-
1
-
-
42149136987
-
-
Alzheimer A. Uber eine eigenartige erkrankung der hirnrinde. Allg. Zeitschr. Psychiatr Psychiatr-Gerichtl Med 109: 146-148 (1907).
-
Alzheimer A. Uber eine eigenartige erkrankung der hirnrinde. Allg. Zeitschr. Psychiatr Psychiatr-Gerichtl Med 109: 146-148 (1907).
-
-
-
-
2
-
-
0021256895
-
Alzheimer's disease: Initial report of purification and characterization of a novel cerebrovascular amyloid protein
-
Glenner GG and Wong CW. Alzheimer's disease: initial report of purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 120: 885-890 (1984).
-
(1984)
Biochem Biophys Res Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
3
-
-
0023132387
-
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
-
Goldgaber D, Lerman MI, McBride OW, Saffiotti U and Gajdusek DC. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science 235: 877-880 (1987).
-
(1987)
Science
, vol.235
, pp. 877-880
-
-
Goldgaber, D.1
Lerman, M.I.2
McBride, O.W.3
Saffiotti, U.4
Gajdusek, D.C.5
-
4
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736 (1987).
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
-
5
-
-
2142777413
-
Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptide
-
Robakis NK, Ramakrishna N, Wolfe G and Wiesniewski HM. Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptide. Proc Natl Acad Sci USA 854: 4190-4194 (1987).
-
(1987)
Proc Natl Acad Sci USA
, vol.854
, pp. 4190-4194
-
-
Robakis, N.K.1
Ramakrishna, N.2
Wolfe, G.3
Wiesniewski, H.M.4
-
6
-
-
0023109592
-
Amyloid beta protein gene: CDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
Tanzi RE, Gusella JF, Watkins PC, Bruns GA, St Georges-Hyslop P, Van Keuren ML, et al. Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science 235: 880-884 (1987).
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
Bruns, G.A.4
St Georges-Hyslop, P.5
Van Keuren, M.L.6
-
7
-
-
0842309491
-
β-secretase inhibition for the treatment of Alzheimer's disease-Promising challenge. Trends in Pharm
-
Citron M. β-secretase inhibition for the treatment of Alzheimer's disease-Promising challenge. Trends in Pharm Sci 25: 92-97 (2004).
-
(2004)
Sci
, vol.25
, pp. 92-97
-
-
Citron, M.1
-
8
-
-
0035736326
-
Endogenous β-amyloid production in presenilin-deficient embryonic mouse fibroblasts
-
Armogida M, Petit A, Vincent B, Scarzello S, Alves da Costa C and Checler F. Endogenous β-amyloid production in presenilin-deficient embryonic mouse fibroblasts. Nature Cell Biol 3: 1030-1033 (2001).
-
(2001)
Nature Cell Biol
, vol.3
, pp. 1030-1033
-
-
Armogida, M.1
Petit, A.2
Vincent, B.3
Scarzello, S.4
Alves da Costa, C.5
Checler, F.6
-
9
-
-
0036727463
-
Presenilins are not required for Ab42 production in the early secretory pathway
-
Wilson CA, Doms RW, Zheng H and Lee VMY. Presenilins are not required for Ab42 production in the early secretory pathway. Nature Neurosci 5: 849-855 (2002).
-
(2002)
Nature Neurosci
, vol.5
, pp. 849-855
-
-
Wilson, C.A.1
Doms, R.W.2
Zheng, H.3
Lee, V.M.Y.4
-
10
-
-
33644838251
-
A presenilin-independent aspartyl protease prefers the gamma-42 site cleavage
-
Lai MT, Crouthamel MC, DiMuzio J, Pietrak BL, Donoviel DB, Bernstein A, et al. A presenilin-independent aspartyl protease prefers the gamma-42 site cleavage. J Neurochem 96: 118-125 (2006).
-
(2006)
J Neurochem
, vol.96
, pp. 118-125
-
-
Lai, M.T.1
Crouthamel, M.C.2
DiMuzio, J.3
Pietrak, B.L.4
Donoviel, D.B.5
Bernstein, A.6
-
11
-
-
33745614108
-
The γ-secretase complex: Membrane-embedded proteolytic ensemble
-
Wolfe MS. The γ-secretase complex: membrane-embedded proteolytic ensemble. Biochemistry 45: 7931-7939 (2006).
-
(2006)
Biochemistry
, vol.45
, pp. 7931-7939
-
-
Wolfe, M.S.1
-
12
-
-
0242412482
-
Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional γ-secretase inhibitor
-
Searfoss GH, Joran WH, Calligaro DO, Galbreath EJ, Schirtzinger LM, Berridge BR, et al. Adipsin, a biomarker of gastrointestinal toxicity mediated by a functional γ-secretase inhibitor. J Biol Chem 278: 46107-46116 (2003).
-
(2003)
J Biol Chem
, vol.278
, pp. 46107-46116
-
-
Searfoss, G.H.1
Joran, W.H.2
Calligaro, D.O.3
Galbreath, E.J.4
Schirtzinger, L.M.5
Berridge, B.R.6
-
13
-
-
11144355129
-
Chronic treatment with the γ-secretase inhibitor LY-411,575 inhibits β-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation
-
Wong GT, Manfra D, Poulet FM, Zhang Q, Josien H, Bara T, et al. Chronic treatment with the γ-secretase inhibitor LY-411,575 inhibits β-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation. J Biol Chem 279: 12876-12882 (2004).
-
(2004)
J Biol Chem
, vol.279
, pp. 12876-12882
-
-
Wong, G.T.1
Manfra, D.2
Poulet, F.M.3
Zhang, Q.4
Josien, H.5
Bara, T.6
-
14
-
-
0035005101
-
New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting notch cleavage
-
Petit A, Bihel F, Alves da Costa C, Pourquié O, Checler F and Kraus JL. New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting notch cleavage. Nature Cell Biol 3: 507-511 (2001).
-
(2001)
Nature Cell Biol
, vol.3
, pp. 507-511
-
-
Petit, A.1
Bihel, F.2
Alves da Costa, C.3
Pourquié, O.4
Checler, F.5
Kraus, J.L.6
-
15
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
-
Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, et al. A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity. Nature 414: 212-216 (2001).
-
(2001)
Nature
, vol.414
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
Sagi, S.A.4
Wang, R.5
Pietrzik, C.U.6
-
16
-
-
0142059785
-
Gleevec inhibits β-amyloid production but not Notch cleavage
-
Netzer WJ, Dou F, Cai D, Veach D, Jean S, Li Y, et al. Gleevec inhibits β-amyloid production but not Notch cleavage. Proc Natl Acad Sci USA 100: 12444-12449 (2003).
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12444-12449
-
-
Netzer, W.J.1
Dou, F.2
Cai, D.3
Veach, D.4
Jean, S.5
Li, Y.6
-
17
-
-
0034614384
-
Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells
-
Palacino JJ, Berechid BE, Alexander P, Eckman C, Younkin S, Nye JS, et al. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells. J Biol Chem 275: 215-222 (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 215-222
-
-
Palacino, J.J.1
Berechid, B.E.2
Alexander, P.3
Eckman, C.4
Younkin, S.5
Nye, J.S.6
-
18
-
-
16544373574
-
Amyloid precursor protein compartmentalization restricts β-amyloid production: Therapeutic targets based on BACE compartmentalization
-
Gandhi S, Refolo LM and Sambamurti K. Amyloid precursor protein compartmentalization restricts β-amyloid production: therapeutic targets based on BACE compartmentalization. J Mol Neurosci 24: 137-144 (2004).
-
(2004)
J Mol Neurosci
, vol.24
, pp. 137-144
-
-
Gandhi, S.1
Refolo, L.M.2
Sambamurti, K.3
-
20
-
-
0029027854
-
Truncated forms of the human prion protein in normal brain and in prion diseases
-
Chen SG, Teplow DB, Pachi P, Teller JK, Gambetti P and Autilio-Gambetti L. Truncated forms of the human prion protein in normal brain and in prion diseases. J Biol Chem 270: 19173-19180 (1995).
-
(1995)
J Biol Chem
, vol.270
, pp. 19173-19180
-
-
Chen, S.G.1
Teplow, D.B.2
Pachi, P.3
Teller, J.K.4
Gambetti, P.5
Autilio-Gambetti, L.6
-
21
-
-
0027483615
-
Neurotoxicity of a prion protein fragment
-
Forloni G, Angeretti N, Chiesa R, Monzani E, Salmona M, Bugiani O, et al. Neurotoxicity of a prion protein fragment. Nature 362: 543-546 (1993).
-
(1993)
Nature
, vol.362
, pp. 543-546
-
-
Forloni, G.1
Angeretti, N.2
Chiesa, R.3
Monzani, E.4
Salmona, M.5
Bugiani, O.6
-
22
-
-
0026721943
-
β-amyloid precursor protein cleavage by a membranebound protease
-
Sisodia SS. β-amyloid precursor protein cleavage by a membranebound protease. Proc Natl Acad Sci USA 89: 6075-6079 (1992).
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6075-6079
-
-
Sisodia, S.S.1
-
23
-
-
0027484116
-
The Alzheimer β-amyloid protein precursor/protein nexin II is cleaved by secretase in a trans golgi secretory compartment in human neuroglioma cells
-
Kuentzel SL, Ali SM, Altman RA, Greenberg BD and Raub TJ. The Alzheimer β-amyloid protein precursor/protein nexin II is cleaved by secretase in a trans golgi secretory compartment in human neuroglioma cells. Biochem J 295: 367-378 (1993).
-
(1993)
Biochem J
, vol.295
, pp. 367-378
-
-
Kuentzel, S.L.1
Ali, S.M.2
Altman, R.A.3
Greenberg, B.D.4
Raub, T.J.5
-
24
-
-
13444288081
-
Novel α-secretase cleavage of Alzheimer's amyloid β precursor protein in the endoplasmic reticulum of COS7 cells
-
Shin RW, Saido TC, Maeda M and Kitamoto T. Novel α-secretase cleavage of Alzheimer's amyloid β precursor protein in the endoplasmic reticulum of COS7 cells. Neurosci Lett 376: 14-19 (2005).
-
(2005)
Neurosci Lett
, vol.376
, pp. 14-19
-
-
Shin, R.W.1
Saido, T.C.2
Maeda, M.3
Kitamoto, T.4
-
25
-
-
0024395366
-
Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts
-
Saitoh T, Sundsmo M, Roch JM, Kimura N, Cole G, Schubert D, et al. Secreted form of amyloid β protein precursor is involved in the growth regulation of fibroblasts. Cell 58: 615-622 (1989).
-
(1989)
Cell
, vol.58
, pp. 615-622
-
-
Saitoh, T.1
Sundsmo, M.2
Roch, J.M.3
Kimura, N.4
Cole, G.5
Schubert, D.6
-
26
-
-
0032539666
-
From differentiation to proliferation: The secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells
-
Pietrzik CU, Hoffmann J, Stöber K, Chen CY, Bauer C, Otero DA, et al. From differentiation to proliferation: the secretory amyloid precursor protein as a local mediator of growth in thyroid epithelial cells. Proc Natl Acad Sci USA 95: 1770-1775 (1998).
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1770-1775
-
-
Pietrzik, C.U.1
Hoffmann, J.2
Stöber, K.3
Chen, C.Y.4
Bauer, C.5
Otero, D.A.6
-
27
-
-
0141483463
-
sAPP as a regulator of dendritic motility and melanin release in epidermal melanocytes and melanoma cells
-
Quast T, Wehner S, Kirfel G, Jaeger K, De Luca M and Herzog V. sAPP as a regulator of dendritic motility and melanin release in epidermal melanocytes and melanoma cells. FASEB J 17: 1739-1741 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 1739-1741
-
-
Quast, T.1
Wehner, S.2
Kirfel, G.3
Jaeger, K.4
De Luca, M.5
Herzog, V.6
-
28
-
-
2542519087
-
Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone
-
Caillé I, Allinquant B, Dupont E, Bouillot C, Langer A, Müller U, et al. Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone. Development 131: 2173-2181 (2004).
-
(2004)
Development
, vol.131
, pp. 2173-2181
-
-
Caillé, I.1
Allinquant, B.2
Dupont, E.3
Bouillot, C.4
Langer, A.5
Müller, U.6
-
29
-
-
0027478347
-
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein
-
Mattson MP, Cheng B, Culwell AR, Esch FS, Lieberburg I and Rydel RE. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein. Neuron 10: 243-254 (1993).
-
(1993)
Neuron
, vol.10
, pp. 243-254
-
-
Mattson, M.P.1
Cheng, B.2
Culwell, A.R.3
Esch, F.S.4
Lieberburg, I.5
Rydel, R.E.6
-
30
-
-
0030068094
-
Activation of K+ channels and suppression of neuronal activity by secreted β-amyloid precursor protein
-
Furukawa K, Barger SW, Blalock EM and Mattson MP. Activation of K+ channels and suppression of neuronal activity by secreted β-amyloid precursor protein. Nature 379: 74-78 (1996).
-
(1996)
Nature
, vol.379
, pp. 74-78
-
-
Furukawa, K.1
Barger, S.W.2
Blalock, E.M.3
Mattson, M.P.4
-
31
-
-
0031905682
-
Secreted amyloid precursor protein α selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: Involvement of cyclic AMP
-
Furukawa K and Mattson MP. Secreted amyloid precursor protein α selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic AMP. Neuroscience 83: 429-438 (1998).
-
(1998)
Neuroscience
, vol.83
, pp. 429-438
-
-
Furukawa, K.1
Mattson, M.P.2
-
32
-
-
0029917041
-
Expression in brain of amyloid precursor protein mutated in the α-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice
-
Moechars D, Lorent K, De Strooper B, Dewachter I and Van Leuven F. Expression in brain of amyloid precursor protein mutated in the α-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice. EMBO J 15: 1265-1274 (1996).
-
(1996)
EMBO J
, vol.15
, pp. 1265-1274
-
-
Moechars, D.1
Lorent, K.2
De Strooper, B.3
Dewachter, I.4
Van Leuven, F.5
-
33
-
-
0029841562
-
Increased activity-regulating and neuroprotective efficacy of α-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain
-
Furukawa K, Sopher BL, Rydel RE, Begley JG, Pham DG, Martin GM, et al. Increased activity-regulating and neuroprotective efficacy of α-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. J. Neurochem 67: 1882-1896 (1996).
-
(1996)
J. Neurochem
, vol.67
, pp. 1882-1896
-
-
Furukawa, K.1
Sopher, B.L.2
Rydel, R.E.3
Begley, J.G.4
Pham, D.G.5
Martin, G.M.6
-
34
-
-
0032514633
-
Memory-enhancing effects of secreted forms of the β-amyloid precursor protein in normal and amnestic mice
-
Meziane H, Dodart JC, Mathis C, Little S, Clemens, Paul SM, et al. Memory-enhancing effects of secreted forms of the β-amyloid precursor protein in normal and amnestic mice. Proc Natl Acad Sci USA 95: 12683-12688 (1998).
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12683-12688
-
-
Meziane, H.1
Dodart, J.C.2
Mathis, C.3
Little, S.4
Clemens, P.S.M.5
-
35
-
-
0242442605
-
Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence proliferation
-
Hansel DE, Rahman A, Wehner S, Herzog V, Yeo CJ and Maitra A. Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence proliferation. Cancer Res 63: 7032-7037 (2003).
-
(2003)
Cancer Res
, vol.63
, pp. 7032-7037
-
-
Hansel, D.E.1
Rahman, A.2
Wehner, S.3
Herzog, V.4
Yeo, C.J.5
Maitra, A.6
-
36
-
-
33745632662
-
Presenilin-dependent g-secretase-mediated control of p53-associated cell death in Alzheimer's disease
-
Alves da Costa C, Sunyach C, Pardossi-Piquard R, Sévalle J, Vincent B, Boyer N, et al. Presenilin-dependent g-secretase-mediated control of p53-associated cell death in Alzheimer's disease. J Neurosci 26: 6377-6385 (2006).
-
(2006)
J Neurosci
, vol.26
, pp. 6377-6385
-
-
Alves da Costa, C.1
Sunyach, C.2
Pardossi-Piquard, R.3
Sévalle, J.4
Vincent, B.5
Boyer, N.6
-
37
-
-
0347683432
-
Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels
-
Paitel E, Sunyach C, Alves da Costa C, Bourdon JC, Vincent B and Checler F. Primary cultured neurons devoid of cellular prion display lower responsiveness to staurosporine through the control of p53 at both transcriptional and post-transcriptional levels. J Biol Chem 279: 612-618 (2004).
-
(2004)
J Biol Chem
, vol.279
, pp. 612-618
-
-
Paitel, E.1
Sunyach, C.2
Alves da Costa, C.3
Bourdon, J.C.4
Vincent, B.5
Checler, F.6
-
38
-
-
33847299070
-
The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation
-
Sunyach C, Alfa Cissé M, Alves da Costa C, Vincent B and Checler F. The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation. J Biol Chem 282: 1956-1963 (2007).
-
(2007)
J Biol Chem
, vol.282
, pp. 1956-1963
-
-
Sunyach, C.1
Alfa Cissé, M.2
Alves da Costa, C.3
Vincent, B.4
Checler, F.5
-
39
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Büeler H, Fischer M, Lang Y, Bluethmann H, Lipp H, DeArmond S, et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 356: 577-582 (1992).
-
(1992)
Nature
, vol.356
, pp. 577-582
-
-
Büeler, H.1
Fischer, M.2
Lang, Y.3
Bluethmann, H.4
Lipp, H.5
DeArmond, S.6
-
40
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Büeler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, et al. Mice devoid of PrP are resistant to scrapie. Cell 73: 1339-1347 (1993).
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Büeler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.A.4
Autenried, P.5
Aguet, M.6
-
42
-
-
0037224740
-
The ADAMs family of metalloproteases: Multidomain proteins with multiple functions
-
Seals DF and Courtneidge SA. The ADAMs family of metalloproteases: multidomain proteins with multiple functions. Genes Dev 17: 7-30 (2003).
-
(2003)
Genes Dev
, vol.17
, pp. 7-30
-
-
Seals, D.F.1
Courtneidge, S.A.2
-
43
-
-
14444272986
-
Evidence that tumor necrosis factor α-converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor
-
Buxbaum JD, Liu KN, Luo Y, Slack JL, Stocking KL, Peschon JJ, et al. Evidence that tumor necrosis factor α-converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor. J Biol Chem 273: 27765-27767 (1998).
-
(1998)
J Biol Chem
, vol.273
, pp. 27765-27767
-
-
Buxbaum, J.D.1
Liu, K.N.2
Luo, Y.3
Slack, J.L.4
Stocking, K.L.5
Peschon, J.J.6
-
44
-
-
0035851151
-
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein
-
Vincent B, Paitel E, Saftig P, Frobert Y, Hartmann D, De Strooper B, et al. The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein. J Biol Chem 276: 37743-37746 (2001).
-
(2001)
J Biol Chem
, vol.276
, pp. 37743-37746
-
-
Vincent, B.1
Paitel, E.2
Saftig, P.3
Frobert, Y.4
Hartmann, D.5
De Strooper, B.6
-
45
-
-
0035424693
-
Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-α converting enzyme
-
Slack BE, Ma LK and Seah CC. Constitutive shedding of the amyloid precursor protein ectodomain is up-regulated by tumour necrosis factor-α converting enzyme. Biochem J 357: 787-794 (2001).
-
(2001)
Biochem J
, vol.357
, pp. 787-794
-
-
Slack, B.E.1
Ma, L.K.2
Seah, C.C.3
-
46
-
-
33745747556
-
Design and characterization of a novel cellular prion-derived quenched fluorimetric substrate of α-secretase
-
Alfa Cissé M, Gandreuil C, Hernandez JF, Martinez J, Checler F and Vincent B. Design and characterization of a novel cellular prion-derived quenched fluorimetric substrate of α-secretase. Biochem Biophys Res Commun 347: 254-260 (2006).
-
(2006)
Biochem Biophys Res Commun
, vol.347
, pp. 254-260
-
-
Alfa Cissé, M.1
Gandreuil, C.2
Hernandez, J.F.3
Martinez, J.4
Checler, F.5
Vincent, B.6
-
47
-
-
34247115682
-
-
Alfa Cissé M, Sunyach C, Slack BE, Fisher A, Vincent B and Checler F. M1 and M3 muscarinic receptors control physiological processing of cellular prion by modulating ADAM17 phosphorylation and acticity. J Neurosci 27: 4083-4092 (2007).
-
Alfa Cissé M, Sunyach C, Slack BE, Fisher A, Vincent B and Checler F. M1 and M3 muscarinic receptors control physiological processing of cellular prion by modulating ADAM17 phosphorylation and acticity. J Neurosci 27: 4083-4092 (2007).
-
-
-
-
48
-
-
0033616716
-
Constitutive and regulated α-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease
-
Lammich S, Kojro E, Postina R, Gilbert S, Pfeiffer R, Jasionowski M, et al. Constitutive and regulated α-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease. Proc Natl Acad Sci USA 96: 3922-3927 (1999).
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3922-3927
-
-
Lammich, S.1
Kojro, E.2
Postina, R.3
Gilbert, S.4
Pfeiffer, R.5
Jasionowski, M.6
-
49
-
-
0035089318
-
Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: Involvement of the pro-hormone convertase 7 and the disintegrin ADAM10
-
Lopez-Perez E, Zhang Y, Frank SLJ, Creemers J, Seidah N and Checler F. Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin ADAM10. J Neurochem 76: 1532-1539 (2001).
-
(2001)
J Neurochem
, vol.76
, pp. 1532-1539
-
-
Lopez-Perez, E.1
Zhang, Y.2
Frank, S.L.J.3
Creemers, J.4
Seidah, N.5
Checler, F.6
-
50
-
-
0036796421
-
The disintegrin/metalloprotease ADAM10 is essential for notch signalling but not for α-secretase activity in fibroblasts
-
Hartmann D, De Strooper B, Serneels L, Craesserts K, Herreman A, Annaert W, et al. The disintegrin/metalloprotease ADAM10 is essential for notch signalling but not for α-secretase activity in fibroblasts. Hum Mol Genet 11: 2615-2624 (2002).
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2615-2624
-
-
Hartmann, D.1
De Strooper, B.2
Serneels, L.3
Craesserts, K.4
Herreman, A.5
Annaert, W.6
-
51
-
-
28844433559
-
The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity
-
Alfa Cissé M, Sunyach C, Lefranc-Jullien S, Postina R, Vincent B and Checler F. The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity. J Biol Chem 280: 40624-40631 (2005).
-
(2005)
J Biol Chem
, vol.280
, pp. 40624-40631
-
-
Alfa Cissé, M.1
Sunyach, C.2
Lefranc-Jullien, S.3
Postina, R.4
Vincent, B.5
Checler, F.6
-
52
-
-
85047690140
-
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model
-
Postina R, Schroeder A, Dewachter I, Bohl J, Schmitt U, Kojro E, et al. A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model. J Clin Invest 113: 1456-1464 (2004).
-
(2004)
J Clin Invest
, vol.113
, pp. 1456-1464
-
-
Postina, R.1
Schroeder, A.2
Dewachter, I.3
Bohl, J.4
Schmitt, U.5
Kojro, E.6
-
53
-
-
27744581333
-
The N-terminal cleavage of cellular prion protein in the human brain
-
Laffont-Proust I, Faucheux BA, Hässig R, Sazdovitch V, Simon S, Grassi J, et al. The N-terminal cleavage of cellular prion protein in the human brain. FEBS Lett 579: 6333-6337 (2005).
-
(2005)
FEBS Lett
, vol.579
, pp. 6333-6337
-
-
Laffont-Proust, I.1
Faucheux, B.A.2
Hässig, R.3
Sazdovitch, V.4
Simon, S.5
Grassi, J.6
-
54
-
-
0033569653
-
Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein
-
Koike H, Tomioka S, Sorimachi H, Saido TC, Maruyama K, Okuyama A, et al. Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein. Biochem J 343: 371-375 (1999).
-
(1999)
Biochem J
, vol.343
, pp. 371-375
-
-
Koike, H.1
Tomioka, S.2
Sorimachi, H.3
Saido, T.C.4
Maruyama, K.5
Okuyama, A.6
-
56
-
-
0037474447
-
Putative function of ADAM9, ADAM10, and ADAM17 as APP α-secretase
-
Asai M, Hattori C, Szabo B, Sasagawa N, Maruyama K, Tanuma SI, et al. Putative function of ADAM9, ADAM10, and ADAM17 as APP α-secretase. Biochem Biophys Res Commun 301: 231-235 (2003).
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 231-235
-
-
Asai, M.1
Hattori, C.2
Szabo, B.3
Sasagawa, N.4
Maruyama, K.5
Tanuma, S.I.6
-
57
-
-
0033525037
-
Metalloprotease-disintegrin MDC9: Intracellular maturation and catalytic activity
-
Roghani M, Becherer JD, Moss ML, Atherton RE, Erdjument-Bromage H, Arribas J, et al. Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. J Biol Chem 274: 3531-3540 (1999).
-
(1999)
J Biol Chem
, vol.274
, pp. 3531-3540
-
-
Roghani, M.1
Becherer, J.D.2
Moss, M.L.3
Atherton, R.E.4
Erdjument-Bromage, H.5
Arribas, J.6
-
58
-
-
33751409639
-
ADAM19 is tightly associated with constitutive Alzheimer's disease APP α-secretase in A172 cells
-
Tanabe C, Hotoda N, Sasagawa N, Sehara-Fujisawa A, Maruyama K and Ishiura S. ADAM19 is tightly associated with constitutive Alzheimer's disease APP α-secretase in A172 cells. Biochem Biophys Res Commun 352: 111-117 (2007).
-
(2007)
Biochem Biophys Res Commun
, vol.352
, pp. 111-117
-
-
Tanabe, C.1
Hotoda, N.2
Sasagawa, N.3
Sehara-Fujisawa, A.4
Maruyama, K.5
Ishiura, S.6
-
59
-
-
33846528583
-
PKC signaling deficits: A mechanistic hypothesis for the origins of Alzheimer's disease
-
Alkon DL, Sun MK and Nelson TJ. PKC signaling deficits: a mechanistic hypothesis for the origins of Alzheimer's disease. Trends in Pharmacol Sci 28: 51-60 (2006).
-
(2006)
Trends in Pharmacol Sci
, vol.28
, pp. 51-60
-
-
Alkon, D.L.1
Sun, M.K.2
Nelson, T.J.3
-
60
-
-
0025296205
-
Processing of Alzheimer β/A4 amyloid precursor protein: Modulation by agents that regulate protein phosphorylation
-
Buxbaum JD, Gandy SE, Cicchetti P, Ehrlich ME, Czernik AJ, Fracasso RP, et al. Processing of Alzheimer β/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation. Proc Natl Acad Sci USA 87: 6003-6006 (1990).
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6003-6006
-
-
Buxbaum, J.D.1
Gandy, S.E.2
Cicchetti, P.3
Ehrlich, M.E.4
Czernik, A.J.5
Fracasso, R.P.6
-
61
-
-
0034634655
-
Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons
-
Vincent B, Paitel E, Frobert Y, Lehmann S, Grassi J and Checler F. Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons. J Biol Chem 275: 35612-35616 (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 35612-35616
-
-
Vincent, B.1
Paitel, E.2
Frobert, Y.3
Lehmann, S.4
Grassi, J.5
Checler, F.6
-
62
-
-
0027435535
-
Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide
-
Buxbaum JD, Koo EH and Greengard P. Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide. Proc Natl Acad Sci USA 90: 9195-9198 (1993).
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9195-9198
-
-
Buxbaum, J.D.1
Koo, E.H.2
Greengard, P.3
-
63
-
-
0026476297
-
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch RM, Slack BE, Wurtman RJ and Growdon JH. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 258: 304-307 (1992).
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
Growdon, J.H.4
-
64
-
-
0026448114
-
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer β/A4 amyloid protein precursor
-
Buxbaum JD, Oishi M, Chen HI, Pinkas-Kramarski R, Jaffe EA, Gandy SE, et al. Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer β/A4 amyloid protein precursor. Proc Natl Acad Sci USA 89: 10075-10078 (1992).
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10075-10078
-
-
Buxbaum, J.D.1
Oishi, M.2
Chen, H.I.3
Pinkas-Kramarski, R.4
Jaffe, E.A.5
Gandy, S.E.6
-
65
-
-
33645799439
-
-
Kojro E, Postina R, Buro C, Meiringer C, Gehrig-Burger K and Fahrenholz F. The neuropeptide PACAP promotes the α-secretase pathway for processing the Alzheimer amyloid precursor protein. FASEB J 20: 512-514 (2006).
-
Kojro E, Postina R, Buro C, Meiringer C, Gehrig-Burger K and Fahrenholz F. The neuropeptide PACAP promotes the α-secretase pathway for processing the Alzheimer amyloid precursor protein. FASEB J 20: 512-514 (2006).
-
-
-
-
66
-
-
0027487188
-
Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase Cα
-
Slack BE, Nitsch RM, Livneh E, Kunz GM, Breu J, Eldar H, et al. Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase Cα. J Biol Chem 268: 21097-21101 (1993).
-
(1993)
J Biol Chem
, vol.268
, pp. 21097-21101
-
-
Slack, B.E.1
Nitsch, R.M.2
Livneh, E.3
Kunz, G.M.4
Breu, J.5
Eldar, H.6
-
67
-
-
0028965767
-
Conventional protein kinase C (PKC)-αand novel PKCε, but not δ, increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 cells
-
Kinouchi T, Sorimachi H, Maruyama K, Mizuno K, Ohno S, Ishiura S, et al. Conventional protein kinase C (PKC)-αand novel PKCε, but not δ, increase the secretion of an N-terminal fragment of Alzheimer's disease amyloid precursor protein from PKC cDNA transfected 3Y1 cells. FEBS Lett 364: 203-206 (1995).
-
(1995)
FEBS Lett
, vol.364
, pp. 203-206
-
-
Kinouchi, T.1
Sorimachi, H.2
Maruyama, K.3
Mizuno, K.4
Ohno, S.5
Ishiura, S.6
-
68
-
-
0035319002
-
Protein kinase Cα and β1 are regulators of α-secretase secretory proteolytic processing of amyloid precursor protein in vivo
-
Roßner S, Mendla K, Schliebs R and Bigl V. Protein kinase Cα and β1 are regulators of α-secretase secretory proteolytic processing of amyloid precursor protein in vivo. Eur J Neurosci 13: 1644-1648 (2001).
-
(2001)
Eur J Neurosci
, vol.13
, pp. 1644-1648
-
-
Roßner, S.1
Mendla, K.2
Schliebs, R.3
Bigl, V.4
-
69
-
-
0029863203
-
Metabolism of Alzheimer β-amyloid precursor protein : Regulation by protein kinase A in intact cells and in a cell-free system
-
Xu H, Sweeney D, Greengard P and Gandy SE. Metabolism of Alzheimer β-amyloid precursor protein : regulation by protein kinase A in intact cells and in a cell-free system. Proc Natl Acad Sci USA 93: 4081-4084 (1996).
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4081-4084
-
-
Xu, H.1
Sweeney, D.2
Greengard, P.3
Gandy, S.E.4
-
70
-
-
0029805807
-
Protein kinase A phosphorylation of the proteasome: A contribution to the α-secretase pathway in human cells
-
Marambaud P, Wilk S and Checler F. Protein kinase A phosphorylation of the proteasome: a contribution to the α-secretase pathway in human cells. J Neurochem 67: 2616-2619 (1996).
-
(1996)
J Neurochem
, vol.67
, pp. 2616-2619
-
-
Marambaud, P.1
Wilk, S.2
Checler, F.3
-
71
-
-
0030035594
-
Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated cleavage of amyloid precursor protein
-
Efthimiopoulos S, Punj S, Manolopoulos V, Pangalos M, Wang GP, Refolo LM, et al. Intracellular cyclic AMP inhibits constitutive and phorbol ester-stimulated cleavage of amyloid precursor protein. J Neurochem 67: 872-875 (1996).
-
(1996)
J Neurochem
, vol.67
, pp. 872-875
-
-
Efthimiopoulos, S.1
Punj, S.2
Manolopoulos, V.3
Pangalos, M.4
Wang, G.P.5
Refolo, L.M.6
-
72
-
-
0033014431
-
Effects of protein kinase A inhibitors on the production of Aβ40 and Aβ42 by human cells expressing normal and Alzheimer's disease-linked mutated βAPP and presenilin 1
-
Marambaud P, Ancolio K, Alves da Costa C and Checler F. Effects of protein kinase A inhibitors on the production of Aβ40 and Aβ42 by human cells expressing normal and Alzheimer's disease-linked mutated βAPP and presenilin 1. Brit J Pharmacol 126: 1186-1190 (1999).
-
(1999)
Brit J Pharmacol
, vol.126
, pp. 1186-1190
-
-
Marambaud, P.1
Ancolio, K.2
Alves da Costa, C.3
Checler, F.4
-
73
-
-
0028295848
-
Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein
-
Suzuki T, Oishi M, Marshak DR, Czernik AJ, Nairn AC and Greengard P. Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. EMBO J 13: 1114-1122 (1994).
-
(1994)
EMBO J
, vol.13
, pp. 1114-1122
-
-
Suzuki, T.1
Oishi, M.2
Marshak, D.R.3
Czernik, A.J.4
Nairn, A.C.5
Greengard, P.6
-
74
-
-
0031453010
-
Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway
-
Mills J, Charest DL, Lam F, Beyreuther K, Ida N, Pelech SL and Reiner PB. Regulation of amyloid precursor protein catabolism involves the mitogen-activated protein kinase signal transduction pathway. J Neurosci 17: 9415-9422 (1997).
-
(1997)
J Neurosci
, vol.17
, pp. 9415-9422
-
-
Mills, J.1
Charest, D.L.2
Lam, F.3
Beyreuther, K.4
Ida, N.5
Pelech, S.L.6
Reiner, P.B.7
-
75
-
-
0031952526
-
Regulation of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade
-
Desdouits-Magnen J, Desdouits F, Takeda S., Syu LJ, Saltiel AR, Buxbaum JD, et al. Regulation of Alzheimer amyloid precursor protein by the mitogen-activated protein kinase cascade. J Neurochem 70: 524-530 (1998).
-
(1998)
J Neurochem
, vol.70
, pp. 524-530
-
-
Desdouits-Magnen, J.1
Desdouits, F.2
Takeda, S.3
Syu, L.J.4
Saltiel, A.R.5
Buxbaum, J.D.6
-
76
-
-
0032708232
-
The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein
-
Petanceska SS and Gandy SE. The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein. J Neurochem 73: 2316-2320 (1999).
-
(1999)
J Neurochem
, vol.73
, pp. 2316-2320
-
-
Petanceska, S.S.1
Gandy, S.E.2
-
77
-
-
0033588068
-
Regulated secretion of amyloid precursor protein by TrkA receptor stimulation in rat pheochromocytoma-12 cells is mitogen activated protein kinase sensitive
-
Roßner S, Ueberham U, Schliebs R, Perez-Polo JR and Bigl V. Regulated secretion of amyloid precursor protein by TrkA receptor stimulation in rat pheochromocytoma-12 cells is mitogen activated protein kinase sensitive. Neurosci Lett 271: 97-100 (1999).
-
(1999)
Neurosci Lett
, vol.271
, pp. 97-100
-
-
Roßner, S.1
Ueberham, U.2
Schliebs, R.3
Perez-Polo, J.R.4
Bigl, V.5
-
78
-
-
0035879075
-
Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-jun terminal kinase
-
Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, et al. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-jun terminal kinase. J Neurosci 21: 4987-4995 (2001).
-
(2001)
J Neurosci
, vol.21
, pp. 4987-4995
-
-
Mudher, A.1
Chapman, S.2
Richardson, J.3
Asuni, A.4
Gibb, G.5
Pollard, C.6
-
79
-
-
0038187674
-
GSK-3α regulates production of Alzheimer's disease amyloid-β peptides
-
Phiel CJ, Wilson CA, Lee VMY and Klein PS. GSK-3α regulates production of Alzheimer's disease amyloid-β peptides. Nature 423: 435-439 (2003).
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.Y.3
Klein, P.S.4
-
80
-
-
0038387872
-
Crosstalk between Rap1 and Rac regulates secretion of sAPPα
-
Maillet M, Robert SJ, Cacquevel M, Gastineau M, Vivien D, Bertoglio J, et al. Crosstalk between Rap1 and Rac regulates secretion of sAPPα. Nature Cell Biol 5: 633-639 (2003).
-
(2003)
Nature Cell Biol
, vol.5
, pp. 633-639
-
-
Maillet, M.1
Robert, S.J.2
Cacquevel, M.3
Gastineau, M.4
Vivien, D.5
Bertoglio, J.6
-
81
-
-
0038439081
-
Regulation of amyloid precursor protein expression and secretion via activation of ERK1/2 by hepatocyte growth factor in HEK293 cells transfected with APP751
-
Liu F, Su Y, Li B and Ni B. Regulation of amyloid precursor protein expression and secretion via activation of ERK1/2 by hepatocyte growth factor in HEK293 cells transfected with APP751. Exp Cell Res 287: 387-396 (2003).
-
(2003)
Exp Cell Res
, vol.287
, pp. 387-396
-
-
Liu, F.1
Su, Y.2
Li, B.3
Ni, B.4
-
82
-
-
15744397372
-
Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. Plos
-
Pedrini S, Carter TL, Prendergast G, Petanceska S, Ehrlich ME and Gandy S. Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. Plos Medicine 2: 69-78 (2005).
-
(2005)
Medicine
, vol.2
, pp. 69-78
-
-
Pedrini, S.1
Carter, T.L.2
Prendergast, G.3
Petanceska, S.4
Ehrlich, M.E.5
Gandy, S.6
-
83
-
-
33745793612
-
Interleukin-1α stimulates nonamyloidogenic pathway by α-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase
-
Bandyopadhyay S, Hartley DM, Cahill CM, Lahiri DK, Chattopadhyay N and Rogers JT. Interleukin-1α stimulates nonamyloidogenic pathway by α-secretase (ADAM-10 and ADAM-17) cleavage of APP in human astrocytic cells involving p38 MAP kinase. J Neurosci Res 84: 106-118 (2006).
-
(2006)
J Neurosci Res
, vol.84
, pp. 106-118
-
-
Bandyopadhyay, S.1
Hartley, D.M.2
Cahill, C.M.3
Lahiri, D.K.4
Chattopadhyay, N.5
Rogers, J.T.6
-
84
-
-
0031946864
-
Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
-
Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, et al. Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides. Nature Med 4: 447-451 (1998).
-
(1998)
Nature Med
, vol.4
, pp. 447-451
-
-
Xu, H.1
Gouras, G.K.2
Greenfield, J.P.3
Vincent, B.4
Naslund, J.5
Mazzarelli, L.6
-
85
-
-
0033950794
-
Testosterone reduces neuronal secretion of Alzheimer's β-amyloid peptides
-
Gouras GK, Xu H, Gross RS, Greenfield JP, Hai B, Wang R, et al. Testosterone reduces neuronal secretion of Alzheimer's β-amyloid peptides. Proc Natl Acad Sci USA 97: 1202-1205 (2000).
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1202-1205
-
-
Gouras, G.K.1
Xu, H.2
Gross, R.S.3
Greenfield, J.P.4
Hai, B.5
Wang, R.6
-
86
-
-
0027330178
-
Phospholipase A2 activation influences the processing and secretion of the amyloid precursor protein
-
Emmerling MR, Moore CJ, Doyle PD, Carroll RT and Davis RE. Phospholipase A2 activation influences the processing and secretion of the amyloid precursor protein. Biochem Biophys Res Commun 197: 292-297 (1993).
-
(1993)
Biochem Biophys Res Commun
, vol.197
, pp. 292-297
-
-
Emmerling, M.R.1
Moore, C.J.2
Doyle, P.D.3
Carroll, R.T.4
Davis, R.E.5
-
87
-
-
21444459918
-
P2Y2 nucleotide receptors enhance α-secretase-dependent amyloid precursor protein processing
-
Camden JM, Schrader AM, Camden RE, Gonzalez FA, Erb L, Seye CI, et al. P2Y2 nucleotide receptors enhance α-secretase-dependent amyloid precursor protein processing. J Biol Chem 280: 18696-18702 (2005).
-
(2005)
J Biol Chem
, vol.280
, pp. 18696-18702
-
-
Camden, J.M.1
Schrader, A.M.2
Camden, R.E.3
Gonzalez, F.A.4
Erb, L.5
Seye, C.I.6
-
88
-
-
0028207004
-
Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner
-
Buxbaum JD, Ruefli AA, Parker CA, Cypess AM and Greengard P. Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner. Proc Natl Acad Sci USA 91: 4489-4493 (1994).
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4489-4493
-
-
Buxbaum, J.D.1
Ruefli, A.A.2
Parker, C.A.3
Cypess, A.M.4
Greengard, P.5
-
89
-
-
0033430087
-
Copper inhibits β-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion
-
Borchardt T, Camakaris J, Cappai R, Masters CL, Beyreuther K and Multhaup G. Copper inhibits β-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion. Biochem J 344: 461-467 (1999).
-
(1999)
Biochem J
, vol.344
, pp. 461-467
-
-
Borchardt, T.1
Camakaris, J.2
Cappai, R.3
Masters, C.L.4
Beyreuther, K.5
Multhaup, G.6
-
90
-
-
0029972129
-
Effescts of alkalizing agents on the processing of the β-amyloid precursor protein
-
Schrader-Fischer G and Paganetti PA. Effescts of alkalizing agents on the processing of the β-amyloid precursor protein. Brain Res 716: 91-100 (1996).
-
(1996)
Brain Res
, vol.716
, pp. 91-100
-
-
Schrader-Fischer, G.1
Paganetti, P.A.2
-
91
-
-
0037200076
-
Non-steroidal antiinflammatory drugs stimulate secretion of non-amyloidogenic precursor protein
-
Avramovich Y, Amit T and Youdim MBH. Non-steroidal antiinflammatory drugs stimulate secretion of non-amyloidogenic precursor protein. J Biol Chem 277: 31466-31473 (2002).
-
(2002)
J Biol Chem
, vol.277
, pp. 31466-31473
-
-
Avramovich, Y.1
Amit, T.2
Youdim, M.B.H.3
-
92
-
-
2942590470
-
Amyloid precursor protein metabolism is regulated toward alpha-secretase pathway by Ginkgo biloba extracts
-
Colciaghi F, Borroni B, Zimmermann M, Bellone C, Longhi A, Padovani A, et al. Amyloid precursor protein metabolism is regulated toward alpha-secretase pathway by Ginkgo biloba extracts. Neurobiol Dis 16: 454-460 (2004).
-
(2004)
Neurobiol Dis
, vol.16
, pp. 454-460
-
-
Colciaghi, F.1
Borroni, B.2
Zimmermann, M.3
Bellone, C.4
Longhi, A.5
Padovani, A.6
-
93
-
-
0038661168
-
Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3- gallate
-
Levites Y, Amit T, Mandel S and Youdim MB. Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3- gallate. FASEB J 17:952-954 (2003).
-
(2003)
FASEB J
, vol.17
, pp. 952-954
-
-
Levites, Y.1
Amit, T.2
Mandel, S.3
Youdim, M.B.4
-
94
-
-
17444414627
-
Cholinesterase inhibitors influence APP metabolism in Alzheimer diseases patients
-
Zimmermann M, Borroni B, Cattabeni F, Padovani A and Di Luca M. Cholinesterase inhibitors influence APP metabolism in Alzheimer diseases patients. Neurobiol Dis 19: 237-242 (2005).
-
(2005)
Neurobiol Dis
, vol.19
, pp. 237-242
-
-
Zimmermann, M.1
Borroni, B.2
Cattabeni, F.3
Padovani, A.4
Di Luca, M.5
-
95
-
-
33344458827
-
M1 receptors play a central role in modulating AD-like pathology in transgenic mice
-
Caccamo A, Oddo S, Billings LM, Green KN, Martinez-Coria H, Fisher A, et al. M1 receptors play a central role in modulating AD-like pathology in transgenic mice. Neuron 49: 671-682 (2006).
-
(2006)
Neuron
, vol.49
, pp. 671-682
-
-
Caccamo, A.1
Oddo, S.2
Billings, L.M.3
Green, K.N.4
Martinez-Coria, H.5
Fisher, A.6
-
96
-
-
33845631997
-
-
Wang H, Lu Y and Wang Z. Function of cardiac M3 receptors. Autonomic Autocoid Pharmacol 27: 1-11 (2007).
-
Wang H, Lu Y and Wang Z. Function of cardiac M3 receptors. Autonomic Autocoid Pharmacol 27: 1-11 (2007).
-
-
-
-
97
-
-
0032032493
-
Turnover of amyloid protein in mouse brain and acute reduction of its level by phorbol ester
-
Savage M, Trusko SP, Howland DS, Pinsker LR, Mistretta S, Reaume AG, et al. Turnover of amyloid protein in mouse brain and acute reduction of its level by phorbol ester. J Neurosci 18: 1743-1752 (1998).
-
(1998)
J Neurosci
, vol.18
, pp. 1743-1752
-
-
Savage, M.1
Trusko, S.P.2
Howland, D.S.3
Pinsker, L.R.4
Mistretta, S.5
Reaume, A.G.6
-
98
-
-
0037472674
-
New amide-bearing benzolactam-based protein kinase C modulators induce enhanced secretion of the amyloid precursor protein metabolite sAPPα
-
Kozikowski AP, Nowak I, Petukhov PA, Etcheberrigaray R, Mohamed A, Tan M, et al. New amide-bearing benzolactam-based protein kinase C modulators induce enhanced secretion of the amyloid precursor protein metabolite sAPPα. J Med Chem 46: 364-373 (2003).
-
(2003)
J Med Chem
, vol.46
, pp. 364-373
-
-
Kozikowski, A.P.1
Nowak, I.2
Petukhov, P.A.3
Etcheberrigaray, R.4
Mohamed, A.5
Tan, M.6
-
99
-
-
3342934646
-
Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice
-
Etcheberrigaray R, Tan M, Dewachter I, Kuipéri C, Van der Auwera I, Wera S, et al. Therapeutic effects of PKC activators in Alzheimer's disease transgenic mice. Proc Natl Acad Sci USA 101: 11141-11146 (2004).
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11141-11146
-
-
Etcheberrigaray, R.1
Tan, M.2
Dewachter, I.3
Kuipéri, C.4
Van der Auwera, I.5
Wera, S.6
-
100
-
-
0035826909
-
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM10
-
Kojro E, Gimpl G, Lammich S, März W and Fahrenholz F. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM10. Proc Natl Acad Sci USA 98: 5815-5820 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5815-5820
-
-
Kojro, E.1
Gimpl, G.2
Lammich, S.3
März, W.4
Fahrenholz, F.5
-
101
-
-
33745209915
-
ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate- induced α-secretase cleavage of amyloid precursor protein
-
Obregon DF, Rezai-Zadeh K, Bai Y, Sun N, Hou H, Ehrhart J, et al. ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate- induced α-secretase cleavage of amyloid precursor protein. J Biol Chem 281: 16419-16427 (2006).
-
(2006)
J Biol Chem
, vol.281
, pp. 16419-16427
-
-
Obregon, D.F.1
Rezai-Zadeh, K.2
Bai, Y.3
Sun, N.4
Hou, H.5
Ehrhart, J.6
-
102
-
-
33847171931
-
Synapse-associated protein-97 mediates a-secretase ADAM10 trafficking and promotes its activity
-
Marcello E, Gardoni F, Mauceri D, Romorini S, Jeromin A, Epis R, et al. Synapse-associated protein-97 mediates a-secretase ADAM10 trafficking and promotes its activity. J Neurosci 14: 1682-1691 (2007).
-
(2007)
J Neurosci
, vol.14
, pp. 1682-1691
-
-
Marcello, E.1
Gardoni, F.2
Mauceri, D.3
Romorini, S.4
Jeromin, A.5
Epis, R.6
-
103
-
-
0037716445
-
Tumor necrosis factor-α converting enzyme is processed by proprotein- convertases to its mature form which is degraded upon phorbol ester stimulation
-
Endres K, Anders A, Kojro E, Gilbert S, Fahrenholz F and Postina R. Tumor necrosis factor-α converting enzyme is processed by proprotein- convertases to its mature form which is degraded upon phorbol ester stimulation. Eur J Biochem 270: 2386-2393 (2003).
-
(2003)
Eur J Biochem
, vol.270
, pp. 2386-2393
-
-
Endres, K.1
Anders, A.2
Kojro, E.3
Gilbert, S.4
Fahrenholz, F.5
Postina, R.6
-
104
-
-
0035430436
-
Regulation of the α-secretase ADAM10 by its prodomain and proprotein convertases
-
Anders A, Gilbert S, Garten W, Postina R and Fahrenholz F. Regulation of the α-secretase ADAM10 by its prodomain and proprotein convertases. FASEB J 15: 1837-1839 (2001).
-
(2001)
FASEB J
, vol.15
, pp. 1837-1839
-
-
Anders, A.1
Gilbert, S.2
Garten, W.3
Postina, R.4
Fahrenholz, F.5
-
105
-
-
0029774746
-
APMA (4-aminophenylmercuric acetate) activation of stromelysin-1 involves protein interactions in addition to those with cysteine-75 in the propeptide
-
Galazka G, Windsor LJ, Birkedal-Hansen H and Engler JA. APMA (4-aminophenylmercuric acetate) activation of stromelysin-1 involves protein interactions in addition to those with cysteine-75 in the propeptide. Biochemistry 35: 11221-11227 (1996).
-
(1996)
Biochemistry
, vol.35
, pp. 11221-11227
-
-
Galazka, G.1
Windsor, L.J.2
Birkedal-Hansen, H.3
Engler, J.A.4
-
106
-
-
1642503211
-
Hyaluronan-oligosaccharide-induced transcription of metalloproteases
-
Fieber C, Baumann P, Vallon R, Termeer C, Simon JC, Hofmann M, et al. Hyaluronan-oligosaccharide-induced transcription of metalloproteases. J Cell Sci 117: 359-367 (2004).
-
(2004)
J Cell Sci
, vol.117
, pp. 359-367
-
-
Fieber, C.1
Baumann, P.2
Vallon, R.3
Termeer, C.4
Simon, J.C.5
Hofmann, M.6
-
107
-
-
0032983865
-
Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis
-
Moore RJ, Owens DM, Stamp G, Arnott C, Burke F, East N, et al. Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis. Nature Med 5: 828-831 (1999).
-
(1999)
Nature Med
, vol.5
, pp. 828-831
-
-
Moore, R.J.1
Owens, D.M.2
Stamp, G.3
Arnott, C.4
Burke, F.5
East, N.6
-
108
-
-
0027366136
-
A novel metalloprotease/disintegrin-like gene at 17q21.3 is somatically rearranged in two primary breast cancers
-
Emi M, Katagiri T, Harada Y, Saito H, Inazawa J, Ito I, et al. A novel metalloprotease/disintegrin-like gene at 17q21.3 is somatically rearranged in two primary breast cancers. Nature Genet 5: 151-157 (1993).
-
(1993)
Nature Genet
, vol.5
, pp. 151-157
-
-
Emi, M.1
Katagiri, T.2
Harada, Y.3
Saito, H.4
Inazawa, J.5
Ito, I.6
-
109
-
-
33845748084
-
Increase of disintegrin metalloprotease 10 (ADAM10) expression in oral squamous cell carcinoma
-
Ko SY, Lin SC, Wong YK, Liu CJ, Chang KW and Liu TY. Increase of disintegrin metalloprotease 10 (ADAM10) expression in oral squamous cell carcinoma. Cancer Lett 245: 33-43 (2007).
-
(2007)
Cancer Lett
, vol.245
, pp. 33-43
-
-
Ko, S.Y.1
Lin, S.C.2
Wong, Y.K.3
Liu, C.J.4
Chang, K.W.5
Liu, T.Y.6
-
110
-
-
34247236142
-
Posttranscriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors
-
Santiago-Josefat B, Esselens C, Bech-Serra JJ and Arribas J. Posttranscriptional up-regulation of ADAM17 upon epidermal growth factor receptor activation and in breast tumors. J Biol Chem 282: 8325-8331 (2007).
-
(2007)
J Biol Chem
, vol.282
, pp. 8325-8331
-
-
Santiago-Josefat, B.1
Esselens, C.2
Bech-Serra, J.J.3
Arribas, J.4
|