P2Y2 nucleotide receptors enhance α-secretase-dependent amyloid precursor protein processing

Journal of Biological Chemistry

Volumn 280, Issue 19, 2005, Pages 18696-18702

  Camden, Jean M ^a   Schrader, Ann M ^a   Camden, Ryan E ^a   González, Fernando A ^b   Erb, Laurie ^a   Seye, Cheikh I ^a   Weisman, Gary A ^a  

^a University of Missouri   (United States)

^b UNIVERSITY OF PUERTO RICO   (Puerto Rico)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMMONIA; BRAIN; CALCIUM; DISEASES; PATIENT MONITORING; SALTS;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN (APP); AMYLOIDS; CHELATORS;

PROTEINS;

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; CALCIUM ION; COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; G PROTEIN COUPLED RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PURINE P2Y2 RECEPTOR; RECEPTOR SUBTYPE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UO 126; URIDINE TRIPHOSPHATE; 1 OXODECYL ARGINYL VALYL LYSYL ARGININE CHLOROMETHYL KETONE; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 1-OXODECYL-ARGINYL-VALYL-LYSYL-ARGININE CHLOROMETHYL KETONE; ADAM PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; BISINDOLYLMALEIMIDE I; CALCIUM; CHELATING AGENT; DRUG DERIVATIVE; EGTAZIC ACID; FURIN; INDOLE DERIVATIVE; MALEIMIDE DERIVATIVE; METALLOPROTEINASE; NITRILE; PEPTIDE CHLOROMETHYL KETONE; PHORBOL ESTER; PROTEINASE; PURINE P2 RECEPTOR; SECRETASE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ALZHEIMER DISEASE; ARTICLE; ASTROCYTOMA CELL; CALCIUM MOBILIZATION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; NERVE CELL CULTURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; SENILE PLAQUE; BIOSYNTHESIS; CENTRAL NERVOUS SYSTEM; CHEMISTRY; DOSE RESPONSE; DOWN REGULATION; GENETIC TRANSFECTION; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

ADAM PROTEINS; AMINO ACID CHLOROMETHYL KETONES; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BLOTTING, WESTERN; BUTADIENES; CALCIUM; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM; CHELATING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; EGTAZIC ACID; ENDOPEPTIDASES; FURIN; HUMANS; INDOLES; MALEIMIDES; MAP KINASE SIGNALING SYSTEM; METALLOENDOPEPTIDASES; NITRILES; PHORBOL ESTERS; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PURINERGIC P2; RNA, SMALL INTERFERING; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TRANSFECTION; URIDINE TRIPHOSPHATE;

EID: 21444459918     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500219200     Document Type: Article

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