at the blood-brain barrier. J Pharmacol Exp Ther 295:146-152.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 146-152
-
-
Tamai, I.1
Yamashita, J.2
Kido, Y.3
Ohnari, A.4
Sai, Y.5
Shima, Y.6
Naruhashi, K.7
Koizumi, S.8
Tsuji, A.9
-
68
-
-
0030610838
-
Quantitative brain microdialysis study on the mechanism of quinolones distribution in the central nervous system
-
Ooie T, Suzuki H, Terasaki T, Sugiyama Y. 1997. Quantitative brain microdialysis study on the mechanism of quinolones distribution in the central nervous system. Drug Metab Disp 25:784-789.
-
(1997)
Drug Metab Disp
, vol.25
, pp. 784-789
-
-
Ooie, T.1
Suzuki, H.2
Terasaki, T.3
Sugiyama, Y.4
-
69
-
-
0030799004
-
Kinetic evidence for active efflux transport across the blood-brain barrier of quinolone antibiotics
-
Ooie T, Suzuki H, Terasaki T, Sugiyama Y. 1997. Kinetic evidence for active efflux transport across the blood-brain barrier of quinolone antibiotics. J Pharmacol Exp Ther 283:293-304.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 293-304
-
-
Ooie, T.1
Suzuki, H.2
Terasaki, T.3
Sugiyama, Y.4
-
70
-
-
0031691115
-
A new approach for early assessment of the epileptogenic potential of quinolones
-
Delon A, Pariat C, Courtois P, Bouquet S, Couet W. 1998. A new approach for early assessment of the epileptogenic potential of quinolones. Antimicrob Agents Chemother 42:2756-27585.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 2756-27585
-
-
Delon, A.1
Pariat, C.2
Courtois, P.3
Bouquet, S.4
Couet, W.5
-
71
-
-
0033743228
-
In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of Sparfloxacin
-
Lange EC, Marchand S, van den Berg D, van der Sandt IC, de Boer AG, Delon A, Bouquet S, Couet W. 2000. In vitro and in vivo investigations on fluoroquinolones; effects of the P-glycoprotein efflux transporter on brain distribution of Sparfloxacin. Eur J Pharm Sci 12:85-93.
-
(2000)
Eur J Pharm Sci
, vol.12
, pp. 85-93
-
-
Lange, E.C.1
Marchand, S.2
van den Berg, D.3
van der Sandt, I.C.4
de Boer, A.G.5
Delon, A.6
Bouquet, S.7
Couet, W.8
-
72
-
-
2342644918
-
Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier
-
Cisternino S, Mercier C, Bourasset F, Roux F, Scherrmann JM. 2004. Expression, up-regulation, and transport activity of the multidrug-resistance protein Abcg2 at the mouse blood-brain barrier. Cancer Res 64:3296-3301.
-
(2004)
Cancer Res
, vol.64
, pp. 3296-3301
-
-
Cisternino, S.1
Mercier, C.2
Bourasset, F.3
Roux, F.4
Scherrmann, J.M.5
-
73
-
-
14644409841
-
The breast cancer resistance protein BCRP (ABCG2) concentrates drug and carcinogenic xenotoxins into milk
-
Jonker JW, Merino G, Musters S, Van Herwaarden AE, Bolscher E, Wagenaar E, Mesman E, Dale TC, Schinkel AH. 2005. The breast cancer resistance protein BCRP (ABCG2) concentrates drug and carcinogenic xenotoxins into milk. Nat Med 11: 127-129.
-
(2005)
Nat Med
, vol.11
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
Van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
Mesman, E.7
Dale, T.C.8
Schinkel, A.H.9
-
74
-
-
33644855549
-
Carrier-mediated uptake of grepafloxaein, a fluoroquinolone antibiotic, by the isolated rat lung cells
-
Sasabe H, Kato Y, Suzuki T, Itose M, Miyamoto G, Sugiyama Y. 2005. Carrier-mediated uptake of grepafloxaein, a fluoroquinolone antibiotic, by the isolated rat lung cells. Drug Metab Pharmacokinet 20:491-495.
-
(2005)
Drug Metab Pharmacokinet
, vol.20
, pp. 491-495
-
-
Sasabe, H.1
Kato, Y.2
Suzuki, T.3
Itose, M.4
Miyamoto, G.5
Sugiyama, Y.6
-
75
-
-
33846877217
-
Functional studies on the activity of efflux transporters in an ex vivo model with chicken splenocytes and evaluation of selected fluoroquinolones in this model
-
Haritova AM, Schrickx JA, Fink-Gremmels J. 2007. Functional studies on the activity of efflux transporters in an ex vivo model with chicken splenocytes and evaluation of selected fluoroquinolones in this model. Biochem Pharmacol 73:752-759.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 752-759
-
-
Haritova, A.M.1
Schrickx, J.A.2
Fink-Gremmels, J.3
-
76
-
-
0038101671
-
Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus
-
Seral C, Carryn S, Tulkens PM, Van Bambeke F. 2003. Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus. J Antimicrob Chemother 51:1167-1173.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 1167-1173
-
-
Seral, C.1
Carryn, S.2
Tulkens, P.M.3
Van Bambeke, F.4
-
77
-
-
19544390531
-
Related articles, influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages
-
Michot JM, Seral C, Van Bambeke F, Mingeot-Leclercq MP, Tulkens PM. 2005. Related articles, influence of efflux transporters on the accumulation and efflux of four quinolones (ciprofloxacin, levofloxacin, garenoxacin, and moxifloxacin) in J774 macrophages. Antimicrob Agents Chemother 49: 2429-2437.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 2429-2437
-
-
Michot, J.M.1
Seral, C.2
Van Bambeke, F.3
Mingeot-Leclercq, M.P.4
Tulkens, P.M.5
-
78
-
-
33646448262
-
Cellular accumulation and activity of quinolones in ciprofloxacin-resistant J774 macrophages
-
Michot JM, Heremans MF, Caceres NE, Mingeot-Leclercq MP, Tulkens PM, Van Bambeke F. 2006. Cellular accumulation and activity of quinolones in ciprofloxacin-resistant J774 macrophages. Antimicrob Agents Chemother 50:1689-1695.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1689-1695
-
-
Michot, J.M.1
Heremans, M.F.2
Caceres, N.E.3
Mingeot-Leclercq, M.P.4
Tulkens, P.M.5
Van Bambeke, F.6
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