Engraftment of bone marrow from severe combined immunodeficient (SCID) mice reverses the reproductive deficits in natural killer cell-deficient tgε26 mice

Journal of Experimental Medicine

Volumn 187, Issue 2, 1998, Pages 217-223

  Guimond, Marie Josée ^a,c   Wang, Baoping ^b   Croy, B Anne ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; DECIDUALIZATION; FEMALE; GRAFT SURVIVAL; NATURAL KILLER CELL; NONHUMAN; PLACENTA DEVELOPMENT; PREGNANCY; PRIORITY JOURNAL; SCID MOUSE; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD3; BONE MARROW TRANSPLANTATION; DECIDUA; FEMALE; GENE EXPRESSION REGULATION; HUMANS; KILLER CELLS, NATURAL; MICE; MICE, INBRED CBA; MICE, SCID; MICE, TRANSGENIC; PLACENTA; PREGNANCY; PREGNANCY COMPLICATIONS; REPRODUCTION; TRANSGENES; TROPHOBLASTS; UTERUS;

EID: 0031985048     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.2.217     Document Type: Article

References (26)

1. Whitelaw, P.F., and B.A. Croy. 1996. Granulated lymphocytes of pregnancy. Placenta. 17:533-543.
2. Peel, S. 1989. Granulated metrial gland cells. Adv. Anat. Embryol. Cell Biol. 115:1-112.
3. King, A., and Y.W. Loke. 1991. On the nature and function of human uterine granulated lymphocytes. Immunol. Today. 12:432-435.
4. Zheng, L.M., S.V. Joag, M.B. Parr, E.L. Parr, and J.D.-E. Young. 1991. Perforin-expressing granulated metrial gland cells in murine deciduoma. J. Exp. Med. 174:1221-1226.
5. Croy, B.A., and Y. Kiso. 1993. Granulated metrial gland cells: a natural killer cell subset of the pregnant murine uterus. Microsc. Res. Tech. 25:189-200.
6. Stewart, I.J., and S. Peel. 1980. Granulated metrial gland cells in pregnant athymic mice. J. Anat. 131:217 (Abstr.).
7. Croy, B.A., C. Chapeau, N. Reed, I.J. Stewart, and S. Peel. 1991. Is there an essential requirement for bone marrow-derived cells at the fetomaternal interface during successful pregnancy? A study of pregnancies in immunodeficient mice. In Molecular and Cellular Immunobiology of the Maternal Fetal Interface. T.G. Wegmann, T.J. Gill III, and E. Nisbet-Brown, editors. Oxford University Press, New York. 168-188.
8. Guimond, M.-J., J.A. Luross, B. Wang, C. Terhorst, S. Danial, and B.A. Croy. 1997. Absence of natural killer cells during murine pregnancy is associated with reproductive compromise in Tg∈26 mice. Biol. Reprod. 56:169-179.
9. Croy, B.A., A.A. Ashkar, R.A. Foster, J.P. DiSanto, J. Magram, D. Carson, S.J. Gendler, M.J. Grusby, N. Wagner, W. Müller, and M.-J. Guimond. 1997. Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy. J. Reprod. Immunol. 35:111-133.
10. Wang, B. C. Biron, J. She, K. Higgins, M.-J. Sunshine, E. Lacy, N. Lonberg, and C. Terhorst. 1994. A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3∈ gene. Proc. Natl. Acad. Sci. USA. 91:9402-9406.
11. Wang, B., C. Levelt, M. Salio, D. Zheng, J. Sancho, C.-P. Liu, J. She, M. Huang, K. Higgins, M.-J. Sunshine, K. Eichmann, et al. 1995. Over-expression of CD3∈ transgenes blocks T lymphocyte development. Int. Immunol. 7:435-448.
12. Pijnenborg, R., W.B. Robertson, I. Brosens, and G. Dixon. 1981. Review article: trophoblast invasion and the establishment of haemochorial placentation in man and laboratory animals. Placenta. 2:71-91.
13. Wang, B., G.A. Holländer, A. Nichogiannopoulou, S.J. Simpson, J.S. Orange, J.-C. Gutierrez-Ramos, S.J. Burakoff, C.A. Biron, and C. Terhorst. 1996. Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny. Int. Immunol. 8:939-949.
14. Holländer, G.A., B. Wang, A. Nichogiannopoulou, P.P. Platenburg, W. van Ewijk, S.J. Burakoff, J.-C. Gutierrez-Ramos, and C. Terhorst. 1995. Development control point in induction of thymic cortex regulated by a subpopulation of prothymocytes. Nature. 373:350-353.
15. McLaughlin, M.K., and T.M. Keve. 1986. Pregnancy-induced changes in resistance blood vessels. Am. J. Obstet. Gynecol. 155:1296-1299.
16. Meyers, M.C., J.E. Brayden, and M.K. McLaughlin. 1993. Characteristics of vascular smooth muscle in the maternal resistance circulation during pregnancy in the rat. Am. J. Obstet. Gynecol. 169:1510-1516.
17. Cipolla, M.J., N.D. Binder, and G. Osol. 1997. Myoendometrial versus placental uterine arteries: structural, mechanical, and functional differences in late-pregnant rabbits. Am. J. Obstet. Gynecol. 177:215-221.
18. Nunokawa, Y., and S. Tanaka. 1992. Interferon-γ inhibits proliferation of rat vascular smooth muscle cells by nitric oxide generation. Biochem. Biophys. Res. Commun. 188:409-415.
19. Yallampalli, C., M. Byam-Smith, S.O. Nelson, and R.E. Garfield. 1994. Steroid hormones modulate the production of nitric oxide and cGMP in the rat uterus. Endocrinology. 134:1971-1974.
20. Norman, J.E., and I.T. Cameron. 1996. Nitric oxide in the human uterus. Reviews in Reproduction. 1:61-68.
21. Yallampalli, C., and R.E. Garfield. 1993. Inhibition of nitric oxide synthesis in rats during pregnancy produces signs similar to those of preeclampsia. Am. J. Obstet. Gynecol. 169: 1316-1320.
22. Hunt, J.S., L. Miller, D. Vassmer, and B.A. Croy. 1997. Expression of the inducible nitric oxide synthase gene in mouse uterine leukocytes and potential relationships with uterine function dunng pregnancy. Biol. Reprod. 57:827-836.
23. Parr, E.L., H.-L. Chen, M.B. Parr, and J.S. Hunt. 1995. Synthesis and granular localization of tumour necrosis factor-alpha in activated NK cells in the pregnant mouse uterus. J. Reprod. Immunol. 28:31-40.
24. Turner, C.R., K.M. Esser, E.B. Wheeldon, M. Slivjak, and E.F. Smith. 1989. Cardiovascular and pulmonary effects of human recombinant tumor necrosis factor in the conscious rat. Circ. Shock. 28:369-384.
25. Saks, S., and M. Rosenblum. 1992. Recombinant human TNF-α: preclinical studies and results from early clinical trials. Immunol. Ser. 56:567-587.
26. Moore, H.C., I. Cserhati, and K. Wilson. 1970. The duration of the fall of blood pressure following the induction of deciduomata and the administration of progesterone in steroid hypertensive rats. Acta Endocrinol. 63:242-252.