-
2
-
-
0037223174
-
Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
-
A.H. Mokdad E.S. Ford B.A. Bowman W.H. Dietz F. Vinicor V.S. Bales Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001 Jama 289 2003 76 79
-
(2003)
Jama
, vol.289
, pp. 76-79
-
-
Mokdad, A.H.1
Ford, E.S.2
Bowman, B.A.3
Dietz, W.H.4
Vinicor, F.5
Bales, V.S.6
-
4
-
-
8144220518
-
Prevention Conference VII: Obesity, a worldwide epidemic related to heart disease and stroke: executive summary
-
R.H. Eckel D.A. York S. Rossner V. Hubbard I. Caterson S.T. St Jeor Prevention Conference VII: Obesity, a worldwide epidemic related to heart disease and stroke: executive summary Circulation 110 2004 2968 2975
-
(2004)
Circulation
, vol.110
, pp. 2968-2975
-
-
Eckel, R.H.1
York, D.A.2
Rossner, S.3
Hubbard, V.4
Caterson, I.5
St Jeor, S.T.6
-
5
-
-
8144231115
-
Clinical implications of obesity with specific focus on cardiovascular disease: a statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism: endorsed by the American College of Cardiology Foundation
-
S. Klein L.E. Burke G.A. Bray S. Blair D.B. Allison X. Pi-Sunyer Clinical implications of obesity with specific focus on cardiovascular disease: a statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism: endorsed by the American College of Cardiology Foundation Circulation 110 2004 2952 2967
-
(2004)
Circulation
, vol.110
, pp. 2952-2967
-
-
Klein, S.1
Burke, L.E.2
Bray, G.A.3
Blair, S.4
Allison, D.B.5
Pi-Sunyer, X.6
-
6
-
-
23844454255
-
Metabolic syndrome: what is it and what are the implications?
-
D.I. Shaw W.L. Hall C.M. Williams Metabolic syndrome: what is it and what are the implications? Proc Nutr Soc 64 2005 349 357
-
(2005)
Proc Nutr Soc
, vol.64
, pp. 349-357
-
-
Shaw, D.I.1
Hall, W.L.2
Williams, C.M.3
-
7
-
-
0019762341
-
The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization
-
R.A. DeFronzo E. Jacot E. Jequier E. Maeder J. Wahren J.P. Felber The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization Diabetes 30 1981 1000 1007
-
(1981)
Diabetes
, vol.30
, pp. 1000-1007
-
-
DeFronzo, R.A.1
Jacot, E.2
Jequier, E.3
Maeder, E.4
Wahren, J.5
Felber, J.P.6
-
8
-
-
0025098765
-
Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy
-
G.I. Shulman D.L. Rothman T. Jue P. Stein R.A. DeFronzo R.G. Shulman Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy N Engl J Med 322 1990 223 228
-
(1990)
N Engl J Med
, vol.322
, pp. 223-228
-
-
Shulman, G.I.1
Rothman, D.L.2
Jue, T.3
Stein, P.4
DeFronzo, R.A.5
Shulman, R.G.6
-
11
-
-
0031894623
-
Development of insulin resistance in the JCR:LA-cp rat: role of triacylglycerols and effects of MEDICA 16
-
J.C. Russell G. Shillabeer J. Bar-Tana D.C. Lau M. Richardson L.M. Wenzel Development of insulin resistance in the JCR:LA-cp rat: role of triacylglycerols and effects of MEDICA 16 Diabetes 47 1998 770 778
-
(1998)
Diabetes
, vol.47
, pp. 770-778
-
-
Russell, J.C.1
Shillabeer, G.2
Bar-Tana, J.3
Lau, D.C.4
Richardson, M.5
Wenzel, L.M.6
-
12
-
-
0029787329
-
Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects
-
D.I. Phillips S. Caddy V. Ilic B.A. Fielding K.N. Frayn A.C. Borthwick Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects Metabolism 45 1996 947 950
-
(1996)
Metabolism
, vol.45
, pp. 947-950
-
-
Phillips, D.I.1
Caddy, S.2
Ilic, V.3
Fielding, B.A.4
Frayn, K.N.5
Borthwick, A.C.6
-
14
-
-
0033749620
-
Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply
-
C. Schmitz-Peiffer Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply Cell Signal 12 2000 583 594
-
(2000)
Cell Signal
, vol.12
, pp. 583-594
-
-
Schmitz-Peiffer, C.1
-
15
-
-
0023188325
-
After insulin binds
-
O.M. Rosen After insulin binds Science 237 1987 1452 1458
-
(1987)
Science
, vol.237
, pp. 1452-1458
-
-
Rosen, O.M.1
-
16
-
-
0033913213
-
Signaling pathways in insulin action: molecular targets of insulin resistance
-
J.E. Pessin A.R. Saltiel Signaling pathways in insulin action: molecular targets of insulin resistance J Clin Invest 106 2000 165 169
-
(2000)
J Clin Invest
, vol.106
, pp. 165-169
-
-
Pessin, J.E.1
Saltiel, A.R.2
-
17
-
-
0035936763
-
New perspectives into the molecular pathogenesis and treatment of type 2 diabetes
-
A.R. Saltiel New perspectives into the molecular pathogenesis and treatment of type 2 diabetes Cell 104 2001 517 529
-
(2001)
Cell
, vol.104
, pp. 517-529
-
-
Saltiel, A.R.1
-
18
-
-
0031913246
-
Mechanism of activation and function of protein kinase B
-
D.R. Alessi P. Cohen Mechanism of activation and function of protein kinase B Curr Opin Genet Dev 8 1998 55 62
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 55-62
-
-
Alessi, D.R.1
Cohen, P.2
-
19
-
-
0024244339
-
Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM
-
G.M. Reaven C. Hollenbeck C.Y. Jeng M.S. Wu Y.D. Chen Measurement of plasma glucose, free fatty acid, lactate, and insulin for 24 h in patients with NIDDM Diabetes 37 1988 1020 1024
-
(1988)
Diabetes
, vol.37
, pp. 1020-1024
-
-
Reaven, G.M.1
Hollenbeck, C.2
Jeng, C.Y.3
Wu, M.S.4
Chen, Y.D.5
-
20
-
-
0026468362
-
What if Minkowski had been ageusic? An alternative angle on diabetes
-
J.D. McGarry What if Minkowski had been ageusic? An alternative angle on diabetes Science 258 1992 766 770
-
(1992)
Science
, vol.258
, pp. 766-770
-
-
McGarry, J.D.1
-
22
-
-
0029084869
-
Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes
-
G. Boden X. Chen Effects of fat on glucose uptake and utilization in patients with non-insulin-dependent diabetes J Clin Invest 96 1995 1261 1268
-
(1995)
J Clin Invest
, vol.96
, pp. 1261-1268
-
-
Boden, G.1
Chen, X.2
-
23
-
-
0029046673
-
Effects of a 48-h fat infusion on insulin secretion and glucose utilization
-
G. Boden X. Chen J. Rosner M. Barton Effects of a 48-h fat infusion on insulin secretion and glucose utilization Diabetes 44 1995 1239 1242
-
(1995)
Diabetes
, vol.44
, pp. 1239-1242
-
-
Boden, G.1
Chen, X.2
Rosner, J.3
Barton, M.4
-
24
-
-
0032934826
-
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study
-
M. Krssak K. Falk Petersen A. Dresner L. DiPietro S.M. Vogel D.L. Rothman Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study Diabetologia 42 1999 113 116
-
(1999)
Diabetologia
, vol.42
, pp. 113-116
-
-
Krssak, M.1
Falk Petersen, K.2
Dresner, A.3
DiPietro, L.4
Vogel, S.M.5
Rothman, D.L.6
-
25
-
-
0037225537
-
Acute lowering of circulating fatty acids improves insulin secretion in a subset of type 2 diabetes subjects
-
E. Qvigstad I.L. Mostad K.S. Bjerve V.E. Grill Acute lowering of circulating fatty acids improves insulin secretion in a subset of type 2 diabetes subjects Am J Physiol Endocrinol Metab 284 2003 E129 E137
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
, pp. E129-E137
-
-
Qvigstad, E.1
Mostad, I.L.2
Bjerve, K.S.3
Grill, V.E.4
-
26
-
-
0035258482
-
Reducing plasma free fatty acids by acipimox improves glucose tolerance in high-fat fed mice
-
B. Ahren Reducing plasma free fatty acids by acipimox improves glucose tolerance in high-fat fed mice Acta Physiol Scand 171 2001 161 167
-
(2001)
Acta Physiol Scand
, vol.171
, pp. 161-167
-
-
Ahren, B.1
-
27
-
-
0030689043
-
Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding
-
N.D. Oakes G.J. Cooney S. Camilleri D.J. Chisholm E.W. Kraegen Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding Diabetes 46 1997 1768 1774
-
(1997)
Diabetes
, vol.46
, pp. 1768-1774
-
-
Oakes, N.D.1
Cooney, G.J.2
Camilleri, S.3
Chisholm, D.J.4
Kraegen, E.W.5
-
28
-
-
0029962282
-
Metabolic impairment precedes insulin resistance in skeletal muscle during high-fat feeding in rats
-
J.K. Kim J.K. Wi J.H. Youn Metabolic impairment precedes insulin resistance in skeletal muscle during high-fat feeding in rats Diabetes 45 1996 651 658
-
(1996)
Diabetes
, vol.45
, pp. 651-658
-
-
Kim, J.K.1
Wi, J.K.2
Youn, J.H.3
-
29
-
-
0026087478
-
Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid
-
L.H. Storlien A.B. Jenkins D.J. Chisholm W.S. Pascoe S. Khouri E.W. Kraegen Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid Diabetes 40 1991 280 289
-
(1991)
Diabetes
, vol.40
, pp. 280-289
-
-
Storlien, L.H.1
Jenkins, A.B.2
Chisholm, D.J.3
Pascoe, W.S.4
Khouri, S.5
Kraegen, E.W.6
-
30
-
-
0035149738
-
Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats
-
R.L. Dobbins L.S. Szczepaniak B. Bentley V. Esser J. Myhill J.D. McGarry Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats Diabetes 50 2001 123 130
-
(2001)
Diabetes
, vol.50
, pp. 123-130
-
-
Dobbins, R.L.1
Szczepaniak, L.S.2
Bentley, B.3
Esser, V.4
Myhill, J.5
McGarry, J.D.6
-
32
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
-
S.I. Itani N.B. Ruderman F. Schmieder G. Boden Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha Diabetes 51 2002 2005 2011
-
(2002)
Diabetes
, vol.51
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
Boden, G.4
-
33
-
-
0035405847
-
Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects
-
G. Boden B. Lebed M. Schatz C. Homko S. Lemieux Effects of acute changes of plasma free fatty acids on intramyocellular fat content and insulin resistance in healthy subjects Diabetes 50 2001 1612 1617
-
(2001)
Diabetes
, vol.50
, pp. 1612-1617
-
-
Boden, G.1
Lebed, B.2
Schatz, M.3
Homko, C.4
Lemieux, S.5
-
37
-
-
0033517284
-
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
-
I. Shimomura R.E. Hammer S. Ikemoto M.S. Brown J.L. Goldstein Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy Nature 401 1999 73 76
-
(1999)
Nature
, vol.401
, pp. 73-76
-
-
Shimomura, I.1
Hammer, R.E.2
Ikemoto, S.3
Brown, M.S.4
Goldstein, J.L.5
-
38
-
-
0036114844
-
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
-
K.F. Petersen E.A. Oral S. Dufour D. Befroy C. Ariyan C. Yu Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy J Clin Invest 109 2002 1345 1350
-
(2002)
J Clin Invest
, vol.109
, pp. 1345-1350
-
-
Petersen, K.F.1
Oral, E.A.2
Dufour, S.3
Befroy, D.4
Ariyan, C.5
Yu, C.6
-
40
-
-
34548626600
-
Effects of pioglitazone and metformin on intracellular lipid content in liver and skeletal muscle of individuals with type 2 diabetes mellitus
-
T. Teranishi T. Ohara K. Maeda M. Zenibayashi K. Kouyama Y. Hirota Effects of pioglitazone and metformin on intracellular lipid content in liver and skeletal muscle of individuals with type 2 diabetes mellitus Metabolism 56 2007 1418 1424
-
(2007)
Metabolism
, vol.56
, pp. 1418-1424
-
-
Teranishi, T.1
Ohara, T.2
Maeda, K.3
Zenibayashi, M.4
Kouyama, K.5
Hirota, Y.6
-
45
-
-
0035217707
-
Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes
-
B.H. Goodpaster J. He S. Watkins D.E. Kelley Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes J Clin Endocrinol Metab 86 2001 5755 5761
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5755-5761
-
-
Goodpaster, B.H.1
He, J.2
Watkins, S.3
Kelley, D.E.4
-
46
-
-
0036295566
-
Protein kinase C and lipid-induced insulin resistance in skeletal muscle
-
C. Schmitz-Peiffer Protein kinase C and lipid-induced insulin resistance in skeletal muscle Ann N Y Acad Sci 967 2002 146 157
-
(2002)
Ann N Y Acad Sci
, vol.967
, pp. 146-157
-
-
Schmitz-Peiffer, C.1
-
47
-
-
0026690888
-
Effects of high fat-feeding to rats on the interrelationship of body weight, plasma insulin, and fatty acyl-coenzyme A esters in liver and skeletal muscle
-
M.T. Chen L.N. Kaufman T. Spennetta E. Shrago Effects of high fat-feeding to rats on the interrelationship of body weight, plasma insulin, and fatty acyl-coenzyme A esters in liver and skeletal muscle Metabolism 41 1992 564 569
-
(1992)
Metabolism
, vol.41
, pp. 564-569
-
-
Chen, M.T.1
Kaufman, L.N.2
Spennetta, T.3
Shrago, E.4
-
48
-
-
0031753812
-
Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat
-
S.M. Chalkley M. Hettiarachchi D.J. Chisholm E.W. Kraegen Five-hour fatty acid elevation increases muscle lipids and impairs glycogen synthesis in the rat Metabolism 47 1998 1121 1126
-
(1998)
Metabolism
, vol.47
, pp. 1121-1126
-
-
Chalkley, S.M.1
Hettiarachchi, M.2
Chisholm, D.J.3
Kraegen, E.W.4
-
50
-
-
0033830528
-
Effects of individual fatty acids on glucose uptake and glycogen synthesis in soleus muscle in vitro
-
A.L. Thompson M.Y. Lim-Fraser E.W. Kraegen G.J. Cooney Effects of individual fatty acids on glucose uptake and glycogen synthesis in soleus muscle in vitro Am J Physiol Endocrinol Metab 279 2000 E577 E584
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
, pp. E577-E584
-
-
Thompson, A.L.1
Lim-Fraser, M.Y.2
Kraegen, E.W.3
Cooney, G.J.4
-
51
-
-
0030784947
-
Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA
-
N.D. Oakes K.S. Bell S.M. Furler S. Camilleri A.K. Saha N.B. Ruderman Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA Diabetes 46 1997 2022 2028
-
(1997)
Diabetes
, vol.46
, pp. 2022-2028
-
-
Oakes, N.D.1
Bell, K.S.2
Furler, S.M.3
Camilleri, S.4
Saha, A.K.5
Ruderman, N.B.6
-
53
-
-
0025339442
-
Palmitoyl-CoA and the acyl-CoA thioester of the carcinogenic peroxisome-proliferator ciprofibrate potentiate diacylglycerol-activated protein kinase C by decreasing the phosphatidylserine requirement of the enzyme
-
A. Orellana P.C. Hidalgo M.N. Morales D. Mezzano M. Bronfman Palmitoyl-CoA and the acyl-CoA thioester of the carcinogenic peroxisome-proliferator ciprofibrate potentiate diacylglycerol-activated protein kinase C by decreasing the phosphatidylserine requirement of the enzyme Eur J Biochem 190 1990 57 61
-
(1990)
Eur J Biochem
, vol.190
, pp. 57-61
-
-
Orellana, A.1
Hidalgo, P.C.2
Morales, M.N.3
Mezzano, D.4
Bronfman, M.5
-
54
-
-
0028267475
-
Effect of fatty acids and their acyl-CoA esters on protein kinase C activity in fibroblasts: possible implications in fatty acid oxidation defects
-
M. Nesher A. Boneh Effect of fatty acids and their acyl-CoA esters on protein kinase C activity in fibroblasts: possible implications in fatty acid oxidation defects Biochim Biophys Acta 1221 1994 66 72
-
(1994)
Biochim Biophys Acta
, vol.1221
, pp. 66-72
-
-
Nesher, M.1
Boneh, A.2
-
55
-
-
0037135536
-
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway
-
A.H. Merrill Jr. De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway J Biol Chem 277 2002 25843 25846
-
(2002)
J Biol Chem
, vol.277
, pp. 25843-25846
-
-
Merrill, A.H.1
-
56
-
-
0025123408
-
1,2-Diacylglycerol and ceramide levels in insulin-resistant tissues of the rat in vivo
-
J. Turinsky D.M. O'Sullivan B.P. Bayly 1,2-Diacylglycerol and ceramide levels in insulin-resistant tissues of the rat in vivo J Biol Chem 265 1990 16880 16885
-
(1990)
J Biol Chem
, vol.265
, pp. 16880-16885
-
-
Turinsky, J.1
O'Sullivan, D.M.2
Bayly, B.P.3
-
59
-
-
0037135626
-
The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind
-
Y.A. Hannun L.M. Obeid The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind J Biol Chem 277 2002 25847 25850
-
(2002)
J Biol Chem
, vol.277
, pp. 25847-25850
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
60
-
-
0025283928
-
An update of the enzymology and regulation of sphingomyelin metabolism
-
A.H. Merrill Jr. D.D. Jones An update of the enzymology and regulation of sphingomyelin metabolism Biochim Biophys Acta 1044 1990 1 12
-
(1990)
Biochim Biophys Acta
, vol.1044
, pp. 1-12
-
-
Merrill, A.H.1
Jones, D.D.2
-
61
-
-
0031750246
-
Pioglitazone time-dependently reduces tumour necrosis factor-alpha level in muscle and improves metabolic abnormalities in Wistar fatty rats
-
K. Murase H. Odaka M. Suzuki N. Tayuki H. Ikeda Pioglitazone time-dependently reduces tumour necrosis factor-alpha level in muscle and improves metabolic abnormalities in Wistar fatty rats Diabetologia 41 1998 257 264
-
(1998)
Diabetologia
, vol.41
, pp. 257-264
-
-
Murase, K.1
Odaka, H.2
Suzuki, M.3
Tayuki, N.4
Ikeda, H.5
-
62
-
-
31644443192
-
Ceramides in insulin resistance and lipotoxicity
-
S.A. Summers Ceramides in insulin resistance and lipotoxicity Prog Lipid Res 45 2006 42 72
-
(2006)
Prog Lipid Res
, vol.45
, pp. 42-72
-
-
Summers, S.A.1
-
63
-
-
0033588253
-
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
-
C. Schmitz-Peiffer D.L. Craig T.J. Biden Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate J Biol Chem 274 1999 24202 24210
-
(1999)
J Biol Chem
, vol.274
, pp. 24202-24210
-
-
Schmitz-Peiffer, C.1
Craig, D.L.2
Biden, T.J.3
-
64
-
-
0035133331
-
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
-
E. Hajduch A. Balendran I.H. Batty G.J. Litherland A.S. Blair C.P. Downes Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells Diabetologia 44 2001 173 183
-
(2001)
Diabetologia
, vol.44
, pp. 173-183
-
-
Hajduch, E.1
Balendran, A.2
Batty, I.H.3
Litherland, G.J.4
Blair, A.S.5
Downes, C.P.6
-
65
-
-
0038532298
-
A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
-
J.A. Chavez T.A. Knotts L.P. Wang G. Li R.T. Dobrowsky G.L. Florant A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids J Biol Chem 278 2003 10297 10303
-
(2003)
J Biol Chem
, vol.278
, pp. 10297-10303
-
-
Chavez, J.A.1
Knotts, T.A.2
Wang, L.P.3
Li, G.4
Dobrowsky, R.T.5
Florant, G.L.6
-
66
-
-
0030914330
-
Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat
-
C. Schmitz-Peiffer C.L. Browne N.D. Oakes A. Watkinson D.J. Chisholm E.W. Kraegen Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat Diabetes 46 1997 169 178
-
(1997)
Diabetes
, vol.46
, pp. 169-178
-
-
Schmitz-Peiffer, C.1
Browne, C.L.2
Oakes, N.D.3
Watkinson, A.4
Chisholm, D.J.5
Kraegen, E.W.6
-
67
-
-
0026334132
-
Enhanced stimulation of diacylglycerol and lipid synthesis by insulin in denervated muscle. Altered protein kinase C activity and possible link to insulin resistance
-
S.J. Heydrick N.B. Rudermain T.G. Kurowski H.B. Adams K.S. Chen Enhanced stimulation of diacylglycerol and lipid synthesis by insulin in denervated muscle. Altered protein kinase C activity and possible link to insulin resistance Diabetes 40 1991 1707 1711
-
(1991)
Diabetes
, vol.40
, pp. 1707-1711
-
-
Heydrick, S.J.1
Rudermain, N.B.2
Kurowski, T.G.3
Adams, H.B.4
Chen, K.S.5
-
68
-
-
0027367280
-
Decreased expression of protein kinase-C alpha, beta, and epsilon in soleus muscle of Zucker obese (fa/fa) rats
-
D.R. Cooper J.E. Watson M.L. Dao Decreased expression of protein kinase-C alpha, beta, and epsilon in soleus muscle of Zucker obese ( fa / fa ) rats Endocrinology 133 1993 2241 2247
-
(1993)
Endocrinology
, vol.133
, pp. 2241-2247
-
-
Cooper, D.R.1
Watson, J.E.2
Dao, M.L.3
-
69
-
-
0028200530
-
Lipid abnormalities in tissues of the KKAy mouse: effects of pioglitazone on malonyl-CoA and diacylglycerol
-
A.K. Saha T.G. Kurowski J.R. Colca N.B. Ruderman Lipid abnormalities in tissues of the KKAy mouse: effects of pioglitazone on malonyl-CoA and diacylglycerol Am J Physiol 267 1994 E95 E101
-
(1994)
Am J Physiol
, vol.267
, pp. E95-E101
-
-
Saha, A.K.1
Kurowski, T.G.2
Colca, J.R.3
Ruderman, N.B.4
-
70
-
-
0032813243
-
Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats — effects of feeding
-
X. Qu J.P. Seale R. Donnelly Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats — effects of feeding J Endocrinol 162 1999 207 214
-
(1999)
J Endocrinol
, vol.162
, pp. 207-214
-
-
Qu, X.1
Seale, J.P.2
Donnelly, R.3
-
71
-
-
0029070256
-
Insulin increases mRNA levels of protein kinase C-alpha and -beta in rat adipocytes and protein kinase C-alpha, -beta and -theta in rat skeletal muscle
-
A. Avignon M.L. Standaert K. Yamada H. Mischak B. Spencer R.V. Farese Insulin increases mRNA levels of protein kinase C-alpha and -beta in rat adipocytes and protein kinase C-alpha, -beta and -theta in rat skeletal muscle Biochem J 308 Pt 1 1995 181 187
-
(1995)
Biochem J
, vol.308
, Issue.Pt 1
, pp. 181-187
-
-
Avignon, A.1
Standaert, M.L.2
Yamada, K.3
Mischak, H.4
Spencer, B.5
Farese, R.V.6
-
72
-
-
2942517752
-
Divergent and convergent signaling by the diacylglycerol second messenger pathway in mammals
-
N. Brose A. Betz H. Wegmeyer Divergent and convergent signaling by the diacylglycerol second messenger pathway in mammals Curr Opin Neurobiol 14 2004 328 340
-
(2004)
Curr Opin Neurobiol
, vol.14
, pp. 328-340
-
-
Brose, N.1
Betz, A.2
Wegmeyer, H.3
-
73
-
-
33845962013
-
Diacylglycerol, when simplicity becomes complex
-
S. Carrasco I. Merida Diacylglycerol, when simplicity becomes complex Trends Biochem Sci 32 2007 27 36
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 27-36
-
-
Carrasco, S.1
Merida, I.2
-
74
-
-
0037085450
-
Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis
-
G. Haemmerle R. Zimmermann M. Hayn C. Theussl G. Waeg E. Wagner Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis J Biol Chem 277 2002 4806 4815
-
(2002)
J Biol Chem
, vol.277
, pp. 4806-4815
-
-
Haemmerle, G.1
Zimmermann, R.2
Hayn, M.3
Theussl, C.4
Waeg, G.5
Wagner, E.6
-
75
-
-
10344262633
-
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
-
C.M. Jenkins D.J. Mankuso W. Yan H.F. Sims B. Gibson R.W. Gross Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities J Biol Chem 279 2004 48968 48975
-
(2004)
J Biol Chem
, vol.279
, pp. 48968-48975
-
-
Jenkins, C.M.1
Mankuso, D.J.2
Yan, W.3
Sims, H.F.4
Gibson, B.5
Gross, R.W.6
-
76
-
-
8744297386
-
Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis
-
J.A. Villena S. Roy E. Sarkadi-Nagy K.H. Kim H.S. Sul Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis J Biol Chem 279 2004 47066 47075
-
(2004)
J Biol Chem
, vol.279
, pp. 47066-47075
-
-
Villena, J.A.1
Roy, S.2
Sarkadi-Nagy, E.3
Kim, K.H.4
Sul, H.S.5
-
79
-
-
0023764824
-
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
-
Y. Nishizuka The molecular heterogeneity of protein kinase C and its implications for cellular regulation Nature 334 1988 661 665
-
(1988)
Nature
, vol.334
, pp. 661-665
-
-
Nishizuka, Y.1
-
80
-
-
0028811653
-
Protein kinase C: structure, function, and regulation
-
A.C. Newton Protein kinase C: structure, function, and regulation J Biol Chem 270 1995 28495 28498
-
(1995)
J Biol Chem
, vol.270
, pp. 28495-28498
-
-
Newton, A.C.1
-
81
-
-
0021227676
-
The role of protein kinase C in cell surface signal transduction and tumour promotion
-
Y. Nishizuka The role of protein kinase C in cell surface signal transduction and tumour promotion Nature 308 1984 693 698
-
(1984)
Nature
, vol.308
, pp. 693-698
-
-
Nishizuka, Y.1
-
82
-
-
0026451081
-
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Y. Nishizuka Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C Science 258 1992 607 614
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
83
-
-
0029060391
-
Protein kinase C and lipid signaling for sustained cellular responses
-
Y. Nishizuka Protein kinase C and lipid signaling for sustained cellular responses Faseb J 9 1995 484 496
-
(1995)
Faseb J
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
84
-
-
0027942711
-
Expression of the major isoenzyme of protein kinase-C in skeletal muscle, nPKC theta, varies with muscle type and in response to fructose-induced insulin resistance
-
R. Donnelly M.J. Reed S. Azhar G.M. Reaven Expression of the major isoenzyme of protein kinase-C in skeletal muscle, nPKC theta, varies with muscle type and in response to fructose-induced insulin resistance Endocrinology 135 1994 2369 2374
-
(1994)
Endocrinology
, vol.135
, pp. 2369-2374
-
-
Donnelly, R.1
Reed, M.J.2
Azhar, S.3
Reaven, G.M.4
-
85
-
-
0345086474
-
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
-
M.E. Griffin M.J. Marcucci G.W. Cline K. Bell N. Barucci D. Lee Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade Diabetes 48 1999 1270 1274
-
(1999)
Diabetes
, vol.48
, pp. 1270-1274
-
-
Griffin, M.E.1
Marcucci, M.J.2
Cline, G.W.3
Bell, K.4
Barucci, N.5
Lee, D.6
-
86
-
-
0033695810
-
Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotubes
-
G. Bandyopadhyay Y. Kanoh M.P. Sajan M.L. Standaert R.V. Farese Effects of adenoviral gene transfer of wild-type, constitutively active, and kinase-defective protein kinase C-lambda on insulin-stimulated glucose transport in L6 myotubes Endocrinology 141 2000 4120 4127
-
(2000)
Endocrinology
, vol.141
, pp. 4120-4127
-
-
Bandyopadhyay, G.1
Kanoh, Y.2
Sajan, M.P.3
Standaert, M.L.4
Farese, R.V.5
-
87
-
-
0025292249
-
Increased protein kinase C activity is linked to reduced insulin receptor autophosphorylation in liver of starved rats
-
A. Karasik P.L. Rothenberg K. Yamada M.F. White C.R. Kahn Increased protein kinase C activity is linked to reduced insulin receptor autophosphorylation in liver of starved rats J Biol Chem 265 1990 10226 10231
-
(1990)
J Biol Chem
, vol.265
, pp. 10226-10231
-
-
Karasik, A.1
Rothenberg, P.L.2
Yamada, K.3
White, M.F.4
Kahn, C.R.5
-
88
-
-
0030733054
-
Protein kinase C (PKC) epsilon enhances the inhibitory effect of TNF alpha on insulin signaling in HEK293 cells
-
M. Kellerer J. Mushack H. Mischak H.U. Haring Protein kinase C (PKC) epsilon enhances the inhibitory effect of TNF alpha on insulin signaling in HEK293 cells FEBS Lett 418 1997 119 122
-
(1997)
FEBS Lett
, vol.418
, pp. 119-122
-
-
Kellerer, M.1
Mushack, J.2
Mischak, H.3
Haring, H.U.4
-
89
-
-
6344258131
-
Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance
-
Y.F. Liu A. Herschkovitz S. Boura-Halfon D. Ronen K. Paz D. Leroith Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance Mol Cell Biol 24 2004 9668 9681
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9668-9681
-
-
Liu, Y.F.1
Herschkovitz, A.2
Boura-Halfon, S.3
Ronen, D.4
Paz, K.5
Leroith, D.6
-
90
-
-
0030669392
-
A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
-
K. Paz R. Hemi D. LeRoith A. Karasik E. Elhanany H. Kanety A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation J Biol Chem 272 1997 29911 29918
-
(1997)
J Biol Chem
, vol.272
, pp. 29911-29918
-
-
Paz, K.1
Hemi, R.2
LeRoith, D.3
Karasik, A.4
Elhanany, E.5
Kanety, H.6
-
91
-
-
0028023002
-
Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling
-
J.F. Tanti T. Gremeaux E. van Obberghen Y. Le Marchand-Brustel Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling J Biol Chem 269 1994 6051 6057
-
(1994)
J Biol Chem
, vol.269
, pp. 6051-6057
-
-
Tanti, J.F.1
Gremeaux, T.2
van Obberghen, E.3
Le Marchand-Brustel, Y.4
-
93
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
S.H. Um F. Frigerio M. Watanabe F. Picard M. Joaquin M. Sticker Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity Nature 431 2004 200 205
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
-
96
-
-
31044433308
-
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents
-
K. Morino K.F. Petersen S. Dufour D. Befroy J. Frattini N. Shatzkes Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents J Clin Invest 115 2005 3587 3593
-
(2005)
J Clin Invest
, vol.115
, pp. 3587-3593
-
-
Morino, K.1
Petersen, K.F.2
Dufour, S.3
Befroy, D.4
Frattini, J.5
Shatzkes, N.6
-
97
-
-
15844389443
-
Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action
-
I. Mothe E. Van Obberghen Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action J Biol Chem 271 1996 11222 11227
-
(1996)
J Biol Chem
, vol.271
, pp. 11222-11227
-
-
Mothe, I.1
Van Obberghen, E.2
-
98
-
-
0037059330
-
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
-
V. Aguirre E.D. Werner J. Giraud Y.H. Lee S.E. Shoelson M.F. White Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action J Biol Chem 277 2002 1531 1537
-
(2002)
J Biol Chem
, vol.277
, pp. 1531-1537
-
-
Aguirre, V.1
Werner, E.D.2
Giraud, J.3
Lee, Y.H.4
Shoelson, S.E.5
White, M.F.6
-
99
-
-
2942623679
-
Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1
-
K. Moeschel A. Beck C. Weigert R. Lammers H. Kalbacher W. Voelter Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1 J Biol Chem 279 2004 25157 25163
-
(2004)
J Biol Chem
, vol.279
, pp. 25157-25163
-
-
Moeschel, K.1
Beck, A.2
Weigert, C.3
Lammers, R.4
Kalbacher, H.5
Voelter, W.6
-
100
-
-
0033515459
-
Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway
-
J. Li K. DeFea R.A. Roth Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway J Biol Chem 274 1999 9351 9356
-
(1999)
J Biol Chem
, vol.274
, pp. 9351-9356
-
-
Li, J.1
DeFea, K.2
Roth, R.A.3
-
101
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
C. Yu Y. Chen G.W. Cline D. Zhang H. Zong Y. Wang Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle J Biol Chem 277 2002 50230 50236
-
(2002)
J Biol Chem
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
Zhang, D.4
Zong, H.5
Wang, Y.6
-
102
-
-
0030678164
-
Reversal of chronic alterations of skeletal muscle protein kinase C from fat-fed rats by BRL-49653
-
C. Schmitz-Peiffer N.D. Oakes C.L. Browne E.W. Kraegen T.J. Biden Reversal of chronic alterations of skeletal muscle protein kinase C from fat-fed rats by BRL-49653 Am J Physiol 273 1997 E915 E921
-
(1997)
Am J Physiol
, vol.273
, pp. E915-E921
-
-
Schmitz-Peiffer, C.1
Oakes, N.D.2
Browne, C.L.3
Kraegen, E.W.4
Biden, T.J.5
-
104
-
-
0035340548
-
Increased protein kinase C theta in skeletal muscle of diabetic patients
-
S.I. Itani W.J. Pories K.G. Macdonald G.L. Dohm Increased protein kinase C theta in skeletal muscle of diabetic patients Metabolism 50 2001 553 557
-
(2001)
Metabolism
, vol.50
, pp. 553-557
-
-
Itani, S.I.1
Pories, W.J.2
Macdonald, K.G.3
Dohm, G.L.4
-
107
-
-
0036889152
-
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition
-
L.E. Hammond P.A. Gallagher S. Wang S. Hiller K.D. Kluckman E.L. Posey-Marcos Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition Mol Cell Biol 22 2002 8204 8214
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8204-8214
-
-
Hammond, L.E.1
Gallagher, P.A.2
Wang, S.3
Hiller, S.4
Kluckman, K.D.5
Posey-Marcos, E.L.6
-
108
-
-
13144281703
-
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
-
S. Cases S.J. Smith Y.W. Zheng H.M. Myers S.R. Lear E. Sande Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis Proc Natl Acad Sci U S A 95 1998 13018 13023
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13018-13023
-
-
Cases, S.1
Smith, S.J.2
Zheng, Y.W.3
Myers, H.M.4
Lear, S.R.5
Sande, E.6
-
109
-
-
0035914356
-
Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
-
S. Cases S.J. Stone P. Zhou E. Yen B. Tow K.D. Lardizabal Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members J Biol Chem 276 2001 38870 38876
-
(2001)
J Biol Chem
, vol.276
, pp. 38870-38876
-
-
Cases, S.1
Stone, S.J.2
Zhou, P.3
Yen, E.4
Tow, B.5
Lardizabal, K.D.6
-
110
-
-
0034128280
-
Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase
-
R.V. Farese Jr. S. Cases S.J. Smith Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase Curr Opin Lipidol 11 2000 229 234
-
(2000)
Curr Opin Lipidol
, vol.11
, pp. 229-234
-
-
Farese, R.V.1
Cases, S.2
Smith, S.J.3
-
112
-
-
0036228339
-
Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1
-
H.C. Chen S.J. Smith Z. Ladha D.R. Jensen L.D. Ferreira L.K. Pulawa Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1 J Clin Invest 109 2002 1049 1055
-
(2002)
J Clin Invest
, vol.109
, pp. 1049-1055
-
-
Chen, H.C.1
Smith, S.J.2
Ladha, Z.3
Jensen, D.R.4
Ferreira, L.D.5
Pulawa, L.K.6
-
113
-
-
2542610041
-
Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1
-
H.C. Chen M. Rao M.P. Sajan M. Standaert Y. Kanoh A. Miura Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1 Diabetes 53 2004 1445 1451
-
(2004)
Diabetes
, vol.53
, pp. 1445-1451
-
-
Chen, H.C.1
Rao, M.2
Sajan, M.P.3
Standaert, M.4
Kanoh, Y.5
Miura, A.6
-
114
-
-
14744304497
-
Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice
-
H.C. Chen R.V. Farese Jr. Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice Arterioscler Thromb Vasc Biol 25 2005 482 486
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 482-486
-
-
Chen, H.C.1
Farese, R.V.2
-
115
-
-
0036828913
-
Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue
-
H.C. Chen S.J. Stone P. Zhou K.K. Buhman R.V. Farese Jr Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue Diabetes 51 2002 3189 3195
-
(2002)
Diabetes
, vol.51
, pp. 3189-3195
-
-
Chen, H.C.1
Stone, S.J.2
Zhou, P.3
Buhman, K.K.4
Farese, R.V.5
-
116
-
-
0034103658
-
Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
-
S.J. Smith S. Cases D.R. Jensen H.C. Chen E. Sande B. Tow Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat Nat Genet 25 2000 87 90
-
(2000)
Nat Genet
, vol.25
, pp. 87-90
-
-
Smith, S.J.1
Cases, S.2
Jensen, D.R.3
Chen, H.C.4
Sande, E.5
Tow, B.6
-
117
-
-
0038481184
-
Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase 1
-
H.C. Chen D.R. Jensen H.M. Myers R.H. Eckel R.V. Farese Jr Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase 1 J Clin Invest 111 2003 1715 1722
-
(2003)
J Clin Invest
, vol.111
, pp. 1715-1722
-
-
Chen, H.C.1
Jensen, D.R.2
Myers, H.M.3
Eckel, R.H.4
Farese, R.V.5
-
118
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
J. Fruebis T.S. Tsao S. Javorschi D. Ebbets-Reed M.R.. Erickson F.T. Yen Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice Proc Natl Acad Sci U S A 98 2001 2005 2010
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
Tsao, T.S.2
Javorschi, S.3
Ebbets-Reed, D.4
Erickson, M.R..5
Yen, F.T.6
-
120
-
-
24744443740
-
The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters
-
C.L. Yen M. Monetti B.J. Burri R.V. Farese Jr The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters J Lipid Res 46 2005 1502 1511
-
(2005)
J Lipid Res
, vol.46
, pp. 1502-1511
-
-
Yen, C.L.1
Monetti, M.2
Burri, B.J.3
Farese, R.V.4
-
121
-
-
34249894505
-
Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
-
L. Liu Y. Zhang N. Chen X. Shi B. Tsang Y.H. Yu Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance J Clin Invest 117 2007 1679 1689
-
(2007)
J Clin Invest
, vol.117
, pp. 1679-1689
-
-
Liu, L.1
Zhang, Y.2
Chen, N.3
Shi, X.4
Tsang, B.5
Yu, Y.H.6
-
122
-
-
34249915334
-
Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance
-
S. Schenk J.F. Horowitz Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance J Clin Invest 117 2007 1690 1698
-
(2007)
J Clin Invest
, vol.117
, pp. 1690-1698
-
-
Schenk, S.1
Horowitz, J.F.2
-
124
-
-
0142164965
-
Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes
-
J.A. Chavez S.A. Summers Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes Arch Biochem Biophys 419 2003 101 109
-
(2003)
Arch Biochem Biophys
, vol.419
, pp. 101-109
-
-
Chavez, J.A.1
Summers, S.A.2
-
126
-
-
14644435061
-
Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes
-
M. Gaster A.C. Rustan H. Beck-Nielsen Differential utilization of saturated palmitate and unsaturated oleate: evidence from cultured myotubes Diabetes 54 2005 648 656
-
(2005)
Diabetes
, vol.54
, pp. 648-656
-
-
Gaster, M.1
Rustan, A.C.2
Beck-Nielsen, H.3
-
127
-
-
0017303551
-
Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols
-
R. Coleman R.M. Bell Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols J Biol Chem 251 1976 4537 4543
-
(1976)
J Biol Chem
, vol.251
, pp. 4537-4543
-
-
Coleman, R.1
Bell, R.M.2
-
128
-
-
0025649465
-
Triacylglycerol synthesis and diacylglycerol acyltransferase activity during skeletal myogenesis
-
V.S. Sauro K.P. Strickland Triacylglycerol synthesis and diacylglycerol acyltransferase activity during skeletal myogenesis Biochem Cell Biol 68 1990 1393 1401
-
(1990)
Biochem Cell Biol
, vol.68
, pp. 1393-1401
-
-
Sauro, V.S.1
Strickland, K.P.2
-
129
-
-
0035081372
-
Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study
-
B. Vessby M. Unsitupa K. Hermansen G. Riccardi A.A. Rivellese L.C. Tapsell Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study Diabetologia 44 2001 312 319
-
(2001)
Diabetologia
, vol.44
, pp. 312-319
-
-
Vessby, B.1
Unsitupa, M.2
Hermansen, K.3
Riccardi, G.4
Rivellese, A.A.5
Tapsell, L.C.6
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