-
1
-
-
0028070714
-
Functional role of type I and type II interferons in antiviral defense
-
Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, Aguet M. Functional role of type I and type II interferons in antiviral defense. Science 1994; 264: 1918-1921
-
(1994)
Science
, vol.264
, pp. 1918-1921
-
-
Muller, U.1
Steinhoff, U.2
Reis, L.F.3
Hemmi, S.4
Pavlovic, J.5
Zinkernagel, R.M.6
Aguet, M.7
-
2
-
-
11144240264
-
Inverse interference: How viruses fight the interferon system
-
Weber F, Kochs G, Haller O. Inverse interference: how viruses fight the interferon system. Viral Immunol 2004; 17: 498-515
-
(2004)
Viral Immunol
, vol.17
, pp. 498-515
-
-
Weber, F.1
Kochs, G.2
Haller, O.3
-
3
-
-
0037371835
-
Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency
-
Dupuis S, Jouanguy E, Al-Hajjar S, Fieschi C, Al-Mohsen IZ, Al-Jumaah S, Yang K, Chapgier A, Eidenschenk C, Eid P, Al Ghonaium A, Tufenkeji H, Frayha H, Al-Gazlan S, Al-Rayes H, Schreiber RD, Gresser I, Casanova JL. Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency. Nat Genet 2003; 33: 388-391
-
(2003)
Nat Genet
, vol.33
, pp. 388-391
-
-
Dupuis, S.1
Jouanguy, E.2
Al-Hajjar, S.3
Fieschi, C.4
Al-Mohsen, I.Z.5
Al-Jumaah, S.6
Yang, K.7
Chapgier, A.8
Eidenschenk, C.9
Eid, P.10
Al Ghonaium, A.11
Tufenkeji, H.12
Frayha, H.13
Al-Gazlan, S.14
Al-Rayes, H.15
Schreiber, R.D.16
Gresser, I.17
Casanova, J.L.18
-
4
-
-
29144501207
-
The interferon response circuit: Induction and suppression by pathogenic viruses
-
Haller O, Kochs G, Weber F. The interferon response circuit: induction and suppression by pathogenic viruses. Virology 2006; 344: 119-130
-
(2006)
Virology
, vol.344
, pp. 119-130
-
-
Haller, O.1
Kochs, G.2
Weber, F.3
-
5
-
-
0034767753
-
Antiviral actions of interferons
-
Samuel CE. Antiviral actions of interferons. Clin Microbiol Rev 2001; 14: 778-809
-
(2001)
Clin Microbiol Rev
, vol.14
, pp. 778-809
-
-
Samuel, C.E.1
-
6
-
-
0031657551
-
How cells respond to interferons
-
Stark GR, Kerr IM, Williams BR, Silverman RH, Schreiber RD. How cells respond to interferons. Annu Rev Biochem 1998; 67: 227-264
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.3
Silverman, R.H.4
Schreiber, R.D.5
-
7
-
-
0642307729
-
Evolution of the interferon tau genes and their promoters, and maternal-trophoblast interactions in control of their expression
-
Roberts RM, Ezashi T, Rosenfeld CS, Ealy AD, Kubisch HM. Evolution of the interferon tau genes and their promoters, and maternal-trophoblast interactions in control of their expression. Reprod Suppl 2003; 61: 239-251
-
(2003)
Reprod Suppl
, vol.61
, pp. 239-251
-
-
Roberts, R.M.1
Ezashi, T.2
Rosenfeld, C.S.3
Ealy, A.D.4
Kubisch, H.M.5
-
8
-
-
3242677843
-
Characterization of the murine alpha interferon gene family
-
van Pesch V, Lanaya H, Renauld JC, Michiels T. Characterization of the murine alpha interferon gene family. J Virol 2004; 78: 8219-8228
-
(2004)
J Virol
, vol.78
, pp. 8219-8228
-
-
van Pesch, V.1
Lanaya, H.2
Renauld, J.C.3
Michiels, T.4
-
9
-
-
0032538891
-
Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
-
Marie I, Durbin JE, Levy DE. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J 1998; 17: 6660-6669
-
(1998)
EMBO J
, vol.17
, pp. 6660-6669
-
-
Marie, I.1
Durbin, J.E.2
Levy, D.E.3
-
10
-
-
0036604972
-
Interferon-producing cells: On the front line in immune responses against pathogens
-
Colonna M, Krug A, Cella M. Interferon-producing cells: on the front line in immune responses against pathogens. Curr Opin Immunol 2002; 14: 373-379
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 373-379
-
-
Colonna, M.1
Krug, A.2
Cella, M.3
-
11
-
-
0042307304
-
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers
-
Diebold SS, Montoya M, Unger H, Alexopoulou L, Roy P, Haswell LE, Al-Shamkhani A, Flavell R, Borrow P, Reis e Sousa C. Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature 2003; 424: 324-328
-
(2003)
Nature
, vol.424
, pp. 324-328
-
-
Diebold, S.S.1
Montoya, M.2
Unger, H.3
Alexopoulou, L.4
Roy, P.5
Haswell, L.E.6
Al-Shamkhani, A.7
Flavell, R.8
Borrow, P.9
Reis10
Sousa, C.11
-
12
-
-
33947518195
-
RIG-I: Tri-ing to discriminate between self and non-self RNA
-
Bowie AG, Fitzgerald KA. RIG-I: tri-ing to discriminate between self and non-self RNA. Trends Immunol 2007; 28: 147-150
-
(2007)
Trends Immunol
, vol.28
, pp. 147-150
-
-
Bowie, A.G.1
Fitzgerald, K.A.2
-
13
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004; 5: 730-737
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
-
14
-
-
10344259136
-
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter
-
Andrejeva J, Childs KS, Young DF, Carlos TS, Stock N, Goodbourn S, Randall RE. The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc Natl Acad Sci USA 2004; 101: 17264-17269
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17264-17269
-
-
Andrejeva, J.1
Childs, K.S.2
Young, D.F.3
Carlos, T.S.4
Stock, N.5
Goodbourn, S.6
Randall, R.E.7
-
15
-
-
22544455673
-
Cell type-specific involvement of RIG-I in antiviral response
-
Kato H, Sato S, Yoneyama M, Yamamoto M, Uematsu S, Matsui K, Tsujimura T, Takeda K, Fujita T, Takeuchi O, Akira S. Cell type-specific involvement of RIG-I in antiviral response. Immunity 2005; 23: 19-28
-
(2005)
Immunity
, vol.23
, pp. 19-28
-
-
Kato, H.1
Sato, S.2
Yoneyama, M.3
Yamamoto, M.4
Uematsu, S.5
Matsui, K.6
Tsujimura, T.7
Takeda, K.8
Fujita, T.9
Takeuchi, O.10
Akira, S.11
-
16
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E, Loo YM, Gale M Jr, Akira S, Yonehara S, Kato A, Fujita T. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 2005; 175: 2851-2858
-
(2005)
J Immunol
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
Taira, K.6
Foy, E.7
Loo, Y.M.8
Gale Jr, M.9
Akira, S.10
Yonehara, S.11
Kato, A.12
Fujita, T.13
-
17
-
-
34447560071
-
Function of RIG-I-like receptors in antiviral innate immunity
-
Yoneyama M, Fujita T. Function of RIG-I-like receptors in antiviral innate immunity. J Biol Chem 2007; 282: 15315-15318
-
(2007)
J Biol Chem
, vol.282
, pp. 15315-15318
-
-
Yoneyama, M.1
Fujita, T.2
-
18
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005; 437: 1167-1172
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
Bartenschlager, R.6
Tschopp, J.7
-
19
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 2005; 6: 981-988
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
Kato, H.6
Ishii, K.J.7
Takeuchi, O.8
Akira, S.9
-
20
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
-
Seth RB, Sun L, Ea CK, Chen ZJ. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 2005; 122: 669-682
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.K.3
Chen, Z.J.4
-
21
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IEN-beta signaling
-
Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. VISA is an adapter protein required for virus-triggered IEN-beta signaling. Mol Cell 2005; 19: 727-740
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.G.1
Wang, Y.Y.2
Han, K.J.3
Li, L.Y.4
Zhai, Z.5
Shu, H.B.6
-
22
-
-
0038393016
-
IKKepsion and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. IKKepsion and TBK1 are essential components of the IRF3 signaling pathway. Nat Immunol 2003; 4: 491-496
-
(2003)
Nat Immunol
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.M.8
Maniatis, T.9
-
23
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK-related pathway
-
Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science 2003; 300: 1148-1151
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
tenOever, B.R.2
Grandvaux, N.3
Zhou, G.P.4
Lin, R.5
Hiscott, J.6
-
24
-
-
34447499052
-
Triggering the innate antiviral response through IRF-3 activation
-
Hiscott J. Triggering the innate antiviral response through IRF-3 activation. J Biol Chem 2007; 282: 15325-15329
-
(2007)
J Biol Chem
, vol.282
, pp. 15325-15329
-
-
Hiscott, J.1
-
25
-
-
0037151040
-
Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex
-
Suhara W, Yoneyama M, Kitabayashi I, Fujita T. Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex. J Biol Chem 2002; 277: 22304-22313
-
(2002)
J Biol Chem
, vol.277
, pp. 22304-22313
-
-
Suhara, W.1
Yoneyama, M.2
Kitabayashi, I.3
Fujita, T.4
-
26
-
-
0033680737
-
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
-
Sato M, Suemori H, Hata N, Asagiri M, Ogasawara K, Nakao K, Nakaya T, Katsuki M, Noguchi S, Tanaka N, Taniguchi T. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 2000; 13: 539-548
-
(2000)
Immunity
, vol.13
, pp. 539-548
-
-
Sato, M.1
Suemori, H.2
Hata, N.3
Asagiri, M.4
Ogasawara, K.5
Nakao, K.6
Nakaya, T.7
Katsuki, M.8
Noguchi, S.9
Tanaka, N.10
Taniguchi, T.11
-
27
-
-
0035047145
-
Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: Common and unique pathways
-
Iwamura T, Yoneyama M, Yamaguchi K, Suhara W, Mori W, Shiota K, Okabe Y, Namiki H, Fujita T. Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways. Genes Cells 2001; 6: 375-388
-
(2001)
Genes Cells
, vol.6
, pp. 375-388
-
-
Iwamura, T.1
Yoneyama, M.2
Yamaguchi, K.3
Suhara, W.4
Mori, W.5
Shiota, K.6
Okabe, Y.7
Namiki, H.8
Fujita, T.9
-
28
-
-
4544222882
-
Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity
-
tenOever BR, Sharma S, Zou W, Sun Q, Grandvaux N, Julkunen I, Hemmi H, Yamamoto M, Akira S, Yeh WC, Lin R, Hiscott J. Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity. J Virol 2004; 78: 10636-10649
-
(2004)
J Virol
, vol.78
, pp. 10636-10649
-
-
tenOever, B.R.1
Sharma, S.2
Zou, W.3
Sun, Q.4
Grandvaux, N.5
Julkunen, I.6
Hemmi, H.7
Yamamoto, M.8
Akira, S.9
Yeh, W.C.10
Lin, R.11
Hiscott, J.12
-
29
-
-
0035937802
-
IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein
-
Smith EJ, Marie I, Prakash A, Garcia-Sastre A, Levy DE. IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein. J Biol Chem 2001; 276: 8951-8957
-
(2001)
J Biol Chem
, vol.276
, pp. 8951-8957
-
-
Smith, E.J.1
Marie, I.2
Prakash, A.3
Garcia-Sastre, A.4
Levy, D.E.5
-
30
-
-
0032434924
-
Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
-
Sato M, Hata N, Asagiri M, Nakaya T, Taniguchi T, Tanaka N. Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7. FEBS Lett 1998; 441: 106-110
-
(1998)
FEBS Lett
, vol.441
, pp. 106-110
-
-
Sato, M.1
Hata, N.2
Asagiri, M.3
Nakaya, T.4
Taniguchi, T.5
Tanaka, N.6
-
31
-
-
0033257795
-
JNK2 and IKKbeta are required for activating the innate response to viral infection
-
Chu WM, Ostertag D, Li ZW, Chang L, Chen Y, Hu Y, Williams B, Perrault J, Karin M. JNK2 and IKKbeta are required for activating the innate response to viral infection. Immunity 1999; 11: 721-731
-
(1999)
Immunity
, vol.11
, pp. 721-731
-
-
Chu, W.M.1
Ostertag, D.2
Li, Z.W.3
Chang, L.4
Chen, Y.5
Hu, Y.6
Williams, B.7
Perrault, J.8
Karin, M.9
-
32
-
-
0029590069
-
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase
-
Yang YL, Reis LF, Pavlovic J, Aguzzi A, Schafer R, Kumar A, Williams BR, Aguet M, Weissmann C. Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase. EMBO J 1995; 14: 6095-6106
-
(1995)
EMBO J
, vol.14
, pp. 6095-6106
-
-
Yang, Y.L.1
Reis, L.F.2
Pavlovic, J.3
Aguzzi, A.4
Schafer, R.5
Kumar, A.6
Williams, B.R.7
Aguet, M.8
Weissmann, C.9
-
33
-
-
33646453915
-
Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses
-
Weber F, Wagner V, Rasmussen SB, Hartmann R, Paludan SR. Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses. J Virol 2006; 80: 5059-5064
-
(2006)
J Virol
, vol.80
, pp. 5059-5064
-
-
Weber, F.1
Wagner, V.2
Rasmussen, S.B.3
Hartmann, R.4
Paludan, S.R.5
-
34
-
-
33750976374
-
5′-Triphosphate RNA is the ligand for RIG-I
-
Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G. 5′-Triphosphate RNA is the ligand for RIG-I. Science 2006; 314: 994-997
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
Kato, H.6
Poeck, H.7
Akira, S.8
Conzelmann, K.K.9
Schlee, M.10
Endres, S.11
Hartmann, G.12
-
35
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates
-
Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, Weber F, Reis e Sousa C. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 2006; 314: 997-1001
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Naslund, T.I.4
Liljestrom, P.5
Weber, F.6
Reis7
Sousa, C.8
-
36
-
-
34547157869
-
Cytosolic 5′-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response
-
Plumet S, Herschke F, Bourhis JM, Valentin H, Longhi S, Gerlier D. Cytosolic 5′-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon response. PLoS ONE 2007; 2: e279
-
(2007)
PLoS ONE
, vol.2
-
-
Plumet, S.1
Herschke, F.2
Bourhis, J.M.3
Valentin, H.4
Longhi, S.5
Gerlier, D.6
-
37
-
-
3142654210
-
Inferences, questions and possibilities in Toll-like receptor signalling
-
Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature 2004; 430: 257-263
-
(2004)
Nature
, vol.430
, pp. 257-263
-
-
Beutler, B.1
-
38
-
-
16844379118
-
The role of Toll-like receptors in the host response to viruses
-
Bowie AG, Haga IR. The role of Toll-like receptors in the host response to viruses. Mol Immunol 2005; 42: 859-867
-
(2005)
Mol Immunol
, vol.42
, pp. 859-867
-
-
Bowie, A.G.1
Haga, I.R.2
-
39
-
-
34447505084
-
Toll-like receptors and Type I interferons
-
Uematsu S, Akira S. Toll-like receptors and Type I interferons. J Biol Chem 2007; 282: 15319-15323
-
(2007)
J Biol Chem
, vol.282
, pp. 15319-15323
-
-
Uematsu, S.1
Akira, S.2
-
40
-
-
20044382430
-
Toll-like receptor 3 promotes cross-priming to virus-infected cells
-
Schulz O, Diebold SS, Chen M, Naslund TI, Nolte MA, Alexopoulou L, Azuma YT, Flavell RA, Liljestrom P, Reis e Sousa C. Toll-like receptor 3 promotes cross-priming to virus-infected cells. Nature 2005; 433: 887-892
-
(2005)
Nature
, vol.433
, pp. 887-892
-
-
Schulz, O.1
Diebold, S.S.2
Chen, M.3
Naslund, T.I.4
Nolte, M.A.5
Alexopoulou, L.6
Azuma, Y.T.7
Flavell, R.A.8
Liljestrom, P.9
Reis10
Sousa, C.11
-
41
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5: 987-995
-
(2004)
Nat Immunol
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
42
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001; 413: 732-738
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
43
-
-
0037407691
-
Activation with CpG-A and CpG-B oigonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells
-
Kerkmann M, Rothenfusser S, Hornung V, Towarowski A, Wagner M, Sarris A, Giese T, Endres S, Hartmann G. Activation with CpG-A and CpG-B oigonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J Immunol 2003; 170: 4465-4474
-
(2003)
J Immunol
, vol.170
, pp. 4465-4474
-
-
Kerkmann, M.1
Rothenfusser, S.2
Hornung, V.3
Towarowski, A.4
Wagner, M.5
Sarris, A.6
Giese, T.7
Endres, S.8
Hartmann, G.9
-
44
-
-
21444443078
-
Tissue-specific positive feedback requirements for production of type I interferon following virus infection
-
Prakash A, Smith E, Lee CK, Levy DE. Tissue-specific positive feedback requirements for production of type I interferon following virus infection. J Biol Chem 2005; 280: 18651-18657
-
(2005)
J Biol Chem
, vol.280
, pp. 18651-18657
-
-
Prakash, A.1
Smith, E.2
Lee, C.K.3
Levy, D.E.4
-
45
-
-
17844380477
-
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
-
Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, Takaoka A, Taya C, Taniguchi T. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 2005; 434: 1035-1040
-
(2005)
Nature
, vol.434
, pp. 1035-1040
-
-
Honda, K.1
Ohba, Y.2
Yanai, H.3
Negishi, H.4
Mizutani, T.5
Takaoka, A.6
Taya, C.7
Taniguchi, T.8
-
46
-
-
0036731485
-
Stats: Transcriptional control and biological impact
-
Levy DE, Darnell JE Jr. Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002; 3: 651-662
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 651-662
-
-
Levy, D.E.1
Darnell Jr, J.E.2
-
47
-
-
0346121599
-
Suppressors of cytokine signaling and immunity
-
Kubo M, Hanada T, Yoshimura A. Suppressors of cytokine signaling and immunity. Nat Immunol 2003; 4: 1169-1176
-
(2003)
Nat Immunol
, vol.4
, pp. 1169-1176
-
-
Kubo, M.1
Hanada, T.2
Yoshimura, A.3
-
48
-
-
23444461182
-
Regulation of gene-activation pathways by PIAS proteins in the immune system
-
Shuai K, Liu B. Regulation of gene-activation pathways by PIAS proteins in the immune system. Nat Rev Immunol 2005; 5: 593-605
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 593-605
-
-
Shuai, K.1
Liu, B.2
-
49
-
-
0034994484
-
Immunological response to interferon-gamma priming prior to interferon-alpha treatment in refractory chronic hepatitis C in relation to viral clearance
-
Katayama K, Kasahara A, Sasaki Y, Kashiwagi T, Naito M, Masuzawa M, Katoh M, Yoshihara H, Kamada T, Mukuda T, Hijioka T, Hori M, Hayashi N. Immunological response to interferon-gamma priming prior to interferon-alpha treatment in refractory chronic hepatitis C in relation to viral clearance. J Viral Hepat 2001; 8: 180-185
-
(2001)
J Viral Hepat
, vol.8
, pp. 180-185
-
-
Katayama, K.1
Kasahara, A.2
Sasaki, Y.3
Kashiwagi, T.4
Naito, M.5
Masuzawa, M.6
Katoh, M.7
Yoshihara, H.8
Kamada, T.9
Mukuda, T.10
Hijioka, T.11
Hori, M.12
Hayashi, N.13
-
50
-
-
11844269964
-
Enhancement of antiviral activity against hepatitis C virus in vitro by interferon combination therapy
-
Okuse C, Rinaudo JA, Farrar K, Wells F, Korba BE. Enhancement of antiviral activity against hepatitis C virus in vitro by interferon combination therapy. Antiviral Res 2005; 65: 23-34
-
(2005)
Antiviral Res
, vol.65
, pp. 23-34
-
-
Okuse, C.1
Rinaudo, J.A.2
Farrar, K.3
Wells, F.4
Korba, B.E.5
-
51
-
-
0034977353
-
Functional classification of interferon-stimulated genes identified using microarrays
-
de Veer MJ, Holko M, Frevel M, Walker E, Der S, Paranjape JM, Silverman RH, Williams BR. Functional classification of interferon-stimulated genes identified using microarrays. J Leukoc Biol 2001; 69: 912-920
-
(2001)
J Leukoc Biol
, vol.69
, pp. 912-920
-
-
de Veer, M.J.1
Holko, M.2
Frevel, M.3
Walker, E.4
Der, S.5
Paranjape, J.M.6
Silverman, R.H.7
Williams, B.R.8
-
52
-
-
0032417696
-
Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
-
Der SD, Zhou A, Williams BR, Silverman RH. Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc Natl Acad Sci USA 1998; 95: 15623-15628
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15623-15628
-
-
Der, S.D.1
Zhou, A.2
Williams, B.R.3
Silverman, R.H.4
-
53
-
-
0034888396
-
Effect of alpha interferon on the hepatitis C virus replicon
-
Guo JT, Bichko VV, Seeger C. Effect of alpha interferon on the hepatitis C virus replicon. J Virol 2001; 75: 8516-8523
-
(2001)
J Virol
, vol.75
, pp. 8516-8523
-
-
Guo, J.T.1
Bichko, V.V.2
Seeger, C.3
-
54
-
-
0035065277
-
Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway
-
Frese M, Pietschmann T, Moradpour D, Haller O, Bartenschlager R. Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway. J Gen Virol 2001; 82: 723-733
-
(2001)
J Gen Virol
, vol.82
, pp. 723-733
-
-
Frese, M.1
Pietschmann, T.2
Moradpour, D.3
Haller, O.4
Bartenschlager, R.5
-
55
-
-
0037007105
-
Regulation of PKR and IRF-1 during hepatitis C virus RNA replication
-
Pflugheber J, Fredericksen B, Sumpter R Jr, Wang C, Ware F, Sodora DL, Gale M Jr. Regulation of PKR and IRF-1 during hepatitis C virus RNA replication. Proc Natl Acad Sci USA 2002; 99: 4650-4655
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4650-4655
-
-
Pflugheber, J.1
Fredericksen, B.2
Sumpter Jr, R.3
Wang, C.4
Ware, F.5
Sodora, D.L.6
Gale Jr., M.7
-
56
-
-
18144401994
-
New antiviral pathway that mediates hepatitis C virus replicon Interferon sensitivity through ADAR1
-
Taylor DR, Puig M, Darnell ME, Mihalik K, Feinstone SM. New antiviral pathway that mediates hepatitis C virus replicon Interferon sensitivity through ADAR1. J Virol 2005; 79: 6291-6298
-
(2005)
J Virol
, vol.79
, pp. 6291-6298
-
-
Taylor, D.R.1
Puig, M.2
Darnell, M.E.3
Mihalik, K.4
Feinstone, S.M.5
-
57
-
-
3042660285
-
Mechanism of the interferon alpha response against hepatitis C virus replicons
-
Guo JT, Sohn JA, Zhu Q, Seeger C. Mechanism of the interferon alpha response against hepatitis C virus replicons. Virology 2004; 325: 71-81
-
(2004)
Virology
, vol.325
, pp. 71-81
-
-
Guo, J.T.1
Sohn, J.A.2
Zhu, Q.3
Seeger, C.4
-
58
-
-
0037379437
-
Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication
-
Wang C, Pflugheber J, Sumpter R Jr, Sodora DL, Hui D, Sen GC, Gale M Jr. Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication. J Virol 2003; 77: 3898-3912
-
(2003)
J Virol
, vol.77
, pp. 3898-3912
-
-
Wang, C.1
Pflugheber, J.2
Sumpter Jr, R.3
Sodora, D.L.4
Hui, D.5
Sen, G.C.6
Gale Jr., M.7
-
59
-
-
0033230617
-
PKR; a sentinel kinase for cellular stress
-
Williams BR. PKR; a sentinel kinase for cellular stress. Oncogene 1999; 18: 6112-6120
-
(1999)
Oncogene
, vol.18
, pp. 6112-6120
-
-
Williams, B.R.1
-
60
-
-
0027931663
-
Fascination with 2-5A-dependent RNase: A unique enzyme that functions in interferon action
-
Silverman RH. Fascination with 2-5A-dependent RNase: a unique enzyme that functions in interferon action. J Interferon Res 1994; 14: 101-104
-
(1994)
J Interferon Res
, vol.14
, pp. 101-104
-
-
Silverman, R.H.1
-
61
-
-
0030817251
-
Interferon action and apoptosis are defective in mice devoid of 2′,5′-oligoadenylate-dependent RNase L
-
Zhou A, Paranjape J, Brown TL, Nie H, Naik S, Dong B, Chang A, Trapp B, Fairchild R, Colmenares C, Silverman RH. Interferon action and apoptosis are defective in mice devoid of 2′,5′-oligoadenylate-dependent RNase L. EMBO J 1997; 16: 6355-6363
-
(1997)
EMBO J
, vol.16
, pp. 6355-6363
-
-
Zhou, A.1
Paranjape, J.2
Brown, T.L.3
Nie, H.4
Naik, S.5
Dong, B.6
Chang, A.7
Trapp, B.8
Fairchild, R.9
Colmenares, C.10
Silverman, R.H.11
-
62
-
-
0141891214
-
Viral stress-inducible protein p56 inhibits translation by blocking the Interaction of eIF3 with the ternary complex eIF2.GTP.Met-tRNAi
-
Hui DJ, Bhasker CR, Merrick WC, Sen GC. Viral stress-inducible protein p56 inhibits translation by blocking the Interaction of eIF3 with the ternary complex eIF2.GTP.Met-tRNAi. J Biol Chem 2003; 278: 39477-39482
-
(2003)
J Biol Chem
, vol.278
, pp. 39477-39482
-
-
Hui, D.J.1
Bhasker, C.R.2
Merrick, W.C.3
Sen, G.C.4
-
63
-
-
23944441780
-
Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54
-
Terenzi F, Pal S, Sen GC. Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54. Virology 2005; 340: 116-124
-
(2005)
Virology
, vol.340
, pp. 116-124
-
-
Terenzi, F.1
Pal, S.2
Sen, G.C.3
-
64
-
-
13944253573
-
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I
-
Sumpter R Jr, Loo YM, Foy E, Li K, Yoneyama M, Fujita T, Lemon SM, Gale M Jr. Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I. J Virol 2005; 79: 2689-2699
-
(2005)
J Virol
, vol.79
, pp. 2689-2699
-
-
Sumpter Jr, R.1
Loo, Y.M.2
Foy, E.3
Li, K.4
Yoneyama, M.5
Fujita, T.6
Lemon, S.M.7
Gale Jr., M.8
-
65
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med 2004; 10: 1366-1373
-
(2004)
Nat Med
, vol.10
, pp. 1366-1373
-
-
Wang, T.1
Town, T.2
Alexopoulou, L.3
Anderson, J.F.4
Fikrig, E.5
Flavell, R.A.6
-
66
-
-
33750813795
-
Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition
-
Wang JP, Liu P, Latz E, Golenbock DT, Finberg RW, Libraty DH. Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition. J Immunol 2006; 177: 7114-7121
-
(2006)
J Immunol
, vol.177
, pp. 7114-7121
-
-
Wang, J.P.1
Liu, P.2
Latz, E.3
Golenbock, D.T.4
Finberg, R.W.5
Libraty, D.H.6
-
67
-
-
32444441329
-
Activation of anti-hepatitis C virus responses via Toll-like receptor 7
-
Lee J, Wu CC, Lee KJ, Chuang TH, Katakura K, Liu YT, Chan M, Tawatao R, Chung M, Shen C, Cottam HB, Lai MM, Raz E, Carson DA. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc Natl Acad Sci USA 2006; 103: 1828-1833
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1828-1833
-
-
Lee, J.1
Wu, C.C.2
Lee, K.J.3
Chuang, T.H.4
Katakura, K.5
Liu, Y.T.6
Chan, M.7
Tawatao, R.8
Chung, M.9
Shen, C.10
Cottam, H.B.11
Lai, M.M.12
Raz, E.13
Carson, D.A.14
-
68
-
-
23944485662
-
Evasion of intracellular host defence by hepatitis C virus
-
Gale M Jr, Foy EM. Evasion of intracellular host defence by hepatitis C virus. Nature 2005; 436: 939-945
-
(2005)
Nature
, vol.436
, pp. 939-945
-
-
Gale Jr, M.1
Foy, E.M.2
-
69
-
-
32644490562
-
A target on the move: Innate and adaptive immune escape strategies of hepatitis C virus
-
Thimme R, Lohmann V, Weber F. A target on the move: innate and adaptive immune escape strategies of hepatitis C virus. Antiviral Res 2006; 69: 129-141
-
(2006)
Antiviral Res
, vol.69
, pp. 129-141
-
-
Thimme, R.1
Lohmann, V.2
Weber, F.3
-
70
-
-
15244346528
-
Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsion
-
Breiman A, Grandvaux N, Lin R, Ottone C, Akira S, Yoneyama M, Fujita T, Hiscott J, Meurs EF. Inhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsion. J Virol 2005; 79: 3969-3978
-
(2005)
J Virol
, vol.79
, pp. 3969-3978
-
-
Breiman, A.1
Grandvaux, N.2
Lin, R.3
Ottone, C.4
Akira, S.5
Yoneyama, M.6
Fujita, T.7
Hiscott, J.8
Meurs, E.F.9
-
71
-
-
14544280209
-
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
-
Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M Jr, Lemon SM. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci USA 2005; 102: 2992-2997
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 2992-2997
-
-
Li, K.1
Foy, E.2
Ferreon, J.C.3
Nakamura, M.4
Ferreon, A.C.5
Ikeda, M.6
Ray, S.C.7
Gale Jr, M.8
Lemon, S.M.9
-
72
-
-
0037687422
-
Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease
-
Foy E, Li K, Wang C, Sumpter R Jr, Ikeda M, Lemon SM, Gale M Jr. Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science 2003; 300: 1145-1148
-
(2003)
Science
, vol.300
, pp. 1145-1148
-
-
Foy, E.1
Li, K.2
Wang, C.3
Sumpter Jr, R.4
Ikeda, M.5
Lemon, S.M.6
Gale Jr., M.7
-
73
-
-
17844395681
-
Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses
-
Otsuka M, Kato N, Moriyama M, Taniguchi H, Wang Y, Dharel N, Kawabe T, Omata M. Interaction between the HCV NS3 protein and the host TBK1 protein leads to inhibition of cellular antiviral responses. Hepatology 2005; 41: 1004-1012
-
(2005)
Hepatology
, vol.41
, pp. 1004-1012
-
-
Otsuka, M.1
Kato, N.2
Moriyama, M.3
Taniguchi, H.4
Wang, Y.5
Dharel, N.6
Kawabe, T.7
Omata, M.8
-
74
-
-
0032824134
-
Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway
-
Heim MH, Moradpour D, Blum HE. Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway. J Virol 1999; 73: 8469-8475
-
(1999)
J Virol
, vol.73
, pp. 8469-8475
-
-
Heim, M.H.1
Moradpour, D.2
Blum, H.E.3
-
75
-
-
3042740355
-
Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs
-
Melen K, Fagerlund R, Nyqvist M, Keskinen P, Julkunen I. Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs. J Med Virol 2004; 73: 536-547
-
(2004)
J Med Virol
, vol.73
, pp. 536-547
-
-
Melen, K.1
Fagerlund, R.2
Nyqvist, M.3
Keskinen, P.4
Julkunen, I.5
-
76
-
-
34548304715
-
Activation of endoplasmic reticulum stress response by hepatitis viruses upregulates protein phosphatase 2A
-
Christen V, Treves S, Duong FH, Heim MH. Activation of endoplasmic reticulum stress response by hepatitis viruses upregulates protein phosphatase 2A. Hepatology 2007; 46: 558-565
-
(2007)
Hepatology
, vol.46
, pp. 558-565
-
-
Christen, V.1
Treves, S.2
Duong, F.H.3
Heim, M.H.4
-
77
-
-
0346100572
-
Hepatitis C virus inhibits interferon signaling through upregulation of protein phosphatase 2A
-
Duong FH, Filipowicz M, Tripodi M, La Monica N, Heim MH. Hepatitis C virus inhibits interferon signaling through upregulation of protein phosphatase 2A. Gastroenterology 2004; 126: 263-277
-
(2004)
Gastroenterology
, vol.126
, pp. 263-277
-
-
Duong, F.H.1
Filipowicz, M.2
Tripodi, M.3
La Monica, N.4
Heim, M.H.5
-
78
-
-
11144342298
-
Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes
-
de Lucas S, Bartolome J, Carreno V. Hepatitis C virus core protein down-regulates transcription of interferon-induced antiviral genes. J Infect Dis 2005; 191: 93-99
-
(2005)
J Infect Dis
, vol.191
, pp. 93-99
-
-
de Lucas, S.1
Bartolome, J.2
Carreno, V.3
-
79
-
-
0037362931
-
IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3
-
Bode JG, Ludwig S, Ehrhardt C, Albrecht U, Erhardt A, Schaper F, Heinrich PC, Haussinger D. IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3. FASEB J 2003; 17: 488-490
-
(2003)
FASEB J
, vol.17
, pp. 488-490
-
-
Bode, J.G.1
Ludwig, S.2
Ehrhardt, C.3
Albrecht, U.4
Erhardt, A.5
Schaper, F.6
Heinrich, P.C.7
Haussinger, D.8
-
80
-
-
4544336360
-
Hepatitis C virus NS5A: Tales of a promiscuous protein
-
Macdonald A, Harris M. Hepatitis C virus NS5A: tales of a promiscuous protein. J Gen Virol 2004; 85: 2485-2502
-
(2004)
J Gen Virol
, vol.85
, pp. 2485-2502
-
-
Macdonald, A.1
Harris, M.2
-
81
-
-
0029161576
-
Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region
-
Enomoto N, Sakuma I, Asahina Y, Kurosaki M, Murakami T, Yamamoto C, Izumu N, Marumo F, Sato C. Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region. J Clin Invest 1995; 96: 224-230
-
(1995)
J Clin Invest
, vol.96
, pp. 224-230
-
-
Enomoto, N.1
Sakuma, I.2
Asahina, Y.3
Kurosaki, M.4
Murakami, T.5
Yamamoto, C.6
Izumu, N.7
Marumo, F.8
Sato, C.9
-
82
-
-
9144257569
-
Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection
-
Enomoto N, Sakuma I, Asahina Y, Kurosaki M, Murakami T, Yamamoto C, Ogura Y, Izumi N, Marumo F, Sato C. Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection. N Engl J Med 1996; 334: 77-81
-
(1996)
N Engl J Med
, vol.334
, pp. 77-81
-
-
Enomoto, N.1
Sakuma, I.2
Asahina, Y.3
Kurosaki, M.4
Murakami, T.5
Yamamoto, C.6
Ogura, Y.7
Izumi, N.8
Marumo, F.9
Sato, C.10
-
83
-
-
0035215781
-
Statistical analysis of combined substitutions in nonstructural 5A region of hepatitis C virus and interferon response
-
Witherell GW, Beineke P. Statistical analysis of combined substitutions in nonstructural 5A region of hepatitis C virus and interferon response. J Med Virol 2001; 63: 8-16
-
(2001)
J Med Virol
, vol.63
, pp. 8-16
-
-
Witherell, G.W.1
Beineke, P.2
-
84
-
-
17144463221
-
Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: Molecular mechanisms of kinase regulation
-
Gale M Jr, Blakely CM, Kwieciszewski B, Tan SL, Dossett M, Tang NM, Korth MJ, Polyak SJ, Gretch DR, Katze MG. Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Mol Cell Biol 1998; 18: 5208-5218
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5208-5218
-
-
Gale Jr, M.1
Blakely, C.M.2
Kwieciszewski, B.3
Tan, S.L.4
Dossett, M.5
Tang, N.M.6
Korth, M.J.7
Polyak, S.J.8
Gretch, D.R.9
Katze, M.G.10
-
85
-
-
0034536332
-
Suppression of interferon-induced antiviral activity in cells expressing hepatitis C virus proteins
-
Aizaki H, Saito S, Ogino T, Miyajima N, Harada T, Matsuura Y, Miyamura T, Kohase M. Suppression of interferon-induced antiviral activity in cells expressing hepatitis C virus proteins. J Interferon Cytokine Res 2000; 20: 1111-1120
-
(2000)
J Interferon Cytokine Res
, vol.20
, pp. 1111-1120
-
-
Aizaki, H.1
Saito, S.2
Ogino, T.3
Miyajima, N.4
Harada, T.5
Matsuura, Y.6
Miyamura, T.7
Kohase, M.8
-
86
-
-
18844369121
-
Nonstructural protein 5A does not contribute to the resistance of hepatitis C virus replication to interferon alpha in cell culture
-
Aus dem Siepen M, Lohmann V, Wiese M, Ross S, Roggendorf M, Viazov S. Nonstructural protein 5A does not contribute to the resistance of hepatitis C virus replication to interferon alpha in cell culture. Virology 2005; 336: 131-136
-
(2005)
Virology
, vol.336
, pp. 131-136
-
-
Aus dem Siepen, M.1
Lohmann, V.2
Wiese, M.3
Ross, S.4
Roggendorf, M.5
Viazov, S.6
-
87
-
-
0032738989
-
Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response
-
Paterson M, Laxton CD, Thomas HC, Ackrill AM, Foster GR. Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response. Gastroenterology 1999; 117: 1187-1197
-
(1999)
Gastroenterology
, vol.117
, pp. 1187-1197
-
-
Paterson, M.1
Laxton, C.D.2
Thomas, H.C.3
Ackrill, A.M.4
Foster, G.R.5
-
88
-
-
0242422098
-
Expression of hepatitis C virus proteins interferes with the antiviral action of interferon independently of PKR-mediated control of protein synthesis
-
Francois C, Duverlie G, Rebouillat D, Khorsi H, Castelain S, Blum HE, Gatignol A, Wychowski C, Moradpour D, Meurs EF. Expression of hepatitis C virus proteins interferes with the antiviral action of interferon independently of PKR-mediated control of protein synthesis. J Virol 2000; 74: 5587-5596
-
(2000)
J Virol
, vol.74
, pp. 5587-5596
-
-
Francois, C.1
Duverlie, G.2
Rebouillat, D.3
Khorsi, H.4
Castelain, S.5
Blum, H.E.6
Gatignol, A.7
Wychowski, C.8
Moradpour, D.9
Meurs, E.F.10
-
89
-
-
0034992398
-
Expression of hepatitis C virus NS5A natural mutants in a hepatocytic cell line inhibits the antiviral effect of interferon in a PKR-independent manner
-
Podevin P, Sabile A, Gajardo R, Delhem N, Abadie A, Lozach PY, Beretta L, Brechot C. Expression of hepatitis C virus NS5A natural mutants in a hepatocytic cell line inhibits the antiviral effect of interferon in a PKR-independent manner. Hepatology 2001; 33: 1503-1511
-
(2001)
Hepatology
, vol.33
, pp. 1503-1511
-
-
Podevin, P.1
Sabile, A.2
Gajardo, R.3
Delhem, N.4
Abadie, A.5
Lozach, P.Y.6
Beretta, L.7
Brechot, C.8
-
90
-
-
0034623816
-
Efficient initiation of HCV RNA replication in cell culture
-
Blight KJ, Kolykhalov AA, Rice CM. Efficient initiation of HCV RNA replication in cell culture. Science 2000; 290: 1972-1974
-
(2000)
Science
, vol.290
, pp. 1972-1974
-
-
Blight, K.J.1
Kolykhalov, A.A.2
Rice, C.M.3
-
91
-
-
13944263525
-
Mutational analysis of hepatitis C virus nonstructural protein 5A: Potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain
-
Appel N, Pietschmann T, Bartenschlager R. Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain. J Virol 2005; 79: 3187-3194
-
(2005)
J Virol
, vol.79
, pp. 3187-3194
-
-
Appel, N.1
Pietschmann, T.2
Bartenschlager, R.3
-
92
-
-
0034969251
-
Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response
-
Polyak SJ, Khabar KS, Paschal DM, Ezelle HJ, Duverlie G, Barber GN, Levy DE, Mukaida N, Gretch DR. Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. J Virol 2001; 75: 6095-6106
-
(2001)
J Virol
, vol.75
, pp. 6095-6106
-
-
Polyak, S.J.1
Khabar, K.S.2
Paschal, D.M.3
Ezelle, H.J.4
Duverlie, G.5
Barber, G.N.6
Levy, D.E.7
Mukaida, N.8
Gretch, D.R.9
-
93
-
-
0034979117
-
Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy
-
Polyak SJ, Khabar KS, Rezeiq M, Gretch DR. Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy. J Virol 2001; 75: 6209-6211
-
(2001)
J Virol
, vol.75
, pp. 6209-6211
-
-
Polyak, S.J.1
Khabar, K.S.2
Rezeiq, M.3
Gretch, D.R.4
-
94
-
-
33746840523
-
Relationships between hepatitis C virus replication and CXCL-8 production in vitro
-
Koo BC, McPoland P, Wagoner JP, Kane OJ, Lohmann V, Polyak SJ. Relationships between hepatitis C virus replication and CXCL-8 production in vitro. J Virol 2006; 80: 7885-7893
-
(2006)
J Virol
, vol.80
, pp. 7885-7893
-
-
Koo, B.C.1
McPoland, P.2
Wagoner, J.P.3
Kane, O.J.4
Lohmann, V.5
Polyak, S.J.6
-
95
-
-
33845802039
-
Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection
-
Wagoner J, Austin M, Green J, Imaizumi T, Casola A, Brasier A, Khabar KS, Wakita T, Gale M Jr, Polyak SJ. Regulation of CXCL-8 (interleukin-8) induction by double-stranded RNA signaling pathways during hepatitis C virus infection. J Virol 2007; 81: 309-318
-
(2007)
J Virol
, vol.81
, pp. 309-318
-
-
Wagoner, J.1
Austin, M.2
Green, J.3
Imaizumi, T.4
Casola, A.5
Brasier, A.6
Khabar, K.S.7
Wakita, T.8
Gale Jr, M.9
Polyak, S.J.10
-
96
-
-
1842832228
-
Hepatitis C virus NS5A protein interacts with 2′,5′-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner
-
Taguchi T, Nagano-Fujii M, Akutsu M, Kadoya H, Ohgimoto S, Ishido S, Hotta H. Hepatitis C virus NS5A protein interacts with 2′,5′-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner. J Gen Virol 2004; 85: 959-969
-
(2004)
J Gen Virol
, vol.85
, pp. 959-969
-
-
Taguchi, T.1
Nagano-Fujii, M.2
Akutsu, M.3
Kadoya, H.4
Ohgimoto, S.5
Ishido, S.6
Hotta, H.7
-
97
-
-
0036233219
-
Activation and evasion of the antiviral 2′-5′, oligoadenylate synthetase/ribonuclease L pathway by hepatitis C virus mRNA
-
Han JQ, Barton DJ. Activation and evasion of the antiviral 2′-5′, oligoadenylate synthetase/ribonuclease L pathway by hepatitis C virus mRNA. RNA 2002; 8: 512-525
-
(2002)
RNA
, vol.8
, pp. 512-525
-
-
Han, J.Q.1
Barton, D.J.2
-
98
-
-
0038719944
-
Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNA
-
Vyas J, Elia A, Clemens MJ. Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNA. RNA 2003; 9: 858-870
-
(2003)
RNA
, vol.9
, pp. 858-870
-
-
Vyas, J.1
Elia, A.2
Clemens, M.J.3
-
99
-
-
0033516497
-
-
Taylor DR, Shi ST, Romano PR, Barber GN, Lai MM. Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein. Science 1999; 285: 107-110
-
Taylor DR, Shi ST, Romano PR, Barber GN, Lai MM. Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein. Science 1999; 285: 107-110
-
-
-
-
100
-
-
2442477701
-
The nature of interferon-alpha resistance in hepatitis C virus infection
-
Pawlotsky JM. The nature of interferon-alpha resistance in hepatitis C virus infection. Curr Opin Infect Dis 2003; 16: 587-592
-
(2003)
Curr Opin Infect Dis
, vol.16
, pp. 587-592
-
-
Pawlotsky, J.M.1
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