Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression

EMBO Journal

Volumn 20, Issue 1-2, 2001, Pages 91-100

  Kovarik, Pavel ^a   Mangold, Monika ^a   Ramsauer, Katrin ^a   Heidari, Hamid ^a   Steinborn, Ralf ^b   Zotter, Angelika ^a   Levy, David E ^c   Müller, Mathias ^b   Decker, Thomas ^a  

^a Vienna Biocenter   (Austria)

^b UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Phosphorylation; Signal transduction; STAT1; Transcription

Indexed keywords

GAMMA INTERFERON; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; STAT1 PROTEIN; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION REGULATION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

3T3 CELLS; ANIMALS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; INTERFERON-GAMMA, RECOMBINANT; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; SERINE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION; ULTRAVIOLET RAYS;

EID: 0035862950     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.1.91     Document Type: Article

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