M1 and M3 muscarinic receptors control physiological processing of cellular prion by modulating ADAM17 phosphorylation and activity

Journal of Neuroscience

Volumn 27, Issue 15, 2007, Pages 4083-4092

  Cissé, Moustapha Alfa ^a   Sunyach, Claire ^a   Slack, Barbara E ^b   Fisher, Abraham ^c   Vincent, Bruno ^a,d   Checler, Frédéric ^a,d  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^d CNRS   (France)

Author keywords

ADAM17; Cellular prion; HEK293; Muscarinic receptors; Phosphorylation; Primary cultured neurons; Regulated processing

Indexed keywords

ADAM 10 PROTEINASE; ADAM 9 PROTEINASE; AF 267B; CARBACHOL; DISINTEGRIN; METALLOPROTEINASE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M1 RECEPTOR AGONIST; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; PRION PROTEIN; PROTEIN KINASE C; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; ADAM PROTEIN; ENZYME INHIBITOR; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; CELL LINE; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; PRION;

ADAM PROTEINS; ANIMALS; CARBACHOL; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; MICE; PHOSPHORYLATION; PRIONS; RECEPTOR, MUSCARINIC M1; RECEPTOR, MUSCARINIC M3;

EID: 34247115682     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5293-06.2007     Document Type: Article

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