Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells

Journal of Experimental Medicine

Volumn 189, Issue 7, 1999, Pages 1149-1155

  Allan, David S J ^a   Colonna, Marco ^b   Lanier, Lewis L ^c   Churakova, Tatyana D ^c   Abrams, John S ^c   Ellis, Shirley A ^d   McMichael, Andrew J ^a   Braud, Veronique M ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^c MERCK RESEARCH LABORATORIES   (United States)

^d INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

CD94; Immunoglobulin like transcript; Killer immunoglobulin like receptor; Monocyte; Natural killer cell

Indexed keywords

HISTOCOMPATIBILITY ANTIGEN; LEUKOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN BINDING; ARTICLE; COMPLEX FORMATION; GENE CLUSTER; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KILLER CELL; LEUKEMIA CELL; MACROPHAGE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MYELOMONOCYTIC LEUKEMIA; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION REGULATION; TROPHOBLAST;

ANIMALS; ANTIGENS, CD14; BIOPOLYMERS; CELL LINE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; JURKAT CELLS; KILLER CELLS, NATURAL; MACROMOLECULAR SUBSTANCES; MEMBRANE GLYCOPROTEINS; MICE; MONOCYTES; PROTEIN BINDING; PROTEIN CONFORMATION; RATS; RECEPTORS, IGG; RECEPTORS, IMMUNOLOGIC; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 0033526054     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.7.1149     Document Type: Article

References (37)

1. Ellis, S.A., M.S. Palmer, and A.J. McMichael. 1990. Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA class I molecule. J. Immunol. 144:731-735.
2. McMaster, M.T., C.L. Librach, Y. Zhou, K.H. Lim, M.J. Janatpour, R. DeMars, S. Kovats, C. Damsky, and S.J. Fisher. 1995. Human placental HLA-G expression is restricted to differentiated cytotrophoblasts. J. Immunol. 154: 3771-3778.
3. Loke, Y.W., A. King, T. Burrows, L. Gardner, M. Bowen, S. Hiby, S. Howlett, N. Holmes, and D. Jacobs. 1997. Evaluation of trophoblast HLA-G antigen with a specific monoclonal antibody. Tissue Antigens. 50:135-146.
4. Le Bouteiller, P., A.M. Rodriguez, V. Mallet, M. Girr, T. Guillaudeux, and F. Lenfant. 1996. Placental expression of HLA class I genes. Am. J. Reprod. Immunol. 35:216-225.
5. King, A., T. Burrows, and Y.W. Loke. 1996. Human uterine natural killer cells. Nat. Immun. 15:41-52.
6. Pende, D., S. Sivori, L. Accame, L. Pareti, M. Falco, D. Geraghty, P. Le Bouteiller, L. Moretta, and A. Moretta. 1997. HLA-G recognition by human natural killer cells. Involvement of CD94 both as inhibitory and as activating receptor complex. Eur. J. Immunol. 27:1875-1880.
7. Perez-Villar, J.J., I. Melero, F. Navarro, M. Carretero, T. Bellon, M. Llano, M. Colonna, D.E. Geraghty, and M. Lopez-Botet. 1997. The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1. J. Immunol. 158:5736-5743.
8. Soderstrom, K., B. Corliss, L.L. Lanier, and J.H. Phillips. 1997. CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells. J. Immunol. 159:1072-1075.
9. Braud, V., E.Y. Jones, and A. McMichael. 1997. The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur. J. Immunol. 27:1164-1169.
10. Braud, V.M., D.S. Allan, D. Wilson, and A.J. McMichael. 1998. TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide. Curr. Biol. 8:1-10.
11. Braud, V.M., D.S. Allan, C.A. O'Callaghan, K. Soderstrom, A. D'Andrea, G.S. Ogg, S. Lazetic, N.T. Young, J.I. Bell, J.H. Phillips, et al. 1998. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature. 391:795-799.
12. Borrego, F., M. Ulbrecht, E.H. Weiss, J.E. Coligan, and A.G. Brooks. 1998. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J. Exp. Med. 187:813-818.
13. Lee, N., D.R. Goodlett, A. Ishitani, H. Marquardt, and D.E. Geraghty. 1998. HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J. Immunol. 160:4951-4960.
14. Lee, N., M. Llano, M. Carretero, A. Ishitani, F. Navarro, M. Lopez-Botet, and D.E. Geraghty. 1998. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Proc. Natl. Acad. Sci. USA. 95:5199-5204.
15. Pazmany, L., O. Mandelboim, M. Vales-Gomez, D.M. Davis, H.T. Reyburn, and J.L. Strominger. 1996. Protection from natural killer cell-mediated lysis by HLA-G expression on target cells. Science. 274:792-795.
16. Munz, C., N. Holmes, A. King, Y.W. Loke, M. Colonna, H. Schild, and H.G. Rammensee. 1997. Human histocompatibility leukocyte antigen (HLA)-G molecules inhibit NKAT3 expressing natural killer cells. J. Exp. Med. 185: 385-391.
17. Cantoni, C., S. Verdiani, M. Falco, A. Pessino, M. Cilli, R. Conte, D. Pende, M. Ponte, M.S. Mikaelsson, L. Moretta, and R. Biassoni. 1998. p49, a putative HLA class I-specific inhibitory NK receptor belonging to the immunoglobulin superfamily. Eur. J. Immunol. 28:1980-1990.
18. Samaridis, J., and M. Colonna. 1997. Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways. Eur. J. Immunol, 27: 660-665.
19. Colonna, M., F. Navarro, T. Bellon, M. Llano, P. Garcia, J. Samaridis, L. Angman, M. Cella, and M. Lopez-Botet. 1997. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186:1809-1818.
20. Colonna, M., J. Samaridis, M. Cella, L. Angman, R.L. Allen, C.A. O'Callaghan, R. Dunbar, G.S. Ogg, V. Cerundolo, and A. Rolink. 1998. Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules J. Immunol. 160:3096-3100.
21. Cella, M., C. Dohring, J. Samaridis, M. Dessing, M. Brockhaus, A. Lanzavecchia, and M. Colonna. 1997. A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J. Exp. Med. 185:1743-1751.
22. Nakajima, H., J. Samaridis, L. Angman, and M. Colonna. 1999. Human myeloid cells express an activating ILT receptor (ILTl) that associates with Fc receptor gamma-chain. J. Immunol. 162:5-8.
23. Cosman, D., N. Fanger, L. Borges, M. Kubin, W. Chin, L. Peterson, and M.L. Hsu. 1997. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity. 7:273-282.
24. Borges, L., M.L. Hsu, N. Fanger, M. Kubin, and D. Cosman. 1997. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J. Immunol. 159:5192-5196.
25. Fanger, N.A., D. Cosman, L. Peterson, S.C. Braddy, C.R. Maliszewski, and L. Borges. 1998. The MHC class 1 binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes. Eur. J. Immunol. 28:3423-3434.
26. Wagtmann, N., S. Rojo, E. Eichler, H. Mohrenweiser, and E.O. Long. 1997. A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors. Curr. Biol. 7:615-618.
27. Arm, J.P., C. Nwankwo, and K.F. Austen. 1997. Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor. J. Immunol. 159:2342-2349.
28. Ogg, G.S., and A.J. McMichael. 1998. HLA-peptide tetrameric complexes. Curr. Opin. Immunol. 10:393-396.
29. Lanier, L.L., B. Corliss, J. Wu, and J.H. Phillips. 1998. Association of DAP12 with activating CD94/NKG2C NK cell receptors. Immunity. 8:693-701.
30. Lanier, L.L., B. Corliss, and J.H. Phillips. 1997. Arousal and inhibition of human NK cells. Immunol. Rev. 155:145-154.
31. Diehl, M., C. Munz, W. Keilholz, S. Stevanovic, N. Holmes, Y.W. Loke, and H.G. Rammensee. 1996. Nonclassical HLA-G molecules are classical peptide presenters. Curr. Biol. 6:305-314.
32. Lee, N., A.R. Malacko, A. Ishitani, M.C. Chen, J. Bajorath, H. Marquardt, and D.E. Geraghty. 1995. The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association. Immunity. 3:591-600.
33. + T cells in chronic HIV infection are antigen specific. J. Exp. Med. 188:785-790.
34. + subpopulation. Immunol. Today. 17:424-428.
35. O'Doherty, U., M. Peng, S. Gezelter, W.J. Swiggard, M. Betjes, N. Bhardwaj, and R.M. Steinman. 1994. Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature. Immunology. 82: 487-493.
36. - peripheral blood cells with dendritic precursor characteristics. J. Immunol. 161:740-748.
37. Thomas, R., and P.E. Lipsky. 1994. Human peripheral blood dendritic cell subsets. Isolation and characterization of precursor and mature antigen-presenting cells. J. Immunol. 153: 4016-4028.