Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 20, 2002, Pages 13003-13008

  Seki, Yoh Ichi ^a   Hayashi, Katsuhiko ^a   Matsumoto, Akira ^a,b   Seki, Noriyasu ^a   Tsukada, Jun ^a   Ransom, John ^c   Naka, Tetsuji ^d   Kishimoto, Tadamitsu ^e   Yoshimura, Akihiko ^b   Kubo, Masato ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c Novasite Pharmaceuticals Inc   (United States)

^d OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 4; INTERLEUKIN RECEPTOR; JANUS KINASE; PROTEIN; PROTEIN SOCS5; STAT6 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL; TRANSGENIC MOUSE;

ANIMALS; BLOTTING, NORTHERN; CELL DIFFERENTIATION; CELL LINE; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLUTATHIONE TRANSFERASE; INTERLEUKIN-4; LUCIFERASES; MICE; PHOSPHORYLATION; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEINS; RECEPTORS, INTERLEUKIN-4; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TH1 CELLS; TH2 CELLS; TIME FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSGENES;

ANIMALIA; JANUS; MUS MUSCULUS;

EID: 0036790814     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.202477099     Document Type: Article

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