NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules

European Journal of Immunology

Volumn 30, Issue 3, 2000, Pages 920-930

  Corral, Laura ^a,b   Hanke, Thomas ^a   Vance, Russell E ^a   Cado, Dragana ^a   Raulet, David H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

KLRG1; MHC class I; NK cell ITIM

Indexed keywords

CELL ANTIGEN; DIMER; KILLER CELL LECTIN LIKE RECEPTOR G1; LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAST CELL FUNCTION ASSOCIATED ANTIGEN; MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DOWN REGULATION; IMMUNOPRECIPITATION; ISOTOPE LABELING; MOUSE; NATURAL KILLER CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; REGULATORY MECHANISM; SPLEEN CELL; T LYMPHOCYTE; TRANSGENE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, LY; CHIMERA; DOWN-REGULATION; GENE EXPRESSION; HISTOCOMPATIBILITY ANTIGENS CLASS I; KILLER CELLS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; RECEPTORS, MITOGEN; SIGNAL TRANSDUCTION;

EID: 0034001276     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200003)30:3<920::AID-IMMU920>3.0.CO;2-P     Document Type: Article

References (35)

1. Lanier, L. L., NK cell receptors. Annu. Rev. Immunol. 1998. 16: 359-393.
2. Burshtyn, D., Scharenberg, A., Wagtmann, N., Rajagopalan, S., Peruzzi, M., Kinet, J.-P. and Long, E. O., Recruitment of tyrosine phosphatase HCP by the NK cell inhibitory receptor. Immunity 1996. 4: 77-85.
3. Nakamura, M. C., Niemi, E. C., Fisher, M. J., Shultz, L. D., Seaman, W. E. and Ryan, J. C., Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity and functionally associates with the SHP-1 tyrosine phosphatase. J. Exp. Med. 1997. 185: 673-84.
4. Lanier, L. L., Corliss, B. C., Wu, J., Leong, C. and Phillips, J. H., Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 1998. 391: 703-7.
5. Olcese, L., Cambiaggi, A., Semenzato, G., Bottino, C., Moretta, A. and Vivier, E., Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells. J. Immunol. 1997. 158: 5083-5086.
6. Yokoyama, W. M. and Seaman, W. E., The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Annu. Rev. Immunol. 1993. 11: 613-635.
7. Lopez-Botet, M., Carretero, M., Bellon, T., Perez-Villar, J. J., Llano, M. and Navarro, F., The CD94/NKG2 C-type lectin receptor complex. Curr. Top. Microbiol. Immunol. 1998. 230: 41-52.
8. Wong, S., Freeman, J. D., Kelleher, C., Mager, D. and Takei, F., Ly-49 multigene family. New members of a superfamily of type II membrane proteins with lectin-like domains. J. Immunol. 1991. 147: 1417-1423.
9. b. J. Exp. Med. 1998. 188: 1841-1848.
10. Ortega Soto, E. and Pecht, I., A monoclonal antibody that inhibits secretion from rat basophilic leukemia cells and binds to a novel membrane component. J. Immunol. 1988. 141: 4324-32.
11. Butcher, S., Arney, K. L. and Cook, G. P., MAFA, an ITIM-containing receptor encoded by the human NK cell gene complex and expressed by basophils and NK cells. Eur. J. Immunol. 1998. 3755-3762.
12. Hanke, T., Corral, L., Vance, R. E. and Raulet, D. H., 2F1 antigen, the mouse homolog of the rat "mast cell function-associated antigen, is a lectin like type II transmembrane receptor expressed by natural killer cells. Eur. J. Immunol. 1999. 28: 4409-4417.
13. Guthmann, M., Tal, M. and Pecht, I., A secretion inhibitory signal transduction molecule on mast cells is another C-type lectin. Proc. Natl. Acad. Sci. USA 1995. 92: 9397-9401.
14. Raulet, D. H., Held, W., Correa, I., Dorfman, J., Wu, M.-F. and Corral, L., Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors, Immunol. Rev. 1997. 155: 41-52.
15. a encoded antigens in T cell receptor Vβ8.1 transgenic mice. EMBO J. 1989. 8: 719-727.
16. Brennan, J., Mahon, G., Mager, D. L., Jefferies, W. A. and Takei, F., Recognition of class I major histocompatibility complex molecules by Ly-49 - Specificities and domain interactions. J. Exp. Med. 1996. 183: 1553-1559.
17. Hanke, T., Takizawa, H., McMahon, C. W., Busch, D. H., Pamer, E. G., Miller, J. D., Altman, J. D., Liu, Y., Cado, D., Lemonnier, F. A., Bjorkman, P. J. and Raulet, D. H., Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 1999. 11: 67-77.
18. Held, W., Cado, D. and Raulet, D. H., Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. J. Exp. Med. 1996. 184: 2037-2041.
19. Held, W. and Raulet, D. H., Ly49A transgenic mice provide evidence for a major histocompatibility complex-dependent education process in NK cell development. J. Exp. Med. 1997. 185: 2079-2088.
20. Cyster, J. G. and Goodnow, C. C., Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. Immunity 1995. 2: 13-24.
21. Bocek, P., Jr., Guthmann, M. D. and Pecht, I., Analysis of the genes encoding the mast cell function-associated antigen and its alternatively spliced transcripts. J. Immunol. 1997. 158: 3235-3243.
22. Blaser, C., Kaufmann, M. and Pircher, H., Virus-activated CD8 T cells and lymphokine-activated NK cells express the mast cell function-associated antigen, an inhibitory C-type lectin. J. Immunol. 1998. 161: 6451-6454.
23. Karlhofer, F. M., Hunziker, R., Reichlin, A., Margulies, D. H. and Yokoyama, W. M., Host MHC class I molecules modulate in vivo expression of a NK cell receptor. J. Immunol. 1994. 153: 2407-2416.
24. Olsson, M. Y., Karre, K. and Sentman, C. L., Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proc. Natl. Acad. Sci. USA 1995. 92: 1649-1653.
25. Aldrich, C. J., DeCloux, A., Woods, A. S., Cotter, R. J., Soloski, M. J. and Forman, J., Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen. Cell 1994. 79: 649-658.
26. Long, E., Regulation of immune responses through inhibitory receptors. Annu. Rev. Immunol. 1999. 17: 875-904.
27. + cytolytic T cells. Nature 1990. 344: 742-746.
28. + T cell repertoire and anti-lymphocytic choriomeningitis virus cytolytic responses. Eur. J. Immunol. 1999. 29: 1243-1252.
29. + dendritic epidermal cells revealed by Vγ3 specific monoclonal antibody. Proc. Natl. Acad. Sci. USA 1989. 86: 4185-4189.
30. Roland, J. and Cazenave, P. A., Ly-49 antigen defines an alpha beta TCR population in i-IEL with an extrathymic maturation. Int. Immunol. 1992. 4: 699-706.
31. Mason, L., Giardina, S., Hecht, T., Ortaldo, J. and Mathieson, B., LGL-1 : A non polymorphic antigen expressed on a major population of mouse natural killer cells. J. Immunol. 1988. 140: 4403-4412.
32. Koo, G. C. and Peppard, J. R., Establishment of monoclonal anti-NK-1.1 antibody. Hybridoma 1984. 3: 301-303.
33. Gunji, Y., Vujanovic, N. L., Hiserodt, J. C., Herberman, R. B. and Gorelik, E., Generation and characterization of purified adherent lymphokine-activated killer cells in mice. J. Immunol. 1989. 142: 1748-1754.
34. Correa, I., Corral, L. and Raulet, D. H., Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells. Eur. J. Immunol. 1994. 24: 1323-1331.
35. Coles, M. C., McMahon, C. W., Takizawa, H., and Raulet, D. H., Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur. J. Immunol. 2000. 30: 236-244.