Protein kinase Cα and β1 isoforms are regulators of α-secretory proteolytic processing of amyloid precursor protein in vivo

European Journal of Neuroscience

Volumn 13, Issue 8, 2001, Pages 1644-1648

  Rossner S ^a   Mendla, K ^a,b   Schliebs, R ^a   Bigl, V ^a  

^a Paul Flechsig Inst for Brain Res   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Alzheimer's disease; Amyloid precursor protein processing; Animal model; Guinea pig; Microencephalopathy; Neocortex; Protein kinase C isoforms; Translocation

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; METHYLAZOXYMETHANOL ACETATE; PHORBOL ESTER; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA1; PROTEIN SUBUNIT; REGULATOR PROTEIN; UNCLASSIFIED DRUG; ISOENZYME; PEPTIDE HYDROLASE; PHORBOL DIBUTYRATE; PROTEIN KINASE C BETA; PROTEIN SYNTHESIS INHIBITOR;

AMYLOIDOSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ENZYME REGULATION; GUINEA PIG; IMMUNOCYTOCHEMISTRY; NEWBORN; NONHUMAN; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; ANIMAL; CELL FRACTIONATION; CONGENITAL MALFORMATION; DRUG EFFECT; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; METABOLISM; NEOCORTEX; PHOSPHORYLATION; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; ENZYME ACTIVATION; GUINEA PIGS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; METHYLAZOXYMETHANOL ACETATE; NEOCORTEX; PEPTIDE HYDROLASES; PHORBOL 12,13-DIBUTYRATE; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN SYNTHESIS INHIBITORS; SUBCELLULAR FRACTIONS;

EID: 0035319002     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816x.2001.01525.x     Document Type: Article

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