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Volumn 178, Issue 8, 2007, Pages 5058-5068

Both the suppressor of cytokine signaling 1 (SOCS-1) kinase inhibitory region and SOCS-1 mimetic bind to JAK2 autophosphorylation site: Implications for the development of a SOCS-1 antagonist

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 6; JANUS KINASE 2; PROTEIN TKIP; PROTEIN TYROSINE KINASE INHIBITOR; STAT1 ALPHA PROTEIN; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING 1 ANTAGONIST; TYROSINE; UNCLASSIFIED DRUG;

EID: 34247172195     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.8.5058     Document Type: Article
Times cited : (99)

References (32)
  • 3
    • 0035928897 scopus 로고    scopus 로고
    • So many ligands, so few transcription factors: A new paradigm for signaling through the STAT transcription factors
    • Subramaniam, P. S., B. A. Torres, and H. M. Johnson. 2001. So many ligands, so few transcription factors: a new paradigm for signaling through the STAT transcription factors. Cytokine 15: 175-187.
    • (2001) Cytokine , vol.15 , pp. 175-187
    • Subramaniam, P.S.1    Torres, B.A.2    Johnson, H.M.3
  • 4
    • 4644247974 scopus 로고    scopus 로고
    • Trafficking and signaling pathways of molecular localizing protein ligands and their receptors
    • Johnson, H. M., P. S. Subramaniam, S. Olsnes, and D. A. Jans. 2004. Trafficking and signaling pathways of molecular localizing protein ligands and their receptors. BioEssays 26: 993-1004.
    • (2004) BioEssays , vol.26 , pp. 993-1004
    • Johnson, H.M.1    Subramaniam, P.S.2    Olsnes, S.3    Jans, D.A.4
  • 5
    • 0034658583 scopus 로고    scopus 로고
    • JAK-STAT signal transduction pathway through the eyes of cytokine class II receptor complexes
    • Kotenko, S. V., and S. Pestka. 2000. JAK-STAT signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19: 2557-2567.
    • (2000) Oncogene , vol.19 , pp. 2557-2567
    • Kotenko, S.V.1    Pestka, S.2
  • 6
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • Bromberg, J., and J. E. Darnell, Jr. 2000. The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19: 2468-2473.
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell Jr., J.E.2
  • 10
    • 0036595049 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling (SOCS) in the immune system
    • Alexander, W. S. 2002. Suppressors of cytokine signaling (SOCS) in the immune system. Nat. Rev. Immunol. 2: 410-416.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 410-416
    • Alexander, W.S.1
  • 11
    • 0036986179 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling: SOCS
    • Larsen, L., and C. Röpke. 2002. Suppressors of cytokine signaling: SOCS. APMIS 110: 833-844.
    • (2002) APMIS , vol.110 , pp. 833-844
    • Larsen, L.1    Röpke, C.2
  • 12
    • 2542478996 scopus 로고    scopus 로고
    • The role of suppressors of cytokine signaling (SOCS) proteins in regulation of immune responses
    • Alexander, W. S., and D. J. Hilton. 2004. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of immune responses. Annu. Rev. Immunol. 22: 503-529.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 503-529
    • Alexander, W.S.1    Hilton, D.J.2
  • 14
    • 2942615015 scopus 로고    scopus 로고
    • Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function
    • Flowers, L. O., H. M. Johnson, M. G. Mujtaba, M. R. Ellis, S. M. Haider, and P. S. Subramaniam. 2004. Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function. J. Immunol. 172: 7510-7518.
    • (2004) J. Immunol , vol.172 , pp. 7510-7518
    • Flowers, L.O.1    Johnson, H.M.2    Mujtaba, M.G.3    Ellis, M.R.4    Haider, S.M.5    Subramaniam, P.S.6
  • 16
    • 16444371427 scopus 로고    scopus 로고
    • A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells
    • Flowers, L. O., P. S. Subramaniam, and H. M. Johnson. 2005. A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells. Oncogene 24: 2114-2120.
    • (2005) Oncogene , vol.24 , pp. 2114-2120
    • Flowers, L.O.1    Subramaniam, P.S.2    Johnson, H.M.3
  • 17
    • 26844548688 scopus 로고    scopus 로고
    • Treatment of mice with the suppressor of cytokine signaling-1 peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form
    • Mujtaba, M. G., L. O. Flowers, C. B. Patel, R. A. Patel, M. I. Haider, and H. M. Johnson. 2005. Treatment of mice with the suppressor of cytokine signaling-1 peptide, tyrosine kinase inhibitor peptide, prevents development of the acute form of experimental allergic encephalomyelitis and induces stable remission in the chronic relapsing/remitting form. J. Immunol. 175: 5077-5086.
    • (2005) J. Immunol , vol.175 , pp. 5077-5086
    • Mujtaba, M.G.1    Flowers, L.O.2    Patel, C.B.3    Patel, R.A.4    Haider, M.I.5    Johnson, H.M.6
  • 19
    • 0019759682 scopus 로고
    • Viral plaque-reduction assay for interferon: Microplaque and regular macroplaque reduction assay
    • Langford, M. P., D. A. Weiget, G. J. Stanton, and S. Baron. 1981. Viral plaque-reduction assay for interferon: microplaque and regular macroplaque reduction assay. Methods Enzymol. 78: 339-349.
    • (1981) Methods Enzymol , vol.78 , pp. 339-349
    • Langford, M.P.1    Weiget, D.A.2    Stanton, G.J.3    Baron, S.4
  • 22
    • 0033539052 scopus 로고    scopus 로고
    • IFNγ-derived lipopeptide: Influence of lipid modification on the conformation and the ability to induce MHC class II expression on marine and human cells
    • Thiam, K., E. Long, C. Verwaerde, C. Auriault, and H. Gras-Masse. 1999. IFNγ-derived lipopeptide: influence of lipid modification on the conformation and the ability to induce MHC class II expression on marine and human cells. J. Med. Chem. 42: 3732-3736.
    • (1999) J. Med. Chem , vol.42 , pp. 3732-3736
    • Thiam, K.1    Long, E.2    Verwaerde, C.3    Auriault, C.4    Gras-Masse, H.5
  • 25
    • 0037138370 scopus 로고    scopus 로고
    • Signaling through the JAK/STAT pathway, recent advances and future challenges
    • Kisseleva, T., S. Bhattacharya, J. Braunstein, and C. W. Schindler. 2002. Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285: 1-25.
    • (2002) Gene , vol.285 , pp. 1-25
    • Kisseleva, T.1    Bhattacharya, S.2    Braunstein, J.3    Schindler, C.W.4
  • 27
    • 11144254962 scopus 로고    scopus 로고
    • Silencing SOCS-1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity
    • Shen, L., K. Evel-Kabler, R. Strube, and S. Y. Chen. 2004. Silencing SOCS-1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity. Nat. Biotechnol. 22: 1546-1553.
    • (2004) Nat. Biotechnol , vol.22 , pp. 1546-1553
    • Shen, L.1    Evel-Kabler, K.2    Strube, R.3    Chen, S.Y.4
  • 29
    • 23944480863 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling
    • Yoshimura, A. 2005. Negative regulation of cytokine signaling. Clin. Rev. Allergy Immunol. 28: 205-220.
    • (2005) Clin. Rev. Allergy Immunol , vol.28 , pp. 205-220
    • Yoshimura, A.1
  • 30
    • 0032850616 scopus 로고    scopus 로고
    • Interferon activation of STAT6 by interleukin-4 in human monocytes by induction of SOCS-1 gene expression
    • Dickensheets, H. L., C. Venkataraman, U. Schindler, and R. P. Donnelly. 1999. Interferon activation of STAT6 by interleukin-4 in human monocytes by induction of SOCS-1 gene expression. Proc. Natl. Acad. Sci. USA 96: 10800-10805.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10800-10805
    • Dickensheets, H.L.1    Venkataraman, C.2    Schindler, U.3    Donnelly, R.P.4
  • 31
    • 0035933805 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 attenuates the duration of interferon γ signal transduction in vitro and in vivo
    • Brysha, M., J. G. Zhang, P. Bertolino, J. E. Corbin, W. S. Alexander, N. A. Nicola, D. J. Hilton, and R. Starr. 2001. Suppressor of cytokine signaling-1 attenuates the duration of interferon γ signal transduction in vitro and in vivo. J. Biol. Chem. 276: 22086-22089.
    • (2001) J. Biol. Chem , vol.276 , pp. 22086-22089
    • Brysha, M.1    Zhang, J.G.2    Bertolino, P.3    Corbin, J.E.4    Alexander, W.S.5    Nicola, N.A.6    Hilton, D.J.7    Starr, R.8
  • 32
    • 0037992519 scopus 로고    scopus 로고
    • Rational design of peptide vaccines for autoimmune disease: Harnessing molecular recognition to fix a broken network
    • Weathington, N. M., and J. E. Blalock. 2003. Rational design of peptide vaccines for autoimmune disease: harnessing molecular recognition to fix a broken network. Expert Rev. Vaccines 2: 61-73.
    • (2003) Expert Rev. Vaccines , vol.2 , pp. 61-73
    • Weathington, N.M.1    Blalock, J.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.