-
1
-
-
22144431929
-
Genome-wide analysis of STAT target genes
-
Alvarez JV, Frank DA. (2004). Genome-wide analysis of STAT target genes. Cancer Biol Ther 3: 1045-1050.
-
(2004)
Cancer Biol Ther
, vol.3
, pp. 1045-1050
-
-
Alvarez, J.V.1
Frank, D.A.2
-
2
-
-
0030900022
-
Roles of the N and C terminal domains of the interleukin-3 receptor alpha chain in receptor function
-
Barry SC, Korpelainen E, Sun Q, Stomski FC, Moretti PA, Wakao H et al. 1997. Roles of the N and C terminal domains of the interleukin-3 receptor alpha chain in receptor function. Blood 89: 842-852.
-
(1997)
Blood
, vol.89
, pp. 842-852
-
-
Barry, S.C.1
Korpelainen, E.2
Sun, Q.3
Stomski, F.C.4
Moretti, P.A.5
Wakao, H.6
-
3
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S et al. (2005). Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 365: 1054-1061.
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
East, C.4
Fourouclas, N.5
Swanton, S.6
-
4
-
-
0032874677
-
Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: Possible sites for intervention with anti-neoplastic drugs
-
Blalock WL, Weinstein-Oppenheimer C, Chang F, Hoyle PE, Wang XY, Algate PA et al. (1999). Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs. Leukemia 13: 1109-1166.
-
(1999)
Leukemia
, vol.13
, pp. 1109-1166
-
-
Blalock, W.L.1
Weinstein-Oppenheimer, C.2
Chang, F.3
Hoyle, P.E.4
Wang, X.Y.5
Algate, P.A.6
-
5
-
-
0029799912
-
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma
-
Bromberg JF, Horvath CM, Wen Z, Schreiber RD, Darnell JE. (1996). Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma. Proc Natl Acad Sci USA 93: 7673-7678.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7673-7678
-
-
Bromberg, J.F.1
Horvath, C.M.2
Wen, Z.3
Schreiber, R.D.4
Darnell, J.E.5
-
6
-
-
0028834634
-
Activation of the STAT3/acute phase response factor transcription factor by interleukin-5
-
Caldenhoven E, van Dijk T, Raaijmakers JA, Lammers JW, Koenderman L, De Groot RP. (1995). Activation of the STAT3/acute phase response factor transcription factor by interleukin-5. J Biol Chem 270: 25778-25784.
-
(1995)
J Biol Chem
, vol.270
, pp. 25778-25784
-
-
Caldenhoven, E.1
van Dijk, T.2
Raaijmakers, J.A.3
Lammers, J.W.4
Koenderman, L.5
De Groot, R.P.6
-
7
-
-
0029916933
-
Activation and association of Stat3 with Src in v-Src-transformed cell lines
-
Cao X, Tay A, Guy GR, Tan YH. (1996). Activation and association of Stat3 with Src in v-Src-transformed cell lines. Mol Cell Biol 16: 1595-1603.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1595-1603
-
-
Cao, X.1
Tay, A.2
Guy, G.R.3
Tan, Y.H.4
-
8
-
-
0029863169
-
Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
-
Carlesso N, Frank DA, Griffin JD. (1996). Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl. J Exp Med 183: 811-820.
-
(1996)
J Exp Med
, vol.183
, pp. 811-820
-
-
Carlesso, N.1
Frank, D.A.2
Griffin, J.D.3
-
9
-
-
0032473935
-
Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation
-
Chaturvedi P, Reddy MV, Reddy EP. (1998). Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation. Oncogene 16: 1749-1758.
-
(1998)
Oncogene
, vol.16
, pp. 1749-1758
-
-
Chaturvedi, P.1
Reddy, M.V.2
Reddy, E.P.3
-
10
-
-
0030992813
-
Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs
-
Chaturvedi P, Sharma S, Reddy EP. (1997). Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs. Mol Cell Biol 17: 3295-3304.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 3295-3304
-
-
Chaturvedi, P.1
Sharma, S.2
Reddy, E.P.3
-
11
-
-
0029923780
-
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1
-
Chin YE, Kitagawa M, Su WC, You ZH, Iwamoto Y, Fu XY. (1996). Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 272: 219-222.
-
(1996)
Science
, vol.272
, pp. 219-222
-
-
Chin, Y.E.1
Kitagawa, M.2
Su, W.C.3
You, Z.H.4
Iwamoto, Y.5
Fu, X.Y.6
-
12
-
-
0028148501
-
Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase
-
Colamonici O, Yan H, Domanski P, Handa R, Smalley D et al. (1994a). Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase. Mol Cell Biol 14: 8133-8142.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 8133-8142
-
-
Colamonici, O.1
Yan, H.2
Domanski, P.3
Handa, R.4
Smalley, D.5
-
13
-
-
0028169699
-
Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor
-
Colamonici OR, Uyttendaele H, Domanski P, Yan H, Krolewski JJ. (1994b). Ligand-independent anti-oncogenic activity of the alpha subunit of the type I interferon receptor. J Biol Chem 269: 3518-3522.
-
(1994)
J Biol Chem
, vol.269
, pp. 3518-3522
-
-
Colamonici, O.R.1
Uyttendaele, H.2
Domanski, P.3
Yan, H.4
Krolewski, J.J.5
-
14
-
-
0029157421
-
Distribution of the mammalian Stat gene family in mouse chromosomes
-
Copeland NG, Gilbert DJ, Schindler C, Zhong Z, Wen Z, Darnell Jr JE et al. (1995). Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics 29: 225-228.
-
(1995)
Genomics
, vol.29
, pp. 225-228
-
-
Copeland, N.G.1
Gilbert, D.J.2
Schindler, C.3
Zhong, Z.4
Wen, Z.5
Darnell Jr, J.E.6
-
15
-
-
0031741655
-
Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation
-
Danial NN, Losman JA, Lu T, Yip N, Krishnan K, Krolewski J et al. (1998). Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation. Mol Cell Biol 18: 6795-6804.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6795-6804
-
-
Danial, N.N.1
Losman, J.A.2
Lu, T.3
Yip, N.4
Krishnan, K.5
Krolewski, J.6
-
16
-
-
0028817880
-
Jak-STAT signaling induced by the v-abl oncogene
-
Danial NN, Pernis A, Rothman PB. (1995). Jak-STAT signaling induced by the v-abl oncogene. Science 269: 1875-1877.
-
(1995)
Science
, vol.269
, pp. 1875-1877
-
-
Danial, N.N.1
Pernis, A.2
Rothman, P.B.3
-
17
-
-
0030840464
-
STATs and gene regulation
-
Darnell Jr JE. (1997). STATs and gene regulation. Science 277: 1630-1635.
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr, J.E.1
-
18
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell Jr JE, Kerr IM, Stark GR. (1994). Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264: 1415-1421.
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell Jr, J.E.1
Kerr, I.M.2
Stark, G.R.3
-
19
-
-
0028972719
-
Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1
-
David M, Chen HE, Goelz S, Larner AC, Neel BG. (1995a). Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1. Mol Cell Biol 15: 7050-7058.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 7050-7058
-
-
David, M.1
Chen, H.E.2
Goelz, S.3
Larner, A.C.4
Neel, B.G.5
-
20
-
-
0029133702
-
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins
-
David M, Petricoin III E, Benjamin C, Pine R, Weber MJ, Larner AC. (1995b). Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. Science 269: 1721-1723.
-
(1995)
Science
, vol.269
, pp. 1721-1723
-
-
David, M.1
Petricoin III, E.2
Benjamin, C.3
Pine, R.4
Weber, M.J.5
Larner, A.C.6
-
21
-
-
0029086236
-
Characterization of active and inactive forms of the JAK2 protein-tyrosine kinase produced via the baculovirus expression vector system
-
Duhe RJ, Farrar WL. (1995). Characterization of active and inactive forms of the JAK2 protein-tyrosine kinase produced via the baculovirus expression vector system. J Biol Chem 270: 23084-23089.
-
(1995)
J Biol Chem
, vol.270
, pp. 23084-23089
-
-
Duhe, R.J.1
Farrar, W.L.2
-
22
-
-
13244254061
-
Embryonic beginnings of adult hematopoietic stem cells
-
Durand C, Dzierzak E. 2005. Embryonic beginnings of adult hematopoietic stem cells. Haematologica 90: 100-108.
-
(2005)
Haematologica
, vol.90
, pp. 100-108
-
-
Durand, C.1
Dzierzak, E.2
-
23
-
-
0028097543
-
A low affinity chimeric human alpha/beta-granulocyte-macrophage colony-stimulating factor receptor induces ligand-dependent proliferation in a murine cell line
-
Eder M, Ernst TJ, Ganser A, Jubinsky PT, Inhorn R, Hoelzer D et al. (1994). A low affinity chimeric human alpha/beta-granulocyte-macrophage colony-stimulating factor receptor induces ligand-dependent proliferation in a murine cell line. J Biol Chem 269: 30173-30180.
-
(1994)
J Biol Chem
, vol.269
, pp. 30173-30180
-
-
Eder, M.1
Ernst, T.J.2
Ganser, A.3
Jubinsky, P.T.4
Inhorn, R.5
Hoelzer, D.6
-
24
-
-
0029827828
-
Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription
-
Eilers A, Kanda K, Klose B, Krolewski J, Decker T. (1996). Constitutive STAT1 tyrosine phosphorylation in U937 monocytes overexpressing the TYK2 protein tyrosine kinase does not induce gene transcription. Cell Growth Differ 7: 833-840.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 833-840
-
-
Eilers, A.1
Kanda, K.2
Klose, B.3
Krolewski, J.4
Decker, T.5
-
25
-
-
0141561871
-
Self-renewal and lineage restriction of hematopoietic stem cells
-
Ema H, Nakauchi H. (2003). Self-renewal and lineage restriction of hematopoietic stem cells. Curr Opin Gen Dev 13: 508-512.
-
(2003)
Curr Opin Gen Dev
, vol.13
, pp. 508-512
-
-
Ema, H.1
Nakauchi, H.2
-
26
-
-
0030839112
-
A new protein containing an SH2 domain that inhibits JAK kinases
-
Endo TA, Masuhara M, Yokouchi M, Suzuki R, Sakamoto H, Mitsui K et al. (1997). A new protein containing an SH2 domain that inhibits JAK kinases. Nature 387: 921-924.
-
(1997)
Nature
, vol.387
, pp. 921-924
-
-
Endo, T.A.1
Masuhara, M.2
Yokouchi, M.3
Suzuki, R.4
Sakamoto, H.5
Mitsui, K.6
-
27
-
-
2442642830
-
Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling
-
Feener EP, Rosario F, Dunn SL, Stancheva Z, Myers Jr MG. (2004). Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling. Mol Cell Biol 24: 1968-4978.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1968-4978
-
-
Feener, E.P.1
Rosario, F.2
Dunn, S.L.3
Stancheva, Z.4
Myers Jr, M.G.5
-
28
-
-
0024989359
-
tyk2, prototype of a novel class of non-receptor tyrosine kinase genes
-
Firmbach-Kraft I, Byers M, Shows T, Dalla-Favera R, Krolewski JJ. (1990). tyk2, prototype of a novel class of non-receptor tyrosine kinase genes. Oncogene 5: 1329-1336.
-
(1990)
Oncogene
, vol.5
, pp. 1329-1336
-
-
Firmbach-Kraft, I.1
Byers, M.2
Shows, T.3
Dalla-Favera, R.4
Krolewski, J.J.5
-
29
-
-
0032536713
-
In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2
-
Flores-Morales A, Pircher TJ, Silvennoinen O, Gustafsson JA, Sanchez-Gomez M, Norstedt G et al. (1998). In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2. Mol Cell Endocrinol 138: 1-10.
-
(1998)
Mol Cell Endocrinol
, vol.138
, pp. 1-10
-
-
Flores-Morales, A.1
Pircher, T.J.2
Silvennoinen, O.3
Gustafsson, J.A.4
Sanchez-Gomez, M.5
Norstedt, G.6
-
30
-
-
0029796725
-
BCR/abl leads to the constitutive activation of Stat proteins, and shares an epitope with tyrosine phosphorylated Stats
-
Frank DA, Varticovski L. (1996). BCR/abl leads to the constitutive activation of Stat proteins, and shares an epitope with tyrosine phosphorylated Stats. Leukemia 10: 1724-1730.
-
(1996)
Leukemia
, vol.10
, pp. 1724-1730
-
-
Frank, D.A.1
Varticovski, L.2
-
31
-
-
33750221616
-
Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2
-
Funakoshi-Tago M, Pelletier S, Matsuda T, Parganas E, Ihle JN. (2006). Receptor specific downregulation of cytokine signaling by autophosphorylation in the FERM domain of Jak2. EMBO J 25: 4763-4772.
-
(2006)
EMBO J
, vol.25
, pp. 4763-4772
-
-
Funakoshi-Tago, M.1
Pelletier, S.2
Matsuda, T.3
Parganas, E.4
Ihle, J.N.5
-
32
-
-
33644990745
-
The role of protein kinase C delta activation and STAT3 Ser727 phosphorylation in insulin-induced keratinocyte proliferation
-
Gartsbein M, Alt A, Hashimoto K, Nakajima K, Kuroki T, Tennenbaum T. (2006). The role of protein kinase C delta activation and STAT3 Ser727 phosphorylation in insulin-induced keratinocyte proliferation. J Cell Sci 119: 470-481.
-
(2006)
J Cell Sci
, vol.119
, pp. 470-481
-
-
Gartsbein, M.1
Alt, A.2
Hashimoto, K.3
Nakajima, K.4
Kuroki, T.5
Tennenbaum, T.6
-
33
-
-
0030665789
-
The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor
-
Gauzzi MC, Barbieri G, Richter MF, Uz G, Ling L, Fellous M et al. (1997). The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor. Proc Natl Acad Sci USA 94: 11839-11844.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11839-11844
-
-
Gauzzi, M.C.1
Barbieri, G.2
Richter, M.F.3
Uz, G.4
Ling, L.5
Fellous, M.6
-
34
-
-
0024846310
-
Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor
-
Gearing DP, King JA, Gough NM, Nicola NA. (1989). Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor. EMBO J 8: 3667-3676.
-
(1989)
EMBO J
, vol.8
, pp. 3667-3676
-
-
Gearing, D.P.1
King, J.A.2
Gough, N.M.3
Nicola, N.A.4
-
35
-
-
31544458469
-
Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells
-
Gritsko T, Williams A, Turkson J, Kaneko S, Bowman T, Huang M et al. (2006). Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells. Clin Cancer Res 12: 11-19.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 11-19
-
-
Gritsko, T.1
Williams, A.2
Turkson, J.3
Kaneko, S.4
Bowman, T.5
Huang, M.6
-
36
-
-
0036176428
-
Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: The receptor is crucial for kinase activation
-
Haan C, Heinrich PC, Behrmann I. (2002). Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation. Biochem J 361: 105-111.
-
(2002)
Biochem J
, vol.361
, pp. 105-111
-
-
Haan, C.1
Heinrich, P.C.2
Behrmann, I.3
-
38
-
-
0032545279
-
Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction
-
Haque SJ, Harbor P, Tabrizi M, Yi T, Williams BR. (1998). Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction. J Biol Chem 273: 33893-33896.
-
(1998)
J Biol Chem
, vol.273
, pp. 33893-33896
-
-
Haque, S.J.1
Harbor, P.2
Tabrizi, M.3
Yi, T.4
Williams, B.R.5
-
39
-
-
0026735084
-
JAK2, a third member of the JAK family of protein tyrosine kinases
-
Harpur AG, Andres AC, Ziemiecki A, Aston RR, Wilks AF. (1992). JAK2, a third member of the JAK family of protein tyrosine kinases. Oncogene 7: 1347-1353.
-
(1992)
Oncogene
, vol.7
, pp. 1347-1353
-
-
Harpur, A.G.1
Andres, A.C.2
Ziemiecki, A.3
Aston, R.R.4
Wilks, A.F.5
-
40
-
-
21344435775
-
Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer
-
Haura EB, Turkson J, Jove R. (2005). Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer. Nat Clin Pract Oncol 2: 315-324.
-
(2005)
Nat Clin Pract Oncol
, vol.2
, pp. 315-324
-
-
Haura, E.B.1
Turkson, J.2
Jove, R.3
-
41
-
-
0025637605
-
Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): Reconstitution of a high-affinity GM-CSF receptor
-
Hayashida K, Kitamura T, Gorman DM, Arai K, Yokota T, Miyajima A. (1990). Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor. Proc Natl Acad Sci USA 87: 9655-9659.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 9655-9659
-
-
Hayashida, K.1
Kitamura, T.2
Gorman, D.M.3
Arai, K.4
Yokota, T.5
Miyajima, A.6
-
43
-
-
0028913109
-
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
-
Horvath CM, Wen Z, Darnell Jr JE. (1995). A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev 9: 984-994.
-
(1995)
Genes Dev
, vol.9
, pp. 984-994
-
-
Horvath, C.M.1
Wen, Z.2
Darnell Jr, J.E.3
-
44
-
-
0035694582
-
The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor
-
Huang LJ, Constantinescu SN, Lodish HF. (2001). The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor. Mol Cell Biol 8: 1327-1338.
-
(2001)
Mol Cell Biol
, vol.8
, pp. 1327-1338
-
-
Huang, L.J.1
Constantinescu, S.N.2
Lodish, H.F.3
-
45
-
-
0027914830
-
Signal transduction
-
Hunter T. (1993). Signal transduction. Cytokine Connections Nat 366: 114-116.
-
(1993)
Cytokine Connections Nat
, vol.366
, pp. 114-116
-
-
Hunter, T.1
-
46
-
-
0030704646
-
Jaks and Stats in cytokine signaling
-
discussion 112
-
Ihle JN, Nosaka T, Thierfelder W, Quelle FW, Shimoda K. (1997). Jaks and Stats in cytokine signaling. Stem Cells 15: 105-111; discussion 112.
-
(1997)
Stem Cells
, vol.15
, pp. 105-111
-
-
Ihle, J.N.1
Nosaka, T.2
Thierfelder, W.3
Quelle, F.W.4
Shimoda, K.5
-
47
-
-
0028933799
-
Signaling through the hematopoietic cytokine receptors
-
Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Silvennoinen O. (1995). Signaling through the hematopoietic cytokine receptors. Annu Rev Immunol 13: 369-398.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 369-398
-
-
Ihle, J.N.1
Witthuhn, B.A.2
Quelle, F.W.3
Yamamoto, K.4
Silvennoinen, O.5
-
48
-
-
0000506439
-
P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
-
Ilaria Jr RL, Van Etten RA. (1996). P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members. J Biol Chem 271: 31704-31710.
-
(1996)
J Biol Chem
, vol.271
, pp. 31704-31710
-
-
Ilaria Jr, R.L.1
Van Etten, R.A.2
-
49
-
-
0035905767
-
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
-
Irie-Sasaki J, Sasaki T, Matsumoto W, Opavsky A, Cheng M, Welstead G et al. (2001). CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature 409: 349-354.
-
(2001)
Nature
, vol.409
, pp. 349-354
-
-
Irie-Sasaki, J.1
Sasaki, T.2
Matsumoto, W.3
Opavsky, A.4
Cheng, M.5
Welstead, G.6
-
50
-
-
0025091768
-
Cloning of an interleukin-3 receptor gene: A member of a distinct receptor gene family
-
Itoh N, Yonehara S, Schreurs J, Gorman DM, Maruyama K, Ishii A et al. (1990). Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family. Science 247: 324-327.
-
(1990)
Science
, vol.247
, pp. 324-327
-
-
Itoh, N.1
Yonehara, S.2
Schreurs, J.3
Gorman, D.M.4
Maruyama, K.5
Ishii, A.6
-
51
-
-
0032542211
-
Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)
-
Jain N, Zhang T, Fong SL, Lim CP, Cao X. (1998). Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK). Oncogene 17: 3157-3167.
-
(1998)
Oncogene
, vol.17
, pp. 3157-3167
-
-
Jain, N.1
Zhang, T.2
Fong, S.L.3
Lim, C.P.4
Cao, X.5
-
52
-
-
0033588229
-
Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner
-
Jain N, Zhang T, Kee WH, Li W, Cao X. (1999). Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. J Biol Chem 274: 24392-24400.
-
(1999)
J Biol Chem
, vol.274
, pp. 24392-24400
-
-
Jain, N.1
Zhang, T.2
Kee, W.H.3
Li, W.4
Cao, X.5
-
53
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C, Ugo V, Le Couédic JP, Staerk J, Delhommeau F, Lacout C et al. (2005). A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 434: 1144-1148.
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couédic, J.P.3
Staerk, J.4
Delhommeau, F.5
Lacout, C.6
-
54
-
-
0029973560
-
Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1
-
Jiao H, Berrada K, Yang W, Tabrizi M, Platanias LC, Yi T. (1996). Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1. Mol Cell Biol 16: 6985-6992.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6985-6992
-
-
Jiao, H.1
Berrada, K.2
Yang, W.3
Tabrizi, M.4
Platanias, L.C.5
Yi, T.6
-
55
-
-
0027497570
-
A low-affinity human granulocyte-macrophage colony-stimulating factor/murine erythropoietin hybrid receptor functions in murine cell lines
-
Jubinsky PT, Nathan DG, Wilson DJ, Sieff CA. (1993). A low-affinity human granulocyte-macrophage colony-stimulating factor/murine erythropoietin hybrid receptor functions in murine cell lines. Blood 81: 587-591.
-
(1993)
Blood
, vol.81
, pp. 587-591
-
-
Jubinsky, P.T.1
Nathan, D.G.2
Wilson, D.J.3
Sieff, C.A.4
-
56
-
-
0034638632
-
Computational and functional analysis of the putative SH2 domain in Janus kinases
-
Kampa D, Burnside J. (2000). Computational and functional analysis of the putative SH2 domain in Janus kinases. Biochem Biophys Res Commun 278: 175-182.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 175-182
-
-
Kampa, D.1
Burnside, J.2
-
57
-
-
0028301958
-
Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes
-
Kawamura M, McVicar DW, Johnston JA, Blake TB, Chen YQ, Lal BK et al. (1994). Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes. Proc Natl Acad Sci USA 9: 6374-6378.
-
(1994)
Proc Natl Acad Sci USA
, vol.9
, pp. 6374-6378
-
-
Kawamura, M.1
McVicar, D.W.2
Johnston, J.A.3
Blake, T.B.4
Chen, Y.Q.5
Lal, B.K.6
-
58
-
-
0033529715
-
Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A
-
Kazansky AV, Kabotyanski EB, Wyszomierski SL, Mancini MA, Rosen JM. (1999). Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A. J Biol Chem 274: 22484-22492.
-
(1999)
J Biol Chem
, vol.274
, pp. 22484-22492
-
-
Kazansky, A.V.1
Kabotyanski, E.B.2
Wyszomierski, S.L.3
Mancini, M.A.4
Rosen, J.M.5
-
59
-
-
33746043322
-
The role of Janus kinases in haemapoiesis and haematological malignancy
-
Khwaja A. (2006). The role of Janus kinases in haemapoiesis and haematological malignancy. Br J Haematol 134: 366-384.
-
(2006)
Br J Haematol
, vol.134
, pp. 366-384
-
-
Khwaja, A.1
-
60
-
-
0028117163
-
Cytokine signal transduction
-
Kishimoto T, Taga T, Akira S. (1994). Cytokine signal transduction. Cell 76: 253-262.
-
(1994)
Cell
, vol.76
, pp. 253-262
-
-
Kishimoto, T.1
Taga, T.2
Akira, S.3
-
61
-
-
0037138370
-
Signaling through the JAK/STAT pathway, recent advances and future challenges
-
Kisseleva T, Bhattacharya S, Braunstein J, Schindler CW. (2002). Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285: 1-24.
-
(2002)
Gene
, vol.285
, pp. 1-24
-
-
Kisseleva, T.1
Bhattacharya, S.2
Braunstein, J.3
Schindler, C.W.4
-
62
-
-
0028956353
-
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
-
Klingmuller U, Lorenz U, Cantley LC, Neel BG, Lodish HF. (1995). Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 80: 729-738.
-
(1995)
Cell
, vol.80
, pp. 729-738
-
-
Klingmuller, U.1
Lorenz, U.2
Cantley, L.C.3
Neel, B.G.4
Lodish, H.F.5
-
63
-
-
0031039426
-
A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses
-
Kohlhuber F, Rogers NC, Watling D, Feng J, Guschin D, Briscoe J et al. (1997). A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses. Mol Cell Biol 17: 695-706.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 695-706
-
-
Kohlhuber, F.1
Rogers, N.C.2
Watling, D.3
Feng, J.4
Guschin, D.5
Briscoe, J.6
-
64
-
-
0030016180
-
Other kinases can substitute for Jak2 in signal transduction by interferon-gamma
-
Kotenko SV, Izotova LS, Pollack BP, Muthukumaran G, Paukku K, Silvennoinen O et al. (1996). Other kinases can substitute for Jak2 in signal transduction by interferon-gamma. J Biol Chem 271: 17174-17182.
-
(1996)
J Biol Chem
, vol.271
, pp. 17174-17182
-
-
Kotenko, S.V.1
Izotova, L.S.2
Pollack, B.P.3
Muthukumaran, G.4
Paukku, K.5
Silvennoinen, O.6
-
65
-
-
0030048771
-
Critical proline residues of the cytoplasmic domain of the IL-5 receptor alpha chain and its function in IL-5-mediated activation of JAK kinase and STAT5
-
Kouro T, Kikuchi Y, Kanazawa H, Hirokawa K, Harada N, Shiiba M et al. (1996). Critical proline residues of the cytoplasmic domain of the IL-5 receptor alpha chain and its function in IL-5-mediated activation of JAK kinase and STAT5. Int Immunol 8: 237-245.
-
(1996)
Int Immunol
, vol.8
, pp. 237-245
-
-
Kouro, T.1
Kikuchi, Y.2
Kanazawa, H.3
Hirokawa, K.4
Harada, N.5
Shiiba, M.6
-
66
-
-
0035862950
-
Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression
-
Kovarik P, Mangold M, Ramsauer K, Heidari H, Steinborn R, Zotter A et al. (2001). Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression. EMBO J 20: 91-100.
-
(2001)
EMBO J
, vol.20
, pp. 91-100
-
-
Kovarik, P.1
Mangold, M.2
Ramsauer, K.3
Heidari, H.4
Steinborn, R.5
Zotter, A.6
-
67
-
-
0034801684
-
SOCS proteins: Negative regulators of cytokine signaling
-
Krebs DL, Hilton DJ. (2001). SOCS proteins: negative regulators of cytokine signaling. Stem Cells 19: 378-387.
-
(2001)
Stem Cells
, vol.19
, pp. 378-387
-
-
Krebs, D.L.1
Hilton, D.J.2
-
68
-
-
0030836517
-
Kinase-deficient forms of Jak1 and Tyk2 inhibit interferon alpha signaling in a dominant manner
-
Krishnan K, Pine R, Krolewski JJ. (1997). Kinase-deficient forms of Jak1 and Tyk2 inhibit interferon alpha signaling in a dominant manner. Eur J Biochem 247: 298-305.
-
(1997)
Eur J Biochem
, vol.247
, pp. 298-305
-
-
Krishnan, K.1
Pine, R.2
Krolewski, J.J.3
-
69
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
Kralovics R, Passamonti F, Buser AS, Teo SS, Tiedt R, Passweg JR et al. (2005). A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 352: 1779-1790.
-
(2005)
N Engl J Med
, vol.352
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
Teo, S.S.4
Tiedt, R.5
Passweg, J.R.6
-
70
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ et al. (2005). Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7: 387-397.
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
Ebert, B.L.4
Wernig, G.5
Huntly, B.J.6
-
71
-
-
15844386904
-
Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells
-
Lin JX, Mietz J, Modi WS, John S, Leonard WJ. (1996). Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells. J Biol Chem 271: 10738-10744.
-
(1996)
J Biol Chem
, vol.271
, pp. 10738-10744
-
-
Lin, J.X.1
Mietz, J.2
Modi, W.S.3
John, S.4
Leonard, W.J.5
-
72
-
-
33947221062
-
T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6
-
Lu X, Chen J, Sasmono RT, Hsi ED, Sarosiek KA, Tiganis T et al. (2007). T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6. Mol Cell Biol 27: 166-179.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 166-179
-
-
Lu, X.1
Chen, J.2
Sasmono, R.T.3
Hsi, E.D.4
Sarosiek, K.A.5
Tiganis, T.6
-
73
-
-
30044437118
-
Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
-
Lu X, Levine R, Tong W, Wernig G, Pikman Y, Zarnegar S et al. (2005). Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation. Proc Natl Acad Sci USA 102: 18962-18967.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18962-18967
-
-
Lu, X.1
Levine, R.2
Tong, W.3
Wernig, G.4
Pikman, Y.5
Zarnegar, S.6
-
74
-
-
0030794017
-
The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation
-
Matsuguchi T, Zhao Y, Lilly MB, Kraft AS. (1997). The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation. J Biol Chem 272: 17450-17459.
-
(1997)
J Biol Chem
, vol.272
, pp. 17450-17459
-
-
Matsuguchi, T.1
Zhao, Y.2
Lilly, M.B.3
Kraft, A.S.4
-
75
-
-
0030956715
-
CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation
-
Matsumoto A, Masuhara M, Mitsui K, Yokouchi M, Ohtsubo M, Misawa H et al. (1997). CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood 89: 3148-3154.
-
(1997)
Blood
, vol.89
, pp. 3148-3154
-
-
Matsumoto, A.1
Masuhara, M.2
Mitsui, K.3
Yokouchi, M.4
Ohtsubo, M.5
Misawa, H.6
-
76
-
-
0032584235
-
Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells
-
Migone TS, Cacalano NA, Taylor N, Yi T, Waldmann TA, Johnston JA. (1998). Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells. Proc Natl Acad Sci USA 95: 3845-3850.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3845-3850
-
-
Migone, T.S.1
Cacalano, N.A.2
Taylor, N.3
Yi, T.4
Waldmann, T.A.5
Johnston, J.A.6
-
77
-
-
0026689408
-
Cytokine receptors and signal transduction
-
Miyajima A, Kitamura T, Harada N, Yokota T, Arai K. (1992). Cytokine receptors and signal transduction. Annu Rev Immunol 10: 295-331.
-
(1992)
Annu Rev Immunol
, vol.10
, pp. 295-331
-
-
Miyajima, A.1
Kitamura, T.2
Harada, N.3
Yokota, T.4
Arai, K.5
-
78
-
-
0029045866
-
Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5
-
Mui AL, Wakao H, Harada N, O'Farrell AM, Miyajima A. (1995a). Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5. J Leukoc Biol 57: 799-803.
-
(1995)
J Leukoc Biol
, vol.57
, pp. 799-803
-
-
Mui, A.L.1
Wakao, H.2
Harada, N.3
O'Farrell, A.M.4
Miyajima, A.5
-
79
-
-
0028963550
-
Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs
-
Mui AL, Wakao H, O'Farrell AM, Harada N, Miyajima A. (1995b). Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs. EMBO J 14: 1166-1175.
-
(1995)
EMBO J
, vol.14
, pp. 1166-1175
-
-
Mui, A.L.1
Wakao, H.2
O'Farrell, A.M.3
Harada, N.4
Miyajima, A.5
-
80
-
-
0026505476
-
Molecular cloning and expression of the human interleukin 5 receptor
-
Murata Y, Takaki S, Migita M, Kikuchi Y, Tominaga A, Takatsu K. (1992). Molecular cloning and expression of the human interleukin 5 receptor. J Exp Med 175: 341-351.
-
(1992)
J Exp Med
, vol.175
, pp. 341-351
-
-
Murata, Y.1
Takaki, S.2
Migita, M.3
Kikuchi, Y.4
Tominaga, A.5
Takatsu, K.6
-
81
-
-
33847351136
-
The JAK-STAT signaling pathway: Input and output regulation
-
Murray PJ. (2007). The JAK-STAT signaling pathway: input and output regulation. J Immunol 78: 2623-2629.
-
(2007)
J Immunol
, vol.78
, pp. 2623-2629
-
-
Murray, P.J.1
-
82
-
-
0035930501
-
TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B
-
Myers MP, Andersen JN, Cheng A, Tremblay ML, Horvath CM, Parisien JP et al. (2001). TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B. J Biol Chem 276: 47771-47774.
-
(2001)
J Biol Chem
, vol.276
, pp. 47771-47774
-
-
Myers, M.P.1
Andersen, J.N.2
Cheng, A.3
Tremblay, M.L.4
Horvath, C.M.5
Parisien, J.P.6
-
83
-
-
0030755934
-
Structure and function of a new STAT-induced STAT inhibitor
-
Naka T, Narazaki M, Hirata M, Matsumoto T, Minamoto S, Aono A et al. (1997). Structure and function of a new STAT-induced STAT inhibitor. Nature 387: 924-929.
-
(1997)
Nature
, vol.387
, pp. 924-929
-
-
Naka, T.1
Narazaki, M.2
Hirata, M.3
Matsumoto, T.4
Minamoto, S.5
Aono, A.6
-
84
-
-
0038771965
-
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
-
Neel BG, Gu H, Pao L. (2003). The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem Sci 28: 284-293.
-
(2003)
Trends Biochem Sci
, vol.28
, pp. 284-293
-
-
Neel, B.G.1
Gu, H.2
Pao, L.3
-
85
-
-
0033583530
-
Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis
-
Nieborowska-Skorska M, Wasik MA, Slupianek A, Salomoni P, Kitamura T, Calabretta B et al. (1999). Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis. J Exp Med 189: 1229-1242.
-
(1999)
J Exp Med
, vol.189
, pp. 1229-1242
-
-
Nieborowska-Skorska, M.1
Wasik, M.A.2
Slupianek, A.3
Salomoni, P.4
Kitamura, T.5
Calabretta, B.6
-
86
-
-
0035870249
-
Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest
-
Niu G, Shain KH, Huang M, Ravi R, Bedi A, Dalton WS et al. (2001). Overexpression of a dominant-negative signal transducer and activator of transcription 3 variant in tumor cells leads to production of soluble factors that induce apoptosis and cell cycle arrest. Cancer Res 61: 3276-3280.
-
(2001)
Cancer Res
, vol.61
, pp. 3276-3280
-
-
Niu, G.1
Shain, K.H.2
Huang, M.3
Ravi, R.4
Bedi, A.5
Dalton, W.S.6
-
87
-
-
0036233585
-
Cytokine signaling in 2002: NEw surprises in the Jak/Stat pathway
-
O'Shea JJ, Gadina M, Schreiber RD. (2002). Cytokine signaling in 2002: NEw surprises in the Jak/Stat pathway. Cell 109: S121-S131.
-
(2002)
Cell
, vol.109
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
89
-
-
0030804219
-
The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs)
-
Pellegrini S, Dusanter-Fourt I. 1997. The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs). Eur J Biochem 248: 615-633.
-
(1997)
Eur J Biochem
, vol.248
, pp. 615-633
-
-
Pellegrini, S.1
Dusanter-Fourt, I.2
-
90
-
-
0029133520
-
Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor
-
Quelle FW, Thierfelder W, Witthuhn BA, Tang B, Cohen S, Ihle JN. (1995). Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor. J Biol Chem 270: 20775-20780.
-
(1995)
J Biol Chem
, vol.270
, pp. 20775-20780
-
-
Quelle, F.W.1
Thierfelder, W.2
Witthuhn, B.A.3
Tang, B.4
Cohen, S.5
Ihle, J.N.6
-
91
-
-
0037415720
-
The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression
-
Ragimbeau J, Dondi E, Alcover A, Eid P, Uze G, Pellegrini S. (2003). The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression. EMBO J 22: 537-547.
-
(2003)
EMBO J
, vol.22
, pp. 537-547
-
-
Ragimbeau, J.1
Dondi, E.2
Alcover, A.3
Eid, P.4
Uze, G.5
Pellegrini, S.6
-
92
-
-
23044500093
-
Controlling cytokine signaling by constitutive inhibitors
-
Rakesh K, Agrawal DK. (2005). Controlling cytokine signaling by constitutive inhibitors. Biochem Pharmacol 70: 649-657.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 649-657
-
-
Rakesh, K.1
Agrawal, D.K.2
-
93
-
-
0028206119
-
JAK3: A novel JAK kinase associated with terminal differentiation of hematopoietic cells
-
Rane SG, Reddy EP. (1994). JAK3: a novel JAK kinase associated with terminal differentiation of hematopoietic cells. Oncogene 9: 2415-2423.
-
(1994)
Oncogene
, vol.9
, pp. 2415-2423
-
-
Rane, S.G.1
Reddy, E.P.2
-
94
-
-
0034657447
-
IL-3 signaling and the role of Src kinases, JAKs and STATs: A covert liaison unveiled
-
Reddy EP, Korapati A, Chaturvedi P, Rane S. (2000). IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled. Oncogene 19: 2532-2547.
-
(2000)
Oncogene
, vol.19
, pp. 2532-2547
-
-
Reddy, E.P.1
Korapati, A.2
Chaturvedi, P.3
Rane, S.4
-
95
-
-
0032544656
-
Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1
-
Richter MF, Duménil G, Uzé G, Fellous M, Pellegrini S. (1998). Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1. J Biol Chem 273: 24723-24729.
-
(1998)
J Biol Chem
, vol.273
, pp. 24723-24729
-
-
Richter, M.F.1
Duménil, G.2
Uzé, G.3
Fellous, M.4
Pellegrini, S.5
-
96
-
-
12844280533
-
Transcriptional regulation in myelopoiesis: Hematopoietic fate choice, myeloid differentiation, and leukemogenesis
-
Rosmarin AG, Yang Z, Resendes KK. (2005). Transcriptional regulation in myelopoiesis: hematopoietic fate choice, myeloid differentiation, and leukemogenesis. Exp Hematol 33: 131-143.
-
(2005)
Exp Hematol
, vol.33
, pp. 131-143
-
-
Rosmarin, A.G.1
Yang, Z.2
Resendes, K.K.3
-
97
-
-
0028171065
-
Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: Implications for XSCID and XCID
-
Russell SM, Johnston JA, Noguchi M, Kawamura M, Bacon CM, Friedmann M et al. (1994). Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID. Science 266: 1042-1045.
-
(1994)
Science
, vol.266
, pp. 1042-1045
-
-
Russell, S.M.1
Johnston, J.A.2
Noguchi, M.3
Kawamura, M.4
Bacon, C.M.5
Friedmann, M.6
-
98
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
-
Russell SM, Tayebi N, Nakajima H, Riedy MC, Roberts JL, Aman MJ et al. (1995). Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science 270: 797-800.
-
(1995)
Science
, vol.270
, pp. 797-800
-
-
Russell, S.M.1
Tayebi, N.2
Nakajima, H.3
Riedy, M.C.4
Roberts, J.L.5
Aman, M.J.6
-
99
-
-
0037033012
-
The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction
-
Saharinen P, Silvennoinen O. (2002). The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction. J Biol Chem 277: 47954-47963.
-
(2002)
J Biol Chem
, vol.277
, pp. 47954-47963
-
-
Saharinen, P.1
Silvennoinen, O.2
-
100
-
-
0034012330
-
Regulation of the Jak2 tyrosine kinase by its pseudokinase domain
-
Saharinen P, Takaluoma K, Silvennoinen O. (2000). Regulation of the Jak2 tyrosine kinase by its pseudokinase domain. Mol Cell Biol 20: 3387-3395.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3387-3395
-
-
Saharinen, P.1
Takaluoma, K.2
Silvennoinen, O.3
-
101
-
-
0038371050
-
Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain
-
Saharinen P, Vihinen M, Silvennoinen O. (2003). Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain. Mol Cell Biol 14: 1448-1459.
-
(2003)
Mol Cell Biol
, vol.14
, pp. 1448-1459
-
-
Saharinen, P.1
Vihinen, M.2
Silvennoinen, O.3
-
102
-
-
0029075875
-
Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3
-
Schaefer TS, Sanders LK, Nathans D. (1995). Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3. Proc Natl Acad Sci USA 92: 9097-9101.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9097-9101
-
-
Schaefer, T.S.1
Sanders, L.K.2
Nathans, D.3
-
103
-
-
0345575181
-
Cytokines and STAT signaling
-
Schindler C, Strehlow I. (2000). Cytokines and STAT signaling. Adv Pharmacol 47: 113-174.
-
(2000)
Adv Pharmacol
, vol.47
, pp. 113-174
-
-
Schindler, C.1
Strehlow, I.2
-
104
-
-
0036790814
-
Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation
-
Seki Y, Hayashi K, Matsumoto A, Seki N, Tsukada J, Ransom J et al. (2002). Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation. Proc Natl Acad Sci USA 99: 13003-13008.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13003-13008
-
-
Seki, Y.1
Hayashi, K.2
Matsumoto, A.3
Seki, N.4
Tsukada, J.5
Ransom, J.6
-
105
-
-
0036006288
-
The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3
-
Simoncic PD, Lee-Loy A, Barber DL, Tremblay ML, McGlade CJ. (2002). The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. Curr Biol 12: 446-453.
-
(2002)
Curr Biol
, vol.12
, pp. 446-453
-
-
Simoncic, P.D.1
Lee-Loy, A.2
Barber, D.L.3
Tremblay, M.L.4
McGlade, C.J.5
-
106
-
-
0031032525
-
Cytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines
-
Smith A, Metcalf D, Nicola NA. (1997). Cytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines. EMBO J 16: 451-464.
-
(1997)
EMBO J
, vol.16
, pp. 451-464
-
-
Smith, A.1
Metcalf, D.2
Nicola, N.A.3
-
107
-
-
0027328343
-
The alphas, betas, and kinases of cytokine receptor complexes
-
Stahl N, Yancopoulos GD. (1993). The alphas, betas, and kinases of cytokine receptor complexes. Cell 74: 587-590.
-
(1993)
Cell
, vol.74
, pp. 587-590
-
-
Stahl, N.1
Yancopoulos, G.D.2
-
108
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signalling
-
Starr R, Willson TA, Viney EM, Murray LJ, Rayner JR, Jenkins BJ et al. (1997). A family of cytokine-inducible inhibitors of signalling. Nature 387: 917-921.
-
(1997)
Nature
, vol.387
, pp. 917-921
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
Murray, L.J.4
Rayner, J.R.5
Jenkins, B.J.6
-
109
-
-
0028268381
-
Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases
-
Takahashi T, Shirasawa T. (1994). Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases. FEBS Lett 342: 124-128.
-
(1994)
FEBS Lett
, vol.342
, pp. 124-128
-
-
Takahashi, T.1
Shirasawa, T.2
-
110
-
-
20444476625
-
SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling
-
Tanaka T, Soriano MA, Grusby MJ. (2005). SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling. Immunity 22: 729-736.
-
(2005)
Immunity
, vol.22
, pp. 729-736
-
-
Tanaka, T.1
Soriano, M.A.2
Grusby, M.J.3
-
111
-
-
0028964465
-
Cytokine signaling through non-receptor tyrosine kinases
-
Taniguchi T. (1995). Cytokine signaling through non-receptor tyrosine kinases. Science 268: 251-255.
-
(1995)
Science
, vol.268
, pp. 251-255
-
-
Taniguchi, T.1
-
112
-
-
0036318564
-
-
ten Hoeve J, de Jesus Ibarra-Sanchez M, Fu Y, Zhu W, Tremblay M, David M et al. (2002). Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol 22: 5662-5668.
-
ten Hoeve J, de Jesus Ibarra-Sanchez M, Fu Y, Zhu W, Tremblay M, David M et al. (2002). Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol 22: 5662-5668.
-
-
-
-
113
-
-
0036233985
-
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1
-
Ungureanu D, Saharinen P, Junttila I, Hilton DJ, Silvennoinen O. (2002). Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1. Mol Cell Biol 22: 3316-3326.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3316-3326
-
-
Ungureanu, D.1
Saharinen, P.2
Junttila, I.3
Hilton, D.J.4
Silvennoinen, O.5
-
114
-
-
22044431593
-
SUMO-1 conjugation selectively modulates STAT1-mediated gene responses
-
Ungureanu D, Vanhatupa S, Gronholm J, Palvimo JJ, Silvennoinen O. (2005). SUMO-1 conjugation selectively modulates STAT1-mediated gene responses. Blood 106: 224-226.
-
(2005)
Blood
, vol.106
, pp. 224-226
-
-
Ungureanu, D.1
Vanhatupa, S.2
Gronholm, J.3
Palvimo, J.J.4
Silvennoinen, O.5
-
115
-
-
0142152429
-
PIAS proteins promote SUMO-1 conjugation to STAT1
-
Ungureanu D, Vanhatupa S, Kotaja N, Yang J, Aittomaki S, Janne OA et al. (2003). PIAS proteins promote SUMO-1 conjugation to STAT1. Blood 102: 3311-3313.
-
(2003)
Blood
, vol.102
, pp. 3311-3313
-
-
Ungureanu, D.1
Vanhatupa, S.2
Kotaja, N.3
Yang, J.4
Aittomaki, S.5
Janne, O.A.6
-
116
-
-
32144453842
-
JAK/STAT signal transduction: Regulators and implication in hematological malignancies
-
Valentino L, Pierre J. (2006). JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem Pharmacol 71: 713-721.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 713-721
-
-
Valentino, L.1
Pierre, J.2
-
117
-
-
0032561322
-
Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein
-
Verdier F, Chretien S, Muller O, Varlet P, Yoshimura A, Gisselbrecht S et al. (1998). Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein. J BiolChem 273: 28185-28190.
-
(1998)
J BiolChem
, vol.273
, pp. 28185-28190
-
-
Verdier, F.1
Chretien, S.2
Muller, O.3
Varlet, P.4
Yoshimura, A.5
Gisselbrecht, S.6
-
118
-
-
34247172195
-
Both the suppressor of cytokine signaling 1 (SOCS-1) kinase inhibitory region and SOCS-1 mimetic bind to JAK2 autophosphorylation site: Implications for the development of a SOCS-1 antagonist
-
Waiboci LW, Ahmed CM, Mujtaba MG, Flowers LO, Martin JP, Haider MI et al. (2007). Both the suppressor of cytokine signaling 1 (SOCS-1) kinase inhibitory region and SOCS-1 mimetic bind to JAK2 autophosphorylation site: implications for the development of a SOCS-1 antagonist. J Immunol 178: 5058-5068.
-
(2007)
J Immunol
, vol.178
, pp. 5058-5068
-
-
Waiboci, L.W.1
Ahmed, C.M.2
Mujtaba, M.G.3
Flowers, L.O.4
Martin, J.P.5
Haider, M.I.6
-
119
-
-
0029113153
-
Receptors for interleukin-3 (IL-3) and growth hormone mediate an IL-6-type transcriptional induction in the presence of JAK2 or STAT3
-
Wang Y, Morella KK, Ripperger J, Lai CF, Gearing DP, Fey GH et al. (1995). Receptors for interleukin-3 (IL-3) and growth hormone mediate an IL-6-type transcriptional induction in the presence of JAK2 or STAT3. Blood 86: 1671-1679.
-
(1995)
Blood
, vol.86
, pp. 1671-1679
-
-
Wang, Y.1
Morella, K.K.2
Ripperger, J.3
Lai, C.F.4
Gearing, D.P.5
Fey, G.H.6
-
120
-
-
0028332086
-
Activation and inhibition of erythropoietin receptor function: Role of receptor dimerization
-
Watowich SS, Hilton DJ, Lodish HF. (1994). Activation and inhibition of erythropoietin receptor function: role of receptor dimerization. Mol Cell Biol 14: 3535-3549.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 3535-3549
-
-
Watowich, S.S.1
Hilton, D.J.2
Lodish, H.F.3
-
121
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen Z, Zhong Z, Darnell Jr JE. (1995). Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82: 241-250.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr, J.E.3
-
122
-
-
0026081302
-
Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase
-
Wilks AF, Harpur AG, Kurban RR, Ralph SJ, Zürcher G, Ziemiecki A. (1991). Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase. Mol Cell Biol 11: 2057-2065.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 2057-2065
-
-
Wilks, A.F.1
Harpur, A.G.2
Kurban, R.R.3
Ralph, S.J.4
Zürcher, G.5
Ziemiecki, A.6
-
123
-
-
0033604519
-
Signal transduction in the erythropoietin receptor system
-
Wojchowski DM, Gregory RC, Miller CP, Pandit AK, Pircher TJ. (1999). Signal transduction in the erythropoietin receptor system. Exp Cell Res 253: 143-156.
-
(1999)
Exp Cell Res
, vol.253
, pp. 143-156
-
-
Wojchowski, D.M.1
Gregory, R.C.2
Miller, C.P.3
Pandit, A.K.4
Pircher, T.J.5
-
124
-
-
0029739627
-
Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
-
Xu X, Sun YL, Hoey T. (1996). Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain. Science 272: 794-797.
-
(1996)
Science
, vol.272
, pp. 794-797
-
-
Xu, X.1
Sun, Y.L.2
Hoey, T.3
-
125
-
-
0037047335
-
CD45 controls interleukin-4-mediated IgE class switch recombination in human B cells through its function as a Janus kinase phosphatase
-
Yamada T, Zhu D, Saxon A, Zhang K. (2002). CD45 controls interleukin-4-mediated IgE class switch recombination in human B cells through its function as a Janus kinase phosphatase. J Biol Chem 277: 28830-28835.
-
(2002)
J Biol Chem
, vol.277
, pp. 28830-28835
-
-
Yamada, T.1
Zhu, D.2
Saxon, A.3
Zhang, K.4
-
126
-
-
0028228543
-
Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation
-
Yamamoto K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, Jenkins NA et al. (1994). Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation. Mol Cell Biol 14: 4342-4349.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4342-4349
-
-
Yamamoto, K.1
Quelle, F.W.2
Thierfelder, W.E.3
Kreider, B.L.4
Gilbert, D.J.5
Jenkins, N.A.6
-
127
-
-
0027488637
-
Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis
-
Yi T, Mui AL, Krystal G, Ihle JN. (1993). Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol Cell Biol 13: 7577-7586.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7577-7586
-
-
Yi, T.1
Mui, A.L.2
Krystal, G.3
Ihle, J.N.4
-
128
-
-
0029014206
-
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
-
Yoshimura A, Ohkubo T, Kiguchi T, Jenkins NA, Gilbert DJ, Copeland NG et al. (1995). A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J 14: 2816-2826.
-
(1995)
EMBO J
, vol.14
, pp. 2816-2826
-
-
Yoshimura, A.1
Ohkubo, T.2
Kiguchi, T.3
Jenkins, N.A.4
Gilbert, D.J.5
Copeland, N.G.6
-
129
-
-
0029069540
-
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
-
Yu CL, Meyer DJ, Campbell GS, Larner AC, Carter-Su C, Schwartz J et al. (1995). Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science 269: 81-83.
-
(1995)
Science
, vol.269
, pp. 81-83
-
-
Yu, C.L.1
Meyer, D.J.2
Campbell, G.S.3
Larner, A.C.4
Carter-Su, C.5
Schwartz, J.6
-
130
-
-
0028942656
-
Requirement of serine phosphorylation for formation of STAT-promoter complexes
-
Zhang X, Blenis J, Li H, Schindler C, Chen-Kiang S. (1995). Requirement of serine phosphorylation for formation of STAT-promoter complexes. Science 267: 1990-1994.
-
(1995)
Science
, vol.267
, pp. 1990-1994
-
-
Zhang, X.1
Blenis, J.2
Li, H.3
Schindler, C.4
Chen-Kiang, S.5
|