Identification of a nuclear Stat1 protein tyrosine phosphatase

Molecular and Cellular Biology

Volumn 22, Issue 16, 2002, Pages 5662-5668

  Ten Hoeve, Johanna ^a   Ibarra Sanchez, Maria de Jesus ^a   Fu, Yubin ^a   Zhu, Wei ^a   Tremblay, Michel ^a   David, Michael ^a   Shuai, Ke ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; PROTEIN TYROSINE PHOSPHATASE; STAT1 PROTEIN; STAT5 PROTEIN; STAT6 PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DEPHOSPHORYLATION; ELECTROPHORESIS; ENDOPLASMIC RETICULUM; FIBROBLAST; GENE TRANSLOCATION; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; THYMOCYTE; TRANSCRIPTION INITIATION;

ANIMALS; CELL FRACTIONATION; CELL LINE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FIBROBLASTS; HUMANS; INTERFERON TYPE II; INTERLEUKIN-2; ISOENZYMES; MICE; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAUROSPORINE; T-LYMPHOCYTES; THYMUS GLAND; TRANS-ACTIVATORS;

ANIMALIA;

EID: 0036318564     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.16.5662-5668.2002     Document Type: Article

References (36)

1. A cytosolic protein-tyrosine phosphatase PTPIB specifically dephosphorylates and deactivates prolactin-activated STAT5a and STAT5h
2. A nuclear protein tyrosine phosphatase TC-PTP is potential negative regulator of the PRL-mediated signaling pathway: Dephosphorylation and deactivation of signal transducer and activator of transcription 5a and 5b by TC-PTP in nucleus
3. Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain
4. STATs in oncogenesis
5. Interleukin-3-induced activation of the JAK/STAT pathway is prolonged by proteasome inhibitors
6. Activation of transcription via AP-1 or CREB regulatory sites is blocked by protein tyrosine phosphatases
7. cDNA isolated from human T-cell library encodes a member of the protein-tyrosine-phosphatase family
8. STATs and gene regulation
9. A nuclear tyrosine phosphatase downregulates interferon-induced gene expression
10. Accurate transcription initiation, by RNA polymerase II in a soluble extract from isolated mammalian nuclei
11. Targeted disruption of the mouse Stat1 gene result, in compromised innate immunity to viral disease
12. A nuclear protein, tyrosine phosphatase is required for the inactivation of Stat1
13. The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
14. Negative regulators of cytokine signal transduction
15. The T-cell protein tyrosine phosphatase
16. Murine embryonic fibroblasts lacking TC-PTP display delayed GI phase through defective NF-kappaB activation
17. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
18. High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors
19. Cellular stress regulates the nucleocytoplasmic distribution of the protein tyrosine phosphatase TCPTP
20. Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity
21. COOH-terminal sequence motifs target the T cell protein tyrosine phosphatase to the ER and nucleus
22. Nuclear export signal located within the DNA-binding domain of the STAT1 transcription factor
23. TYK2 and JAK2 are substrates of protein-tyrosine phosphatase IB
24. Production of high-titer helper-free retroviruses by transient transfection
25. Modulation of STAT signaling by STAT-interacting proteins
26. Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1
27. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
28. The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3
29. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
30. shc are specific substrates of T-cell protein tyrosine phosphatase
31. The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling
32. Combinatorial control of the specificity of protein tyrosine phosphatases
33. The Jak-Stat pathway in normal and perturbed hematopoiesis
34. Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice
35. Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation
36. Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation