Transition state structure of 5′-methylthioadenosine/S- adenosylhomocysteine nucleosidase from Escherichia coli and its similarity to transition state analogues

Biochemistry

Volumn 44, Issue 35, 2005, Pages 11647-11659

  Singh, Vipender ^a   Lee, Jeffrey E ^b   Núñez, Sara ^a   Howell, P Lynne ^b   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CATALYSIS; CONFORMATIONS; ISOTOPES;

ANTIMICROBIAL DRUG DESIGN; KINETIC ISOTOPE EFFECTS (KIES); POLYAMINE METABOLISM;

ESCHERICHIA COLI;

5' METHYLTHIOADENOSINE; ADENINE; ADENOSINE DERIVATIVE; ADENOSYLHOMOCYSTEINE NUCLEOSIDASE; ANTIINFECTIVE AGENT; CARBENOID; CARBON; METHYL GROUP; NUCLEOSIDASE; POLYAMINE; RIBOOXACARBENIUM ION; S ADENOSYLHOMOCYSTEINE; SULFUR; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CONFORMATION; CONJUGATION; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; ELECTRICITY; ESCHERICHIA COLI; KINETICS; MODEL; NONHUMAN; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYAMINE METABOLISM; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

CARBON RADIOISOTOPES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; N-GLYCOSYL HYDROLASES; NITROGEN ISOTOPES; TRITIUM;

ESCHERICHIA COLI;

EID: 23944446462     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050863a     Document Type: Article

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