-
1
-
-
19944427133
-
The Janus kinases
-
Yamoaka, K., P. Saharinen, M. Pesu, V. E. Holt III, O. Silvennoinen, and J. J. O'Shea. 2004. The Janus kinases. Genome Biol. 5: 253-258.
-
(2004)
Genome Biol
, vol.5
, pp. 253-258
-
-
Yamoaka, K.1
Saharinen, P.2
Pesu, M.3
Holt III, V.E.4
Silvennoinen, O.5
O'Shea, J.J.6
-
2
-
-
0032076542
-
JAK2 is essential for signaling through a variety of cytokine receptors
-
Parganas, E., D. Wang, D. J. Stravapodis, D. Topham, J. C. Marine, S. Teglund, E. F. Vanin, S. Bodner, O. Colamonici, J. M. Deursen, et al. 1998. JAK2 is essential for signaling through a variety of cytokine receptors. Cell 93: 385-395.
-
(1998)
Cell
, vol.93
, pp. 385-395
-
-
Parganas, E.1
Wang, D.2
Stravapodis, D.J.3
Topham, D.4
Marine, J.C.5
Teglund, S.6
Vanin, E.F.7
Bodner, S.8
Colamonici, O.9
Deursen, J.M.10
-
3
-
-
0035928897
-
So many ligands, so few transcription factors: A new paradigm for signaling through the STAT transcription factors
-
Subramaniam, P. S., B. A. Torres, and H. M. Johnson. 2001. So many ligands, so few transcription factors: a new paradigm for signaling through the STAT transcription factors. Cytokine 15: 175-187.
-
(2001)
Cytokine
, vol.15
, pp. 175-187
-
-
Subramaniam, P.S.1
Torres, B.A.2
Johnson, H.M.3
-
4
-
-
4644247974
-
Trafficking and signaling pathways of molecular localizing protein ligands and their receptors
-
Johnson, H. M., P. S. Subramaniam, S. Olsnes, and D. A. Jans. 2004. Trafficking and signaling pathways of molecular localizing protein ligands and their receptors. BioEssays 26: 993-1004.
-
(2004)
BioEssays
, vol.26
, pp. 993-1004
-
-
Johnson, H.M.1
Subramaniam, P.S.2
Olsnes, S.3
Jans, D.A.4
-
5
-
-
0034658583
-
JAK-STAT signal transduction pathway through the eyes of cytokine class II receptor complexes
-
Kotenko, S. V., and S. Pestka. 2000. JAK-STAT signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19: 2557-2567.
-
(2000)
Oncogene
, vol.19
, pp. 2557-2567
-
-
Kotenko, S.V.1
Pestka, S.2
-
6
-
-
0034657336
-
The role of STATs in transcriptional control and their impact on cellular function
-
Bromberg, J., and J. E. Darnell, Jr. 2000. The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19: 2468-2473.
-
(2000)
Oncogene
, vol.19
, pp. 2468-2473
-
-
Bromberg, J.1
Darnell Jr., J.E.2
-
7
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signaling
-
Starr, R., T. A. Willson, E. M. Viney, L. J. L. Murray, J. R. Rayner, B. J. Jenkins, T. J. Gonda, W. S. Alexander, D. Metcalf, N. A. Nicola, and D. J. Hilton. 1997. A family of cytokine-inducible inhibitors of signaling. Nature 387: 917-921.
-
(1997)
Nature
, vol.387
, pp. 917-921
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
Murray, L.J.L.4
Rayner, J.R.5
Jenkins, B.J.6
Gonda, T.J.7
Alexander, W.S.8
Metcalf, D.9
Nicola, N.A.10
Hilton, D.J.11
-
8
-
-
0030839112
-
A new protein containing SH2 domain that inhibits JAK kinases
-
Endo, T. A., M. Masuhara, M. Yokouchi, R. Suzuki, H. Sakamoto, K. Mitsui, A. Matsumoto, S. Tanimura, M. Ohtsubo, H. Misakawa, et al. 1997. A new protein containing SH2 domain that inhibits JAK kinases. Nature 387: 921-924.
-
(1997)
Nature
, vol.387
, pp. 921-924
-
-
Endo, T.A.1
Masuhara, M.2
Yokouchi, M.3
Suzuki, R.4
Sakamoto, H.5
Mitsui, K.6
Matsumoto, A.7
Tanimura, S.8
Ohtsubo, M.9
Misakawa, H.10
-
9
-
-
0030755934
-
I997. Structure and function of a new STAT-induced STAT inhibitor
-
Naka, T., M. Narazaki, M. Hirata, T. Matsumoto, S. Minamoto, A. Anono, N. Nashimoto, T. Kajita, T. Taga, K. Yoshizaki, et al. I997. Structure and function of a new STAT-induced STAT inhibitor. Nature 387: 924-929.
-
Nature
, vol.387
, pp. 924-929
-
-
Naka, T.1
Narazaki, M.2
Hirata, M.3
Matsumoto, T.4
Minamoto, S.5
Anono, A.6
Nashimoto, N.7
Kajita, T.8
Taga, T.9
Yoshizaki, K.10
-
10
-
-
0036595049
-
Suppressors of cytokine signaling (SOCS) in the immune system
-
Alexander, W. S. 2002. Suppressors of cytokine signaling (SOCS) in the immune system. Nat. Rev. Immunol. 2: 410-416.
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 410-416
-
-
Alexander, W.S.1
-
11
-
-
0036986179
-
Suppressors of cytokine signaling: SOCS
-
Larsen, L., and C. Röpke. 2002. Suppressors of cytokine signaling: SOCS. APMIS 110: 833-844.
-
(2002)
APMIS
, vol.110
, pp. 833-844
-
-
Larsen, L.1
Röpke, C.2
-
12
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of immune responses
-
Alexander, W. S., and D. J. Hilton. 2004. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of immune responses. Annu. Rev. Immunol. 22: 503-529.
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
13
-
-
0242285719
-
STAT proteins: From normal control of cellular events to tumorigenesis
-
Calo, V., M. Migliavacca, V. Bazan, M. Macaluso, M. Busemi, N. Gebba, and A. Russo. 2003. STAT proteins: from normal control of cellular events to tumorigenesis. J. Cell. Physiol. 197: 157-168.
-
(2003)
J. Cell. Physiol
, vol.197
, pp. 157-168
-
-
Calo, V.1
Migliavacca, M.2
Bazan, V.3
Macaluso, M.4
Busemi, M.5
Gebba, N.6
Russo, A.7
-
14
-
-
2942615015
-
Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function
-
Flowers, L. O., H. M. Johnson, M. G. Mujtaba, M. R. Ellis, S. M. Haider, and P. S. Subramaniam. 2004. Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function. J. Immunol. 172: 7510-7518.
-
(2004)
J. Immunol
, vol.172
, pp. 7510-7518
-
-
Flowers, L.O.1
Johnson, H.M.2
Mujtaba, M.G.3
Ellis, M.R.4
Haider, S.M.5
Subramaniam, P.S.6
-
15
-
-
20244389693
-
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
-
Yasukawa, H., H. Misawa, H. Sakamoto, M. Masuhara, A. Sasaki, T. Wakioka, S. Ohtsuka, T. Imaizumi, T. Matsuda, J. N. Ihle, and A. Yoshimura. 1999. The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop. EMBO J. 18: 1309-1320.
-
(1999)
EMBO J
, vol.18
, pp. 1309-1320
-
-
Yasukawa, H.1
Misawa, H.2
Sakamoto, H.3
Masuhara, M.4
Sasaki, A.5
Wakioka, T.6
Ohtsuka, S.7
Imaizumi, T.8
Matsuda, T.9
Ihle, J.N.10
Yoshimura, A.11
-
16
-
-
16444371427
-
A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells
-
Flowers, L. O., P. S. Subramaniam, and H. M. Johnson. 2005. A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells. Oncogene 24: 2114-2120.
-
(2005)
Oncogene
, vol.24
, pp. 2114-2120
-
-
Flowers, L.O.1
Subramaniam, P.S.2
Johnson, H.M.3
-
17
-
-
26844548688
-
Treatment of mice with the suppressor of cytokine signaling-1 peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form
-
Mujtaba, M. G., L. O. Flowers, C. B. Patel, R. A. Patel, M. I. Haider, and H. M. Johnson. 2005. Treatment of mice with the suppressor of cytokine signaling-1 peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form. J. Immunol. 175: 5077-5086.
-
(2005)
J. Immunol
, vol.175
, pp. 5077-5086
-
-
Mujtaba, M.G.1
Flowers, L.O.2
Patel, C.B.3
Patel, R.A.4
Haider, M.I.5
Johnson, H.M.6
-
18
-
-
0029959155
-
Structural requirements for agonist activity of a murine interferon γ peptide
-
Szente, B. E., I. J. Weiner, M. J. Jablonsky, N. R. Krishna, B. A. Torres, and H. M. Johnson. 1996. Structural requirements for agonist activity of a murine interferon γ peptide. J. Interferon Cytokine Res. 16: 813-817.
-
(1996)
J. Interferon Cytokine Res
, vol.16
, pp. 813-817
-
-
Szente, B.E.1
Weiner, I.J.2
Jablonsky, M.J.3
Krishna, N.R.4
Torres, B.A.5
Johnson, H.M.6
-
19
-
-
0019759682
-
Viral plaque-reduction assay for interferon: Microplaque and regular macroplaque reduction assay
-
Langford, M. P., D. A. Weiget, G. J. Stanton, and S. Baron. 1981. Viral plaque-reduction assay for interferon: microplaque and regular macroplaque reduction assay. Methods Enzymol. 78: 339-349.
-
(1981)
Methods Enzymol
, vol.78
, pp. 339-349
-
-
Langford, M.P.1
Weiget, D.A.2
Stanton, G.J.3
Baron, S.4
-
20
-
-
0035818573
-
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo
-
Zhang, J., G. D. Metcalf, S. Rakar, M. Asimakis, C. J. Greenhalgh, T. A. Willson, R. Starr, S. E. Nicholson, W. Carter, W. S. Alexander, et al. 2001. The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo. Proc. Natl. Acad. Sci. USA 98: 13261-13265.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13261-13265
-
-
Zhang, J.1
Metcalf, G.D.2
Rakar, S.3
Asimakis, M.4
Greenhalgh, C.J.5
Willson, T.A.6
Starr, R.7
Nicholson, S.E.8
Carter, W.9
Alexander, W.S.10
-
21
-
-
0030890586
-
Cellular responses to interferon γ
-
Boehn, U., T. Klamp, M. Groot, and J. C. Howar. 1997. Cellular responses to interferon γ. Annu. Rev. Immunol. 15: 749-795.
-
(1997)
Annu. Rev. Immunol
, vol.15
, pp. 749-795
-
-
Boehn, U.1
Klamp, T.2
Groot, M.3
Howar, J.C.4
-
22
-
-
0033539052
-
IFNγ-derived lipopeptide: Influence of lipid modification on the conformation and the ability to induce MHC class II expression on marine and human cells
-
Thiam, K., E. Long, C. Verwaerde, C. Auriault, and H. Gras-Masse. 1999. IFNγ-derived lipopeptide: influence of lipid modification on the conformation and the ability to induce MHC class II expression on marine and human cells. J. Med. Chem. 42: 3732-3736.
-
(1999)
J. Med. Chem
, vol.42
, pp. 3732-3736
-
-
Thiam, K.1
Long, E.2
Verwaerde, C.3
Auriault, C.4
Gras-Masse, H.5
-
23
-
-
33748789628
-
The interferon γ mimetic peptide IFN-γ(95-133) prevents encephalomyocarditis virus infection both in tissue culture and in mice
-
Mujtaba, M. G., C. B. Patel, R. A. Patel, L. O. Flowers, M. A. Burkhat, L. W. Waiboci, J. P. Martin, M. I. Haider, C. M. Ahmed, and H. M. Johnson. 2006. The interferon γ mimetic peptide IFN-γ(95-133) prevents encephalomyocarditis virus infection both in tissue culture and in mice. Clin. Vaccine Immunol. 13: 944-952.
-
(2006)
Clin. Vaccine Immunol
, vol.13
, pp. 944-952
-
-
Mujtaba, M.G.1
Patel, C.B.2
Patel, R.A.3
Flowers, L.O.4
Burkhat, M.A.5
Waiboci, L.W.6
Martin, J.P.7
Haider, M.I.8
Ahmed, C.M.9
Johnson, H.M.10
-
24
-
-
0037927824
-
c-dependent cytokines in peripheral T cells
-
c-dependent cytokines in peripheral T cells. J. Biol. Chem. 278: 22755-22761.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 22755-22761
-
-
Cornish, A.L.1
Chong, M.M.2
Davey, G.M.3
Darwiche, R.4
Nicola, N.A.5
Hilton, D.J.6
Kay, T.W.7
Starr, R.8
Alexander, W.S.9
-
25
-
-
0037138370
-
Signaling through the JAK/STAT pathway, recent advances and future challenges
-
Kisseleva, T., S. Bhattacharya, J. Braunstein, and C. W. Schindler. 2002. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285: 1-25.
-
(2002)
Gene
, vol.285
, pp. 1-25
-
-
Kisseleva, T.1
Bhattacharya, S.2
Braunstein, J.3
Schindler, C.W.4
-
26
-
-
0041677606
-
Principles of interleukin (IL)-6 type cytokine signaling and regulation
-
Heinrich, P. C., I. Behrmann, S. Haan, H. M. Hermanns, G. Muller-Newen, and F. Schaper. 2003. Principles of interleukin (IL)-6 type cytokine signaling and regulation. Biochem. J. 374: 1-20.
-
(2003)
Biochem. J
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
Behrmann, I.2
Haan, S.3
Hermanns, H.M.4
Muller-Newen, G.5
Schaper, F.6
-
27
-
-
11144254962
-
Silencing SOCS-1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity
-
Shen, L., K. Evel-Kabler, R. Strube, and S. Y. Chen. 2004. Silencing SOCS-1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity. Nat. Biotechnol. 22: 1546-1553.
-
(2004)
Nat. Biotechnol
, vol.22
, pp. 1546-1553
-
-
Shen, L.1
Evel-Kabler, K.2
Strube, R.3
Chen, S.Y.4
-
28
-
-
0033520326
-
SOCS-1 is a critical inhibitor of interferon γ signaling and prevents potentially fatal neonatal actions of this cytokine
-
Alexander, W. S., R. Starr, J. E. Fenner, C. L. Scott, E. Handman, N. S. Sprigg, J. E. Corbin, A. L. Cornish, R. Darwiche, C. M. Owczarek, et al. 1999. SOCS-1 is a critical inhibitor of interferon γ signaling and prevents potentially fatal neonatal actions of this cytokine. Cell 98: 597-608.
-
(1999)
Cell
, vol.98
, pp. 597-608
-
-
Alexander, W.S.1
Starr, R.2
Fenner, J.E.3
Scott, C.L.4
Handman, E.5
Sprigg, N.S.6
Corbin, J.E.7
Cornish, A.L.8
Darwiche, R.9
Owczarek, C.M.10
-
29
-
-
23944480863
-
Negative regulation of cytokine signaling
-
Yoshimura, A. 2005. Negative regulation of cytokine signaling. Clin. Rev. Allergy Immunol. 28: 205-220.
-
(2005)
Clin. Rev. Allergy Immunol
, vol.28
, pp. 205-220
-
-
Yoshimura, A.1
-
30
-
-
0032850616
-
Interferon activation of STAT6 by interleukin-4 in human monocytes by induction of SOCS-1 gene expression
-
Dickensheets, H. L., C. Venkataraman, U. Schindler, and R. P. Donnelly. 1999. Interferon activation of STAT6 by interleukin-4 in human monocytes by induction of SOCS-1 gene expression. Proc. Natl. Acad. Sci. USA 96: 10800-10805.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10800-10805
-
-
Dickensheets, H.L.1
Venkataraman, C.2
Schindler, U.3
Donnelly, R.P.4
-
31
-
-
0035933805
-
Suppressor of cytokine signaling-1 attenuates the duration of interferon γ signal transduction in vitro and in vivo
-
Brysha, M., J. G. Zhang, P. Bertolino, J. E. Corbin, W. S. Alexander, N. A. Nicola, D. J. Hilton, and R. Starr. 2001. Suppressor of cytokine signaling-1 attenuates the duration of interferon γ signal transduction in vitro and in vivo. J. Biol. Chem. 276: 22086-22089.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 22086-22089
-
-
Brysha, M.1
Zhang, J.G.2
Bertolino, P.3
Corbin, J.E.4
Alexander, W.S.5
Nicola, N.A.6
Hilton, D.J.7
Starr, R.8
-
32
-
-
0037992519
-
Rational design of peptide vaccines for autoimmune disease: Harnessing molecular recognition to fix a broken network
-
Weathington, N. M., and J. E. Blalock. 2003. Rational design of peptide vaccines for autoimmune disease: harnessing molecular recognition to fix a broken network. Expert Rev. Vaccines 2: 61-73.
-
(2003)
Expert Rev. Vaccines
, vol.2
, pp. 61-73
-
-
Weathington, N.M.1
Blalock, J.E.2
|