Pivotal role of CEACAM1 protein in the inhibition of activated decidual lymphocyte functions

Journal of Clinical Investigation

Volumn 110, Issue 7, 2002, Pages 943-953

  Markel, Gal ^a   Wolf, Dana ^b   Hanna, Jacob ^a   Gazit, Roi ^a   Goldman Wohl, Debra ^b   Lavy, Yuval ^b   Yagel, Simcha ^b   Mandelboim, Ofer ^a  

^a HEBREW UNIVERSITY   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CD16 ANTIGEN; CELL ADHESION MOLECULE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DECIDUA; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOMODULATION; LYMPHOCYTE ACTIVATION; NATURAL KILLER CELL; NIDATION; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TRANSPLANTATION TOLERANCE;

EID: 0036792506     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI0215643     Document Type: Article

References (37)

1. Bulmer, J.N., Morrison, L., Longfellow, A., Riston, A., and Pace, D. 1991. Granulated lymphocytes in human endometrium: histochemical and immunohistochemical studies. Hum. Reprod. 6:791-798.
2. Loke, Y.W., and King, A. 1995. Human implantation: cell biology and immunology. Cambridge University Press. Cambridge, United Kingdom. 1-40.
3. King, A., et al. 1991. On the nature and function of human uterine granular lymphocytes. Immunol. Today. 12:432-435.
4. King, A., et al. 2000. Recognition of trophoblast HLA class I molecules by decidual NK cell receptors: a review. Placenta. 21(Suppl.A):s81-s85.
5. King, A., et al. 2000. HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. Eur. J. Immunol. 30:1623-1631.
6. Rouas-Friess, N., Marchal-Bras Goncalie, R., Manier, C., Dausset, J., and Carosella, D.C. 1997. Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis. Proc. Natl. Acad. Sci. USA. 94:11520-11525.
7. King, A., et al. 2000. Surface expression of HLA-C antigen by human extravillous trophoblasts. Placenta. 21:376-387.
8. Cohen, G.B., et al. 1999. The selective downregulation of class I major histocompatibility complex proteins by HIV-1-infected cells from NK cells. Immunity. 10:661-671.
9. Verma, S., King, A., and Loke, Y.W. 1997. Expression of killer cell inhibitory receptors (KIR) on human uterine NK cells. Eur. J. Immunol. 27:979-983.
10. Braud, V.M., Jones, E.Y., and McMichael, A.J. 1997. The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur. J. Immunol. 27:1164-1169.
11. Biassoni, R., Bottino, C., Millo, R., Moretta, L., and Moretta, A. 1999. Natural killer cell-mediated recognition of human trophoblast. Semin. Cancer Biol. 1:13-18.
12. Ponte, M., et al. 1999. Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor. Proc. Natl. Acad. Sci. USA. 10:5674-5679.
13. Hammarstrom, S. 1999. The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. Semin. Cancer Biol. 9:67-81.
14. Watt, S.M., et al. 1994. CD66 identifies the biliary glycoprotein (BGP) adhesion molecule: cloning, expression, and adhesion functions of the BGPc splice variant. Blood. 84:200-205.
15. Markel, G., et al. 2002. CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity. J. Immunol. 168:2803-2810.
16. Wolf, D.G., Courcelle, C.T., Prichard, M.N., and Mocarski, E.S. 2001. Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsidation. Proc. Natl. Acad. Sci. USA. 98:1895-1900.
17. Morales, V.M., et al. 1999. Regulation of human intestinal intraepithelial lymphocyte cytolytic function by biliary glycoprotein (CD66a). J. Immunol. 163:1363-1370.
18. Mandelboim, O., et al. 1996. Enhancement of class II-restricted T cell responses by costimulatory NK receptors for class I MHC proteins. Science. 274:2097-2100.
19. Katz, G., Markel, G., Mizrahi, S., Arnon, T.I., and Mandelboim, O. 2001. Recognition of HLA-Cw4 but not HLA-Cw6 by the NK cell receptor killer cell Ig-like receptor two-domain short tail number 4. J. Immunol. 166:7260-7267.
20. Mandelboim, O., et al. 2001. Recognition of haemagglutinins on virusinfected cells by NKp46 activates lysis by human NK cells. Nature. 409:1055-1060.
21. Kammerer, R., Hahn, S., Singer, B.B., Luo, J.S., and Von Kleist, S. 1998. Biliary glycoprotein (CD66a), a cell adhesion molecule of the immunoglobulin superfamily, on human lymphocytes: structure, expression and involvement in T cell activation. Eur. J. Immunol. 28:3664-3674.
22. Oikawa, S., Kuroki, M., Matsuoka, Y., Kosaki, G., and Nakazato, H. 1992. Homotypic and heterotypic Ca++-independent cell adhesion activities of biliary glycoprotein, a member of carcinoembryonic antigen family, expressed on CHO cell surface. Biochem. Biophys. Res. Commun. 186:881-887.
23. Kuroki, M., et al. 2001. Identification and comparison of residues critical for cell adhesion activities of two neutrophil CD66 antigens, CEA-CAM6 and CEACAM8. J. Leukoc. Biol. 70:543-550.
24. Saito, S. 2000. Cytokine network at the feto-maternal interface. J. Reprod. Immunol. 47:87-103.
25. Demmler, G.J. 1991. Summary of a workshop on surveillance for congenital cytomegalovirus disease. Reviews of infectious diseases. 13:315-329.
26. Knipe, D.M. and Howley, P.M. 2001. Fields virology. 4th edition. Lippincott Williams & Wilkins. Philadelphia, Pennsylvania, USA. 2675-2705.
27. Barclay, A.N., et al. 1997. The leucocyte antigen factsbook. 2nd edition. Academic Press Inc. San Diego, California, USA. 1-613.
28. Parkash, V., et al. 1998. Immunohistochemical detection of Listeria antigens in the placenta in perinatal listeriosis. Int. J. Gynecol. Pathol. 17:343-350.
29. Fisher, S., Genbacev, O., Maidji, E., and Pereira, L. 2000. Human cytomegalovirus infection of placental cytotrophoblasts in vitro and in utero: implications for transmission and pathogenesis. J. Virol. 74:6808-6820.
30. Unanue, E.R. 1997. Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response. Immunol. Rev. 158:11-25.
31. Haddad, E.K., Duclos, A.J., Lapp, W.S., and Baines, M.G. 1997. Early embryo loss is associated with the prior expression of macrophage activation markers in the decidua. J. Immunol. 158:4886-4892.
32. Tortorella, D., Gewurz, B.E., Furman, M.H., Schust, D.J., and Ploegh, H.L. 2000. Viral subversion of the immune system. Annu. Rev. Immunol. 18:861-926.
33. Cosman, D., et al. 1997. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity. 7:273-282.
34. Tomasec, P., et al. 2000. Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science. 287:1031-1033.
35. Biron, C.A., Byron, K.S., and Sullivan, J.L. 1989. Severe herpesvirus infections in an adolescent without natural killer cells. N. Engl. J. Med. 320:1731-1735.
36. Groh, V., et al. 2001. Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells. Nat. Immunol. 2:255-260.
37. Cosman, D., et al. 2001. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity. 14:123-133.