NK cells and their receptors

Reproductive BioMedicine Online

Volumn 16, Issue 2, 2008, Pages 173-191

  Yokoyama, Wayne M ^a   Riley, Joan K ^b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activation; Inhibition; Major histocompatibility complex; NK cell receptors; Selective expression; Uterus

Indexed keywords

C TYPE LECTIN RELATED PROTEIN; CARCINOEMBRYONIC ANTIGEN; CD16 ANTIGEN; CD161 ANTIGEN; CD3 ANTIGEN; CD56 ANTIGEN; CD94 ANTIGEN; CELL MARKER; CELL RECEPTOR; FC RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 2 RECEPTOR BETA; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; LECTIN; LIGAND; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE PROTEIN; NATURAL CYTOTOXICITY RECEPTOR; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2A; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN 2B4; PROTEIN INHIBITOR; RECEPTOR LY49; UNCLASSIFIED DRUG;

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; AUTOIMMUNITY; CELL ACTIVATION; CELL ACTIVITY; CELL JUNCTION; CONFERENCE PAPER; CYTOKINE PRODUCTION; CYTOTOXICITY; ENDOMETRIUM CELL; EXOCYTOSIS; GENE EXPRESSION; HUMAN; INNATE IMMUNITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR RECOGNITION; NATURAL KILLER CELL; NONHUMAN; PREGNANCY OUTCOME; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; UTERUS;

EID: 39749103075     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)60573-1     Document Type: Conference Paper

References (366)

1. Aldemir H, Prod'homme V, Dumaurier MJ et al. 2005 Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor. Journal of Immunology 175, 7791-7795.
2. Aldrich CJ, DeCloux A, Woods AS et al. 1994 Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen. Cell 79, 649-658.
3. Allan DS, Colonna M, Lamer LL et al. 1999 Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells. Journal of Experimental Medicine 189, 1149-1156.
4. Allcock RJ, Barrow AD, Forbes S et al. 2003 The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. European Journal of Immunology 33, 567-577.
5. Anderson P, Caligiuri M, Ritz J et al. 1989 CD3-negative natural killer cells express zeta TCR as part of a novel molecular complex. Nature 341, 159-162.
6. Anegon I, Cuturi MC, Trinchieri G et al. 1988 Interaction of Fc receptor (CD16) ligands induces transcription of interleukin 2 receptor (CD25) and lymphokine genes and expression of their products in human natural killer cells. Journal of Experimental Medicine 167, 452-472.
7. Arase H, Mocarski ES, Campbell AE et al. 2002 Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 296, 1323-1326.
8. Arase H, Saito T, Phillips JH et al. 2001 Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). Journal of Immunology 167, 1141-1144.
9. + T cells. Journal of Experimental Medicine 186, 1957-1963.
10. Arase H, Arase N, Saito T 1995 Fas-mediated cytotoxicity by freshly isolated natural killer cells. Journal of Experimental Medicine 181, 1235-1238.
11. Ashkar AA, Croy BA 2001 Functions of uterine natural killer cells are mediated by interferon gamma production during murine pregnancy. Seminars in Immunology 13, 235-241.
12. Ashkar AA, Croy BA 1999 Interferon-gamma contributes to the normalcy of murine pregnancy. Biology of Reproduction 61, 493-502.
13. Ashkar AA, Di Santo JP, Croy BA 2000 Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy. Journal of Experimental Medicine 192, 259-270.
14. Avril T, Floyd H, Lopez F et al. 2004 The membrane-proximal immunoreceptor tyrosine-based inhibitory motif is critical for the inhibitory signaling mediated by Siglecs-7 and -9, CD33-related Siglecs expressed on human monocytes and NK cells. Journal of Immunology 173, 6841-6849.
15. Bacon L, Eagle RA, Meyer M et al. 2004 Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D. Journal of Immunology 173, 1078-1084.
16. Bakker AB, Hoek RM, Cerwenka A et al. 2000 DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming. Immunity 13, 345-353.
17. Banham AH, Colonna M, Cella M et al. 1999 Identification of the CD85 antigen as ILT2, an inhibitory MHC class I receptor of the immunoglobulin superfamily. Journal of Leukocyte Biology 65, 841-845.
18. Barbosa MD, Nguyen QA, Tchernev VT et al. 1996 Identification of the homologous beige and Chediak-Higashi syndrome genes. Nature 382, 262-265.
19. Barclay AN, Brown MH, Law SKA et al. 1997 The Leucocyte Antigen Facts book, 2nd edn. Academic Press, San Diego.
20. Barten R, Torkar M, Haude A et al. 2001 Divergent and convergent evolution of NK-cell receptors. Trends in Immunology 22, 52-57.
21. Bashirova AA, Martin MP, McVicar DW et al. 2006 The killer immunoglobulin-like receptor gene cluster: tuning the genome for defense. Annual Review of Genomics and Human Genetics 7, 277-300.
22. Bauer S, Groh V, Wu J et al. 1999 Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285, 727-729.
23. Bendelac A, Rivera MN, Park SH et al. 1997 Mouse CD1-specific NK1 T cells: development, specificity, and function. Annual Review of Immunology 15, 535-562.
24. Biassoni R, Cantom C, Falco M et al. 1996 The human leukocyte antigen (HLA)-C-specific 'activatory' or 'inhibitory' natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions. Journal of Experimental Medicine 183, 645-650.
25. Biron CA 2001 Interferons alpha and beta as immune regulators - a new look. Immunity 14, 661-664.
26. Boles KS, Barchet W, Diacovo T et al. 2005 The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8+ T-cell responses through the cell-surface receptor CRTAM. Blood 106, 779-786.
27. Boles KS, Batten R, Kumaresan PR et al. 1999 Cloning of a new lectin-like receptor expressed on human NK cells. Immunogenetics 50, 1-7.
28. Borrego F, Ulbrecht M, Weiss EH et al. 1998 Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. Journal of Experimental Medicine 187, 813-818.
29. Boyington JC, Motyka SA, Schuck P et al. 2000 Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature 405, 537-543.
30. Braud VM, Allen DSJ, O'Callaghan CA et al. 1998 HLA-E binds to natural-killer-cell receptors CD94/NKG2A, B and C. Nature 391, 795-799.
31. Brennan J, Lemieux S, Freeman JD et al. 1996 Heterogeneity among Ly-49C natural killer (NK) cells - characterization of highly related receptors with differing functions and expression patterns. Journal of Experimental Medicine 184, 2085-2090.
32. Brennan J, Mager D, Jefferies W et al. 1994 Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. Journal of Experimental Medicine 180, 2287-2295.
33. Brown MG, Dokun AO, Heusel JW et al. 2001 Vital involvement of a natural killer cell activation receptor in resistance to viral infection. Science 292, 934-937.
34. Brown MH, Boles K, Anton van der Merwe P et al. 1998 2B4, the natural killer and T cell immunoglobulin superfamily surface protein, is a ligand for CD48. Journal of Experimental Medicine 188, 2083-2090.
35. Bui JD, Carayannopoulos LN, Lanier LL et al. 2006 IFN-dependent down-regulation of the NKG2D ligand H60 on tumors. Journal of Immunology 176, 905-913.
36. Cambiaggi A, Verthuy C, Naquet P et al. 1997 Natural killer cell acceptance of H-2 mismatch bone marrow grafts in transgenic mice expressing HLA-Cw3 specific killer cell inhibitory receptor. Proceedings of the National Academy of Sciences of the USA 94, 8088-8092.
37. Cantoni C, Bottino C, Vitale M et al. 1999 NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily. Journal of Experimental Medicine 189, 787-796.
38. Cantoni C, Verdiani S, Falco M et al. 1998 P49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily. European Journal of Immunology 28, 1980-1990.
39. Carayannopoulos L, Naidenko O, Fremont D et al. 2002a Cutting edge: Murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D. Journal of Immunology 169, 4079-4083.
40. Carayannopoulos LN, Naidenko OV, Kinder J et al. 2002b Ligands for murine NKG2D display heterogeneous binding behavior. European Journal of Immunology 32, 597-605.
41. Carlyle JR, Mesci A, Ljutic B et al. 2006 Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cells. Journal of Immunology 176, 7511-7524.
42. Carlyle JR, Jamieson AM, Gasser S et al. 2004 Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proceedings of the National Academy of Sciences of the United States of America 101, 3527-3532.
43. Carlyle JR, Martin A, Mehra A et al. 1999 Mouse NKR-P1B, a novel NK1.1 antigen with inhibitory function. Journal of Immunology 162, 5917-5923.
44. Carretero M, Cantoni C, Bellon T et al. 1997 The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules. European Journal of Immunology 27, 563-567.
45. Castells MC, Klickstein LB, Hassani K et al. 2001 gp49B1-alpha(v)beta3 interaction inhibits antigen-induced mast cell activation. Nature Immunology 2, 436-442.
46. Cella M, Longo A, Ferrara GB et al. 1994 NK3-specific natural killer cells are selectively inhibited by Bw4-positive HLA alleles with isoleucine 80. Journal of Experimental Medicine 180, 1235-1242.
47. Cerwenka A, Baron JL, Lanier LL 2001 Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo. Proceedings of the National Academy of Sciences of the USA 98, 11521-11526.
48. Cerwenka A, Bakker ABH, McClanahan T et al. 2000 Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12, 721-727.
49. Chambers WH, Vujanovic NL, DeLeo AB et al. 1989 Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. Journal of Experimental Medicine 169, 1373-1389.
50. Chan PY, Takei F 1989 Molecular cloning and characterization of a novel murine T cell surface antigen, YE1/48. Journal of Immunology 142, 1727-1736.
51. Chang C, Rodriguez A, Carretero M et al. 1995 Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. European Journal of Immunology 25, 2433-2437.
52. Chao KH, Wu MY, Chen CD et al. 1999 The expression of killer cell inhibitory receptors on natural killer cells and activation status of CD4+ and CD8+ T cells in the decidua of normal and abnormal early pregnancies. Human Immunology 60, 791-797.
53. Chapman TL, Heikeman AP, Bjorkman PJ 1999 The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18. Immunity 11, 603-613.
54. Chumbley G, King A, Holmes N et al. 1993 In situ hybridization and northern blot demonstration of HLA-G mRNA in human trophoblast populations by locus-specific oligonucleotide. Human Immunology 37, 17-22.
55. Clark R, Griffiths GM 2003 Lytic granules, secretory lysosomes and disease. Current Opinion in Immunology 15, 516-521.
56. Colonna M 2006 Cytolytic responses: cadherins put out the fire. Journal of Experimental Medicine 203, 261-264.
57. Colonna M 1997 Specificity and function of immunoglobulin superfamily NK cell inhibitory and stimulatory receptors. Immunological Reviews 155, 127-133.
58. Colonna M, Samaridis J 1995 Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268, 367-368.
59. Colonna M, Navarro F, Bellon T et al. 1997 A common inhibitory receptor for MHC class I molecules on human lymphoid and myelomonocytic cells. Journal of Experimental Medicine 186, 1809-1818.
60. Colonna M, Borsellino G, Falco M et al. 1993 HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cells. Proceedings of the National Academy of Sciences of the USA 90, 12000-12004.
61. Cooper MA, Bush JE, Fehniger TA et al. 2002 In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells. Blood 100, 3633-3638.
62. Cooper MA, Fehniger TA, Caligiuri MA 2001 The biology of human natural killer-cell subsets. Trends in Immunology 22, 633-640.
63. Corral L, Hanke T, Vance RE et al. 2000 NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules. European Journal of Immunology 30, 920-930.
64. Correa I, Raulet DH 1995 Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells. Immunity 2, 61-71.
65. Correa I, Corral L, Raulet DH 1994 Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells. European Journal of Immunology 24, 1323-1331.
66. Cosman D, Mullberg J, Sutherland CL et a l. 2001 ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 14, 123-133.
67. Cosman D, Fanger N, Borges L et al. 1997 A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 7, 273-282.
68. Croy BA, van den Heuvel MJ, Borzychowski AM et al. 2006 Uterine natural killer cells: a specialized differentiation regulated by ovarian hormones. Immunological Reviews 214, 161-185.
69. Cunningham BA, Hemperly JJ, Murray BA et al. 1987 Neural cell adhesion molecule: structure, imumunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science 236, 799-806.
70. Cuturi MC, Anegon I, Sherman F et al. 1989 Production of hematopoietic colony stimulating factors by human natural killer cells. Journal of Experimental Medicine 169, 569-583.
71. D'Andrea A, Chang C, Franz-Bacon K et al. 1995 Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. Journal of Immunology 155, 2306-2310.
72. Dam J, Guan R, Natarajan K et al. 2003 Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b). Nature Immunology 4, 1213-1222.
73. Daniels BF, Karlhofer FM, Seaman WE et al. 1994 A natural killer cell receptor specific for a major histocompatibility complex class I molecule. Journal of Experimental Medicine 180, 687-692.
74. Daniels KA, Devora G, Lai WC et al. 2001 Murine cytomegalovirus is regulated by a discrete subset of natural killer cells reactive with monoclonal antibody to Ly49h. Journal of Experimental Medicine 194, 29-44.
75. Degliantoni G, Murphy M, Kobayashi M et al. 1985 Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferon. Journal of Experimental Medicine 162, 1512-1530.
76. Depatie C, Muise E, Lepage P et al. 1997 High-resolution linkage map in the proximity of the host resistance locus CMV1. Genomics 39, 154-163.
77. Diefenbach A, Raulet DH 2001 Strategies for target cell recognition by natural killer cells. Immunological Reviews 181, 170-184.
78. Diefenbach A, Tomasello E, Lucas M et al. 2002 Selective associations with signaling molecules determine stimulatory versus costimulatory activity of NKG2D. Nature Immunology 3, 1142-1149.
79. Diefenbach A, Jensen ER, Jamieson AM et al. 2001 Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity. Nature 413, 165-171.
80. Diefenbach A, Jamieson AM, Liu SD et al. 2000 Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nature Immunology 1, 119-126.
81. DiSanto JP, Muller W, Guy-Grand D et al. 1995 Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain. Proceedings of the National Academy of Sciences of the USA 92, 377-381.
82. Dohring C, Colonna M 1996 Human natural killer cell inhibitory receptors bind to HLA class I molecules. European Journal of Immunology 26, 365-369.
83. Dorfman JR, Raulet DH 1998 Acquisition of Ly49 receptor expression by developing natural killer cells. Journal of Experimental Medicine 187, 609-618.
84. Dorner BG, Scheffold A, Rolph MS et al. 2002 MIP-1alpha, MIP-1beta, RANTES, and ATAC/lymphotactin function together with IFN-gamma as type 1 cytokines. Proceedings of the National Academy of Sciences of the USA 99, 6181-6186.
85. Doucey MA, Scarpellino L, Zimmer J et al. 2004 Cis association of Ly49A with MHC class I restricts natural killer cell inhibition. Nature Immunology 5, 328-336.
86. Dubois S, Mariner J, Waldmann TA et al. 2002 IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells. Immunity 17, 537-547.
87. Dunn C, Chalupny NJ, Sutherland CL et al. 2003 Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity. Journal of Experimental Medicine 197, 1427-1439.
88. Edelson BT, Li Z, Pappan LK et al. 2004 Mast cell-mediated inflammatory responses require the alpha2 beta1 integrin. Blood 103, 2214-2220.
89. Ellis SA, Palmer MS, McMichael AJ 1990 Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA class I molecule. Journal of Immunology 144, 731-735.
90. Engel P, Eck MJ, Terhorst C 2003 The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease. Nature Reviews Immunology 3, 813-821.
91. Falco M, Biassoni R, Bottino C et al. 1999 Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells. Journal of Experimental Medicine 190, 793-802.
92. Fan QR, Long EO, Wiley DC 2001 Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex. Nature Immunology 2, 452-460.
93. Fan QR, Garboczi DN, Winter CC et al. 1996 Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex molecule. Proceedings of the National Academy of Sciences of the USA 93, 7178-7183.
94. Faulk WP, Temple A 1976 Distribution of beta2 microglobulin and HLA in chorionic villi of human placentae. Nature 262, 799-802.
95. Ferris PJ, Armbrust EV, Goodenough UW 2002 Genetic structure of the mating-type locus of Chlamydomonas reinhardtii. Genetics 160, 181-200.
96. Forbes CA, Brown MG, Cho R et al. 1997 The Cmv1 host resistance locus is closely linked to the Ly49 multigene family within the natural killer cell gene complex on mouse chromosome 6. Genomics 41, 406-413.
97. Franksson L, Sundback J, Achour A et al. 1999 Peptide dependency and selectivity of the NK cell inhibitory receptor Ly-49C. European Journal of Immunology 29, 2748-2758.
98. Fuchs A, Cella M, Giurisato E et al. 2004 Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). Journal of Immunology 172, 3994-3998.
99. Furukawa H, Iizuka K, Poursine-Laurent J et al. 2002 A ligand for the murine NK activation receptor Ly-49D: activation of tolerized NK cells from beta(2)-microglobulin-deficient mice. Journal of Immunology 169, 126-136.
100. Garni-Wagner BA, Purohit A, Mathew PA et al. 1993 A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells. Journal of Immunology 151, 60-70.
101. Gasser S, Orsulic S, Brown EJ et al. 2005 The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 436, 1186-1190.
102. Gazit R, Gruda R, Elboim M et al. 2006 Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nature Immunology 7, 517-523.
103. Gilfillan S, Ho EL, Cella M et al. 2002 NKG2D recruits two distinct adapters to trigger natural killer cell activation and costimulation. Nature Immunology 3, 1150-1155.
104. Giorda R, Trucco M 1991 Mouse NKR-P1. A family of genes selectively coexpressed in adherent lymphokine-activated killer cells. Journal of Immunology 147, 1701-1708.
105. Girardi M, Oppenheim DE, Steele CR et al. 2001 Regulation of cutaneous malignancy by γδ T Cells. Science 294, 605-609.
106. Girl JG, Kumaki S, Ahdieh M et al. 1995 Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO Journal 14, 3654-3663.
107. Goodfellow PN, Barnstable CJ, Bodmer WF et al. 1976 Expression of HLA system antigens on placenta. Transplantation 22, 595-603.
108. Greenwood JD, Minhas K, di Santo JP et al. 2000 Ultrastructural studies of implantation sites from mice deficient in uterine natural killer cells. Placenta 21, 693-702.
109. Groh V, Bruhl A, El-Gabalawy H et al. 2003 Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the USA 100, 9452-9457.
110. Groh V, Wu J, Yee C et al. 2002 Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 419, 734-738.
111. Groh V. Rhinehart R, Randolph-Habecker J et al. 2001 Costimulation of CD8αβ T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nature Immunology 2, 255-260.
112. Groh V, Bahram S, Bauer S et al. 1996 Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium. Proceedings of the National Academy of Sciences of the USA 93, 12445-12450.
113. Grundemann C, Bauer M, Schweier O et al. 2006 Cutting edge: Identification of E-cadherin as a ligand for the murine killer cell lectin-like receptor G1. Journal of Immunology 176, 1311-1315.
114. Guimond MJ, Wang B, Croy BA 1998 Engraftment of bone marrow from severe combined immunodeficient (SCID) mice reverses the reproductive deficits in natural killer cell-deficient tg epsilon 26 mice. Journal of Experimental Medicine 187, 217-223.
115. Guimond MJ, Luross JA, Wang BP et al. 1997 Absence of natural killer cells during murine pregnancy is associated with reproductive compromise in TGE26 mice. Biology of Reproduction 56, 169-179.
116. Gumperz JE, Litwin V, Phillips JH et al. 1995 The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. Journal of Experimental Medicine 181, 1133-1144.
117. Guthmann MD, Tal M, Pecht I 1995 A secretion inhibitory signal transduction molecule on mast cells is another C-type lectin. Proceedings of the National Academy of Sciences of the USA 92, 9397-9401.
118. Hackett J, Jr., Bosma GC, Bosma MJ et al. 1986 Transplantable progenitors of natural killer cells are distinct from those of T and B lymphocytes. Proceedings of the National Academy of Sciences of the USA 83, 3427-3431.
119. Hamann J, Montgomery KT, Lau S et al. 1997 AICL: a new activation-induced antigen encoded by the human NK gene complex. Immunogenetics 45, 295-300.
120. Hamerman JA, Ogasawara K, Lanier LL 2004 Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor. Journal of Immunology 172, 2001-2005.
121. Hanke T, Takizawa H, McMahon CW et al. 1999 Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 11, 67-77.
122. Hanna J, Goldman-Wohl D, Hamani Y et al. 2006 Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nature Medicine 12, 1065-1074.
123. Hasan M, Krmpotic A, Ruzsics Z et al. 2005 Selective down-regulation of the NKG2D ligand H60 by mouse cytomegalovirus m155 glycoprotein. Journal of Virology 79, 2920-2930.
124. Hazenbos WLW, Gessner JE, Hofhuis FMA et al. 1996 Impaired IgG-dependent anaphylaxis and arthus reaction in Fc-gamma-RIII (CD16) deficient mice. Immunity 5, 181-188.
125. Held W, Cado D, Raulet DH 1996a Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. Journal of Experimental Medicine 184, 2037-2041.
126. Held W, Dorfman JR, Wu MF et al. 1996b Major histocompatibility complex class I dependent skewing of the natural killer cell LY49 receptor repertoire. European Journal of Immunology 26, 2286-2292.
127. Henkart PA 1994 Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules. Immunity 1, 343-346.
128. Herberman RB, Nunn ME, Lavrin DH 1975 Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity. International Journal of Cancer 16, 216-229.
129. Hercend T, Griffin JD, Bensussan A et al. 1985 Generation of monoclonal antibodies to a human natural killer clone: Characterization of two natural killer associated antigens, NKH1A and NKH2, expressed on subsets of large granular lymphocytes. Journal of Clinical Investigation 75, 932-943.
130. Hiby SE, Walker JJ, O'Shaughnessy K M et al. 2004 Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. Journal of Experimental Medicine 200, 957-965.
131. Hiby SE, King A, Sharkey AM et al. 1997 Human uterine NK cells have a similar repertoire of killer inhibitory and activatory receptors to those found in blood, as demonstrated by RT-PCR and sequencing. Molecular Immunology 34, 419-430.
132. Ho EL, Heusel JW, Brown MG et al. 1998 Murine Nkg2d and Cd94 are clustered within the natural killer complex and are expressed independently in natural killer cells. Proceedings of the National Academy of Sciences of the USA 95, 6320-6325.
133. Hoelsbrekken SE, Nylenna O, Saether PC et al. 2003 Cutting edge: molecular cloning of a killer cell Ig-like receptor in the mouse and rat. Journal of Immunology 170, 2259-2263.
134. Hoglund P, Ohlen C, Carbone E et al. 1991 Recognition of β2-microglobulin-negative β2m - T-cell blasts by natural killer cells from normal but not from β2m-mice: nonresponsiveness controlled by βm - bone marrow in chimeric mice. Proceedings of the National Academy of Sciences of the USA 88, 10332-10336.
135. Hollyoake M, Campbell RD, Aguado B 2005 NKp30 (NCR3) is a pseudogene in 12 inbred and wild mouse strains, but an expressed gene in Mus caroli. Molecular Biology and Evolution 22, 1661-1672.
136. Houchins JP, Lanier LL, Niemi EC et al. 1997 Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C. Journal of Immunology 158, 3603-3609.
137. Houchins JP, Yabe T, McSherry C et al. 1991 DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. Journal of Experimental Medicine 173, 1017-1020.
138. Hue S, Mention JJ, Monteiro RC et al. 2004 A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity 21, 367-377.
139. Idris AH, Smith HRC, Mason LH et al. 1999 The natural killer cell complex genetic locus, Chok, encodes Ly49D, a target recognition receptor that activates natural killing. Proceedings of the National Academy of Sciences of the USA 96, 6330-6335.
140. Iizuka K, Naidenko OV, Plougastel BF et al. 2003 Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors. Nature Immunology 4, 801-807.
141. Iizuka K, Chaplin DD, Wang Y et al. 1999 Requirement for membrane lymphotoxin in natural killer cell development. Proceedings of the National Academy of Sciences of the USA 96, 6336-6340.
142. Ito M, Maruyama T, Saito N et al. 2006 Killer cell lectin-like receptor G1 binds three members of the classical cadherin family to inhibit NK cell cytotoxicity. Journal of Experimental Medicine 203, 289-295.
143. Kagi D, Ledermann B, Burki K et al. 1994 Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369, 31-37.
144. Kane KP 1994 Ly-49 mediates EL4 lymphoma adhesion to isolated class I major histocompatibility complex molecules. Journal of Experimental Medicine 179, 1011-1015.
145. Karlhofer FM, Hunziker R, Reichlin A et al. 1994 Host MHC class I molecules modulate in vivo expression of a NK cell receptor. Journal of Immunology 153, 2407-2416.
146. Karlhofer FM, Ribaudo RK, Yokoyama WM 1992a MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells. Nature 358, 66-70.
147. Karlhofer FM, Ribaudo RK, Yokoyama WM 1992b The interaction of Ly-49 with H-2Dd globally inactivates natural killer cell cytolytic activity. Transactions of the Association of American Physicians 105, 72-85.
148. Karlhofer FM, Yokoyama WM 1991 Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways. Journal of Immunology 146, 3662-3673.
149. Kärre K 1985 Role of target histocompatibility antigens in regulation of natural killer activity: A reevaluation and a hypothesis. In: Herberman RB, Callewaert DM (eds) Mechanisms of Cytotoxicity by NK Cells, Academic Press, Orlando, pp. 81-103.
150. Kärre K, Ljunggren H-G, Piontek G et al. 1986 Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319, 675-678.
151. Kasai M, Iwamori M, Nagai Y et al. 1980 A glycolipid on the surface of mouse natural killer cells. European Journal of Immunology 10, 175-180.
152. Katz G, Markel G, Mizrahi S et al. 2001 Recognition of HLA-Cw4 but not HLA-Cw6 by the NK cell receptor killer cell Ig-like receptor two-domain short tail number 4. Journal of Immunology 166, 7260-7267.
153. Kelley J, Walter L, Trowsdale J 2005 Comparative genomics of natural killer cell receptor gene clusters. PLoS Genetics 1, 129-139.
154. Kennedy MK, Glaccum M, Brown SN et al. 2000 Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. Journal of Experimental Medicine 191, 771-780.
155. Kiessling R, Klein E, Wigzell H 1975 Natural killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells: specificity and distribution according to genotype. European Journal of Immunology 5, 112-117.
156. Kim S, Poursine-Laurent J, Truscott SM et al. 2005 Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436, 709-713.
157. King A, Allan DS, Bowen M et al. 2000a HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. European Journal of Immunology 30, 1623-1631.
158. King A, Burrows TD, Hiby SE et al. 2000b Surface expression of HLA-C antigen by human extravillous trophoblast. Placenta 21, 376-387.
159. King A, Boocock C, Sharkey AM et al. 1996 Evidence for the expression of HLA-C class I mRna and protein by human first trimester trophoblast. Journal of Immunology 156, 2068-2076.
160. King A, Birkby C, Loke YW 1989 Early human decidual cells exhibit NK activity against the K562 cell line but not against first trimester trophoblast. Cellular Immunology 118, 337-344.
161. Klein C, Philippe N, Le Deist F et al. 1994 Partial albinism with immunodeficiency (Griscelli syndrome). Journal of Pediatrics 125, 886-895.
162. Koller BH, Geraghty DE, Shimizu Y et al. 1988 HLA-E. A novel HLA class I gene expressed in resting T lymphocytes. Journal of Immunology 141, 897-904.
163. Koo GC, Peppard JR 1984 Establishment of monoclonal anti-NK-1.1 antibody. Hybridoma 3, 301-303.
164. Koopman LA, Kopcow HD, Rybalov B et al. 2003 Human decidual natural killer cells are a unique NK cell subset with immunomodulatory potential. Journal of Experimental Medicine 198, 1201-1212.
165. Kopcow HD, Allan DS, Chen X et al. 2005 Human decidual NK cells form immature activating synapses and are not cytotoxic. Proceedings of the National Academy of Sciences of the USA 102, 15563-15568.
166. Kraft JR, Vance RE, Pohl J et al. 2000 Analysis of Qa-1(b) peptide binding specificity and the capacity of CD94/NKG2A to discriminate between Qa-1-peptide complexes. Journal of Experimental Medicine 192, 613-624.
167. Krmpotic A, Hasan M, Loewendorf A et al. 2005 NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145. Journal of Experimental Medicine 201, 211-220.
168. Krmpotic A, Busch DH, Bubic I et al. 2002 MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo. Nature Immunology 3, 529-535.
169. Kubin M, Cassiano L, Chalupny J et al. 2001 ULBP1, 2, 3: novel MHC class I-related molecules that bind to human cytomegalovirus glycoprotein UL16, activate NK cells. European Journal of Immunology 31, 1428-1437.
170. Kumar V, McNerney ME 2005 A new self: MHC-class-I-independent natural-killer-cell self-tolerance. Nature Reviews Immunology 5, 363-374.
171. Kung SK, Su RC, Shannon J et al. 1999 The NKR-P1B gene product is
172. Kupfer A, Dennert G, Singer SJ 1983 Polarization of the Golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets. Proceedings of the National Academy of Sciences of the USA 80, 7224-7228.
173. dim natural killer cells. Journal of Reproductive Immunology 70, 33-42.
174. Kveberg L, Back CJ, Dai KZ et al. 2006 The novel inhibitory NKR-P1C receptor and Ly49s3 identify two complementary, functionally distinct NK cell subsets in rats. Journal of Immunology 176, 4133-4140.
175. Lanier LL 1999 Natural killer cells fertile with receptors for HLA-G? Proceedings of the National Academy of Sciences of the USA 96, 5343-5345.
176. Lanier LL, Chang C, Phillips JH 1994 Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. Journal of Immunology 153, 2417-2428.
177. Lanier LL, Cwirla S, Yu G et al. 1989a Membrane anchoring of a human IgG Fc receptor (CD16) determined by a single amino acid. Science 246, 1611-1613.
178. Lanier LL, Testi R, Bindl J et al. 1989b Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. Journal of Experimental Medicine 169, 2233-2238.
179. Lanier LL, Ruitenberg JJ, Phillips JH 1988 Functional and biochemical analysis of CD16 antigen on natural killer cells and granulocytes. Journal of Immunology 136, 3478-3485.
180. Lanier LL, Cwirla S, Federspiel N et al. 1986a Human natural killer cells isolated from peripheral blood do not rearrange T cell receptor b chain genes. Journal of Experimental Medicine 163, 209-214.
181. Lanier LL, Le AM, Civin CI et al. 1986b The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. Journal of Immunology 136, 4480-4486.
182. Lanier LL, Phillips JH, Hackett J Jr et al. 1986c Natural killer cells: definition of a cell type rather than a function. Journal of Immunology 137, 2735-2739.
183. Lash GE, Schiessl B, Kirldey M et al. 2006 Expression of angiogenic growth factors by uterine natural killer cells during early pregnancy. Journal of Leukocyte Biology 80, 572-580.
184. Lazetic S, Chang C, Houchins JP et al. 1996 Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. Journal of Immunology 157, 4741-4745.
185. Le Bouteiller P, Rodriguez AM, Mallet V et al. 1996 Placental expression of HLA class I genes. American Journal of Reproductive Immunology 35, 216-225.
186. Lebbink RJ, de Ruiter T, Adelmeijer J et al. 2006 Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1. Journal of Experimental Medicine 203, 1419-1425.
187. Lee N, Llano M, Carretero M et al. 1998 HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Proceedings of the National Academy of Sciences of the USA 95, 5199-5204.
188. Lee RK, Spielman J, Zhao DY et al. 1996 Perform, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules used by lymphokine-activated killer cells. Journal of Immunology 157, 1919-1925.
189. Lee SH, Girard S, Macma D et al. 2001 Susceptibility to mouse cytomegalovirus is associated with deletion of an activating natural killer cell receptor of the C-type lectin superfamily. Nature Genetics 28, 42-45.
190. Lenac T, Budt M, Arapovic J et al. 2006 The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60. Journal of Experimental Medicine 203, 1843-1850.
191. Leo O, Sachs DH, Samelson LE et al. 1986 Identification of monoclonal antibodies specific for the T cell receptor complex by Fc receptor-mediated CTL lysis. Journal of Immunology 137, 3874-3880.
192. Letourneur O, Kennedy IC, Brini AT et al. 1991 Characterization of the family of dimers associated with Fc receptors (Fc epsilon RI and Fc gamma RIII). Journal of Immunology 147, 2652-2656.
193. Li P, McDermott G, Strong RK 2002 Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D. Immunity 16, 77-86.
194. Li P, Morris DL, Willcox BE et al. 2001 Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA. Nature Immunology 2, 443-451.
195. Li P, Willie ST, Bauer S et al. 1999 Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand. Immunity 10, 577-584.
196. Li XF, Charnock-Jones DS, Zhang E et al. 2001 Angiogenic growth factor messenger ribonucleic acids in uterine natural killer cells. Journal of Clinical Endocrinology and Metabolism 86, 1823-1834.
197. Liao NS, Bix M, Zijlstra M et al. 1991 MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253, 199-202.
198. Lieberman J 2003 The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal. Nature Reviews Immunology 3, 361-370.
199. Litwin V, Gumperz J, Parham P et al. 1994 NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. Journal of Experimental Medicine 180, 537-543.
200. Liu CP, Ueda R, She J et al. 1993 Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine. EMBO Journal 12, 4863-4875.
201. Llano M, Lee N, Navarro F et al. 1998 HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer. European Journal of Immunology 28, 2854-2863.
202. Lodoen MB, Abenes G, Umamoto S et al. 2004 The cytomegalovirus m155 gene product subverts natural killer cell antiviral protection by disruption of H60-NKG2D interactions. Journal of Experimental Medicine 200, 1075-1081.
203. Lodoen M, Ogasawara K, Hamerman JA et al. 2003 NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules. Journal of Experimental Medicine 197, 1245-1253.
204. Lodolce JP, Boone DL, Chai S et al. 1998 IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9, 669-676.
205. Long EO 1999 Regulation of immune responses through inhibitory receptors. Annual Review of Immunology 17, 875-904.
206. Long EO, Burshtyn DN, Clark WP et al. 1997 Killer cell inhibitory receptors-diversity, specificity, and function. Immunological Reviews 155, 135-144.
207. Long EO, Colonna M, Lanier LL 1996 Inhibitory MHC class I receptors on NK and T cells: a standard nomenclature. Immunology Today 17, 100.
208. Lucas M, Schachterle W, Oberle K et al. 2007 Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity 26, 503-517.
209. Luque I, Solana R, Galiani MD et al. 1996 Threonine 80 on HLA-B27 confers protection against lysis by a group of natural killer clones. European Journal of Immunology 26, 1974-1977.
210. Maenaka K, Juji T, Nakayama T et al. 1999 Killer cell immunoglobulin receptors and T cell receptors bind peptide-major histocompatibility complex class I with distinct thermodynamic and kinetic properties. Journal of Biological Chemistry 274, 28329-28334.
211. Makrigiannis AP, Patel D, Goulet ML et al. 2005 Direct sequence comparison of two divergent class I MHC natural killer cell receptor haplotypes. Genes and Immunity 6, 71-83.
212. Makrigiannis AP, Pau AT, Saleh A et al. 2001 Class I MHC-binding characteristics of the 129/J Ly49 repertoire. Journal of Immunology 166, 5034-5043.
213. Manaster I, Mandelboim O 2007 The unique properties of human NK cells in the uterine mucosa. Placenta. doi:10.1016/j.placenta.2007.10.006.
214. Mandelboim O, Lieberman N, Lev M et al. 2001 Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature 409, 1055-1060.
215. Mandelboim O, Reyburn HT, Sheu EG et al. 1997 The binding site of NK receptors on HLA-C molecules. Immunity 6, 341-350.
216. Mandelboim O, Reyburn HT, Valesgomez M et al. 1996 Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules. Journal of Experimental Medicine 184, 913-922.
217. Markel G, Mussaffi H, Ling KL et al. 2004 The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients. Blood 103, 1770-1778.
218. Markel G, Wolf D, Hanna J et al. 2002 Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions. Journal of Clinical Investigation 110, 943-953.
219. Mason LH, Anderson SK, Yokoyama WM et al. 1996 The Ly-49D receptor activates murine natural killer cells. Journal of Experimental Medicine 184, 2119-2128.
220. Mason LH, Ortaldo JR, Young HA et al. 1995 Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2). Journal of Experimental Medicine 182 293-303
221. Matsumoto N, Mitsuki M, Tajima K et al. 2001a The functional binding site for the C-type lectin-like natural killer cell receptor Ly49A spans three domains of its major histocompatibility complex class I ligand. Journal of Experimental Medicine 193, 147-158.
222. d inside and outside of the peptide binding groove. Journal of Immunology 166, 4422-4428.
223. Matsumoto N, Ribaudo RK, Abastado J-P et al. 1998 The lectin-like NK cell receptor Ly-49A recognizes a carbohydrate-independent epitope on its MHC class I ligand. Immunity 8, 245-254.
224. McFarland BJ, Kortemme T, Yu SF et al. 2003 Symmetry recognizing asymmetry: analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and MHC class I-like ligands. Structure (Cambridge) 11, 411-422.
225. Mehta IK, Smith HRC, Wang J et al. 2001a A 'chimeric' C57L-derived Ly49 inhibitory receptor resembling the Ly49D activation receptor. Cellular Immunology 209, 29-41.
226. Mehta IK, Wang J, Roland J et al. 2001b Ly49A allelic variation and MHC class I specificity. Immunogenetics 53, 572-583.
227. Meresse B, Chen Z, Ciszewski C et al. 2004 Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity 21, 357-366.
228. Meyaard L, van der Vuurst de Vries AR, de Ruiter T et al. 2003 Retraction. Journal of Experimental Medicine 198, 1129.
229. Meyaard L, van der Vuurst de Vries AR, de Ruiter T et al. 2001 The epithelial cellular adhesion molecule (Ep-CAM) is a ligand for the leukocyte-associated immunoglobulin-like receptor (LAIR). Journal of Experimental Medicine 194, 107-112.
230. Michaelsson J, Achour A, Rolle A et al. 2001 MHC Class I Recognition by NK receptors in the Ly49 family is strongly influenced by the beta(2)-microglobulin subunit. Journal of Immunology 166, 7327-7334.
231. Mitsuki M, Matsumoto N, Yamamoto K 2004 A species-specific determinant on beta2-microglobulin required for Ly49A recognition of its MHC class I ligand. International Immunology 16, 197-204.
232. Moffett A, Loke C 2006 Immunology of placentation in eutherian mammals. Nature Reviews Immunology 6, 584-594.
233. Moffett-King A 2002 Natural killer cells and pregnancy. Nature Reviews Immunology 2, 656-663.
234. Mombaerts P, Iacomini J, Johnson RS et al. 1992 RAG-1-deficient mice have no mature B and T lymphocytes. Cell 68, 869-877.
235. Montel AH, Bochan MR, Hobbs JA et al. 1995 Fas involvement in cytotoxicity mediated by human NK cells. Cellular Immunology 166, 236-246.
236. Moretta A, Biassoni R, Bottino C et al. 1997 Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes. Immunological Reviews 155, 105-117.
237. Moretta A, Sivori S, Vitale M et al. 1995 Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. Journal of Experimental Medicine 182, 875-884.
238. + natural killer cells. Role in cell activation and regulation of cytolytic function. Journal of Experimental Medicine 171, 695-714.
239. Moretta L, Bottino C, Pende D et al. 2006 Surface NK receptors and their ligands on tumor cells. Seminars in Immunology 18, 151-158.
240. Nakamura MC, Linnemeyer PA, Niemi EC et al. 1999a Mouse Ly-49D recognizes H-2Dd and activates natural killer cell cytotoxicity. Journal of Experimental Medicine 189, 493-500.
241. Nakamura MC, Naper C, Niemi EC et al. 1999b Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor. Journal of Immunology 163, 4694-4700.
242. Nakamura MC, Niemi EC, Fisher MJ et al. 1997 Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the Shp-1 tyrosine phosphatase. Journal of Experimental Medicine 185, 673-684.
243. Nasrallah JB 2002 Recognition and rejection of self in plant reproduction. Science 296, 305-308.
244. Natarajan K, Dimasi N, Wang J et al. 2002 Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination. Annual Review of Immunology 20, 853-885.
245. Navarro F, Llano M, Bellon T et al. 1999 The ILT2(LIR1) and CD94/ NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells. European Journal of Immunology 29, 277-283.
246. Neville MJ, Campbell RD 1999 A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC. Journal of Immunology 162, 4745-4754.
247. Nicoll G, Avril T, Lock K et al. 2003 Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms. European Journal of Immunology 33, 1642-1648.
248. Nishikawa K, Saito S, Morii T et al. 1991 Accumulation of CD16-CD56+ natural killer cells with high affinity interleukin 2 receptors in human early pregnancy decidua. International Immunology 3, 743-750.
249. O'Callaghan CA, Cerwenka A, Willcox BE et al. 2001 Molecular competition for NKG2D: H60 and RAE1 compete unequally for NKG2D with dominance of H60. Immunity 15, 201-211.
250. Ogasawara K, Hamerman JA, Ehrlich LR et al. 2004 NKG2D blockade prevents autoimmune diabetes in NOD mice. Immunity 20, 757-767.
251. Olsson MY, Karre K, Sentman CL 1995 Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proceedings of the National Academy of Sciences of the USA 92, 1649-1653.
252. Olsson-Alheim MY, Sundback J, Karre K et al. 1999 The MHC class I molecule H-2Dp inhibits murine NK cells via the inhibitory receptor Ly49A. Journal of Immunology 162, 7010-7014.
253. Orihuela M, Margulies DH, Yokoyama WM 1996 The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand. Proceedings of the National Academy of Sciences of the USA 93, 11792-11797.
254. Oshimi Y, Oda S, Honda Y et al. 1996 Involvement of Fas ligand and Fas-mediated pathway in the cytotoxicity of human natural killer cells. Journal of Immunology 157, 2909-2915.
255. Pende D, Cantoni C, Rivera P et al. 2001 Role of NKG2D in tumor cell lysis mediated by human NK cells: co-operation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin. European Journal of Immunology 31, 1076-1086.
256. Pende D, Parolini S, Pessino A et al. 1999 Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells. Journal of Experimental Medicine 190, 1505-1516.
257. Pende D, Biassoni R, Cantoni C et al. 1996 The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer. Journal of Experimental Medicine 184, 505-518.
258. Perou CM, Moore KJ, Nagle DL et al. 1996 Identification of the murine beige gene by YAC complementation and positional cloning. Nature Genetics 13, 303-308.
259. Perussia B, Tutt MM, Qiu WQ et al. 1989 Murine natural killer cells express functional Fc gamma receptor II encoded by the Fc gamma R alpha gene. Journal of Experimental Medicine 170, 73-86.
260. Pessino A, Sivori S, Bottino C et al. 1998 Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. Journal of Experimental Medicine 188, 953-960.
261. Pham CT, Ley TJ 1999 Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo. Proceedings of the National Academy of Sciences of the USA 96, 8627-8632.
262. Phillips JH, Chang CW, Mattson J et al. 1996 CD94 and a novel associated protein (94ap) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes. Immunity 5, 163-172.
263. Phillips JH, Hori T, Nagler A et al. 1992 Ontogeny of human natural killer (NK) cells: fetal NK cells mediate cytolytic function and express cytoplasmic CD3 epsilon,delta proteins. Journal of Experimental Medicine 175, 1055-1066.
264. Plougastel B, Trowsdale J 1997 Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes. European Journal of Immunology 27, 2835-2839.
265. Plougastel BF, Yokoyama WM 2006 Extending missing-self? Functional interactions between lectin-like NKrp1 receptors on NK cells with lectin-like ligands. Current Topics in Microbiology and Immunology 298, 77-89.
266. Plougastel B, Dubbelde C, Yokoyama WM 2001a Cloning of Clr, a new family of lectin-like genes localized between mouse Nkrp1a and CD69 genes. Immunogenetics 53, 209-214.
267. Plougastel B, Matsumoto K, Dubbelde C et al. 2001b Analysis of a 1-Mb BAC contig overlapping the mouse Nkrp1 cluster of genes: cloning of three new Nkrp1 members, Nkrp1d, Nkrp1e, and Nkrp1f. Immunogenetics 53, 592-598.
268. Ponte M, Cantoni C, Biassoni R et al. 1999 Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor. Proceedings of the National Academy of Sciences of the USA 96, 5674-5679.
269. Proteau MF, Rousselle E, Makrigiannis AP 2004 Mapping of the BALB/c Ly49 cluster defines a minimal natural killer cell receptor gene repertoire. Genomics 84, 669-677.
270. Quillet A, Presse F, Marchiol-Foumigault C et al. 1988 Increased resistance to non-MHC-restricted cytotoxicity related to HLA A,B expression. Direct demonstration using beta 2-microglobulin-transfected Daudi cells. Journal of Immunology 141, 17-20.
271. Rabinovich B, Li J, Wolfson M et al. 2006 NKG2D splice variants: a reexamination of adaptor molecule associations, Immunogenetics 58, 81-88.
272. Radaev S, Rostro B, Brooks AG et al. 2001 Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3. Immunity 15, 1039-1049.
273. Radosavljevic M, Cuillerier B, Wilson MJ et al. 2002 A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3. Genomics 79, 114-123.
274. Rajagopalan S, Long EO 1999 A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells. Journal of Experimental Medicine 189, 1093-1100.
275. Rajagopalan S, Long EO 1998 Zinc bound to the killer cell-inhibitory receptor modulates the negative signal in human NK cells. Journal of Immunology 161, 1299-1305.
276. Rajagopalan S, Long EO 1997 The direct binding of a p58 killer cell inhibitory receptor to human histocompatibility leukocyte antigen (HLA)-Cw4 exhibits peptide selectivity. Journal of Experimental Medicine 185, 1523-1528.
277. Raulet DH, Held W, Correa I et al. 1997 Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors. Immunological Reviews 155, 41-52.
278. Ravetch JV, Kinet JP 1991 Fc receptors. Annual Review of Immunology 9, 457-491.
279. Regunathan J, Chen Y, Wang D, et al. 2005 NKG2D receptor-mediated NK cell function is regulated by inhibitory Ly49 receptors. Blood 105, 233-240.
280. Revell PA, Grossman WJ, Thomas DA et al. 2005 Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions. Journal of Immunology 174, 2124-2131.
281. Ritz J, Campen TJ, Schmidt RE et al. 1985 Analysis of T-cell receptor gene rearrangement and expression in human natural killer clones. Science 228, 1540-1543.
282. Roberts AI, Lee L, Schwarz E et al. 2001 Cutting edge: NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment. Journal of Immunology 167, 5527-5530.
283. Rolink A, ten Boekel E, Melchers F et al. 1996 A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors. Journal of Experimental Medicine 183, 187-194.
284. Rosen DB, Bettadapura J, Alsharifi M et al. 2005 Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. Journal of Immunology 175, 7796-7799.
285. Rosen DB, Araki M, Hamerman JA et al. 2004 A Structural basis for the association of DAP12 with mouse, but not human, NKG2D. Journal of Immunology 173, 2470-2478.
286. Rutishauser U, Acheson A, Hall AK et al. 1988 The neural cell adhesion molecule (NCAM) as a regulator of cell-cell interactions. Science 240, 53-57.
287. Ryan EJ, Marshall AJ, Magaletti D et al. 2002 Dendritic cell-associated lectin-1: a novel dendritic cell-associated, C-type lectin-like molecule enhances T cell secretion of IL-4. Journal of Immunology 169, 5638-5648.
288. Ryan JC, Turck J, Niemi EC et al. 1992 Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules. Journal of Immunology 149, 1631-1635.
289. Saito S, Nishikawa K, Morii T et al. 1993 Cytokine production by CD16-CD56bright natural killer cells in the human early pregnancy decidua. International Immunology 5, 559-563.
290. Salcedo M, Bousso P, Ljunggren HG et al. 1998 The Qa-1b molecule binds to a large subpopulation of murine NK cells. European Journal of Immunology 28, 4356-4361.
291. Saleh A, Davies GE, Pascal V et al. 2004 Identification of probabilistic transcriptional switches in the Ly49 gene cluster: a eukaryotic mechanism for selective gene activation. Immunity 21, 55-66.
292. Scalzo AA, Lyons PA, Fitzgerald NA, et al. 1995 The BALB.B6-Cmv1r mouse: a strain congenic for Cmv1 and the NK gene complex. Immunogenetics 41, 148-151.
293. Scalzo AA, Fitzgerald NA, Simmons A et al. 1990 Cmv-1, a genetic locus that controls murine cytomegalovirus replication in the spleen. Journal of Experimental Medicine 171, 1469-1483.
294. Screpanti V, Wallin RP, Ljunggren HG et al. 2001 A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells. Journal of Immunology 167, 2068-2073.
295. Seaman WE, Sleisenger M, Eriksson E et al. 1987 Depletion of natural killer cells in mice by monoclonal antibody to NK-1.1. Reduction in host defense against malignancy without loss of cellular or humoral immunity. Journal of Immunology 138, 4539-4544.
296. Shibuya K, Lanier LL, Phillips JH et al. 1999 Physical and functional association of LFA-1 with DNAM-1 adhesion molecule. Immunity 11, 615-623.
297. Shinkai Y, Rathbun G, Lam KP et al. 1992 RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855-867.
298. Shlapatska LM, Mikhalap SV, Berdova AG et al. 2001 CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A. Journal of Immunology 166, 5480-5487.
299. Shortman K, Wilson A, Scollay R et al. 1983 Development of large granular lymphocytes with anomalous, non-specific cytotoxicity in clones derived from Ly2+ T cells. Proceedings of the National Academy of Sciences of the USA 80, 2728-2732.
300. Sivori S, Vitale M, Morelli L et al. 1997 p46, a novel natural killer cell-specific surface molecule that mediates cell activation. Journal of Experimental Medicine 186, 1129-1136.
301. Smith HR, Heusel JW, Mehta IK et al. 2002 Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proceedings of the National Academy of Sciences of the USA 99, 8826-8831.
302. Smith HR, Chuang HH, Wang LL et al. 2000 Nonstochastic coexpression of activation receptors on murine natural killer cells. Journal of Experimental Medicine 191, 1341-1354.
303. Smith HRC, Karlhofer FM, Yokoyama WM 1994 Ly-49 multigene family expressed by IL-2-activated NK cells. Journal of Immunology 153, 1068-1079.
304. Smith KM, Wu J, Bakker AB, et al. 1998 Cutting edge: Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors. Journal of Immunology 161, 7-10.
305. Smyth MJ, Swann J, Cretney E et al. 2005 NKG2D function protects the host from tumor initiation. Journal of Experimental Medicine 202, 583-588.
306. Soderstrom K, Corliss B, Lanier LL et al. 1997 CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells. Journal of Immunology 159, 1072-1075.
307. Soloski MJ, DeCloux A, Aldrich CJ et al. 1995 Structural and functional characteristics of the class IB molecule, Qa-1. Immunological Reviews 147, 67-89.
308. Starkey PM, Sargent IL, Redman CW 1988 Cell populations in human early pregnancy decidua: characterization and isolation of large granular lymphocytes by flow cytometry. Immunology 65, 129-134.
309. Stern N, Markel G, Arnon TI et al. 2005 Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1. Journal of Immunology 174, 6692-6701.
310. Stoneman ER, Bennett M, An J et al. 1995 Cloning and characterization of 5E6(Ly-49C), a receptor molecule expressed on a subset of murine natural killer cells. Journal of Experimental Medicine 182, 305-313.
311. Suttles J, Schwarting GA, Stout RD 1986 How cytometric analysis reveals the presence of asialo GM1 on the surface membrane of alloimmune cytotoxic T lymphocytes. Journal of Immunology 136, 1586-1591.
312. Tagaya Y, Bamford RN, DeFilippis AP et al. 1996 IL-15: a pleiotropic cytokine with diverse receptor/signaling pathways whose expression is controlled at multiple levels. Immunity 4, 329-336.
313. Tahara-Hanaoka S, Shibuya K, Onoda Y et al. 2004 Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112). International Immunology 16, 533-538.
314. Takai T, Li M, Sylvestre D et al. 1994 FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 76, 519-529.
315. Takeda K, Hayakawa Y, Smyth MJ et al. 2001 Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nature Medicine 7, 94-100.
316. Tanaka T, Kitamura F, Nagasaka Y et al. 1993 Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor beta chain monoclonal antibody in mice. Journal of Experimental Medicine 178, 1103-1107.
317. Taniguchi T, Minami Y 1993 Minireview: The IL-2/IL-2 receptor system: a current overview. Cell 73, 5-8.
318. Tassi I, Colonna M 2005 The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells. Journal of Immunology 175, 7996-8002.
319. Timonen T, Ortaldo JR, Herberman RB 1981 Characteristics of human large granular lymphocytes and relationship to natural killer and K cells. Journal of Experimental Medicine 153, 569-582.
320. Tormo J, Natarajan K, Margulies DH et al. 1999 Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand. Nature 402, 623-631.
321. Tortorella D, Gewurz BE, Furman MH et al. 2000 Viral subversion of the immune system. Annual Review of Immunology 18, 861-926.
322. Tripp CS, Wolf SF, Unanue ER 1993 Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proceedings of the National Academy of Sciences of the USA 90, 3725-3729.
323. Ulbrecht M, Honka T, Person S et al. 1992 The HLA-E gene encodes two differentially regulated transcripts and a cell surface protein. Journal of Immunology 149, 2945-2953.
324. Vacca P, Pietra G, Falco M et al. 2006 Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function. Blood 108, 4078-4085.
325. Vales-Gomez M, Erskine RA, Deacon MP et al. 2001 The role of zinc in the binding of killer cell Ig-like receptors to class I MHC proteins. Proceedings of the National Academy of Sciences of the USA 98, 1734-1739.
326. Vales-Gomez M, Reyburn HT, Erskine RA et al. 1999 Kinetics and peptide dependency of the binding of the inhibitory NK receptor CD94/ NKG2-A and the activating receptor CD94/NKG2-C to HLA-E. EMBO Journal 18, 4250-4260.
327. Vales-Gomez M, Reyburn HT, Erskine RA et al. 1998a Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors. Proceedings of the National Academy of Sciences of the USA 95, 14326-14331.
328. Vales-Gomez M, Reyburn HT, Mandelboim M et al. 1998b Kinetics of interaction of HLA-C ligands with natural killer cell inhibitory receptors. Immunity 9, 337-344.
329. Vance RE, Jamieson AM, Raulet DH 1999 Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/ NKG2E on mouse natural killer cells. Journal of Experimental Medicine 190, 1801-1812.
330. Vance RE, Kraft JR, Altman JD et al. 1998 Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). Journal of Experimental Medicine 188, 1841-1848.
331. Varki A, Angata T 2006 Siglecs - the major subfamily of I-type lectins. Glycobiology 16, 1R-27R.
332. Veillette A 2006 Immune regulation by SLAM family receptors and SAP-related adaptors. Nature Reviews Immunology 6, 56-66.
333. Verma S, King A, Loke YW 1997 Expression of killer cell inhibitory receptors on human uterine natural killer cells. European Journal of Immunology 27, 979-983.
334. Vitale M, Castriconi R, Parolini S et al. 1999 The leukocyte Ig-like receptor (LIR)-1 for the cytomegalovirus UL18 protein displays a broad specificity for different HLA class I alleles: analysis of LIR-1 + NK cell clones. International Immunology 11, 29-35.
335. Vitale M, Bottino C, Sivori S et al. 1998 NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. Journal of Experimental Medicine 187, 2065-2072.
336. Wagtmann N, Biassori R, Cantoni C et al. 1995a Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 2, 439-449.
337. Wagtmann N, Rajagopalan S, Winter CC et al. 1995b Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer. Immunity 3, 801-809.
338. Wang H, Dey SK 2006 Roadmap to embryo implantation: clues from mouse models. Nature Reviews Genetics 7, 185-199.
339. Wang J, Whitman MC, Natarajan K et al. 2002 Binding of the natural killer cell inhibitory receptor Ly49A to its major histocompatibility complex class I ligand. Crucial contacts include both H-2Dd and beta 2-microglobulin. Journal of Biological Chemistry 277, 1433-1442.
340. Ware CF 2005 Network communications: lymphotoxins, LIGHT, and TNF. Annual Review of Immunology 23, 787-819.
341. Wei XH, Orr HT 1990 Differential expression of HLA-E, HLA-F, and HLA-G transcripts in human tissue. Human Immunology 29, 131-142.
342. Weis WI, Drickamer K 1996 Structural basis of lectin-carbohydrate recognition. Annual Review of Biochemistry 65, 441-473.
343. Welch AY, Kasahara M, Spain LM 2003 Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X. Immunogenetics 54, 782-790.
344. Welte SA, Sinzger C, Lutz SZ et al. 2003 Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein. European Journal of Immunology 33, 194-203.
345. Wilhelm BT, Gagnier L, Mager DL 2002 Sequence analysis of the Ly49 cluster in C57BL/6 mice: a rapidly evolving multigene family in the immune system. Genomics 80, 646-661.
346. Willcox BE, Thomas LM, Bjorkman PJ 2003 Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor. Nature Immunology 4, 913-919.
347. Wilson MJ, Torkar M, Haude A et al. 2000 Plasticity in the organization and sequences of human KIR/ILT gene families. Proceedings of the National Academy of Sciences of the USA 97, 4778-4783.
348. Wolan DW, Teyton L, Rudolph MG et al. 2001 Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A. Nature Immunology 2, 248-254.
349. Wong S, Freeman JD, Kelleher C et al. 1991 Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains. Journal of Immunology 147, 1417-1423.
350. Wu J, Chalupny NJ, Manley TJ et al. 2003 Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein. Journal of Immunology 170, 4196-4200.
351. Wu J, Cherwinski H, Spies T et al. 2000 DAP10 and DAP12 form distinct, but functionally co-operative, receptor complexes in natural killer cells. Journal of Experimental Medicine 192, 1059-1068.
352. Wu J, Song Y, Bakker AB et al. 1999 An activating immunoreceptor complex formed by NKG2D and DAP10. Science 285, 730-732.
353. Xie X, He H, Colonna M et al. 2005 Pathways participating in activation of mouse uterine natural killer cells during pregnancy. Biology of Reproduction 73, 510-518.
354. Yamada H, Shimada S, Morikawa M et al. 2005 Divergence of natural killer cell receptor and related molecule in the decidua from sporadic miscarriage with normal chromosome karyotype. Molecular Human Reproduction 11, 451-457.
355. Yokoyama WM 1997 The mother-child union: the case of missing-self and protection of the fetus. Proceedings of the National Academy of Sciences of the USA 94, 5998-6000.
356. Yokoyama WM 1995 Natural killer cells. Right-side-up and up-side-down NK-cell receptors. Current Biology 5, 982-985.
357. Yokoyama WM 1993 Recognition structures on natural killer cells. Current Opinion in Immunology 5, 67-73.
358. Yokoyama WM, Seaman WE 1993 The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annual Reviews of Immunology 11, 613-635.
359. Yokoyama WM, Kim S, French AR 2004 The dynamic life of natural killer cells. Annual Review of Immunology 22, 405-429.
360. Yokoyama WM, Ryan JC, Hunter JJ et al. 1991 cDNA cloning of mouse NKR-P1 and genetic linkage with Ly-49. Identification of a natural killer cell gene complex on mouse chromosome 6. Journal of Immunology 147, 3229-3236.
361. Yokoyama WM, Kehn PJ, Cohen DI et al. 1990 Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. Journal of Immunology 145, 2353-2358.
362. Yokoyama WM, Jacobs LB, Kanagawa O et al. 1989 A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins. Journal of Immunology 143, 1379-1386.
363. Young WW Jr, Hakomori SI, Durdik JM et al. 1980 Identification of ganglio-N-tetraosylceramide as a new cell surface marker for murine natural killer (NK) cells. Journal of Immunology 124, 199-201.
364. Yu YYL, Kumar V, Bennett M 1992 Murine natural killer cells and marrow graft rejection. Annual Review of Immunology 10, 189-213.
365. Zhang JQ, Nicoll G, Jones C et al. 2000 Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes. Journal of Biological Chemistry 275, 22121-22126.
366. Zhou H, Kartsogiannis V, Hu YS et al. 2001 A novel osteoblast-derived C-type lectin that inhibits osteoclast formation. Journal of Biological Chemistry 276, 14916-14923.