Effect of protein kinase A inhibitors on the production of Aβ40 and Aβ42 by human cells expressing normal and Alzheimer's disease-linked mutated βAPP and presenilin 1

British Journal of Pharmacology

Volumn 126, Issue 5, 1999, Pages 1186-1190

  Marambaud, P ^a   Ancolio, K ^a   Alves Da Costa, C ^a   Checler, F ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Alzheimer's disease; Amyloid peptides; APP ; H89; HEK293 cells; Mutant presenilins; Mutant APP; Neurons; PKI; Protein kinase A

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLOHEXIMIDE; DACTINOMYCIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PRESENILIN 1;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; EMBRYO; HUMAN; HUMAN CELL; NEOCORTEX; NERVE CELL; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION;

EID: 0033014431     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702406     Document Type: Article

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