Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms

Journal of Biological Chemistry

Volumn 279, Issue 25, 2004, Pages 26597-26604

  Hwang, Sang Gu ^a   Ryu, Je Hwang ^a   Kim, Il Chul ^a   Jho, Eek Hoon ^b   Jung, Ho Chul ^c   Kim, Kwonseop ^c   Kim, Song Ja ^d   Chun, Jang Soo ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b University of Seoul   (South Korea)

^c Chonnam National University   (South Korea)

^d Kongju National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CARTILAGE; CELLS; DIFFERENTIAL EQUATIONS; SIGNALING;

APOPTOSIS; CHONDROCYTES; PHENOTYPE;

ENZYME INHIBITION;

BETA CATENIN; CYTOKINE; INTERLEUKIN 1BETA; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; WNT PROTEIN; WNT5A PROTEIN; WNT7A PROTEIN;

ADULT; AGED; ANIMAL CELL; APOPTOSIS; ARTHRITIS; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL ACTIVATION; CELL DIFFERENTIATION; CELL SURVIVAL; CHONDROGENESIS; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RABBIT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AGED; ANIMALS; APOPTOSIS; BETA CATENIN; BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CASPASE 3; CASPASES; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; CULTURE MEDIA, CONDITIONED; CYTOSKELETAL PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; LUCIFERASES; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; NITRIC OXIDE; PHENOTYPE; PRECIPITIN TESTS; PROTEIN BINDING; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 2942715076     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401401200     Document Type: Article

References (41)

1. DeLise, A. M., Fisher, L., and Tuan, R. S. (2000) Osteoarthritis Cartilage 8, 309-334
2. Oberlender, S. A., and Tuan, R. S. (1994) Development 120, 177-187
3. Tufan, A. C., and Tuan, R. S. (2001) FASEB J. 15, 1436-1438
4. Kengaku, M., Capdevila, J., Rodriguez-Esteban, C., De La Pena, J., Johnson, R. L., and Belmonte, J. C. I. (1998) Science 280, 1274-1277
5. Wodarz, A., and Nusse, R. (1998) Annu. Rev. Cell Dev. Biol. 14, 59-88
6. Hartmann, C., and Tabin, C. J. (2000) Development 127, 3141-3159
7. Church, V., Nohno, T., Linker, C., Marcelle, C., and Francis-West, P. (2002) J. Cell Sci. 115, 4809-48018
8. Rudnicki, J. A., and Brown, A. M. (1997) Dev. Biol. 185, 104-118
9. Tufan, A. C., Daumer, K. M., DeLise, A. M., and Tuan R. S. (2002) Exp. Cell Res. 273, 197-203
10. Ben-Ze'ev, A., and Geiger, B. (1998) Curr. Opin. Cell Biol. 10, 629-639
11. Willert, K., and Nusse, R. (1998) Curr. Opin. Genet. Dev. 8, 95-102
12. Sandell, L. J., and Aigner, T. (2001) Arthritis Res. 3, 107-113
13. Ghosh, P., and Smith, M. (2002) Biogerontology 3, 85-88
14. Amin, A. R., and Abramson, S. B. (1998) Curr. Opin. Rheumatol. 10, 263-268
15. Abramson, S. B., Attur, M., Amin, A. R., and Clancy, R. (2001) Curr. Rheumatol. Rep. 3, 535-541
16. Kim, S.-J., Ju, J.-W., Oh, C.-D. Yoon, Y.-M., Song, W.-K., Kim, J.-H., Yoo, Y.-J., Bang, O.-S., Kang, S.-S., and Chun, J.-S. (2002) J. Biol. Chem. 277, 1332-1339
17. Kim, S.-J., Kim, H.-G., Oh, C.-D., Hwang, S.-G., Song, W.-K., Yoo, Y.-J., Kang, S.-S., and Chun, J.-S. (2002) J. Biol. Chem. 277, 30375-30381
18. Kim, S.-J., Hwang, S.-G., Shin, D.-Y., Kang, S.-S., and Chun, J.-S. (2002) J. Biol. Chem. 277, 33501-33508
19. Kim, S.-J., and Chun, J.-S. (2003) Biochem. Biophys. Res. Commun. 303, 206-211
20. Oh, C.-D., and Chun, J.-S. (2003) J. Biol. Chem. 278, 36563-36571
21. Yoon, J.-B., Kim, S.-J., Hwang, S.-G., Chang, S., Kang, S.-S., and Chun, J.-S. (2003) J. Biol. Chem. 278, 15319-15325
22. Sen, M., Lauterbach, K., El-Gabalawy, H., Firestein, G. S., Corr, M., and Carson, D. A. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 2791-2796
23. James, I. E., Kumar, S., Barnes, M. R., Gress, C. J., Hand, A. T., Dodds, R. A., Connor, J. R., Bradley, B. R., Campbell, D. A., Grabill, S. E., Williams, K., Blake, S. M., Gowen, M., and Lark, M. W. (2000) Osteoarthritis Cartilage 8, 452-463
24. Ryu, J.-H., Kim, S.-J., Kim, S.-H., Oh, C.-D., Hwang, S.-G., Chun, C.-H., Oh, S.-H., Seong, J.-K., Huh, T.-L., and Chun, J.-S. (2002) Development 129, 5541-5550
25. Chen, S., Guttridge, D. C., You, Z., Zhang, Z., Fribley, A., Mayo, M. W., Kitajewski, J., and Wang, C. Y. (2001) J. Cell Biol. 152, 87-96
26. Longo, K. A., Kennell, J. A., Ochocinska, M. J., Ross, S. E., Wright, W. S., and MacDougald, O. A. (2002) J. Biol. Chem. 277, 38239-38244
27. Altman, R., Asch, E., Bloch, D., Bole, G., Borenstein, D., Brandt, K., Christy, W., Cooke, T. D., Greenwald, R., and Hochberg, M. (1986) Arthritis Rheum. 29, 1039-1049
28. Yoon, Y.-M., Kim, S.-J., Oh, C.-D., Ju, J.-W., Song, W.-K., Yoo, Y.-J., Huh, T.-L., and Chun, J.-S. (2002). J. Biol. Chem. 277, 8412-8420
29. Kitagaki, J., Iwamoto, M., Liu, J. G., Tamamura, Y., Pacifci, M., and Enomoto-Iwamoto, M. (2003) Osteoarthritis Cartilage 11, 36-43
30. Lyu, J., Costantini, F., Jho, E.-H., and Joo, C.-K. (2003) J. Biol. Chem. 278, 13487-13495
31. Korinek V., Barker, N., Morin, P. J., van Wichen, D., de Weger, R., Kinzler, K. W., Vogelstein, B., and Clevers, H. (1997) Science 275, 1784-1787
32. Dealy, C. N., Roth, A., Ferrari, D., Brown, A. M., and Kosher, R. A. (1993) Mech. Dev. 43, 175-186
33. Stanton, L. A., Sabari, S., Sampaio, A. V., Underhill, T. M., and Beier, F. (2004) Biochem. J. 378, 53-62
34. Bergwitz, C., Wendlandt, T., Kispert, A., and Brabant, G. (2001) Biochim. Biophys. Acta 1538, 129-140
35. Giese, K., Kingsley, C., Kirshner, J. R., and Grosschedl, R. (1995) Genes Dev. 9, 995-1008
36. Giese, K., Amsterdam, A., and Grosschedl, R. (1991) Genes Dev. 5, 2567-2578
37. Piepenburg, O., Vorbruggen, G., and Jackle, H. (2000) Mol. Cell 6, 203-209
38. Yang, X., van Beest, M., Clevers, H., Jones, T., Hursh, D. A., and Mortin, M. A. (2000) Development 127, 3695-3702
39. Lisovsky, M., Itoh, K., and Sokol, S. Y. (2002) Curr. Biol. 12, 53-58
40. Orford, K., Orford, C. C., and Byers, S. W. (1999) J. Cell. Biol. 146, 855-868
41. Ioannidis, V., Beermann, F., Clevers, H., and Held, W. (2001) Nat. Immunol. 2, 691-697