Role of tumor necrosis factor-α in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin

European Journal of Pharmacology

Volumn 507, Issue 1-3, 2005, Pages 229-237

  Miyoshi, Mika ^a   Nadai, Masayuki ^b   Nitta, Atsumi ^c   Ueyama, Jun ^a   Shimizu, Akemi ^a   Takagi, Kenji ^a   Nabeshima, Toshitaka ^c   Takagi, Kenzo ^a   Saito, Kuniaki ^d   Hasegawa, Takaaki ^e  

^a NAGOYA UNIVERSITY   (Japan)

^b MEIJO UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cytochrome P450 (CYP); Endotoxin; P glycoprotein; TNF knockout mice; Tumor necrosis factor (TNF )

Indexed keywords

CYTOCHROME P450 2C11; CYTOCHROME P450 3A2; CYTOCHROME P450 ISOENZYME; CYTOKINE; DOXORUBICIN; GLYCOPROTEIN P; PHENAZONE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG BLOOD LEVEL; LIVER MICROSOME METABOLISM; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; SPECIES COMPARISON; WILD TYPE;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DOWN-REGULATION; ENDOTOXINS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; P-GLYCOPROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 19944431266     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.11.035     Document Type: Article

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