Free fatty acid-induced insulin resistance is associated with activation of protein kinase C θ and alterations in the insulin signaling cascade

Diabetes

Volumn 48, Issue 6, 2000, Pages 1270-1274

  Griffin, Margaret E ^a,b   Marcucci, Melissa J ^b   Cline, Gary W ^a   Bell, Kim ^d   Barucci, Nicole ^b   Lee, Dennis ^a   Goodyear, Laurie J ^c   Kraegen, Edward W ^d   White, Morris F ^b,c   Shulman, Gerald I ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c JOSLIN DIABETES CENTER   (United States)

^d GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCOSE OXIDATION; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; INSULIN RESISTANCE; MALE; MUSCLE METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; DEOXYGLUCOSE; ENZYME ACTIVATION; FATTY ACIDS, NONESTERIFIED; INSULIN; INSULIN RESISTANCE; ISOENZYMES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MUSCLE, SKELETAL; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TYROSINE; ZINC FINGERS;

EID: 0345086474     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.6.1270     Document Type: Article

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