메뉴 건너뛰기




Volumn 39, Issue 1 SUPPL., 2008, Pages 97-113

Concepts in gene therapy for cartilage repair

Author keywords

Articular cartilage; Chondrocyte; Gene therapy; Growth factor; Mesenchymal stem cell

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CHORDIN; COMPLEMENTARY DNA; FAS ANTIGEN; FAS LIGAND; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; NITRIC OXIDE; NOGGIN; PARATHYROID HORMONE RELATED PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PLASMID DNA; PLATELET DERIVED GROWTH FACTOR; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; SCATTER FACTOR; SMAD6 PROTEIN; SMAD7 PROTEIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG; VIRUS VECTOR; WNT PROTEIN;

EID: 39749111452     PISSN: 00201383     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.injury.2008.01.034     Document Type: Article
Times cited : (132)

References (198)
  • 1
    • 0027721063 scopus 로고
    • Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages
    • Ahrens M., Ankenbauer T., Schroder D., et al. Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineages. DNA Cell Biol 12 10 (1993) 871-880
    • (1993) DNA Cell Biol , vol.12 , Issue.10 , pp. 871-880
    • Ahrens, M.1    Ankenbauer, T.2    Schroder, D.3
  • 2
    • 0033387072 scopus 로고    scopus 로고
    • Differential effects of IL-8, LIF (pro-inflammatory) and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on signaling pathways in human OA synovial fibroblasts
    • Alaaeddine N., Di Battista J.A., Pelletier J.P., et al. Differential effects of IL-8, LIF (pro-inflammatory) and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on signaling pathways in human OA synovial fibroblasts. Cytokine 11 12 (1999) 1020-1030
    • (1999) Cytokine , vol.11 , Issue.12 , pp. 1020-1030
    • Alaaeddine, N.1    Di Battista, J.A.2    Pelletier, J.P.3
  • 3
    • 0032906440 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor alpha-induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: distinct targeting in the signaling pathways
    • Alaaeddine N., Di Battista J.A., Pelletier J.P., et al. Inhibition of tumor necrosis factor alpha-induced prostaglandin E2 production by the antiinflammatory cytokines interleukin-4, interleukin-10, and interleukin-13 in osteoarthritic synovial fibroblasts: distinct targeting in the signaling pathways. Arthritis Rheum 42 4 (1999) 710-718
    • (1999) Arthritis Rheum , vol.42 , Issue.4 , pp. 710-718
    • Alaaeddine, N.1    Di Battista, J.A.2    Pelletier, J.P.3
  • 4
    • 0032102995 scopus 로고    scopus 로고
    • Adenovirusmediated transfer of viral IL-10 gene inhibitsmurine collageninduced arthritis
    • Apparailly F., Verwaerde C., Jacquet C., et al. Adenovirusmediated transfer of viral IL-10 gene inhibitsmurine collageninduced arthritis. J Immunol 160 11 (1998) 5213-5220
    • (1998) J Immunol , vol.160 , Issue.11 , pp. 5213-5220
    • Apparailly, F.1    Verwaerde, C.2    Jacquet, C.3
  • 5
    • 0036019191 scopus 로고    scopus 로고
    • Tetracycline-inducible interleukin- 10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis
    • Apparailly F., Millet V., Noel D., et al. Tetracycline-inducible interleukin- 10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis. Hum Gene Ther 13 10 (2002) 1179-1188
    • (2002) Hum Gene Ther , vol.13 , Issue.10 , pp. 1179-1188
    • Apparailly, F.1    Millet, V.2    Noel, D.3
  • 6
    • 0030761210 scopus 로고    scopus 로고
    • Adenovirus vector-mediated gene transduction to chondrocytes: in vitro evaluation of therapeutic efficacy of transforming growth factor-beta 1 and heat shock protein 70 gene transduction
    • Arai Y., Kubo T., Kobayashi K., et al. Adenovirus vector-mediated gene transduction to chondrocytes: in vitro evaluation of therapeutic efficacy of transforming growth factor-beta 1 and heat shock protein 70 gene transduction. J Rheumatol 24 9 (1997) 1787-1795
    • (1997) J Rheumatol , vol.24 , Issue.9 , pp. 1787-1795
    • Arai, Y.1    Kubo, T.2    Kobayashi, K.3
  • 7
    • 0034213942 scopus 로고    scopus 로고
    • Platelet-derived growth factor A modulates limb chondrogenesis both in vivo and in vitro
    • Ataliotis P. Platelet-derived growth factor A modulates limb chondrogenesis both in vivo and in vitro. Mech Dev 94 1-2 (2000) 13-24
    • (2000) Mech Dev , vol.94 , Issue.1-2 , pp. 13-24
    • Ataliotis, P.1
  • 8
    • 0030973263 scopus 로고    scopus 로고
    • Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee
    • Bakker A.C., Joosten L.A., Arntz O.J., et al. Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee. Arthritis Rheum 40 5 (1997) 893-900
    • (1997) Arthritis Rheum , vol.40 , Issue.5 , pp. 893-900
    • Bakker, A.C.1    Joosten, L.A.2    Arntz, O.J.3
  • 9
    • 1342327559 scopus 로고    scopus 로고
    • Regional gene therapy to enhance bone repair
    • Baltzer A.W., and Lieberman J.R. Regional gene therapy to enhance bone repair. Gene Ther 11 4 (2004) 344-350
    • (2004) Gene Ther , vol.11 , Issue.4 , pp. 344-350
    • Baltzer, A.W.1    Lieberman, J.R.2
  • 10
    • 0027435633 scopus 로고
    • Intraarticular expression of biologically active interleukin 1-receptor- antagonist protein by ex vivo gene transfer
    • Bandara G., Mueller G.M., Galea-Lauri J., et al. Intraarticular expression of biologically active interleukin 1-receptor- antagonist protein by ex vivo gene transfer. Proc Natl Acad Sci USA 90 22 (1993) 10764-10768
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.22 , pp. 10764-10768
    • Bandara, G.1    Mueller, G.M.2    Galea-Lauri, J.3
  • 11
    • 0028799826 scopus 로고
    • Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation
    • Baragi V.M., Renkiewicz R.R., Jordan H., et al. Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation. J Clin Invest 96 5 (1995) 2454-2460
    • (1995) J Clin Invest , vol.96 , Issue.5 , pp. 2454-2460
    • Baragi, V.M.1    Renkiewicz, R.R.2    Jordan, H.3
  • 12
    • 0030740745 scopus 로고    scopus 로고
    • Transplantation of adenovirally transduced allogeneic chondrocytes into articular cartilage defects in vivo
    • Baragi V.M., Renkiewicz R.R., Qiu L., et al. Transplantation of adenovirally transduced allogeneic chondrocytes into articular cartilage defects in vivo. Osteoarthritis Cartilage 5 4 (1997) 275-282
    • (1997) Osteoarthritis Cartilage , vol.5 , Issue.4 , pp. 275-282
    • Baragi, V.M.1    Renkiewicz, R.R.2    Qiu, L.3
  • 13
    • 33845713392 scopus 로고    scopus 로고
    • Evidence of calciumdependent pathway in the regulation of human beta1,3- glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis
    • Barre L., Venkatesan N., Magdalou J., et al. Evidence of calciumdependent pathway in the regulation of human beta1,3- glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis. Faseb J 20 10 (2006) 1692-1694
    • (2006) Faseb J , vol.20 , Issue.10 , pp. 1692-1694
    • Barre, L.1    Venkatesan, N.2    Magdalou, J.3
  • 14
    • 0035882056 scopus 로고    scopus 로고
    • Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation- dependent gene expression of matrix components
    • Barry F., Boynton R.E., Liu B., et al. Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation- dependent gene expression of matrix components. Exp Cell Res 268 2 (2001) 189-200
    • (2001) Exp Cell Res , vol.268 , Issue.2 , pp. 189-200
    • Barry, F.1    Boynton, R.E.2    Liu, B.3
  • 15
    • 7244220098 scopus 로고    scopus 로고
    • [Indications and implementation of recommendations of the working group «Tissue Regeneration and Tissue Substitutes» for autologous chondrocyte transplantation (ACT)]
    • Behrens P., Bosch U., Bruns J., et al. [Indications and implementation of recommendations of the working group «Tissue Regeneration and Tissue Substitutes» for autologous chondrocyte transplantation (ACT)]. Z Orthop Ihre Grenzgeb 142 5 (2004) 529-539
    • (2004) Z Orthop Ihre Grenzgeb , vol.142 , Issue.5 , pp. 529-539
    • Behrens, P.1    Bosch, U.2    Bruns, J.3
  • 16
    • 0028903034 scopus 로고
    • Differentiation-dependent effects of IL-1 and TGF-beta on human articular chondrocyte proliferation are related to inducible nitric oxide synthase expression
    • Blanco F.J., Geng Y., and Lotz M. Differentiation-dependent effects of IL-1 and TGF-beta on human articular chondrocyte proliferation are related to inducible nitric oxide synthase expression. J Immunol 154 8 (1995) 4018-4026
    • (1995) J Immunol , vol.154 , Issue.8 , pp. 4018-4026
    • Blanco, F.J.1    Geng, Y.2    Lotz, M.3
  • 17
    • 0033021062 scopus 로고    scopus 로고
    • Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration [see comments]
    • Bonadio J., Smiley E., Patil P., et al. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration [see comments]. Nat Med 5 7 (1999) 753-759
    • (1999) Nat Med , vol.5 , Issue.7 , pp. 753-759
    • Bonadio, J.1    Smiley, E.2    Patil, P.3
  • 18
    • 0034670057 scopus 로고    scopus 로고
    • Tissue engineering via local gene delivery: update and future prospects for enhancing the technology
    • Bonadio J. Tissue engineering via local gene delivery: update and future prospects for enhancing the technology. Adv Drug Deliv Rev 44 2-3 (2000) 185-194
    • (2000) Adv Drug Deliv Rev , vol.44 , Issue.2-3 , pp. 185-194
    • Bonadio, J.1
  • 19
    • 0031445020 scopus 로고    scopus 로고
    • Long-term results of rib perichondrial grafts for repair of cartilage defects in the human knee
    • Bouwmeester S.J., Beckers J.M., Kuijer R., et al. Long-term results of rib perichondrial grafts for repair of cartilage defects in the human knee. Int Orthop 21 5 (1997) 313-317
    • (1997) Int Orthop , vol.21 , Issue.5 , pp. 313-317
    • Bouwmeester, S.J.1    Beckers, J.M.2    Kuijer, R.3
  • 20
    • 0028031550 scopus 로고
    • Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
    • Brittberg M., Lindahl A., Nilsson A., et al. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331 14 (1994) 889-895
    • (1994) N Engl J Med , vol.331 , Issue.14 , pp. 889-895
    • Brittberg, M.1    Lindahl, A.2    Nilsson, A.3
  • 21
    • 0031661022 scopus 로고    scopus 로고
    • Articular cartilage: injuries and potential for healing
    • Buckwalter J.A. Articular cartilage: injuries and potential for healing. J Orthop Sports Phys Ther 28 4 (1998) 192-202
    • (1998) J Orthop Sports Phys Ther , vol.28 , Issue.4 , pp. 192-202
    • Buckwalter, J.A.1
  • 22
    • 0031856463 scopus 로고    scopus 로고
    • Articular cartilage repair and transplantation
    • Buckwalter J.A., and Mankin H.J. Articular cartilage repair and transplantation. Arthritis Rheum 41 8 (1998) 1331-1342
    • (1998) Arthritis Rheum , vol.41 , Issue.8 , pp. 1331-1342
    • Buckwalter, J.A.1    Mankin, H.J.2
  • 23
    • 0030842681 scopus 로고    scopus 로고
    • Principles of cartilage repair and regeneration
    • Caplan A.I., Elyaderani M., Mochizuki Y., et al. Principles of cartilage repair and regeneration. Clin Orthop 342 (1997) 254-269
    • (1997) Clin Orthop , Issue.342 , pp. 254-269
    • Caplan, A.I.1    Elyaderani, M.2    Mochizuki, Y.3
  • 24
    • 0033770819 scopus 로고    scopus 로고
    • Mesenchymal stem cells and gene therapy
    • Caplan A.I. Mesenchymal stem cells and gene therapy. Clin Orthop 379 Suppl (2000) S67-S70
    • (2000) Clin Orthop , vol.379 , Issue.SUPPL
    • Caplan, A.I.1
  • 25
    • 0034975453 scopus 로고    scopus 로고
    • Mesenchymal stem cells: building blocks for molecular medicine in the 21st century
    • Caplan A.I., and Bruder S.P. Mesenchymal stem cells: building blocks for molecular medicine in the 21st century. Trends Mol Med 7 6 (2001) 259-264
    • (2001) Trends Mol Med , vol.7 , Issue.6 , pp. 259-264
    • Caplan, A.I.1    Bruder, S.P.2
  • 26
    • 33746424373 scopus 로고    scopus 로고
    • Mesenchymal stem cells as trophic mediators
    • Caplan A.I., and Dennis J.E. Mesenchymal stem cells as trophic mediators. J Cell Biochem 98 5 (2006) 1076-1084
    • (2006) J Cell Biochem , vol.98 , Issue.5 , pp. 1076-1084
    • Caplan, A.I.1    Dennis, J.E.2
  • 27
    • 0034989585 scopus 로고    scopus 로고
    • Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of BMP-2
    • Carlberg A.L., Pucci B., Rallapalli R., et al. Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of BMP-2. Differentiation 67 4-5 (2001) 128-138
    • (2001) Differentiation , vol.67 , Issue.4-5 , pp. 128-138
    • Carlberg, A.L.1    Pucci, B.2    Rallapalli, R.3
  • 28
    • 33745745295 scopus 로고    scopus 로고
    • Insight: adult stem cells in cartilage regeneration and tissue engineering
    • Chen F.H., Rousche K.T., Tuan R.S., and Technology. Insight: adult stem cells in cartilage regeneration and tissue engineering. Nat Clin Pract Rheumatol 2 7 (2006) 373-382
    • (2006) Nat Clin Pract Rheumatol , vol.2 , Issue.7 , pp. 373-382
    • Chen, F.H.1    Rousche, K.T.2    Tuan, R.S.3    Technology4
  • 29
    • 0029559755 scopus 로고
    • Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor
    • Chernajovsky Y., Adams G., Podhajcer O.L., et al. Inhibition of transfer of collagen-induced arthritis into SCID mice by ex vivo infection of spleen cells with retroviruses expressing soluble tumor necrosis factor receptor. Gene Ther 2 10 (1995) 731-735
    • (1995) Gene Ther , vol.2 , Issue.10 , pp. 731-735
    • Chernajovsky, Y.1    Adams, G.2    Podhajcer, O.L.3
  • 30
    • 0034883069 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the at by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases
    • Conway J.G., Andrews R.C., Beaudet B., et al. Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the at by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases. J Pharmacol Exp Ther 298 3 (2001) 900-908
    • (2001) J Pharmacol Exp Ther , vol.298 , Issue.3 , pp. 900-908
    • Conway, J.G.1    Andrews, R.C.2    Beaudet, B.3
  • 31
    • 29744465669 scopus 로고    scopus 로고
    • Gene therapy for cartilage defects
    • Cucchiarini M., and Madry H. Gene therapy for cartilage defects. J Gene Med 7 12 (2005) 1495-1509
    • (2005) J Gene Med , vol.7 , Issue.12 , pp. 1495-1509
    • Cucchiarini, M.1    Madry, H.2
  • 32
    • 22644436809 scopus 로고    scopus 로고
    • Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2
    • Cucchiarini M., Madry H., Ma C., et al. Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2. Mol Ther 12 2 (2005) 229-238
    • (2005) Mol Ther , vol.12 , Issue.2 , pp. 229-238
    • Cucchiarini, M.1    Madry, H.2    Ma, C.3
  • 33
    • 33846208305 scopus 로고    scopus 로고
    • Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9
    • Cucchiarini M., Thurn T., WeimerA, et al. Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9. Arthritis Rheum 56 1 (2007) 158-167
    • (2007) Arthritis Rheum , vol.56 , Issue.1 , pp. 158-167
    • Cucchiarini, M.1    Thurn, T.2    WeimerA3
  • 34
    • 0038207145 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer to healing tendon-enhanced efficiency using a gelatin sponge
    • Dai Q., Manfield L., Wang Y., et al. Adenovirus-mediated gene transfer to healing tendon-enhanced efficiency using a gelatin sponge. J Orthop Res 21 (2003) 604-609
    • (2003) J Orthop Res , vol.21 , pp. 604-609
    • Dai, Q.1    Manfield, L.2    Wang, Y.3
  • 35
    • 0036729083 scopus 로고    scopus 로고
    • Interleukin 1 or tumor necrosis factor-alpha: which is the real target in rheumatoid arthritis?
    • Dayer J.M. Interleukin 1 or tumor necrosis factor-alpha: which is the real target in rheumatoid arthritis?. J Rheumatol Suppl 65 (2002) 10-15
    • (2002) J Rheumatol Suppl , vol.65 , pp. 10-15
    • Dayer, J.M.1
  • 36
    • 0033025281 scopus 로고    scopus 로고
    • Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures
    • Denker A.E., Haas A.R., Nicoll S.B., et al. Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures. Differentiation 64 2 (1999) 67-76
    • (1999) Differentiation , vol.64 , Issue.2 , pp. 67-76
    • Denker, A.E.1    Haas, A.R.2    Nicoll, S.B.3
  • 37
    • 0033510413 scopus 로고    scopus 로고
    • Stable transfection of human fetal chondrocytes with a type II procollagen minigene: expression of the mutant protein and alterations in the structure of the extracellular matrix in vitro
    • Dharmavaram R.M., Liu G., Tuan R.S., et al. Stable transfection of human fetal chondrocytes with a type II procollagen minigene: expression of the mutant protein and alterations in the structure of the extracellular matrix in vitro. Arthritis Rheum 42 7 (1999) 1433-1442
    • (1999) Arthritis Rheum , vol.42 , Issue.7 , pp. 1433-1442
    • Dharmavaram, R.M.1    Liu, G.2    Tuan, R.S.3
  • 38
    • 33744489059 scopus 로고    scopus 로고
    • Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix
    • Di Cesare P.E., Frenkel S.R., Carlson C.S., et al. Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix. J Orthop Res 24 5 (2006) 1118-1127
    • (2006) J Orthop Res , vol.24 , Issue.5 , pp. 1118-1127
    • Di Cesare, P.E.1    Frenkel, S.R.2    Carlson, C.S.3
  • 39
    • 0034787168 scopus 로고    scopus 로고
    • Impact of mechanical trauma on matrix and cells
    • D'Lima D.D., Hashimoto S., Chen P.C., et al. Impact of mechanical trauma on matrix and cells. Clin Orthop Relat Res 391 Suppl (2001) S90-S99
    • (2001) Clin Orthop Relat Res , vol.391 , Issue.SUPPL
    • D'Lima, D.D.1    Hashimoto, S.2    Chen, P.C.3
  • 40
    • 0034782952 scopus 로고    scopus 로고
    • Prevention of chondrocyte apoptosis
    • D'Lima D.D., Hashimoto S., Chen P.C., et al. Prevention of chondrocyte apoptosis. J Bone Joint Surg Am 83-A Suppl 2 Pt 1 (2001) 25-26
    • (2001) J Bone Joint Surg Am , vol.83 -A , Issue.SUPPL. 2 PART 1 , pp. 25-26
    • D'Lima, D.D.1    Hashimoto, S.2    Chen, P.C.3
  • 41
    • 0034771858 scopus 로고    scopus 로고
    • Cartilage injury induces chondrocyte apoptosis
    • D'Lima D.D., Hashimoto S., Chen P.C., et al. Cartilage injury induces chondrocyte apoptosis. J Bone Joint Surg Am 83-A Suppl 2 Pt 1 (2001) 19-21
    • (2001) J Bone Joint Surg Am , vol.83 -A , Issue.SUPPL. 2 PART 1 , pp. 19-21
    • D'Lima, D.D.1    Hashimoto, S.2    Chen, P.C.3
  • 42
    • 0032076306 scopus 로고    scopus 로고
    • Resurfacing of articular cartilage explants with genetically-modified human chondrocytes in vitro
    • Doherty P.J., Zhang H., Tremblay L., et al. Resurfacing of articular cartilage explants with genetically-modified human chondrocytes in vitro. Osteoarthritis Cartilage 6 3 (1998) 153-159
    • (1998) Osteoarthritis Cartilage , vol.6 , Issue.3 , pp. 153-159
    • Doherty, P.J.1    Zhang, H.2    Tremblay, L.3
  • 43
    • 33747595991 scopus 로고    scopus 로고
    • Selenium supplementation restores the antioxidative capacity and prevents cell damage in bonemarrow stromal cells in vitro
    • Ebert R., Ulmer M., Zeck S., et al. Selenium supplementation restores the antioxidative capacity and prevents cell damage in bonemarrow stromal cells in vitro. StemCells 24 5 (2006) 1226-1235
    • (2006) StemCells , vol.24 , Issue.5 , pp. 1226-1235
    • Ebert, R.1    Ulmer, M.2    Zeck, S.3
  • 44
    • 0034708608 scopus 로고    scopus 로고
    • Cbfa1 is a positive regulatory factor in chondrocyte maturation
    • Enomoto H., Enomoto-Iwamoto M., Iwamoto M., et al. Cbfa1 is a positive regulatory factor in chondrocyte maturation. J Biol Chem 275 12 (2000) 8695-8702
    • (2000) J Biol Chem , vol.275 , Issue.12 , pp. 8695-8702
    • Enomoto, H.1    Enomoto-Iwamoto, M.2    Iwamoto, M.3
  • 45
    • 0029806766 scopus 로고    scopus 로고
    • Differential effects of parathyroid hormone fragments on collagen gene expression in chondrocytes
    • Erdmann S., Muller W., Bahrami S., et al. Differential effects of parathyroid hormone fragments on collagen gene expression in chondrocytes. J Cell Biol 135 4 (1996) 1179-1191
    • (1996) J Cell Biol , vol.135 , Issue.4 , pp. 1179-1191
    • Erdmann, S.1    Muller, W.2    Bahrami, S.3
  • 46
    • 19144364120 scopus 로고    scopus 로고
    • Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis
    • Evans C.H., Robbins P.D., Ghivizzani S.C., et al. Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. Hum Gene Ther 7 10 (1996) 1261-1280
    • (1996) Hum Gene Ther , vol.7 , Issue.10 , pp. 1261-1280
    • Evans, C.H.1    Robbins, P.D.2    Ghivizzani, S.C.3
  • 47
    • 1342285045 scopus 로고    scopus 로고
    • Osteoarthritis gene therapy
    • Evans C.H., Gouze J.N., Gouze E., et al. Osteoarthritis gene therapy. Gene Ther 11 4 (2004) 379-389
    • (2004) Gene Ther , vol.11 , Issue.4 , pp. 379-389
    • Evans, C.H.1    Gouze, J.N.2    Gouze, E.3
  • 48
    • 9644259473 scopus 로고    scopus 로고
    • Genetically enhanced tissue engineering without cell culture or artificial scaffolds
    • Sandell A.J., and Grodzinsky L. (Eds), AAOS, Rosemont, ILL
    • Evans C.H., Pascher A., Betz O., et al. Genetically enhanced tissue engineering without cell culture or artificial scaffolds. In: Sandell A.J., and Grodzinsky L. (Eds). Orthopaedic Tissue Engineering (2004), AAOS, Rosemont, ILL 389-394
    • (2004) Orthopaedic Tissue Engineering , pp. 389-394
    • Evans, C.H.1    Pascher, A.2    Betz, O.3
  • 49
    • 20844432900 scopus 로고    scopus 로고
    • Gene transfer to human joints: progress toward a gene therapy of arthritis
    • Evans C.H., Robbins P.D., Ghivizzani S.C., et al. Gene transfer to human joints: progress toward a gene therapy of arthritis. Proc Natl Acad Sci USA 102 24 (2005) 8698-8703
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.24 , pp. 8698-8703
    • Evans, C.H.1    Robbins, P.D.2    Ghivizzani, S.C.3
  • 50
    • 33646474112 scopus 로고    scopus 로고
    • Gene therapeutic approaches-transfer in vivo
    • Evans C.H., Gouze E., Gouze J.N., et al. Gene therapeutic approaches-transfer in vivo. Adv Drug Deliv Rev 58 2 (2006) 243-258
    • (2006) Adv Drug Deliv Rev , vol.58 , Issue.2 , pp. 243-258
    • Evans, C.H.1    Gouze, E.2    Gouze, J.N.3
  • 51
    • 0037163093 scopus 로고    scopus 로고
    • Wnt-3A enhances bone morphogenetic protein-2-mediated chondrogenesis of murine C3H10T1/2 mesenchymal cells
    • Fischer L., Boland G., and Tuan R.S. Wnt-3A enhances bone morphogenetic protein-2-mediated chondrogenesis of murine C3H10T1/2 mesenchymal cells. J Biol Chem 277 34 (2002) 30870-30878
    • (2002) J Biol Chem , vol.277 , Issue.34 , pp. 30870-30878
    • Fischer, L.1    Boland, G.2    Tuan, R.S.3
  • 52
    • 0037389680 scopus 로고    scopus 로고
    • Anakinra, a recombinant human interleukin-1 receptor antagonist (rmetHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial
    • Fleischmann R.M., Schechtman J., Bennett R., et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (rmetHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial. Arthritis Rheum 48 4 (2003) 927-934
    • (2003) Arthritis Rheum , vol.48 , Issue.4 , pp. 927-934
    • Fleischmann, R.M.1    Schechtman, J.2    Bennett, R.3
  • 53
    • 0036207912 scopus 로고    scopus 로고
    • Insulin-like growth factor-I enhances cell-based repair of articular cartilage
    • Fortier L.A., Mohammed H.O., Lust G., et al. Insulin-like growth factor-I enhances cell-based repair of articular cartilage. J Bone Joint Surg Br 84 2 (2002) 276-288
    • (2002) J Bone Joint Surg Br , vol.84 , Issue.2 , pp. 276-288
    • Fortier, L.A.1    Mohammed, H.O.2    Lust, G.3
  • 54
    • 85047697321 scopus 로고    scopus 로고
    • Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene
    • Frisbie D.D., Ghivizzani S.C., Robbins P.D., et al. Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene. Gene Ther 9 1 (2002) 12-20
    • (2002) Gene Ther , vol.9 , Issue.1 , pp. 12-20
    • Frisbie, D.D.1    Ghivizzani, S.C.2    Robbins, P.D.3
  • 55
    • 0037261211 scopus 로고    scopus 로고
    • Combined effects of insulin-like growth factor-1 and transforming growth factorbeta1 on periostealmesenchymal cells during chondrogenesis in vitro
    • Fukumoto T., Sperling J.W., Sanyal A., et al. Combined effects of insulin-like growth factor-1 and transforming growth factorbeta1 on periostealmesenchymal cells during chondrogenesis in vitro. Osteoarthritis Cartilage 11 1 (2003) 55-64
    • (2003) Osteoarthritis Cartilage , vol.11 , Issue.1 , pp. 55-64
    • Fukumoto, T.1    Sperling, J.W.2    Sanyal, A.3
  • 56
    • 0034885826 scopus 로고    scopus 로고
    • Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer
    • Gelse K., Jiang Q.J., Aigner T., et al. Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer. Arthritis Rheum 44 8 (2001) 1943-1953
    • (2001) Arthritis Rheum , vol.44 , Issue.8 , pp. 1943-1953
    • Gelse, K.1    Jiang, Q.J.2    Aigner, T.3
  • 57
    • 0037331874 scopus 로고    scopus 로고
    • Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells
    • Gelse K., von der Mark K., Aigner T., et al. Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells. Arthritis Rheum 48 2 (2003) 430-441
    • (2003) Arthritis Rheum , vol.48 , Issue.2 , pp. 430-441
    • Gelse, K.1    von der Mark, K.2    Aigner, T.3
  • 58
    • 33646190866 scopus 로고    scopus 로고
    • Ex vivo gene therapy approaches to cartilage repair
    • Gelse K., and Schneider H. Ex vivo gene therapy approaches to cartilage repair. Adv Drug Deliv Rev 58 2 (2006) 259-284
    • (2006) Adv Drug Deliv Rev , vol.58 , Issue.2 , pp. 259-284
    • Gelse, K.1    Schneider, H.2
  • 59
    • 0031253812 scopus 로고    scopus 로고
    • Constitutive intraarticular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis
    • Ghivizzani S.C., Kang R., Georgescu H.I., et al. Constitutive intraarticular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis. J Immunol 159 7 (1997) 3604-3612
    • (1997) J Immunol , vol.159 , Issue.7 , pp. 3604-3612
    • Ghivizzani, S.C.1    Kang, R.2    Georgescu, H.I.3
  • 60
    • 0032515968 scopus 로고    scopus 로고
    • Direct adenovirusmediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects
    • Ghivizzani S.C., Lechman E.R., Kang R., et al. Direct adenovirusmediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects. Proc Natl Acad Sci USA 95 8 (1998) 4613-4618
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.8 , pp. 4613-4618
    • Ghivizzani, S.C.1    Lechman, E.R.2    Kang, R.3
  • 61
    • 0001762706 scopus 로고    scopus 로고
    • Direct gene delivery strategies for the treatment rheumatoid arthritis
    • Ghivizzani S.C., Oligino T.J., Glorioso J.C., et al. Direct gene delivery strategies for the treatment rheumatoid arthritis. Drug Discovery Today 6 5 (2001) 236-244
    • (2001) Drug Discovery Today , vol.6 , Issue.5 , pp. 236-244
    • Ghivizzani, S.C.1    Oligino, T.J.2    Glorioso, J.C.3
  • 62
    • 0036226899 scopus 로고    scopus 로고
    • In vivo gene delivery to synovium by lentiviral vectors
    • Gouze E., Pawliuk R., Pilapil C., et al. In vivo gene delivery to synovium by lentiviral vectors. Mol Ther 5 4 (2002) 397-404
    • (2002) Mol Ther , vol.5 , Issue.4 , pp. 397-404
    • Gouze, E.1    Pawliuk, R.2    Pilapil, C.3
  • 63
    • 0037689517 scopus 로고    scopus 로고
    • Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation
    • Gouze E., Pawliuk R., Gouze J.N., et al. Lentiviral-mediated gene delivery to synovium: potent intra-articular expression with amplification by inflammation. Mol Ther 7 4 (2003) 460-466
    • (2003) Mol Ther , vol.7 , Issue.4 , pp. 460-466
    • Gouze, E.1    Pawliuk, R.2    Gouze, J.N.3
  • 64
    • 2342505985 scopus 로고    scopus 로고
    • A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer
    • Gouze J.N., Gouze E., Palmer G.D., et al. A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer. Arthritis Res Ther 5 5 (2003) 301-309
    • (2003) Arthritis Res Ther , vol.5 , Issue.5 , pp. 301-309
    • Gouze, J.N.1    Gouze, E.2    Palmer, G.D.3
  • 65
    • 1342304425 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of glutamine: fructose-6-phosphate amidotransferase antagonizes the effects of interleukin-1beta on rat chondrocytes
    • Gouze J.N., Gouze E., Palmer G.D., et al. Adenovirus-mediated gene transfer of glutamine: fructose-6-phosphate amidotransferase antagonizes the effects of interleukin-1beta on rat chondrocytes. Osteoarthritis Cartilage 12 3 (2004) 217-224
    • (2004) Osteoarthritis Cartilage , vol.12 , Issue.3 , pp. 217-224
    • Gouze, J.N.1    Gouze, E.2    Palmer, G.D.3
  • 66
    • 16644397394 scopus 로고    scopus 로고
    • In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors
    • Gouze J.N., Stoddart M.J., Gouze E., et al. In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors. Methods Mol Med 100 (2004) 147-164
    • (2004) Methods Mol Med , vol.100 , pp. 147-164
    • Gouze, J.N.1    Stoddart, M.J.2    Gouze, E.3
  • 67
    • 0037739680 scopus 로고    scopus 로고
    • Stem cells as platforms for delivery of genes to enhance cartilage repair
    • Grande D.A., Mason J., Light E., et al. Stem cells as platforms for delivery of genes to enhance cartilage repair. J Bone Joint Surg Am 85-A Suppl 2 (2003) 111-116
    • (2003) J Bone Joint Surg Am , vol.85 -A , Issue.SUPPL. 2 , pp. 111-116
    • Grande, D.A.1    Mason, J.2    Light, E.3
  • 68
    • 0035046256 scopus 로고    scopus 로고
    • Effects of cartilagederived morphogenetic proteins and osteogenic protein-1 on osteochondrogenic differentiation of periosteum-derived cells
    • Gruber R., Mayer C., Bobacz K., et al. Effects of cartilagederived morphogenetic proteins and osteogenic protein-1 on osteochondrogenic differentiation of periosteum-derived cells. Endocrinology 142 5 (2001) 2087-2094
    • (2001) Endocrinology , vol.142 , Issue.5 , pp. 2087-2094
    • Gruber, R.1    Mayer, C.2    Bobacz, K.3
  • 69
    • 25444469346 scopus 로고    scopus 로고
    • Optimization of high-efficiency transfection of adult human mesenchymal stem cells in vitro
    • Haleem-Smith H., Derfoul A., Okafor C., et al. Optimization of high-efficiency transfection of adult human mesenchymal stem cells in vitro. Mol Biotechnol 30 1 (2005) 9-20
    • (2005) Mol Biotechnol , vol.30 , Issue.1 , pp. 9-20
    • Haleem-Smith, H.1    Derfoul, A.2    Okafor, C.3
  • 70
    • 0035047961 scopus 로고    scopus 로고
    • BMP-2 induction and TGF-beta 1 modulation of rat periosteal cell chondrogenesis
    • Hanada K., Solchaga L.A., Caplan A.I., et al. BMP-2 induction and TGF-beta 1 modulation of rat periosteal cell chondrogenesis. J Cell Biochem 81 2 (2001) 284-294
    • (2001) J Cell Biochem , vol.81 , Issue.2 , pp. 284-294
    • Hanada, K.1    Solchaga, L.A.2    Caplan, A.I.3
  • 71
    • 0038415816 scopus 로고    scopus 로고
    • Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience
    • Hangody L., and Fules P. Autologous osteochondral mosaicplasty for the treatment of full-thickness defects of weight-bearing joints: ten years of experimental and clinical experience. J Bone Joint Surg Am 85-A Suppl (2003) 225-232
    • (2003) J Bone Joint Surg Am , vol.85 -A , Issue.SUPPL , pp. 225-232
    • Hangody, L.1    Fules, P.2
  • 72
    • 0346963014 scopus 로고    scopus 로고
    • Retroviral delivery of Noggin inhibits the formation of heterotopic ossification induced by BMP-4, demineralized bonematrix, and trauma in an animal model
    • Hannallah D., Peng H., Young B., et al. Retroviral delivery of Noggin inhibits the formation of heterotopic ossification induced by BMP-4, demineralized bonematrix, and trauma in an animal model. J Bone Joint Surg Am 86-A 1 (2004) 80-91
    • (2004) J Bone Joint Surg Am , vol.86 -A , Issue.1 , pp. 80-91
    • Hannallah, D.1    Peng, H.2    Young, B.3
  • 73
    • 11044221899 scopus 로고    scopus 로고
    • Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model
    • Haupt J.L., Frisbie D.D., McIlwraith C.W., et al. Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model. J Orthop Res 23 1 (2005) 118-126
    • (2005) J Orthop Res , vol.23 , Issue.1 , pp. 118-126
    • Haupt, J.L.1    Frisbie, D.D.2    McIlwraith, C.W.3
  • 74
    • 0038750577 scopus 로고    scopus 로고
    • Clinical applications of growth factors for articular cartilage repair
    • Hickey D.G., Frenkel S.R., and Di Cesare P.E. Clinical applications of growth factors for articular cartilage repair. Am J Orthop 32 2 (2003) 70-76
    • (2003) Am J Orthop , vol.32 , Issue.2 , pp. 70-76
    • Hickey, D.G.1    Frenkel, S.R.2    Di Cesare, P.E.3
  • 75
    • 0037869555 scopus 로고    scopus 로고
    • Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7
    • Hidaka C., Goodrich L.R., Chen C.T., et al. Acceleration of cartilage repair by genetically modified chondrocytes over expressing bone morphogenetic protein-7. J Orthop Res 21 4 (2003) 573-583
    • (2003) J Orthop Res , vol.21 , Issue.4 , pp. 573-583
    • Hidaka, C.1    Goodrich, L.R.2    Chen, C.T.3
  • 76
    • 0034777917 scopus 로고    scopus 로고
    • BMP signaling pathways in cartilage and bone formation
    • Hoffmann A., and Gross G. BMP signaling pathways in cartilage and bone formation. Crit Rev Eukaryot Gene Expr 11 1-3 (2001) 23-45
    • (2001) Crit Rev Eukaryot Gene Expr , vol.11 , Issue.1-3 , pp. 23-45
    • Hoffmann, A.1    Gross, G.2
  • 77
    • 0037084463 scopus 로고    scopus 로고
    • The T-box transcription factor Brachyury mediates cartilage development in mesenchymal stem cell line C3H10T1/2
    • Hoffmann A., Czichos S., Kaps C., et al. The T-box transcription factor Brachyury mediates cartilage development in mesenchymal stem cell line C3H10T1/2. J Cell Sci 115 Pt 4 (2002) 769-781
    • (2002) J Cell Sci , vol.115 , Issue.PART 4 , pp. 769-781
    • Hoffmann, A.1    Czichos, S.2    Kaps, C.3
  • 78
    • 0034599678 scopus 로고    scopus 로고
    • Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors
    • HollerN, KataokaT, Bodmer J.L., et al. Development of improved soluble inhibitors of FasL and CD40L based on oligomerized receptors. J Immunol Methods 237 1-2 (2000) 159-173
    • (2000) J Immunol Methods , vol.237 , Issue.1-2 , pp. 159-173
    • HollerN1    KataokaT2    Bodmer, J.L.3
  • 79
    • 5944233768 scopus 로고    scopus 로고
    • Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
    • Holler N., Zaru R., Micheau O., et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1 6 (2000) 489-495
    • (2000) Nat Immunol , vol.1 , Issue.6 , pp. 489-495
    • Holler, N.1    Zaru, R.2    Micheau, O.3
  • 80
    • 0036083985 scopus 로고    scopus 로고
    • Articular cartilage repair: basic science and clinical progress. Areviewof the current status and prospects
    • Hunziker E.B. Articular cartilage repair: basic science and clinical progress. Areviewof the current status and prospects. Osteoarthritis Cartilage 10 6 (2002) 432-463
    • (2002) Osteoarthritis Cartilage , vol.10 , Issue.6 , pp. 432-463
    • Hunziker, E.B.1
  • 81
    • 2942715076 scopus 로고    scopus 로고
    • Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms
    • Hwang S.G., Ryu J.H., Kim I.C., et al. Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms. J Biol Chem 279 25 (2004) 26597-26604
    • (2004) J Biol Chem , vol.279 , Issue.25 , pp. 26597-26604
    • Hwang, S.G.1    Ryu, J.H.2    Kim, I.C.3
  • 82
    • 0031786744 scopus 로고    scopus 로고
    • Adenovirus mediated gene delivery to the joints of guinea pigs
    • Ikeda T., Kubo T., Arai Y., et al. Adenovirus mediated gene delivery to the joints of guinea pigs. J Rheumatol 25 9 (1998) 1666-1673
    • (1998) J Rheumatol , vol.25 , Issue.9 , pp. 1666-1673
    • Ikeda, T.1    Kubo, T.2    Arai, Y.3
  • 83
    • 0036234366 scopus 로고    scopus 로고
    • Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development
    • Ito Y., Bringas Jr. P., Mogharei A., et al. Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development. Dev Dyn 224 1 (2002) 69-78
    • (2002) Dev Dyn , vol.224 , Issue.1 , pp. 69-78
    • Ito, Y.1    Bringas Jr., P.2    Mogharei, A.3
  • 84
    • 0037261123 scopus 로고    scopus 로고
    • Runx2 expression and action in chondrocytes are regulated by retinoid signaling and parathyroid hormone-related peptide (PTHrP)
    • Iwamoto M., Kitagaki J., Tamamura Y., et al. Runx2 expression and action in chondrocytes are regulated by retinoid signaling and parathyroid hormone-related peptide (PTHrP). Osteoarthritis Cartilage 11 1 (2003) 6-15
    • (2003) Osteoarthritis Cartilage , vol.11 , Issue.1 , pp. 6-15
    • Iwamoto, M.1    Kitagaki, J.2    Tamamura, Y.3
  • 85
    • 0032700935 scopus 로고    scopus 로고
    • LeAX. Age-dependent effects of hedgehog protein on chondrocytes
    • Iwasaki M., and Jikko A. LeAX. Age-dependent effects of hedgehog protein on chondrocytes. J Bone Joint Surg Br 81 6 (1999) 1076-1082
    • (1999) J Bone Joint Surg Br , vol.81 , Issue.6 , pp. 1076-1082
    • Iwasaki, M.1    Jikko, A.2
  • 86
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y., Jahagirdar B.N., Reinhardt R.L., et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418 6893 (2002) 41-49
    • (2002) Nature , vol.418 , Issue.6893 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 87
    • 0031942990 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-10 are chondroprotective and decrease mononuclear cell recruitment in human rheumatoid synoviumin vivo
    • Jorgensen C., Apparailly F., Couret I., et al. Interleukin-4 and interleukin-10 are chondroprotective and decrease mononuclear cell recruitment in human rheumatoid synoviumin vivo. Immunology 93 4 (1998) 518-523
    • (1998) Immunology , vol.93 , Issue.4 , pp. 518-523
    • Jorgensen, C.1    Apparailly, F.2    Couret, I.3
  • 88
    • 20244384369 scopus 로고    scopus 로고
    • Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach
    • Kafienah W., Al-Fayez F., Hollander A.P., et al. Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach. Arthritis Rheum 48 3 (2003) 709-718
    • (2003) Arthritis Rheum , vol.48 , Issue.3 , pp. 709-718
    • Kafienah, W.1    Al-Fayez, F.2    Hollander, A.P.3
  • 89
    • 0030893301 scopus 로고    scopus 로고
    • Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: a feasibility study
    • Kang R., Marui T., Ghivizzani S.C., et al. Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: a feasibility study. Osteoarthritis Cartilage 5 2 (1997) 139-143
    • (1997) Osteoarthritis Cartilage , vol.5 , Issue.2 , pp. 139-143
    • Kang, R.1    Marui, T.2    Ghivizzani, S.C.3
  • 90
    • 4344628054 scopus 로고    scopus 로고
    • Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow
    • Katayama R., Wakitani S., Tsumaki N., et al. Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow. Rheumatology (Oxford) 43 8 (2004) 980-985
    • (2004) Rheumatology (Oxford) , vol.43 , Issue.8 , pp. 980-985
    • Katayama, R.1    Wakitani, S.2    Tsumaki, N.3
  • 91
    • 31644440253 scopus 로고    scopus 로고
    • Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo
    • Kaul G., Cucchiarini M., Arntzen D., et al. Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo. J Gene Med 8 1 (2006) 100-111
    • (2006) J Gene Med , vol.8 , Issue.1 , pp. 100-111
    • Kaul, G.1    Cucchiarini, M.2    Arntzen, D.3
  • 92
    • 33645450704 scopus 로고    scopus 로고
    • Cartilage tissue engineering: its potential and uses
    • Kuo C.K., Li W.J., Mauck R.L., et al. Cartilage tissue engineering: its potential and uses. Curr Opin Rheumatol 18 1 (2006) 64-73
    • (2006) Curr Opin Rheumatol , vol.18 , Issue.1 , pp. 64-73
    • Kuo, C.K.1    Li, W.J.2    Mauck, R.L.3
  • 93
    • 33846367391 scopus 로고    scopus 로고
    • Treatment of a fullthickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells
    • Kuroda R., Ishida K., Matsumoto T., et al. Treatment of a fullthickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells. Osteoarthritis Cartilage 15 2 (2007) 226-231
    • (2007) Osteoarthritis Cartilage , vol.15 , Issue.2 , pp. 226-231
    • Kuroda, R.1    Ishida, K.2    Matsumoto, T.3
  • 94
    • 0033566812 scopus 로고    scopus 로고
    • Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees
    • Lechman E.R., Jaffurs D., Ghivizzani S.C., et al. Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees. J Immunol 163 4 (1999) 2202-2208
    • (1999) J Immunol , vol.163 , Issue.4 , pp. 2202-2208
    • Lechman, E.R.1    Jaffurs, D.2    Ghivizzani, S.C.3
  • 95
    • 0034812672 scopus 로고    scopus 로고
    • Regeneration of hyaline cartilage by cell-mediated gene therapy using transforming growth factor beta 1-producing fibroblasts
    • Lee K.H., Song S.U., Hwang T.S., et al. Regeneration of hyaline cartilage by cell-mediated gene therapy using transforming growth factor beta 1-producing fibroblasts. Hum Gene Ther 12 14 (2001) 1805-1813
    • (2001) Hum Gene Ther , vol.12 , Issue.14 , pp. 1805-1813
    • Lee, K.H.1    Song, S.U.2    Hwang, T.S.3
  • 96
    • 0029778219 scopus 로고    scopus 로고
    • A 47-bp sequence of the first intron of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte Expression
    • Lefebvre V., Mukhopadhyay K., Zhou G., et al. A 47-bp sequence of the first intron of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte Expression. Ann NY Acad Sci 785 (1996) 284-287
    • (1996) Ann NY Acad Sci , vol.785 , pp. 284-287
    • Lefebvre, V.1    Mukhopadhyay, K.2    Zhou, G.3
  • 97
    • 0032189223 scopus 로고    scopus 로고
    • A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene
    • Lefebvre V., Li P., and de Crombrugghe B. A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. Embo J 17 19 (1998) 5718-5733
    • (1998) Embo J , vol.17 , Issue.19 , pp. 5718-5733
    • Lefebvre, V.1    Li, P.2    de Crombrugghe, B.3
  • 98
    • 0034846904 scopus 로고    scopus 로고
    • L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway
    • Lefebvre V., Behringer R.R., and de Crombrugghe B. L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. Osteoarthritis Cartilage 9 Suppl A (2001) 69-75
    • (2001) Osteoarthritis Cartilage , vol.9 , Issue.SUPPL. A , pp. 69-75
    • Lefebvre, V.1    Behringer, R.R.2    de Crombrugghe, B.3
  • 99
    • 2342511482 scopus 로고    scopus 로고
    • Transduction of passaged human articular chondrocytes with adenoviral, retroviral, and lentiviral vectors and the effects of enhanced expression of SOX9
    • Li Y., Tew S.R., Russell A.M., et al. Transduction of passaged human articular chondrocytes with adenoviral, retroviral, and lentiviral vectors and the effects of enhanced expression of SOX9. Tissue Eng 10 3-4 (2004) 575-584
    • (2004) Tissue Eng , vol.10 , Issue.3-4 , pp. 575-584
    • Li, Y.1    Tew, S.R.2    Russell, A.M.3
  • 100
    • 0033771098 scopus 로고    scopus 로고
    • Marrow transplantation and targeted gene therapy to the skeleton
    • Lian J.B., Stein G.S., Stein J.L., et al. Marrow transplantation and targeted gene therapy to the skeleton. ClinOrthop Relat Res 379 Suppl (2000) 146-155
    • (2000) ClinOrthop Relat Res , vol.379 , Issue.SUPPL , pp. 146-155
    • Lian, J.B.1    Stein, G.S.2    Stein, J.L.3
  • 101
    • 0033036389 scopus 로고    scopus 로고
    • The role of nitric oxide in articular cartilage damage
    • Lotz M. The role of nitric oxide in articular cartilage damage. Rheum Dis Clin North Am 25 2 (1999) 269-282
    • (1999) Rheum Dis Clin North Am , vol.25 , Issue.2 , pp. 269-282
    • Lotz, M.1
  • 103
    • 0034792290 scopus 로고    scopus 로고
    • Cytokines in cartilage injury and repair
    • Lotz M. Cytokines in cartilage injury and repair. Clin Orthop Relat Res 391 Suppl (2001) S108-S115
    • (2001) Clin Orthop Relat Res , vol.391 , Issue.SUPPL
    • Lotz, M.1
  • 104
    • 0032853313 scopus 로고    scopus 로고
    • Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction
    • Lubberts E., Joosten L.A., van Den Bersselaar L., et al. Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction. J Immunol 163 8 (1999) 4546-4556
    • (1999) J Immunol , vol.163 , Issue.8 , pp. 4546-4556
    • Lubberts, E.1    Joosten, L.A.2    van Den Bersselaar, L.3
  • 105
    • 0034066110 scopus 로고    scopus 로고
    • Intraarticular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw
    • Lubberts E., Joosten L.A., Van Den Bersselaar L., et al. Intraarticular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw. Clin Exp Immunol 120 2 (2000) 375-383
    • (2000) Clin Exp Immunol , vol.120 , Issue.2 , pp. 375-383
    • Lubberts, E.1    Joosten, L.A.2    Van Den Bersselaar, L.3
  • 106
    • 0033994254 scopus 로고    scopus 로고
    • Efficient lipid-mediated gene transfer to articular chondrocytes
    • Madry H., and Trippel S.B. Efficient lipid-mediated gene transfer to articular chondrocytes. Gene Ther 7 4 (2000) 286-291
    • (2000) Gene Ther , vol.7 , Issue.4 , pp. 286-291
    • Madry, H.1    Trippel, S.B.2
  • 107
    • 0034782732 scopus 로고    scopus 로고
    • Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation
    • Madry H., Zurakowski D., and Trippel S.B. Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation. Gene Ther 8 19 (2001) 1443-1449
    • (2001) Gene Ther , vol.8 , Issue.19 , pp. 1443-1449
    • Madry, H.1    Zurakowski, D.2    Trippel, S.B.3
  • 108
    • 1342342795 scopus 로고    scopus 로고
    • Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system
    • Madry H., Cucchiarini M., Stein U., et al. Sustained transgene expression in cartilage defects in vivo after transplantation of articular chondrocytes modified by lipid-mediated gene transfer in a gel suspension delivery system. J Gene Med 5 6 (2003) 502-509
    • (2003) J Gene Med , vol.5 , Issue.6 , pp. 502-509
    • Madry, H.1    Cucchiarini, M.2    Stein, U.3
  • 109
    • 4644244444 scopus 로고    scopus 로고
    • Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation
    • Madry H., Emkey G., Zurakowski D., et al. Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation. J Gene Med 6 2 (2004) 238-245
    • (2004) J Gene Med , vol.6 , Issue.2 , pp. 238-245
    • Madry, H.1    Emkey, G.2    Zurakowski, D.3
  • 110
    • 23744467071 scopus 로고    scopus 로고
    • Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I)
    • Madry H., Kaul G., Cucchiarini M., et al. Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I). Gene Ther 12 15 (2005) 1171-1179
    • (2005) Gene Ther , vol.12 , Issue.15 , pp. 1171-1179
    • Madry, H.1    Kaul, G.2    Cucchiarini, M.3
  • 111
    • 0027527343 scopus 로고
    • Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases
    • Maier R., Ganu V., and Lotz M. Interleukin-11, an inducible cytokine in human articular chondrocytes and synoviocytes, stimulates the production of the tissue inhibitor of metalloproteinases. J Biol Chem 268 29 (1993) 21527-21532
    • (1993) J Biol Chem , vol.268 , Issue.29 , pp. 21527-21532
    • Maier, R.1    Ganu, V.2    Lotz, M.3
  • 112
    • 0028113983 scopus 로고
    • Inducible nitric oxide synthase from human articular chondrocytes: cDNA cloning and analysis of mRNA expression
    • Maier R., Bilbe G., Rediske J., et al. Inducible nitric oxide synthase from human articular chondrocytes: cDNA cloning and analysis of mRNA expression. Biochim Biophys Acta 1208 1 (1994) 145-150
    • (1994) Biochim Biophys Acta , vol.1208 , Issue.1 , pp. 145-150
    • Maier, R.1    Bilbe, G.2    Rediske, J.3
  • 113
    • 0030071084 scopus 로고    scopus 로고
    • Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA
    • Makarov S.S., Olsen J.C., Johnston W.N., et al. Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA. Proc Natl Acad Sci USA 93 1 (1996) 402-406
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.1 , pp. 402-406
    • Makarov, S.S.1    Olsen, J.C.2    Johnston, W.N.3
  • 114
    • 30444461215 scopus 로고    scopus 로고
    • Cartilage repair: generations of autologous chondrocyte transplantation
    • Marlovits S., Zeller P., Singer P., et al. Cartilage repair: generations of autologous chondrocyte transplantation. Eur J Radiol 57 1 (2006) 24-31
    • (2006) Eur J Radiol , vol.57 , Issue.1 , pp. 24-31
    • Marlovits, S.1    Zeller, P.2    Singer, P.3
  • 115
    • 1842781743 scopus 로고    scopus 로고
    • Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence
    • Martin J.A., Klingelhutz A.J., Moussavi-Harami F., et al. Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence. J Gerontol A Biol Sci Med Sci 59 4 (2004) 324-337
    • (2004) J Gerontol A Biol Sci Med Sci , vol.59 , Issue.4 , pp. 324-337
    • Martin, J.A.1    Klingelhutz, A.J.2    Moussavi-Harami, F.3
  • 116
    • 0031718624 scopus 로고    scopus 로고
    • Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: potential utility in gene therapy for osteochondral repair
    • Mason J.M., Grande D.A., Barcia M., et al. Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: potential utility in gene therapy for osteochondral repair. Gene Ther 5 8 (1998) 1098-1104
    • (1998) Gene Ther , vol.5 , Issue.8 , pp. 1098-1104
    • Mason, J.M.1    Grande, D.A.2    Barcia, M.3
  • 117
    • 0033779509 scopus 로고    scopus 로고
    • Cartilage and bone regeneration using gene-enhanced tissue engineering [In Process Citation]
    • Mason J.M., Breitbart A.S., Barcia M., et al. Cartilage and bone regeneration using gene-enhanced tissue engineering [In Process Citation]. Clin Orthop 379 Suppl (2000) 171-178
    • (2000) Clin Orthop , vol.379 , Issue.SUPPL , pp. 171-178
    • Mason, J.M.1    Breitbart, A.S.2    Barcia, M.3
  • 118
    • 33646190753 scopus 로고    scopus 로고
    • Expression of mutant cartilage oligomeric matrix protein in human chondrocytes induces the pseudoachondroplasia phenotype
    • Merritt T.M., Alcorn J.L., Haynes R., et al. Expression of mutant cartilage oligomeric matrix protein in human chondrocytes induces the pseudoachondroplasia phenotype. JOrthop Res 24 4 (2006) 700-707
    • (2006) JOrthop Res , vol.24 , Issue.4 , pp. 700-707
    • Merritt, T.M.1    Alcorn, J.L.2    Haynes, R.3
  • 119
    • 0033763544 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints
    • Mi Z., Ghivizzani S.C., Lechman E.R., et al. Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints. Arthritis Rheum 43 11 (2000) 2563-2570
    • (2000) Arthritis Rheum , vol.43 , Issue.11 , pp. 2563-2570
    • Mi, Z.1    Ghivizzani, S.C.2    Lechman, E.R.3
  • 120
    • 0042622575 scopus 로고    scopus 로고
    • Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees
    • Mi Z., Ghivizzani S.C., Lechman E., et al. Adverse effects of adenovirus-mediated gene transfer of human transforming growth factor beta 1 into rabbit knees. Arthritis Res Ther 5 3 (2003) 132-139
    • (2003) Arthritis Res Ther , vol.5 , Issue.3 , pp. 132-139
    • Mi, Z.1    Ghivizzani, S.C.2    Lechman, E.3
  • 121
    • 0030972757 scopus 로고    scopus 로고
    • Current concepts in the treatment of articular cartilage defects
    • Minas T., and Nehrer S. Current concepts in the treatment of articular cartilage defects. Orthopedics 20 6 (1997) 525-538
    • (1997) Orthopedics , vol.20 , Issue.6 , pp. 525-538
    • Minas, T.1    Nehrer, S.2
  • 122
    • 0032609218 scopus 로고    scopus 로고
    • The role of cartilage repair techniques, including chondrocyte transplantation, in focal chondral knee damage
    • Minas T. The role of cartilage repair techniques, including chondrocyte transplantation, in focal chondral knee damage. Instr Course Lect 48 (1999) 629-643
    • (1999) Instr Course Lect , vol.48 , pp. 629-643
    • Minas, T.1
  • 123
    • 0032923470 scopus 로고    scopus 로고
    • Advanced techniques in autologous chondrocyte transplantation
    • Minas T., and Peterson L. Advanced techniques in autologous chondrocyte transplantation. Clin Sports Med 18 1 (1999) 13-44
    • (1999) Clin Sports Med , vol.18 , Issue.1 , pp. 13-44
    • Minas, T.1    Peterson, L.2
  • 124
    • 0034747252 scopus 로고    scopus 로고
    • BMP and Ihh/ PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation
    • Minina E., Wenzel H.M., Kreschel C., et al. BMP and Ihh/ PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development 128 22 (2001) 4523-4534
    • (2001) Development , vol.128 , Issue.22 , pp. 4523-4534
    • Minina, E.1    Wenzel, H.M.2    Kreschel, C.3
  • 125
    • 13844257292 scopus 로고    scopus 로고
    • Cellular lifespan and senescence signaling in embryonic stem cells
    • Miura T., Mattson M.P., and Rao M.S. Cellular lifespan and senescence signaling in embryonic stem cells. Aging Cell 3 6 (2004) 333-343
    • (2004) Aging Cell , vol.3 , Issue.6 , pp. 333-343
    • Miura, T.1    Mattson, M.P.2    Rao, M.S.3
  • 126
    • 0344882568 scopus 로고    scopus 로고
    • Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model
    • Muller-Ladner U., Evans C.H., Franklin B.N., et al. Gene transfer of cytokine inhibitors into human synovial fibroblasts in the SCID mouse model. Arthritis Rheum 42 3 (1999) 490-497
    • (1999) Arthritis Rheum , vol.42 , Issue.3 , pp. 490-497
    • Muller-Ladner, U.1    Evans, C.H.2    Franklin, B.N.3
  • 127
    • 0032413011 scopus 로고    scopus 로고
    • Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
    • Naski M.C., Colvin J.S., Coffin J.D., et al. Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3. Development 125 24 (1998) 4977-4988
    • (1998) Development , vol.125 , Issue.24 , pp. 4977-4988
    • Naski, M.C.1    Colvin, J.S.2    Coffin, J.D.3
  • 128
    • 33644973673 scopus 로고    scopus 로고
    • FGF signaling in skeletal development
    • Naski M.C., and Ornitz D.M. FGF signaling in skeletal development. Front Biosci 3 (1998) 781-794
    • (1998) Front Biosci , vol.3 , pp. 781-794
    • Naski, M.C.1    Ornitz, D.M.2
  • 129
    • 18744405989 scopus 로고    scopus 로고
    • Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway
    • Neumann E., Judex M., Kullmann F., et al. Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway. Gene Ther 9 22 (2002) 1508-1519
    • (2002) Gene Ther , vol.9 , Issue.22 , pp. 1508-1519
    • Neumann, E.1    Judex, M.2    Kullmann, F.3
  • 130
    • 0032838154 scopus 로고    scopus 로고
    • Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites
    • Nixon A.J., Fortier L.A., Williams J., et al. Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin composites. J Orthop Res 17 4 (1999) 475-487
    • (1999) J Orthop Res , vol.17 , Issue.4 , pp. 475-487
    • Nixon, A.J.1    Fortier, L.A.2    Williams, J.3
  • 131
    • 0035073106 scopus 로고    scopus 로고
    • Exogenous insulinlike growth factor-I stimulates an autoinductive IGF-I autocrine/paracrine response in chondrocytes
    • Nixon A.J., Saxer R.A., and Brower-Toland B.D. Exogenous insulinlike growth factor-I stimulates an autoinductive IGF-I autocrine/paracrine response in chondrocytes. J Orthop Res 19 1 (2001) 26-32
    • (2001) J Orthop Res , vol.19 , Issue.1 , pp. 26-32
    • Nixon, A.J.1    Saxer, R.A.2    Brower-Toland, B.D.3
  • 132
    • 13244269894 scopus 로고    scopus 로고
    • Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy
    • Nixon A.J., Haupt J.L., Frisbie D.D., et al. Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy. Gene Ther 12 2 (2005) 177-186
    • (2005) Gene Ther , vol.12 , Issue.2 , pp. 177-186
    • Nixon, A.J.1    Haupt, J.L.2    Frisbie, D.D.3
  • 133
    • 1542294411 scopus 로고    scopus 로고
    • Adenovirus mediated BMP-13 gene transfer induces chondrogenic differentiation of murine mesenchymal progenitor cells
    • Nochi H., Sung J.H., Lou J., et al. Adenovirus mediated BMP-13 gene transfer induces chondrogenic differentiation of murine mesenchymal progenitor cells. J Bone Miner Res 19 1 (2004) 111-122
    • (2004) J Bone Miner Res , vol.19 , Issue.1 , pp. 111-122
    • Nochi, H.1    Sung, J.H.2    Lou, J.3
  • 134
    • 0036377961 scopus 로고    scopus 로고
    • Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells
    • Noth U., OsyczkaAM, Tuli R., et al. Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells. J Orthop Res 20 5 (2002) 1060-1069
    • (2002) J Orthop Res , vol.20 , Issue.5 , pp. 1060-1069
    • Noth, U.1    OsyczkaAM2    Tuli, R.3
  • 135
    • 0036189787 scopus 로고    scopus 로고
    • In vitro engineered cartilage constructs produced by press-coating biodegradable polymer with human mesenchymal stem cells
    • Noth U., Tuli R., Osyczka A.M., et al. In vitro engineered cartilage constructs produced by press-coating biodegradable polymer with human mesenchymal stem cells. Tissue Eng 8 1 (2002) 131-144
    • (2002) Tissue Eng , vol.8 , Issue.1 , pp. 131-144
    • Noth, U.1    Tuli, R.2    Osyczka, A.M.3
  • 136
    • 0033771094 scopus 로고    scopus 로고
    • Vector systems for gene transfer to joints
    • Oligino T.J., Yao Q., Ghivizzani S.C., et al. Vector systems for gene transfer to joints. Clin Orthop 379 Suppl (2000) 17-30
    • (2000) Clin Orthop , vol.379 , Issue.SUPPL , pp. 17-30
    • Oligino, T.J.1    Yao, Q.2    Ghivizzani, S.C.3
  • 137
    • 0032845120 scopus 로고    scopus 로고
    • Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis
    • Oligino T.J., Ghivizzani S.C., Wolfe D., et al. Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis. Gene Ther 6 10 (1999) 1713-1720
    • (1999) Gene Ther , vol.6 , Issue.10 , pp. 1713-1720
    • Oligino, T.J.1    Ghivizzani, S.C.2    Wolfe, D.3
  • 138
    • 22644444720 scopus 로고    scopus 로고
    • Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro
    • Palmer G.D., Steinert A., Pascher A., et al. Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro. Mol Therapy 12 2 (2005) 219-228
    • (2005) Mol Therapy , vol.12 , Issue.2 , pp. 219-228
    • Palmer, G.D.1    Steinert, A.2    Pascher, A.3
  • 139
    • 31644434203 scopus 로고    scopus 로고
    • Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum- and fat-derived cells
    • Park J., Gelse K., Frank S., et al. Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum- and fat-derived cells. J Gene Med 8 1 (2006) 112-125
    • (2006) J Gene Med , vol.8 , Issue.1 , pp. 112-125
    • Park, J.1    Gelse, K.2    Frank, S.3
  • 140
    • 10744229809 scopus 로고    scopus 로고
    • Gene delivery to cartilage defects using coagulated bone marrow aspirate
    • Pascher A., Palmer G.D., Steinert A.F., et al. Gene delivery to cartilage defects using coagulated bone marrow aspirate. Gene Ther 11 2 (2004) 133-141
    • (2004) Gene Ther , vol.11 , Issue.2 , pp. 133-141
    • Pascher, A.1    Palmer, G.D.2    Steinert, A.F.3
  • 141
    • 4344595112 scopus 로고    scopus 로고
    • Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model
    • Pascher A., Steinert A.F., Palmer G.D., et al. Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model. Mol Ther 10 2 (2004) 327-336
    • (2004) Mol Ther , vol.10 , Issue.2 , pp. 327-336
    • Pascher, A.1    Steinert, A.F.2    Palmer, G.D.3
  • 142
    • 0033562850 scopus 로고    scopus 로고
    • Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation
    • Pathi S., Rutenberg J.B., Johnson R.L., et al. Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation. Dev Biol 209 2 (1999) 239-253
    • (1999) Dev Biol , vol.209 , Issue.2 , pp. 239-253
    • Pathi, S.1    Rutenberg, J.B.2    Johnson, R.L.3
  • 143
    • 0030961873 scopus 로고    scopus 로고
    • In vivo suppression of early experimental osteoarthritis by interleukin- 1 receptor antagonist using gene therapy
    • Pelletier J.P., Caron J.P., Evans C., et al. In vivo suppression of early experimental osteoarthritis by interleukin- 1 receptor antagonist using gene therapy. Arthritis Rheum 40 6 (1997) 1012-1019
    • (1997) Arthritis Rheum , vol.40 , Issue.6 , pp. 1012-1019
    • Pelletier, J.P.1    Caron, J.P.2    Evans, C.3
  • 144
    • 0036155852 scopus 로고    scopus 로고
    • Autologous chondrocyte transplantation. Biomechanics and long-term durability
    • Peterson L., Brittberg M., Kiviranta I., et al. Autologous chondrocyte transplantation. Biomechanics and long-term durability. Am J Sports Med 30 1 (2002) 2-12
    • (2002) Am J Sports Med , vol.30 , Issue.1 , pp. 2-12
    • Peterson, L.1    Brittberg, M.2    Kiviranta, I.3
  • 145
    • 0038071965 scopus 로고    scopus 로고
    • Treatment of osteochondritis dissecans of the knee with autologous chondrocyte transplantation: results at two to ten years
    • Peterson L., Minas T., Brittberg M., et al. Treatment of osteochondritis dissecans of the knee with autologous chondrocyte transplantation: results at two to ten years. J Bone Joint Surg Am 85-A Suppl (2003) 217-224
    • (2003) J Bone Joint Surg Am , vol.85 -A , Issue.SUPPL , pp. 217-224
    • Peterson, L.1    Minas, T.2    Brittberg, M.3
  • 146
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger M.F., Mackay A.M., Beck S.C., et al. Multilineage potential of adult human mesenchymal stem cells. Science 284 5411 (1999) 143-147
    • (1999) Science , vol.284 , Issue.5411 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 147
    • 0035527591 scopus 로고    scopus 로고
    • Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells
    • Prockop D.J., and Sekiya IColter D.C. Isolation and characterization of rapidly self-renewing stem cells from cultures of human marrow stromal cells. Cytotherapy 3 5 (2001) 393-396
    • (2001) Cytotherapy , vol.3 , Issue.5 , pp. 393-396
    • Prockop, D.J.1    Sekiya IColter, D.C.2
  • 149
    • 0141727395 scopus 로고    scopus 로고
    • Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis
    • Rudolphi K., Gerwin N., Verzijl N., et al. Pralnacasan, an inhibitor of interleukin-1beta converting enzyme, reduces joint damage in two murine models of osteoarthritis. Osteoarthritis Cartilage 11 10 (2003) 738-746
    • (2003) Osteoarthritis Cartilage , vol.11 , Issue.10 , pp. 738-746
    • Rudolphi, K.1    Gerwin, N.2    Verzijl, N.3
  • 150
    • 0036247817 scopus 로고    scopus 로고
    • Delivery of plasmid DNA to articular chondrocytes via novel collagenglycosaminoglycan matrices
    • Samuel R.E., Lee C.R., Ghivizzani S.C., et al. Delivery of plasmid DNA to articular chondrocytes via novel collagenglycosaminoglycan matrices. Hum Gene Ther 13 7 (2002) 791-802
    • (2002) Hum Gene Ther , vol.13 , Issue.7 , pp. 791-802
    • Samuel, R.E.1    Lee, C.R.2    Ghivizzani, S.C.3
  • 151
    • 0242606953 scopus 로고    scopus 로고
    • Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGFbeta- mediated chondrocyte proliferation and proteoglycan synthesis
    • Scharstuhl A., Diepens R., Lensen J., et al. Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGFbeta- mediated chondrocyte proliferation and proteoglycan synthesis. Osteoarthritis Cartilage 11 11 (2003) 773-782
    • (2003) Osteoarthritis Cartilage , vol.11 , Issue.11 , pp. 773-782
    • Scharstuhl, A.1    Diepens, R.2    Lensen, J.3
  • 152
    • 0346220031 scopus 로고    scopus 로고
    • Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/ bone morphogenetic protein inhibitors during experimental osteoarthritis
    • Scharstuhl A., Vitters E.L., van der Kraan P.M., et al. Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/ bone morphogenetic protein inhibitors during experimental osteoarthritis. Arthritis Rheum 48 12 (2003) 3442-3451
    • (2003) Arthritis Rheum , vol.48 , Issue.12 , pp. 3442-3451
    • Scharstuhl, A.1    Vitters, E.L.2    van der Kraan, P.M.3
  • 153
    • 33646125855 scopus 로고    scopus 로고
    • A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair
    • Schmidt M.B., Chen E.H., and Lynch S.E. A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair. Osteoarthritis Cartilage 14 5 (2006) 403-412
    • (2006) Osteoarthritis Cartilage , vol.14 , Issue.5 , pp. 403-412
    • Schmidt, M.B.1    Chen, E.H.2    Lynch, S.E.3
  • 154
    • 18844447203 scopus 로고    scopus 로고
    • Comparison of effect of BMP-2, -4, and -6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma
    • Sekiya I., Larson B.L., Vuoristo J.T., et al. Comparison of effect of BMP-2, -4, and -6 on in vitro cartilage formation of human adult stem cells from bone marrow stroma. Cell Tissue Res 320 2 (2005) 269-276
    • (2005) Cell Tissue Res , vol.320 , Issue.2 , pp. 269-276
    • Sekiya, I.1    Larson, B.L.2    Vuoristo, J.T.3
  • 155
    • 0033954799 scopus 로고    scopus 로고
    • Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2)
    • Sellers R.S., Zhang R., Glasson S.S., et al. Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2). J Bone Joint Surg Am 82 2 (2000) 151-160
    • (2000) J Bone Joint Surg Am , vol.82 , Issue.2 , pp. 151-160
    • Sellers, R.S.1    Zhang, R.2    Glasson, S.S.3
  • 156
    • 33846374756 scopus 로고    scopus 로고
    • Alteration of matrix glycosaminoglycans diminishes articular chondrocytes' response to a canonical Wnt signal
    • Shortkroff S., and Yates K.E. Alteration of matrix glycosaminoglycans diminishes articular chondrocytes' response to a canonical Wnt signal. Osteoarthritis Cartilage 15 2 (2007) 147-154
    • (2007) Osteoarthritis Cartilage , vol.15 , Issue.2 , pp. 147-154
    • Shortkroff, S.1    Yates, K.E.2
  • 157
    • 0034232660 scopus 로고    scopus 로고
    • Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes
    • Shuler F.D., Georgescu H.I., Niyibizi C., et al. Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes. J Orthop Res 18 4 (2000) 585-592
    • (2000) J Orthop Res , vol.18 , Issue.4 , pp. 585-592
    • Shuler, F.D.1    Georgescu, H.I.2    Niyibizi, C.3
  • 158
    • 20044364559 scopus 로고    scopus 로고
    • Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development
    • Smith N., Dong Y., Lian J.B., et al. Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol 203 1 (2005) 133-143
    • (2005) J Cell Physiol , vol.203 , Issue.1 , pp. 133-143
    • Smith, N.1    Dong, Y.2    Lian, J.B.3
  • 159
    • 0034091315 scopus 로고    scopus 로고
    • Genetic enhancement of matrix synthesis by articular chondrocytes: comparison of different growth factor genes in the presence and absence of interleukin-1
    • Smith P., Shuler F.D., Georgescu H.I., et al. Genetic enhancement of matrix synthesis by articular chondrocytes: comparison of different growth factor genes in the presence and absence of interleukin-1. Arthritis Rheum 43 5 (2000) 1156-1164
    • (2000) Arthritis Rheum , vol.43 , Issue.5 , pp. 1156-1164
    • Smith, P.1    Shuler, F.D.2    Georgescu, H.I.3
  • 160
    • 2342522072 scopus 로고    scopus 로고
    • Electric field-induced molecular vibration for noninvasive, high-efficiency DNA transfection
    • Song L., Chau L., Sakamoto Y., et al. Electric field-induced molecular vibration for noninvasive, high-efficiency DNA transfection. Mol Ther 9 4 (2004) 607-616
    • (2004) Mol Ther , vol.9 , Issue.4 , pp. 607-616
    • Song, L.1    Chau, L.2    Sakamoto, Y.3
  • 161
    • 0034786841 scopus 로고    scopus 로고
    • Microfracture: surgical technique and rehabilitation to treat chondral defects
    • Steadman J.R., Rodkey W.G., and Rodrigo J.J. Microfracture: surgical technique and rehabilitation to treat chondral defects. Clin Orthop Relat Res 391 Suppl (2001) 362-369
    • (2001) Clin Orthop Relat Res , vol.391 , Issue.SUPPL , pp. 362-369
    • Steadman, J.R.1    Rodkey, W.G.2    Rodrigo, J.J.3
  • 162
    • 0036594385 scopus 로고    scopus 로고
    • Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes
    • Steadman J.R., Rodkey W.G., and Briggs K.K. Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes. J Knee Surg 15 3 (2002) 170-176
    • (2002) J Knee Surg , vol.15 , Issue.3 , pp. 170-176
    • Steadman, J.R.1    Rodkey, W.G.2    Briggs, K.K.3
  • 163
    • 10744225005 scopus 로고    scopus 로고
    • Chondrogenic differentiation of mesenchymal progenitor cells encapsulated in ultrahigh-viscosity alginate
    • Steinert A., Weber M., Dimmler A., et al. Chondrogenic differentiation of mesenchymal progenitor cells encapsulated in ultrahigh-viscosity alginate. J Orthop Res 21 6 (2003) 1090-1097
    • (2003) J Orthop Res , vol.21 , Issue.6 , pp. 1090-1097
    • Steinert, A.1    Weber, M.2    Dimmler, A.3
  • 164
    • 34250197868 scopus 로고    scopus 로고
    • Gene Therapy in the Treatment of Cartilage Injury
    • Mirzajan R. (Ed), Thieme Medical Publishers, New York
    • Steinert A., Palmer G., Ghivizzani S.C., et al. Gene Therapy in the Treatment of Cartilage Injury. In: Mirzajan R. (Ed). Cartilage Injury in the Athlete (2006), Thieme Medical Publishers, New York 297-308
    • (2006) Cartilage Injury in the Athlete , pp. 297-308
    • Steinert, A.1    Palmer, G.2    Ghivizzani, S.C.3
  • 165
    • 16844375144 scopus 로고    scopus 로고
    • Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression
    • Tavella S., Biticchi R., Schito A., et al. Targeted expression of SHH affects chondrocyte differentiation, growth plate organization, and Sox9 expression. J Bone Miner Res 19 10 (2004) 1678-1688
    • (2004) J Bone Miner Res , vol.19 , Issue.10 , pp. 1678-1688
    • Tavella, S.1    Biticchi, R.2    Schito, A.3
  • 166
    • 0034791648 scopus 로고    scopus 로고
    • Differences in repair responses between immature and mature cartilage
    • Tew S., Redman S., Kwan A., et al. Differences in repair responses between immature and mature cartilage. Clin Orthop Relat Res 391 Suppl (2001) 142-152
    • (2001) Clin Orthop Relat Res , vol.391 , Issue.SUPPL , pp. 142-152
    • Tew, S.1    Redman, S.2    Kwan, A.3
  • 167
    • 12144276564 scopus 로고    scopus 로고
    • Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes
    • Tew S.R., Li Y., Pothacharoen P., et al. Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes. Osteoarthritis Cartilage 13 1 (2005) 80-89
    • (2005) Osteoarthritis Cartilage , vol.13 , Issue.1 , pp. 80-89
    • Tew, S.R.1    Li, Y.2    Pothacharoen, P.3
  • 168
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • Thomas C.E., Ehrhardt A., and Kay M.A. Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet 4 5 (2003) 346-358
    • (2003) Nat Rev Genet , vol.4 , Issue.5 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3
  • 169
    • 33750459732 scopus 로고    scopus 로고
    • Up-regulation of cartilage oligomeric matrix protein gene expression by insulin-like growth factor- I revealed by real-time reverse transcription-polymerase chain reaction
    • Tian H., and Stogiannidis I. Up-regulation of cartilage oligomeric matrix protein gene expression by insulin-like growth factor- I revealed by real-time reverse transcription-polymerase chain reaction. Acta Biochim Biophys Sin (Shanghai) 38 10 (2006) 677-682
    • (2006) Acta Biochim Biophys Sin (Shanghai) , vol.38 , Issue.10 , pp. 677-682
    • Tian, H.1    Stogiannidis, I.2
  • 170
    • 0030982313 scopus 로고    scopus 로고
    • In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes
    • Tomita T., Hashimoto H., Tomita N., et al. In vivo direct gene transfer into articular cartilage by intraarticular injection mediated by HVJ (Sendai virus) and liposomes. Arthritis Rheum 40 5 (1997) 901-906
    • (1997) Arthritis Rheum , vol.40 , Issue.5 , pp. 901-906
    • Tomita, T.1    Hashimoto, H.2    Tomita, N.3
  • 171
    • 1342263759 scopus 로고    scopus 로고
    • Gene-based approaches for the repair of articular cartilage
    • Trippel S.B., Ghivizzani S.C., and Nixon A.J. Gene-based approaches for the repair of articular cartilage. Gene Ther 11 4 (2004) 351-359
    • (2004) Gene Ther , vol.11 , Issue.4 , pp. 351-359
    • Trippel, S.B.1    Ghivizzani, S.C.2    Nixon, A.J.3
  • 172
    • 0037423736 scopus 로고    scopus 로고
    • Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells
    • Tsuchiya H., Kitoh H., Sugiura F., et al. Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun 301 2 (2003) 338-343
    • (2003) Biochem Biophys Res Commun , vol.301 , Issue.2 , pp. 338-343
    • Tsuchiya, H.1    Kitoh, H.2    Sugiura, F.3
  • 173
    • 0033545218 scopus 로고    scopus 로고
    • Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation
    • Tsumaki N., Tanaka K., Arikawa-Hirasawa E., et al. Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation. J Cell Biol 144 1 (1999) 161-173
    • (1999) J Cell Biol , vol.144 , Issue.1 , pp. 161-173
    • Tsumaki, N.1    Tanaka, K.2    Arikawa-Hirasawa, E.3
  • 174
    • 0035984709 scopus 로고    scopus 로고
    • Boning up on telomerase
    • Tuan R. Boning up on telomerase. Nat Biotechnol 20 6 (2002) 560-561
    • (2002) Nat Biotechnol , vol.20 , Issue.6 , pp. 560-561
    • Tuan, R.1
  • 175
    • 0037963685 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells and cell-based tissue engineering
    • Tuan R.S., Boland G., and Tuli R. Adult mesenchymal stem cells and cell-based tissue engineering. Arthritis Res Ther 5 1 (2003) 32-45
    • (2003) Arthritis Res Ther , vol.5 , Issue.1 , pp. 32-45
    • Tuan, R.S.1    Boland, G.2    Tuli, R.3
  • 176
    • 33750289940 scopus 로고    scopus 로고
    • Stemming cartilage degeneration: adultmesenchymal stem cells as a cell source for articular cartilage tissue engineering
    • Tuan R.S. Stemming cartilage degeneration: adultmesenchymal stem cells as a cell source for articular cartilage tissue engineering. Arthritis Rheum 54 10 (2006) 3075-3078
    • (2006) Arthritis Rheum , vol.54 , Issue.10 , pp. 3075-3078
    • Tuan, R.S.1
  • 177
    • 0141426820 scopus 로고    scopus 로고
    • Current state of cartilage tissue engineering
    • Tuli R., Li W.J., and Tuan R.S. Current state of cartilage tissue engineering. Arthritis Res Ther 5 5 (2003) 235-238
    • (2003) Arthritis Res Ther , vol.5 , Issue.5 , pp. 235-238
    • Tuli, R.1    Li, W.J.2    Tuan, R.S.3
  • 178
    • 0142103359 scopus 로고    scopus 로고
    • Transforming growth factorbeta- mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk
    • Tuli R., Tuli S., Nandi S., et al. Transforming growth factorbeta- mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk. J Biol Chem 278 42 (2003) 41227-41236
    • (2003) J Biol Chem , vol.278 , Issue.42 , pp. 41227-41236
    • Tuli, R.1    Tuli, S.2    Nandi, S.3
  • 179
    • 0024338070 scopus 로고
    • Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines
    • Tyler J.A. Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines. Biochem J 260 2 (1989) 543-548
    • (1989) Biochem J , vol.260 , Issue.2 , pp. 543-548
    • Tyler, J.A.1
  • 180
    • 0032513039 scopus 로고    scopus 로고
    • Regulatory activities of the 5′- and 3′-untranslated regions and promoter of the human aggrecan gene
    • Valhmu W.B., Palmer G.D., Dobson J., et al. Regulatory activities of the 5′- and 3′-untranslated regions and promoter of the human aggrecan gene. J Biol Chem 273 11 (1998) 6196-6202
    • (1998) J Biol Chem , vol.273 , Issue.11 , pp. 6196-6202
    • Valhmu, W.B.1    Palmer, G.D.2    Dobson, J.3
  • 181
    • 0032076751 scopus 로고    scopus 로고
    • Differential effects of IGF-1 and TGF beta-2 on the assembly of proteoglycans in pericellular and territorial matrix by cultured bovine articular chondrocytes
    • van Osch G.J., van den Berg W.B., Hunziker E.B., et al. Differential effects of IGF-1 and TGF beta-2 on the assembly of proteoglycans in pericellular and territorial matrix by cultured bovine articular chondrocytes. Osteoarthritis Cartilage 6 3 (1998) 187-195
    • (1998) Osteoarthritis Cartilage , vol.6 , Issue.3 , pp. 187-195
    • van Osch, G.J.1    van den Berg, W.B.2    Hunziker, E.B.3
  • 182
    • 11144240780 scopus 로고    scopus 로고
    • Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair
    • Venkatesan N., Barre L., Benani A., et al. Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair. Proc Natl Acad Sci USA 101 52 (2004) 18087-18092
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.52 , pp. 18087-18092
    • Venkatesan, N.1    Barre, L.2    Benani, A.3
  • 183
    • 0025302084 scopus 로고
    • Differential effects of transforming growth factor-beta and epidermal growth factor on the cell cycle of cultured rabbit articular chondrocytes
    • Vivien D., Galera P., Lebrun E., et al. Differential effects of transforming growth factor-beta and epidermal growth factor on the cell cycle of cultured rabbit articular chondrocytes. J Cell Physiol 143 3 (1990) 534-545
    • (1990) J Cell Physiol , vol.143 , Issue.3 , pp. 534-545
    • Vivien, D.1    Galera, P.2    Lebrun, E.3
  • 184
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • VortkampA, Lee K., Lanske B., et al. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science 273 5275 (1996) 613-622
    • (1996) Science , vol.273 , Issue.5275 , pp. 613-622
    • VortkampA1    Lee, K.2    Lanske, B.3
  • 185
    • 0034852850 scopus 로고    scopus 로고
    • Interaction of growth factors regulating chondrocyte differentiation in the developing embryo
    • Vortkamp A. Interaction of growth factors regulating chondrocyte differentiation in the developing embryo. Osteoarthritis Cartilage 9 Suppl (2001) 109-117
    • (2001) Osteoarthritis Cartilage , vol.9 , Issue.SUPPL , pp. 109-117
    • Vortkamp, A.1
  • 186
    • 0030659459 scopus 로고    scopus 로고
    • Hepatocyte growth factor facilitates cartilage repair. Full thickness articular cartilage defect studied in rabbit knees
    • Wakitani S., Imoto K., Kimura T., et al. Hepatocyte growth factor facilitates cartilage repair. Full thickness articular cartilage defect studied in rabbit knees. Acta Orthop Scand 68 5 (1997) 474-480
    • (1997) Acta Orthop Scand , vol.68 , Issue.5 , pp. 474-480
    • Wakitani, S.1    Imoto, K.2    Kimura, T.3
  • 187
    • 9344222791 scopus 로고    scopus 로고
    • Autologous bone marrow stromal cell transplantation for repair of fullthickness articular cartilage defects in human patellae: two case reports
    • Wakitani S., Mitsuoka T., Nakamura N., et al. Autologous bone marrow stromal cell transplantation for repair of fullthickness articular cartilage defects in human patellae: two case reports. Cell Transplant 13 5 (2004) 595-600
    • (2004) Cell Transplant , vol.13 , Issue.5 , pp. 595-600
    • Wakitani, S.1    Mitsuoka, T.2    Nakamura, N.3
  • 188
    • 0034843171 scopus 로고    scopus 로고
    • Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose
    • Weisser J., Rahfoth B., Timmermann A., et al. Role of growth factors in rabbit articular cartilage repair by chondrocytes in agarose. Osteoarthritis Cartilage 9 Suppl (2001) 48-54
    • (2001) Osteoarthritis Cartilage , vol.9 , Issue.SUPPL , pp. 48-54
    • Weisser, J.1    Rahfoth, B.2    Timmermann, A.3
  • 189
    • 0033559906 scopus 로고    scopus 로고
    • Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws
    • Whalen J.D., Lechman E.L., Carlos C.A., et al. Adenoviral transfer of the viral IL-10 gene periarticularly to mouse paws suppresses development of collagen-induced arthritis in both injected and uninjected paws. J Immunol 162 6 (1999) 3625-3632
    • (1999) J Immunol , vol.162 , Issue.6 , pp. 3625-3632
    • Whalen, J.D.1    Lechman, E.L.2    Carlos, C.A.3
  • 190
    • 0034927587 scopus 로고    scopus 로고
    • Chondrocytic differentiation of mesenchymal stem cells sequentially exposed to transforming growth factor-beta1 in monolayer and insulin-like growth factor-I in a three-dimensional matrix
    • Worster A.A., Brower-Toland B.D., Fortier L.A., et al. Chondrocytic differentiation of mesenchymal stem cells sequentially exposed to transforming growth factor-beta1 in monolayer and insulin-like growth factor-I in a three-dimensional matrix. J Orthop Res 19 4 (2001) 738-749
    • (2001) J Orthop Res , vol.19 , Issue.4 , pp. 738-749
    • Worster, A.A.1    Brower-Toland, B.D.2    Fortier, L.A.3
  • 191
    • 0032922670 scopus 로고    scopus 로고
    • Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9
    • Xie W.F., Zhang X., Sakano S., et al. Trans-activation of the mouse cartilage-derived retinoic acid-sensitive protein gene by Sox9. J Bone Miner Res 14 5 (1999) 757-763
    • (1999) J Bone Miner Res , vol.14 , Issue.5 , pp. 757-763
    • Xie, W.F.1    Zhang, X.2    Sakano, S.3
  • 192
    • 0034181184 scopus 로고    scopus 로고
    • Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining
    • Yao Q., Glorioso J.C., Evans C.H., et al. Adenoviral mediated delivery of FAS ligand to arthritic joints causes extensive apoptosis in the synovial lining. J Gene Med 2 3 (2000) 210-219
    • (2000) J Gene Med , vol.2 , Issue.3 , pp. 210-219
    • Yao, Q.1    Glorioso, J.C.2    Evans, C.H.3
  • 193
    • 0037670222 scopus 로고    scopus 로고
    • Intra-articular adenoviralmediated gene transfer of trail induces apoptosis of arthritic rabbit synovium
    • Yao Q., Wang S., Gambotto A., et al. Intra-articular adenoviralmediated gene transfer of trail induces apoptosis of arthritic rabbit synovium. Gene Ther 10 12 (2003) 1055-1060
    • (2003) Gene Ther , vol.10 , Issue.12 , pp. 1055-1060
    • Yao, Q.1    Wang, S.2    Gambotto, A.3
  • 194
    • 12344321351 scopus 로고    scopus 로고
    • Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector
    • Yokoo N., Saito T., Uesugi M., et al. Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector. Arthritis Rheum 52 1 (2005) 164-170
    • (2005) Arthritis Rheum , vol.52 , Issue.1 , pp. 164-170
    • Yokoo, N.1    Saito, T.2    Uesugi, M.3
  • 195
    • 0032425950 scopus 로고    scopus 로고
    • The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells
    • Yoo J.U., Barthel T.S., Nishimura K., et al. The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg Am 80 12 (1998) 1745-1757
    • (1998) J Bone Joint Surg Am , vol.80 , Issue.12 , pp. 1745-1757
    • Yoo, J.U.1    Barthel, T.S.2    Nishimura, K.3
  • 196
    • 0033770532 scopus 로고    scopus 로고
    • Chondrogenitor cells and gene therapy
    • Yoo J.U., Mandell I., Angele P., et al. Chondrogenitor cells and gene therapy. Clin Orthop 379 Suppl (2000) S164-S170
    • (2000) Clin Orthop , vol.379 , Issue.SUPPL
    • Yoo, J.U.1    Mandell, I.2    Angele, P.3
  • 197
    • 0032511091 scopus 로고    scopus 로고
    • Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo
    • Zhou G., Lefebvre V., Zhang Z., et al. Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo. J Biol Chem 273 24 (1998) 14989-14997
    • (1998) J Biol Chem , vol.273 , Issue.24 , pp. 14989-14997
    • Zhou, G.1    Lefebvre, V.2    Zhang, Z.3
  • 198
    • 0035067539 scopus 로고    scopus 로고
    • Multilineage cells from human adipose tissue: implications for cell-based therapies
    • Zuk P.A., Zhu M., Mizuno H., et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7 2 (2001) 211-228
    • (2001) Tissue Eng , vol.7 , Issue.2 , pp. 211-228
    • Zuk, P.A.1    Zhu, M.2    Mizuno, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.