Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: Involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10

Journal of Neurochemistry

Volumn 76, Issue 5, 2001, Pages 1532-1539

  Lopez Perez, Elvira ^b   Zhang, Yue ^a   Frank, Stuart J ^c   Creemers, John ^d   Seidah, Nabil ^a   Checler, Frédéric ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c CENTER FOR HUMAN GENETICS   (Belgium)

^d CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

secretase; 1 PDX; Alzheimer's disease; Disintegrins; Prohormone convertases; sAPP

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; DISINTEGRIN; FURIN; METALLOPROTEINASE; PHORBOL ESTER; PROTEIN KINASE C;

ALZHEIMER DISEASE; ARTICLE; DNA CLEAVAGE; EFFECTOR CELL; ENZYME ACTIVITY; ENZYME REGULATION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECEPTOR BLOCKING;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; CELL LINE; ENDOPEPTIDASES; FURIN; HUMANS; KINETICS; PHORBOL 12,13-DIBUTYRATE; PROPROTEIN CONVERTASES; PROTEIN KINASE C; RECOMBINANT PROTEINS; SUBTILISINS; TETRADECANOYLPHORBOL ACETATE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035089318     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00180.x     Document Type: Article

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