The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells

Journal of Bone and Joint Surgery

Volumn 80, Issue 12, 1998, Pages 1745-1757

  Yoo, Jung U ^a,b   Barthel, Traci S ^a,b   Nishimura, Keita ^a,b   Solchaga, Luis ^a,b   Caplan, Arnold I ^a,b   Goldberg, Victor M ^a,b   Johnstone, Brian ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; BIGLYCAN; CHONDROITIN 4 SULFATE; COLLAGEN TYPE 1; DECORIN; KERATAN SULFATE; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; ARTICULAR CARTILAGE; CELL DIFFERENTIATION; CHONDROGENESIS; FRACTURE HEALING; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MESENCHYME CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REPRODUCIBILITY;

EID: 0032425950     PISSN: 00219355     EISSN: None     Source Type: Journal    
DOI: 10.2106/00004623-199812000-00004     Document Type: Article

References (47)

1. Adams, S. L.; Boettinger, D.; Focht, R. J.; Holtzer, H.; and Pacifici, M.: Rapid induction of type X collagen gene expression in cultured chick vertebral chondrocytes. Exper. Cell Res., 193:190-197, 1991.
2. Ahrens, P. B.; Solursh, M.; and Reiters, K. S.: Stage-related capacity for limb chondrogenesis in cell culture. Devel. Biol., 60:69-82, 1977.
3. Asahina, I.; Sampath, T. K.; Nishimura, I.; and Hauschka, P. V.: Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria.J. Cell Biol., 123:921-933, 1993.
4. Ashton, B. A.; Allen, T. D.; Hewlett, C. R.; Eaglesom, C. C.; Hattori, A.; and Owen, M.: Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo. Clin. Orthop., 151:294-307, 1980.
5. Ballock, R. T., and Reddi, A. H.: Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium.J Cell Biol., 126:1311-1318, 1994.
6. Brand, R. A.: Fracture healing. In The Scientific Basis of Orthopaedics, pp. 289-311. Edited by J. A. Albright and R. A. Brand. New York, Appleton-Century-Crofts, 1979.
7. Bruder, S. P.; Jaiswal, N.; and Haynesworth, S. E.: Growth kinetics, self-renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation. J. Cell. Biochem., 64:278-294, 1997.
8. Buckwalter, J. A.; Rosenberg, L. C.; and Munziker, E. B.: Articular cartilage: composition, structure, response to injury, and methods of facilitating repair. In Articular Cartilage and Knee Joint Function: Basic Science and Arthroscopy, pp. 19-56. Edited by J. W. Ewing. New York, Raven Press, 1990.
9. Calandruccio, R. A., and Gilmer, W. S., Jr.: Proliferation, regeneration, and repair of articular cartilage of immature animals. J. Bone and Joint Surg., 44-A: 431-455, April 1962.
10. Cancedda, R.; Dcscalzi Cancedda, E; and Castagnola, P.: Chondrocyte differentiation. Internat. Rev. Cytol., 159:265-358, 1995.
11. Caplan, A. I., and Stoolmiller, A. C.: Control of chondrogenic expression in mesodermal cells of embryonic chick limb. Proc. Nat. Acad. Sci., 70:1713-1717, 1973.
12. Carrino, D. A.; Arias, J. L.; and Caplan, A. I.: A spectrophotometric modification of a sensitive densitometric safranin O assay for glycosaminoglycans. Biochem. Internat., 24:485-495, 1991.
13. Chu, C. R.; Dounchis, J. S.; Yoshioka, M.; Sah, R. L.; Coutts, R. D.; and Amiel, D.: Osteochondral repair using perichondrial cells. A 1-year study in rabbits. Clin. Orthop., 340:220-229, 1997.
14. Coutts, R. D.; Woo, S. L.; Amiel, D.; von Schroeder, H. P.; and Kwan, M. K.: Rib perichondrial autografts in full-thickness articular cartilage defects in rabbits. Clin. Orthop., 275:263-273, 1992.
15. Denker, A. E.; Nicoll, S. B.; and Tuan, R. S.: Formation of cartilage-like spheroids by micromass cultures of murine C3H10T1/2 cells upon treatment with transforming growth factor-beta 1. Differentiation, 59:25-34, 1995.
16. Fell, H. B.: The histiogenesis of cartilage and bone in the long bones of the embryonic fowl. J. Morphol., 40:417-460, 1925.
17. Friedenstein, A. J.: Precursor cells of mechanocytes. Internat. Rev. Cytol., 47:327-359, 1976.
18. Goshima, J.; Goldberg, V. M.; and Caplan, A. I.: The osteogenic potential of culture-expanded rat marrow mesenchymal cells assayed in vivo in calcium phosphate ceramic blocks. Clin. Orthop., 262:298-311, 1991.
19. Grande, D. A.; Southerland, B. S.; and Manji, R.: Repair of articular defects using mesenchymal stem cells. Tissue Eng., 1:345-352, 1995.
20. Grigoriadis, A. E.; Heersche, J. N.; and Aubin, J. E.: Continuously growing bipotential and monopotential myogenic, adipogenic, and chondrogenic subclones isolated from the multipotential RCJ 3.1 clonal cell line. Devel. Biol, 142:313-318, 1990.
21. Haynesworth, S. E.; Goshima, J.; Goldberg, V. M.; and Caplan, A. I.: Characterization of cells with osteogenic potential from human marrow. Bone, 13:81-88, 1992.
22. Hunziker, E. B., and Rosenberg, L. C.: Repair of partial thickness defects in articular cartilage: cell recruitment from the synovial membrane. J. Bone and Joint Surg., 78-A: 721-733, May 1996.
23. Johnstone, B.; Hering, T. M.; Caplan, A. I.; Goldberg, V. M.; and Yoo, J. U.: In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exper. Cell Res., 238:265-272, 1998.
24. Kadiyala, S.; Jaiswal, N.; and Bruder, S. P.: Culture-expanded, bone marrow-derived mesenchymal stem cells regenerate a critical-sized segmental bone defect. Tissue Eng., 3:173-185, 1997.
25. Kreder, H. J.; Moran, M.; Keeley, F. W.; and Salter, R. B.: Biologic resurfacing of a major joint defect with cryopreserved allogeneic periosteum under the influence of continuous passive motion in a rabbit model. Clin. Orthop., 300:288-296, 1994.
26. Lennon, D. P.; Haynesworth, S. E.; Bruder, S. P.; Jaiswal, N.; and Caplan, A. I.: Human and animal mesenchymal progenitor cells from bone marrow: identification of serum for optimal selection and proliferation. In Vitro Cell, and Devel. Biol., 32:602-611, 1996.
27. Linkhart, T. A.; Mohan, S.; and Baylink, D. J.: Growth factors for bone growth and repair: IGF, TGF beta and BMP. Bone, 19 (Supplement 1): 1S-12S, 1996.
28. McKibbin, B.: The biology of fracture healing in long bones. J. Bone and Joint Surg., 60-B(2): 150-162, 1978.
29. Maniatopoulos, C.; Sodek, J.; and Melcher, A. H.: Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell and Tissue Res., 254:317-330, 1988.
30. Mankin, H. J.: The reaction of articular cartilage to injury and osteoarthritis (first of two parts). New England J. Med., 291:1285-1292, 1974.
31. Meachim, G., and Roberts, C.: Repair of the joint surface from subarticular tissue in the rabbit knee. J. Anat., 109:317-327, 1971.
32. Nakahara, H.; Bruder, S. P.; Haynesworth, S. E.; Holecek, J. J.; Baber, M. A.; Goldberg, V. M.; and Caplan, A. I.: Bone and cartilage formation in diffusion chambers by subcultured cells derived from the periosteum. Bone, 11:181-188, 1990.
33. Nemeth, C. C.; Bolander, M. E.; and Martin, G. R.: Growth factors and their role in wound and fracture healing. In Growth Factors and Other Aspects of Wound Healing: Biological and Clinical Implications: Proceedings of the Second International Symposium on Tissue Repair, pp. 1-17. Edited by A. Barbul, E. Pines, M. Caldwell, and T. K. Hunt. New York, Wiley-Liss, 1988.
34. Niedzwiedzki, T.; Dabrowski, Z.; Miszta, H.; and Pawlikowski, M.: Bone healing after bone marrow stromal cell transplantation to the bone defect. Biomaterials, 14:115-121, 1993.
35. Osdoby, P., and Caplan, A. I.: Osteogenesis in cultures of limb mesenchymal cells. Devel. Biol., 73:84-102, 1979.
36. Otsuka, Y.; Mizuta, H.; Takagi, K.; Iyama, K.; Yoshitake, Y.; Nishikawa, K.; Suzuki, E; and Hiraki, Y.: Requirement of fibroblast growth factor signalling for regeneration of epiphyseal morphology in rabbit full-thickness defects of articular cartilage. Devel. Growth and Diff., 39:143-156, 1997.
37. Owen, M.: The origin of bone cells in the postnatal organism. Arthrit. and Rheumat., 23:1073-1080, 1980.
38. Paley, D.; Young, M. C.; Wiley, A. M.; Fornasier, V. L.; and Jackson, R. W.: Percutaneous bone marrow grafting of fractures and bone defects. An experimental study in rabbits. Clin. Orthop., 208:300-312, 1986.
39. Sellers, R. S.; Peluso, D.; and Morris, E. A.: The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage. J. Bone and Joint Surg., 79-A: 1452-1463, Oct. 1997.
40. Shapiro, F.; Koide, S.; and Glimcher, M. J.: Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J. Bone and Joint Surg., 75-A: 532-553, April 1993.
41. Solursh, M.: Formation of cartilage tissue in vitro.J. Cell. Biochem., 45:258-260, 1991.
42. Tachetti, C.; Quarto, R.; Nitsch, L.; Hartmann, D. J.; and Cancedda, R.: In vitro morphogenesis of chick embryo hypertrophic cartilage. J. Cell Biol., 105:999-1006, 1987.
43. Tavella, S.; Rafto, P.; Tacchetti, C.; Cancedda, R.; and Castagnola, P.: N-CAM and N-cadherin expression during in vitro chondrogenesis. Exper. Cell Res., 215:354-362, 1994.
44. Topping, R. E.; Bolander, M. E.; and Balian, G.: Type X collagen in fracture callus and the effects of experimental diabetes. Clin. Orthop., 308:220-228, 1994.
45. Wakitani, S.; Goto, T.; Pineda, S. J.; Young, R. G.; Mansour, J. M.; Caplan, A. I.; and Goldberg, V. M.: Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage. J. Bone and Joint Surg., 76-A: 579-592, April 1994.
46. Werntz, J. R.; Lane, J. M.; Burstein, A. H.; Justin, R.; Klein, R.; and Tomin, E.: Qualitative and quantitative analysis of orthotopic bone regeneration by marrow. J. Orthop. Res., 14:85-93, 1996.
47. Zimmermann, B., and Cristea, R.: Dexamethasone induces chondrogenesis in organoid culture of cell mixtures from mouse embryos. Anat. and Embryo!., 187:67-73, 1993.