Reversal of chronic alterations of skeletal muscle protein kinase C from fat-fed rats by BRL-49653

American Journal of Physiology - Endocrinology and Metabolism

Volumn 273, Issue 5 36-5, 1997, Pages

  Schmitz Peiffer, Carsten ^a   Oakes, Nicholas D ^a,b   Browne, Carol L ^a   Kraegen, Edward W ^a   Biden, Trevor J ^a  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Insulin resistance; Thiazolidinedione

Indexed keywords

INSULIN; PROTEIN KINASE C; ROSIGLITAZONE; THIAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME ANALYSIS; ENZYME REGULATION; FAT INTAKE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID ANALYSIS; MALE; MUSCLE METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE;

EID: 0030678164     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1997.273.5.e915     Document Type: Article

References (15)

1. 2+- and phospholipid-activated protein kinase (protein kinase G). J. Biol. Chem. 259: 8743-8747, 1984.
2. Avignon, A., K. Yamada, X. P. Zhou, B. Spencer, O. Cardona, S. Sabasiddique, L. Galloway, M. L. Standaert, and R. V. Farese. Chronic activation of protein kinase C in soleus muscles and other tissues of insulin-resistant type II diabetic Goto-Kakizaki (GK), obese/aged, and obese/Zucker rats - a mechanism for inhibiting glycogen synthesis. Diabetes 45: 1396-1404, 1996.
3. Bahr, M., M. Spelleken, M. Bock, M. Vonholtey, R. Kiehn, and J. Eckel. Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes. Diabetologia 39: 766-774, 1996.
4. Bandyopadhyay, G., M. L. Standaert, L. M. Zhao, B. Z. Yu, A. Avignon, L. Galloway, P. Karnam, J. Moscat, and R. V. Farese. Activation of protein kinase C (α, β, and ζ) by insulin in 3T3/L1 cells-transfection studies suggest a role for PKC-ζ in glucose transport. J. Biol. Chem. 272: 2551-2558, 1997.
5. Blackshear, P. J. The role (or lack thereof) of protein kinase-C in insulin action. In: Molecular Biology of Diabetes, Part II, edited by B. Draznin and D. Leroith. Totowa, NJ: Humana, 1994, p.229-244.
6. Bollag, G. E., R. A. Roth, J. Beaudoin, R. D. Mochly, and D. J. Koshland. Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity. Proc, Natl. Acad. Sci. USA 83: 5822-5824, 1986.
7. Borkman, M., L. H. Storlien, D. A. Pan, A. B. Jenkins, D. J. Chisholm, and L. V. Campbell. The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids. N. Engl. J. Med. 328: 238-244, 1993.
8. Bronfman, M., M. N. Morales, and A. Orellana. Diacylglycerol activation of protein kinase C is modulated by long-chain acyl-CoA. Biochem. Biophys. Res. Commun. 152: 987-992, 1988.
9. Cawthorne, M. A., C. A. Lister, J. C. Holder, D. M. Kirkham, P. W. Young, B. C. Cantello, R. M. Hindley, and S. A. Smith. Anti-hyperglycaemic efficacy of BRL 49653, a highly potent thiazolidinedione, in animal models of non-insulin dependent diabetes (Abstract). Diabetes 42, Suppl. 1: 204A, 1993.
10. Chen, K. S., S. J. Heydrick, M. L. Brown, J. C. Friel, and N. B. Ruderman. Insulin increases a biochemically distinct pool of diacylglycerol in the rat soleus muscle. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E479-E485, 1994.
11. Chen, K. S., S. Heydrick, T. Kurowski, and N. B. Ruderman. Diacylglycerol-protein kinase C signalling in skeletal muscle: a possible link to insulin resistance. Trans. Assoc. Am. Phys. 104: 206-212, 1991.
12. Chida, K., N. Kato, and T. Kurohi. Down regulation of phorbol diester receptors by proteolytic degradation of protein kinase C in a cultured cell line of fetal rat skin keratinocytes. J. Biol. Chem. 261: 13013-13018, 1986.
13. Chin, J. E., M. Dickens, J. T. Tavare, and R. A. Roth. Overexpression of protein kinase-C isoenzymes-alpha, beta-I, gamma and epsilon in cells overexpressing the insulin receptor-effects on receptor phosphorylation and signalling. J. Biol. Chem. 268: 6338-6347, 1993.
14. Chin, J. E., F. Liu, and R. A. Roth. Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1. Mol. Endocrinol. 8: 51-58, 1994.
15. Considine, R. V., and J. F. Caro. Protein kinase-C - mediator or inhibitor of insulin action. J. Cell. Biochem. 52: 8-13, 1993.