A 47-bp sequence of the first intron of the mouse Proα1(II) collagen gene is sufficient to direct chondrocyte expression

Annals of the New York Academy of Sciences

Volumn 785, Issue , 1996, Pages 284-287

  Lefebvre, Véronique ^a   Mukhopadhyay, Krish ^a   Zhou, Guang ^a   Garofalo, Silvio ^a,c   Smith, Chad ^a   Eberspaecher, Heidi ^a   Kimura, James H ^b   De Crombrugghe, Benoit ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b HENRY FORD HOSPITAL   (United States)

^c Shriners Hospital for Crippled   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; PROCOLLAGEN;

ANIMAL CELL; CARTILAGE CELL; CHONDROGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; INTRON; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION;

EID: 0029778219     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb56285.x     Document Type: Conference Paper

References (4)

1. MUKHOPADHYAY, K., V. LEFEBVRE, G. ZHOU, S. GAROFALO, J. H. KIMURA & B. DE CROMBRUGGHE. 1995. Use of a new rat chondrosarcoma cell line to delineate a 119-bp chondrocyte-specific enhancer element and to define active promoter segments in the mouse proα1(II) collagen gene. J. Biol. Chem. 270: 27711-27719.
2. HORTON, W., T. MIYASHITA, K. KOHNO, J. R. HASSELL & Y. YAMADA. 1987. Identification of a phenotype-specific enhancer in the first intron of the rat collagen II gene. Proc. Natl. Acad. Sci. U.S.A. 84: 8864-8868.
3. ZHOU, G., S. GAROFALO, K. MUKHOPADHYAY, V. LEFEBVRE, C. SMITH, H. EBERSPAECHER & B. DE CROMBRUGGHE. 1995. A 182-bp fragment of the mouse proα1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice. J. Cell Sci. 108: 3677-3684.
4. LEFEBVRE, V., G. ZHOU, K. MUKHOPADHYAY, X. ZHOU, H. EBERSPAECHER, C. SMITH, Z. ZHANG & B. DE CROMBRUGGHE. An 18-bp sequence of the mouse proα1(II) collagen gene is sufficient to direct cartilage expression and binds nuclear proteins selectively expressed in chondrocytes. In preparation.