Identification of probabilistic transcriptional switches in the Ly49 gene cluster: A eukaryotic mechanism for selective gene activation

Immunity

Volumn 21, Issue 1, 2004, Pages 55-66

  Saleh, Ali ^a   Davies, Gareth E ^b   Pascal, Veronique ^a   Wright, Paul W ^b   Hodge, Deborah L ^a   Cho, Edward H ^b   Lockett, Stephen J ^b   Abshari, Mehrnoosh ^b   Anderson, Stephen K ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN LY49; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBP; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; EUKARYOTE; GENE ACTIVATION; GENE CLUSTER; GENE FUNCTION; GENE SWITCHING; GENETIC CODE; GENETIC CORRELATION; GENETIC MODEL; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FAMILY; TRANSCRIPTION REGULATION;

ANIMALS; ANTIGENS, LY; CARRIER PROTEINS; GENE EXPRESSION REGULATION; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MICE; MULTIGENE FAMILY; NF-KAPPA B P50 SUBUNIT; PHOSPHORIC ACID ESTERS; PROMOTER REGIONS (GENETICS); STEROID ISOMERASES; TRANSCRIPTION FACTORS; TRANSGENES;

EID: 3142714284     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2004.06.005     Document Type: Article

References (36)

1. Anderson S.K., Ortaldo J.R., McVicar D.W. The ever-expanding Ly49 gene family. repertoire and signaling Immunol. Rev. 181:2001;79-89
2. Bix N., Locksley R.M. Independent and epigenetic regulation of the interleukin-4 alleles in CD4+ T cells. Science. 281:1998;1352-1354
3. Chen F.E., Huang D.-B., Chen Y.-Q., Ghosh G. Crystal structure of p50/p65 heterodimer of NF-κB bound to DNA. Nature. 391:1998;410-413
4. Chen D., Hinkley C.S., Henry R.W., Huang S. TBP dynamics in living human cells. constitutive association with mitotic chromosomes Mol. Biol. Cell. 13:2002;276-284
5. Christova R., Oelgeschlager T. Association of human TFIID-promoter complexes with silenced mitotic chromatin in vivo. Nat. Cell Biol. 4:2001;79-82
6. Cooper C., Henderson A., Artandi S., Avitahl N., Calame K. Ig/EBP (C/EBPγ) is a transdominant negative inhibitor of C/EBP family of transcriptional activators. Nucleic Acids Res. 23:1995;4371-4377
7. Fraser K.P., Gays F., Robinson J.H., van Beneden K., Leclercq G., Vance R.E., Raulet D.H., Brooks C.G. NK cells developing in vitro from fetal mouse progenitors express at least one member of the Ly49 family that is acquired in a time-dependent and stochastic manner independently of CD94 and NKG2. Eur. J. Immunol. 32:2002;868-878
8. Giese K., Kingsley C., Kirshner J.R., Grosschedl R. Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev. 9:1995;995-1008
9. Gosselin P., Makrigiannis A.P., Nalewaik R., Anderson S.K. Characterization of the Ly49I promoter. Immunogenetics. 51:2000;326-331
10. Held W., Kunz B. An allele-specific, stochastic gene expression process controls the expression of multiple Ly49 family genes and generates a diverse, MHC-specific NK cell receptor repertoire. Eur. J. Immunol. 28:1998;2407-2416
11. Held W., Dorfman J.R., Wu M.-F., Raulet D.H. Major histocompatibility complex class I dependent skewing of the natural killer cell Ly49 receptor repertoire. Eur. J. Immunol. 26:1996;2286-2292
12. Held W., Kunz B., Lowin-Kropf B., van de Wetering M., Clevers H. Clonal acquisition of the Ly49A NK cell receptor is dependent on the trans-acting factor TCF-1. Immunity. 11:1999;433-442
13. Holländer G.A., Zuklys S., Morel C., Mizoguchi E., Mobisson K., Simpson S., Terhorst C., Wishart W., Golan D.E., Bhan A.K., Burakoff S.J. Monoallelic expression of the interleukin-2 locus. Science. 279:1998;2118-2121
14. Hume D.A. Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression. Blood. 96:2000;2323-2328
15. Johnson A.D., Poteete A.R., Lauer G., Sauer R.T., Ackers G.K., Ptashne M. λ Repressor and cro - components of an efficient molecular switch. Nature. 294:1981;217-223
16. Kubo S., Nagasawa R., Nishimura H., Shigemoto K., Maruyama N. ATF-2-binding regulatory element is responsible for the Ly49A expression in murine T lymphoid line, EL-4. Biochim. Biophys. Acta. 1444:1999;191-200
17. Kubota A., Kubota S., Lohwasser S., Mager D.L., Takei F. Diversity of NK cell receptor repertoire in adult and neonatal mice. J. Immunol. 163:1999;212-216
18. Lanier L.L., Corliss B., Phillips J.H. Arousal and inhibition of human NK cells. Immunol. Rev. 155:1997;145-154
19. Ljunggren H.G., Karre K. In search of the "missing self" MHC molecules and NK cell recognition Immunol. Today. 11:1990;237-244
20. Makrigiannis A.P., Pau A.T., Schwartzberg P.L., McVicar D.W., Beck T.W., Anderson S.K. A BAC contig map of the Ly49 gene cluster in 129 mice reveals extensive differences in gene content relative to C57BL/6 mice. Genomics. 79:2002;437-444
21. McQueen K.L., Wilhelm B.T., Takei F., Mager D.L. Functional analysis of 5′ and 3′ regions of the closely related Ly49c and j genes. Immunogenetics. 52:2001;212-223
22. Meyers S., Downing J.R., Hiebert S.W. Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins. the runt homology domain is required for DNA binding and protein-protein interactions Mol. Cell. Biol. 13:1993;6336-6345
23. Mombaerts P. How smell develops. Nat. Neurosci. 4:2001;1192-1198
24. Montmayeur J.P., Matsunami H. Receptors for bitter and sweet taste. Curr. Opin. Neurobiol. 12:2002;366-371
25. Nerlov C., Ziff E.B. CCAAT/enhancer binding protein-α amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells. EMBO J. 14:1995;4318-4328
26. Osada S., Yamamoto H., Nishihara T., Imagawa M. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J. Biol. Chem. 271:1996;3891-3896
27. Pontiggia A., Rimini R., Harley V.R., Goodfellow P.N., Lovell-Badge R., Bianchi M.E. Sex-reversing mutations affect the architecture of SRY-DNA complexes. EMBO J. 13:1994;6115-6124
28. Ruocco R.M., Chen X., Ambrosino C., Dragonetti E., Liu W., Mallardo M., De Falco G., Palmieri C., Franzoso G., Quinto I., et al. Regulation of HIV-1 long terminal repeats by interaction of C/EBP(NF-IL6) and NF-kappaB/Rel transcription factors. J. Biol. Chem. 271:1996;22479-22486
29. Saleh A., Makrigiannis A.P., Hodge D.L., Anderson S.K. Identification of a novel Ly49 promoter that is active in bone marrow and fetal thymus. J. Immunol. 168:2002;5163-5169
30. Tanamachi D.M., Moniot D.C., Cado D., Liu S.D., Hsia J.K., Raulet D.H. Genomic Ly49A transgenes. basis of variegated Ly49A gene expression and identification of a critical regulatory element J. Immunol. 172:2004;1074-1082
31. Thanos D., Maniatis T. The high mobility group protein HMB I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene. Cell. 71:1992;777-789
32. Trinchieri G. Biology of natural killer cells. Adv. Immunol. 47:1989;187-376
33. Tsutsui H., Nakanishi K., Matsui K., Higashino K., Okamura H., Miyazawa Y., Kaneda K. IFN-gamma-inducing factor up-regulates Fas ligand-mediated cytotoxic activity of murine natural killer cell clones. J. Immunol. 157:1996;3967-3973
34. Van Beneden K.F., Stevenaert F., De Creus A., Debacker V., De Boever J., Plum J., Leclercq G. Expression of Ly49E and CD94/NKG2 on fetal and adult NK cells. J. Immunol. 166:2001;4302-4311
35. Wilhelm B.T., Gagnier L., Mager D.L. Sequence analysis of the Ly49 gene cluster in C57BL/6 mice. a rapidly evolving multigene family in the immune system Genomics. 80:2002;646-661
36. Williams N.S., Kubota A., Bennett M., Kumar V., Takei F. Clonal analysis of NK cell development from bone marrow progenitors in vitro. orderly acquisition of receptor gene expression Eur. J. Immunol. 30:2000;2074-2082