The phosphatidylinositol 3-kinase inhibitor wortmannin alters the metabolism of the Alzheimer's amyloid precursor protein

Journal of Neurochemistry

Volumn 73, Issue 6, 1999, Pages 2316-2320

  Petanceska, Suzana S ^a   Gandy, Sam ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

, , and secretase; Amyloid peptide; Soluble amyloid precursor protein ; Trans Golgi network; Vesicle trafficking

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; GOLGI COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; SENILE PLAQUE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANDROSTADIENES; ANIMALS; ASPARTIC ENDOPEPTIDASES; ENDOPEPTIDASES; ENZYME INHIBITORS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICE; NERVE TISSUE PROTEINS; NEUROBLASTOMA; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; SOLUBILITY; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032708232     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0732316.x     Document Type: Article

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