Peptide dependency and selectivity of the NK cell inhibitory receptor Ly-49C

European Journal of Immunology

Volumn 29, Issue 9, 1999, Pages 2748-2758

  Franksson, Lars ^a   Sundbäck, Jonas ^a   Achour, Adnane ^a   Bernlind, Jenny ^a   Glas, Rickard ^a   Karre, Klas ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Ly 49C; MHC; NK cell; Peptide; RMA S

Indexed keywords

IMMUNOGLOBULIN RECEPTOR; LECTIN RECEPTOR; LYMPHOCYTE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OVALBUMIN; PEPTIDE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL KILLING; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; GENETIC TRANSFECTION; MOLECULAR MODEL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 17544396947     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-4141(199909)29:09<2748::aid-immu2748>3.0.co;2-c     Document Type: Article

References (36)

1. Trinchieri, G., Biology of natural killer cells. Adv. Immunol. 1989.41:187-376.
2. NK cells, MHC class I antigens and missing self. Immunol.Rev. 1997.155-221.
3. Burshtyn, D. N., Scharenberg, A. M., Wagtmann, N., Rajagopalan, S., Berrada, K., Yj,.T., Kinet, J.-P. and Long, E., Recruitment of tyrosiné phophatase HCP by the killer cell inhibitory receptor. Immunity 1996. 4: 77-85.
4. Valiante, N. M., Phillips, J. H., Lanier, L. and Parham, P., Killer cell inhibitory receptor recognition of human leukocyte antigen (HLA) class I blocks formation of a pp36/PLC-Y signaling complex in human natural killer (NK) cells. J. Exp. Med. 1996.184: 2243-2250.
5. Nakamura, M. C., Niemi, E. C., Fisher, M. J., Schultz, L. D., Seaman, W. E. and Ryan, J. C., Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J. Exp. Med. 1997. 4: 673-684.
6. Karre, K., Ljunggren, H.-G., Piontek, G. and Kiessling, R., Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 1986. 319: 675-678.
7. Moretta, A., Biassoni, R., Bottino, C., Pende, D., Vitale, M., Poggi, M., Mingari, M. C. and Moretta, L., Major histocompatibility complex class l-specific. receptors on human natural killer and T lymphocytes. Immunol. Rev. 1997.155:105-117.
8. Smith, H. R. C., Karlhofer, F. M. and Yokoyama, W. M., Ly-49 multigene family expressed by IL-2-activated NK cells. J. Immunol. 1994.153:1068-1079.
9. Stoneman, E. R., Bennett, M., Chesnut, K. A., Wakeland, E. K., Sheerer, J. B., Siciliano, M. J., Kumar, V. and Mathew, P. A., Cloning and characterization of 5E6 (Ly-49C), a receptor molecule expressed on a subset of murine natural killer cells. J. Exp. Med. 1995. 182: 305-313.
10. Brennan, J., Lemieux, S., Freeman, J. D., Mager, D. L. and Takei, F., Heterogeneity among Ly-49C natural killer (NK) cells: characterization of highly related receptors with differing functions and expression patterns. J. Exp. Med. 1996.184: 2085-2090.
11. Sundbäck, J., Karre, K. and Sentman, C. L, Cloning of minimally divergent allelic forms of the natural killer (NK) receptor Ly-49C, differently controlled by host genes in the MHC and NK gene complexes. J. Immunol. 1996. 157: 3936-3942.
12. Franksson, L., George, E., Powis, S., Butcher, G., Howard, J, and Karre, K., Tumorigenicity conferred to lymphoma mutant by major histocompatibility complexencoded transporter gene. J. Exp. Med. 1993. 177: 201-205.
13. Salcedo, M., Momburg, F., Hämmerling, G. J. and Ljynggren, H.-G., Resistance to natural killer cell lysis conferred by TAP1/2 genes in human antigenprocessing mutant cells. J. Immunol. 1994. 152: 1702-1708.
14. Peruzzi, M., Wagtman, N. and Long, E. O., A p70 killer cell inhibitory receptor specific for several HLA-B allotypes discriminates among peptides bound to HLAB'2705. J. Exp. Med. 1996.184:1585-1590.
15. Peruzzi, M., Parker, K. C., Long, E. O. and Malnati, M. S., Peptide sequence requirements for the recognition of HLA-B*2705 by specific natural killer cells. J. Immunol. 1996. 157:3350-3356.
16. Rajagopalan, S. and Long, E. O., The direct binding of a p58 killer cell inhibitory receptor to human histocompatibility leukocyte antigen (HLA)-Cw4 exhibits peptide selectivity. J. Exp. Med. 1997.185:1523-1528.
17. Correa, I. and Raulet, D. H., Binding of diverse peptides to MHC class I molecules inhibits target cell lysis by activated natural killer cells. Immunity 1995. 2: 61-71.
18. Orihuela, M., Margulies, D. H. and Yokoyama, W. M., The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand. Proc. Natl. Acad. Sei. USA 1996. 93:11792-11797.
19. Brennan, J., Mahon, G., Mager, D. L., Jefferies, W. A. and Takei, F., Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain- interactions. J. Exp. Med. 1996. 183: 1553-1559.
20. Yu, Y. Y. L., George, T., Dorfman, J. R., Roland, J., Kumar, V. and Bennett, M., The role of Ly49A and 5E6(Ly49C) molecules in hybrid resistance mediated by murine natural killer cells against normal T cell blasts. Immunity 1996. 4: 67-76.
21. Salcedo, M., Diehl, A. D., Olsson-Alheim, M. Y., Sundbäck, J., Van Kaer, L., Karre, K. and Ljunggren, H.-G., Altered expression of Ly-49 inhibitory receptors on natural killer cells from MHC class l-deficient mice. J.lmmunol. 1997.158: 3174-3180.
22. Ljunggren, H.-G. and Karre, K., Host resistance dericted selectively against H-2-deficient lymphoma variants. J. Exp. Med. 1986.162:1745-1759.
23. Nicholls, A., Sharp, K. A. and Honig, B., Protein folding and dissociation; insights from the interfacial and thermodynaic properties of hydrocarbons. Proteins Struct. Fund. Genet. 1991.11:281-296.
24. Fremont, D. H., Stura, E. A., Matsumura, M., Peterson, P. A. and Wilson, I. A., Crystal structure of an H2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding grove. Proc. Natl. Acad. Sei. USA 1995. 92: 2479-2483.
25. Fremont, D. H., Matsumura, M., Stura, E. A., Peterson, P. A. and Wilson, I. A., Crystal structure of two viral peptides in complex with murine MHC class I H-2K. Science 1992. 257: 919-927.
26. Mandelboim, O., Reyburn, H. T., -Valés-Gômez, M., Pazmany, L., Colonna, M., Borsellino, G. and Strominger, J., Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C allels and also occurs with empty major histocompatibility complex molecules. J. Exp. Med. 1996.184: 913-922.
27. Takei, F., Brennan, J. and Mager, D. L., The Ly-49 family: genes, proteins and recognition of class I MHC. Immunol. Rev. 1997.155: 67-77.
28. George, T., Yu, Y. Y. L., Liu, J., Davenport, C., Lemieux, S., Stoneman, E., Mathew, P. A., Kumar, V. and Bennett, M., Allorecognition by murine natural killer cells: lysis of T-lymphoblasts and rejection of bonemarrow grafts. Immunol. Rev. 1997.155: 29-40.
29. Porgador, A., Yewdell, J. W., Deng, Y., Bennink, J. R. and Germain, R. N., Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 1997. 6: 715-726.
30. Mandelboim, O., Wilson, S. B., Vales-Gömez, M., Reyburn, H. T. and Strominger, J. L., Self and viral peptides can initiate lysis by autologous natural killer cells. Proc. Natl. Acad. Sei. USA 1997. 94: 4604-4609.
31. Sundbäck, J., Nakamura, M. C., Waldenström, M., Niemi, E. C., Seaman, W. E., Ryan, J. C. and Karre, K., The alpha2 domain of H-2Dd restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A. J.lmmunol. 1998.160: 5971-5978.
32. Smith, K. D. and Lutz, C. T., Alloreactive T cell recognition of MHC class I long a helices. J. Immunol. 1997. 158: 2805-2812.
33. Bjorkman, P., MHC restriction in the three dimensions: A view of T cell receptor/ligand interactions. Cell 1997. : 89: 167-170.
34. Rötzschke, O., Stevanovic, S., Jung, G., Waiden, P. and Rammensee, H. G., Exact prediction of a natural T cell epitope. Eur. J. Immunol. 1991. 21: 2891-2894.
35. Van Bleek, G. M. and Nathenson, S. G., Isolation of an enogenously processed immunodominant viral peptide from the class I H-2Kb molecule. Nature 1990. 348: 213-216.
36. Kast, W. M., Roux, L., Gurren, J., Blom, H. J. J., Voordouw, A. C., Meloen, R. H., Kolakofsky, D. and Melief, C. J. M., Protection against lethal Sendai virus infection by in vivo priming of virus specific cytotoxic T lymphocytes with a free synthetic peptide. Proc. Natl. Acad. Sei. USA 1991. 88: 2283-2287.