Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats

European Journal of Pharmacology

Volumn 501, Issue 1-3, 2004, Pages 151-159

  Shimizu, Akemi ^a   Miyoshi, Mika ^a   Sugie, Masami ^a   Ueyama, Jun ^a   Yamaguchi, Takuji ^b,c   Sasaki, Toshinobu ^b,c   Takagi, Kenzo ^a   Jin, Mingji ^d   Miyamoto, Ken Ichi ^b,d   Tsuji, Akira ^b   Hasegawa, Takaaki ^a,e  

^a NAGOYA UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c TSUMURA AND CO   (Japan)

^d KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

^e AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

(Rat); Multidrug resistance associated protein 2 (Mrp2); P glycoprotein; Pazufloxacin; Quinolone antimicrobial agent; Renal excretion

Indexed keywords

CYCLOSPORIN; DOXORUBICIN; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 2; PAZUFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN;

ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG ELIMINATION; DRUG EXCRETION; GENE OVEREXPRESSION; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN CELL; KIDNEY; KIDNEY CLEARANCE; LEUKEMIA CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; URINARY EXCRETION;

ANIMALS; CELL LINE, TUMOR; FLUOROQUINOLONES; KIDNEY; MALE; OXAZINES; P-GLYCOPROTEIN; RATS; RATS, MUTANT STRAINS; RATS, SPRAGUE-DAWLEY;

EID: 4644353268     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.08.013     Document Type: Article

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