-
1
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou, L., A. C. Holt, R. Medzhitov, and R. A. Flavell. 2001. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413:732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
2
-
-
0029618697
-
Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes
-
Au, W. C., P. A. Moore, W. Lowther, Y. T. Juang, and P. M. Pitha. 1995. Identification of a member of the interferon regulatory factor family that binds to the interferon-stimulated response element and activates expression of interferon-induced genes. Proc. Natl. Acad. Sci. USA 92:11657-11661.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11657-11661
-
-
Au, W.C.1
Moore, P.A.2
Lowther, W.3
Juang, Y.T.4
Pitha, P.M.5
-
3
-
-
0034665047
-
Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription
-
Bonnard, M., C. Mirtsos, S. Suzuki, K. Graham, J. Huang, M. Ng, A. Itie, A. Wakeham, A. Shahinian, W. J. Henzel, A. J. Elia, W. Shillinglaw, T. W. Mak, Z. Cao, and W. C. Yen. 2000. Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription. EMBO J. 19:4976-4985.
-
(2000)
EMBO J.
, vol.19
, pp. 4976-4985
-
-
Bonnard, M.1
Mirtsos, C.2
Suzuki, S.3
Graham, K.4
Huang, J.5
Ng, M.6
Itie, A.7
Wakeham, A.8
Shahinian, A.9
Henzel, W.J.10
Elia, A.J.11
Shillinglaw, W.12
Mak, T.W.13
Cao, Z.14
Yen, W.C.15
-
4
-
-
0033257795
-
JNK2 and IKKβ are required for activating the innate response to viral infection
-
Chu, W. M., D. Ostertag, Z. W. Li, L. Chang, Y. Chen, Y. Hu, B. Williams, J. Perrault, and M. Karin. 1999. JNK2 and IKKβ are required for activating the innate response to viral infection. Immunity 11:721-731.
-
(1999)
Immunity
, vol.11
, pp. 721-731
-
-
Chu, W.M.1
Ostertag, D.2
Li, Z.W.3
Chang, L.4
Chen, Y.5
Hu, Y.6
Williams, B.7
Perrault, J.8
Karin, M.9
-
5
-
-
0842304532
-
Innate cellular response to virus particle entry requires IRF3 but not virus replication
-
Collins, S. E., R. S. Noyce, and K. L. Mossman. 2004. Innate cellular response to virus particle entry requires IRF3 but not virus replication. J. Virol. 78:1706-1717.
-
(2004)
J. Virol.
, vol.78
, pp. 1706-1717
-
-
Collins, S.E.1
Noyce, R.S.2
Mossman, K.L.3
-
6
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold, S. S., T. Kaisho, H. Hemmi, S. Akira, and E. S. C. Reis. 2004. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303:1529-1531.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis, E.S.C.5
-
7
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle, S., S. Vaidya, R. O'Connell, H. Dadgostar, P. Dempsey, T. Wu, G. Rao, R. Sun, M. Haberland, R. Modlin, and G. Cheng. 2002. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 17:251-263.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
Rao, G.7
Sun, R.8
Haberland, M.9
Modlin, R.10
Cheng, G.11
-
8
-
-
0038393016
-
IKKε and TBK1 are essential components of the IRF3 signaling pathway
-
Fitzgerald, K. A., S. M. McWhirter, K. L. Faia, D. C. Rowe, E. Latz, D. T. Golenbock, A. J. Coyle, S. M. Liao, and T. Maniatis. 2003. IKKε and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4:491-496.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 491-496
-
-
Fitzgerald, K.A.1
McWhirter, S.M.2
Faia, K.L.3
Rowe, D.C.4
Latz, E.5
Golenbock, D.T.6
Coyle, A.J.7
Liao, S.M.8
Maniatis, T.9
-
9
-
-
0141959224
-
LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the Toll adapters TRAM and TRIF
-
Fitzgerald, K. A., D. C. Rowe, B. J. Barnes, D. R. Caffrey, A. Visintin, E. Latz, B. Monks, P. M. Pitha, and D. T. Golenbock. 2003. LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the Toll adapters TRAM and TRIF. J. Exp. Med. 198:1043-1055.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1043-1055
-
-
Fitzgerald, K.A.1
Rowe, D.C.2
Barnes, B.J.3
Caffrey, D.R.4
Visintin, A.5
Latz, E.6
Monks, B.7
Pitha, P.M.8
Golenbock, D.T.9
-
10
-
-
0343431521
-
Translational control of viral gene expression in eukaryotes
-
Gale, M., S. L. Tan, and M. G. Katze. 2000. Translational control of viral gene expression in eukaryotes. Microbiol. Mol. Biol. Rev. 64:239-280.
-
(2000)
Microbiol. Mol. Biol. Rev.
, vol.64
, pp. 239-280
-
-
Gale, M.1
Tan, S.L.2
Katze, M.G.3
-
11
-
-
0342656954
-
Regulation of RANTES chemokine gene expression requires cooperativity between NF-κB and IFN-regulatory factor transcription factors
-
Genin, P., M. Algarte, P. Roof, R. Lin, and J. Hiscott. 2000. Regulation of RANTES chemokine gene expression requires cooperativity between NF-κB and IFN-regulatory factor transcription factors. J. Immunol. 164:5352-5361.
-
(2000)
J. Immunol.
, vol.164
, pp. 5352-5361
-
-
Genin, P.1
Algarte, M.2
Roof, P.3
Lin, R.4
Hiscott, J.5
-
12
-
-
0036092049
-
Transcriptional profiling of interferon regulatory factor 3 target genes: Direct involvement in the regulation of interferon-stimulated genes
-
Grandvaux, N., M. J. Servant, B. tenOever, G. C. Sen, S. Balachandran, G. N. Barber, R. Lin, and J. Hiscott. 2002. Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes. J. Virol. 76:5532-5539.
-
(2002)
J. Virol.
, vol.76
, pp. 5532-5539
-
-
Grandvaux, N.1
Servant, M.J.2
TenOever, B.3
Sen, G.C.4
Balachandran, S.5
Barber, G.N.6
Lin, R.7
Hiscott, J.8
-
13
-
-
0036105482
-
The interferon antiviral response: From viral invasion to evasion
-
Grandvaux, N., B. R. tenOever, M. J. Servant, and J. Hiscott. 2002. The interferon antiviral response: from viral invasion to evasion. Curr. Opin. Infect. Dis. 15:259-267.
-
(2002)
Curr. Opin. Infect. Dis.
, vol.15
, pp. 259-267
-
-
Grandvaux, N.1
TenOever, B.R.2
Servant, M.J.3
Hiscott, J.4
-
14
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil, F., H. Hemmi, H. Hochrein, F. Ampenberger, C. Kirschning, S. Akira, G. Lipford, H. Waguer, and S. Bauer. 2004. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303:1526-1529.
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Waguer, H.8
Bauer, S.9
-
15
-
-
0034025957
-
The IRF-3 transcription factor mediates Sendai virus-induced apoptosis
-
Heylbroeck, C., S. Balachandran, M. Servant, C. DeLuca, G. Barber, R. Lin, and J. Hiscott. 2000. The IRF-3 transcription factor mediates Sendai virus-induced apoptosis. J. Virol. 74:3781-3792.
-
(2000)
J. Virol.
, vol.74
, pp. 3781-3792
-
-
Heylbroeck, C.1
Balachandran, S.2
Servant, M.3
DeLuca, C.4
Barber, G.5
Lin, R.6
Hiscott, J.7
-
16
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
-
Hoebe, K., X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, K. Crozat, S. Sovath, J. Han, and B. Beutler. 2003. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424:743-748.
-
(2003)
Nature
, vol.424
, pp. 743-748
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
Crozat, K.11
Sovath, S.12
Han, J.13
Beutler, B.14
-
17
-
-
0037066314
-
Kinetic mechanisms of IκB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer
-
Huynh, Q. K., N. Kishore, S. Mathialagan, A. M. Donnelly, and C. S. Tripp. 2002. Kinetic mechanisms of IκB-related kinases (IKK) inducible IKK and TBK-1 differ from IKK-1/IKK-2 heterodimer. J. Biol. Chem. 277:12550-12558.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12550-12558
-
-
Huynh, Q.K.1
Kishore, N.2
Mathialagan, S.3
Donnelly, A.M.4
Tripp, C.S.5
-
18
-
-
0033970937
-
2-terminal kinase by double-stranded RNA and encephalomyocarditis virus: Involvement of RNase L, protein kinase R, and alternative pathways
-
2-terminal kinase by double-stranded RNA and encephalomyocarditis virus: involvement of RNase L, protein kinase R, and alternative pathways. Mol. Cell. Biol. 20:617-627.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 617-627
-
-
Iordanov, M.S.1
Paranjape, J.M.2
Zhou, A.3
Wong, J.4
Williams, B.R.5
Meurs, E.F.6
Silverman, R.H.7
Magun, B.E.8
-
19
-
-
0032544059
-
Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3
-
Juang, Y., W. Lowther, M. Kellum, W. C. Au, R. Lin, J. Hiscott, and P. M. Pitha. 1998. Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3. Proc. Natl. Acad. Sci. USA 95: 9837-9842.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9837-9842
-
-
Juang, Y.1
Lowther, W.2
Kellum, M.3
Au, W.C.4
Lin, R.5
Hiscott, J.6
Pitha, P.M.7
-
20
-
-
0037134530
-
IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: Comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2
-
Kishore, N., Q. K. Huynh, S. Mathialagan, T. Hall, S. Rouw, D. Creely, G. Lange, J. Caroll, B. Reitz, A. Donnelly, H. Boddupalli, R. G. Combs, K. Kretzmer, and C. S. Tripp. 2002. IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2. J. Biol. Chem. 277:13840-13847.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13840-13847
-
-
Kishore, N.1
Huynh, Q.K.2
Mathialagan, S.3
Hall, T.4
Rouw, S.5
Creely, D.6
Lange, G.7
Caroll, J.8
Reitz, B.9
Donnelly, A.10
Boddupalli, H.11
Combs, R.G.12
Kretzmer, K.13
Tripp, C.S.14
-
21
-
-
0038374178
-
IKKi/IKKε plays a key role in integrating signals induced by pro-inflammatory stimuli
-
Kravchenko, V. V., J. C. Mathison, K. Schwamborn, F. Mercurio, and R. J. Ulevitch. 2003. IKKi/IKKε plays a key role in integrating signals induced by pro-inflammatory stimuli. J. Biol. Chem. 278:26612-26619.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26612-26619
-
-
Kravchenko, V.V.1
Mathison, J.C.2
Schwamborn, K.3
Mercurio, F.4
Ulevitch, R.J.5
-
22
-
-
0033842515
-
Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7
-
Lin, R., P. Genin, Y. Mamane, and J. Hiscott. 2000. Selective DNA binding and association with the CREB binding protein coactivator contribute to differential activation of alpha/beta interferon genes by interferon regulatory factors 3 and 7. Mol. Cell. Biol. 20:6342-6353.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6342-6353
-
-
Lin, R.1
Genin, P.2
Mamane, Y.3
Hiscott, J.4
-
23
-
-
0032926882
-
Essential role of IRF-3 in direct activation of RANTES gene transcription
-
Lin, R., C. Heylbroeck, P. Genin, P. Pitha, and J. Hiscott. 1999. Essential role of IRF-3 in direct activation of RANTES gene transcription. Mol. Cell. Biol. 19:959-966.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 959-966
-
-
Lin, R.1
Heylbroeck, C.2
Genin, P.3
Pitha, P.4
Hiscott, J.5
-
24
-
-
0031893220
-
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation
-
Lin, R., C. Heylbroeck, P. M. Pitha, and J. Hiscott. 1998. Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation. Mol. Cell. Biol. 18:2986-2996.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2986-2996
-
-
Lin, R.1
Heylbroeck, C.2
Pitha, P.M.3
Hiscott, J.4
-
25
-
-
0034602156
-
Multiple regulatory domains control IRF-7 activity in response to virus infection
-
Lin, R., Y. Mamane, and J. Hiscott. 2000. Multiple regulatory domains control IRF-7 activity in response to virus infection. J. Biol. Chem. 275: 34320-34327.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34320-34327
-
-
Lin, R.1
Mamane, Y.2
Hiscott, J.3
-
26
-
-
0032915860
-
Structural and functional analysis of interferon regulatory factor 3: Localization of the transactivation and autoinhibitory domains
-
Lin, R., Y. Mamane, and J. Hiscott. 1999. Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains. Mol. Cell. Biol. 19:2465-2474.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2465-2474
-
-
Lin, R.1
Mamane, Y.2
Hiscott, J.3
-
27
-
-
0032844470
-
Cloning and functional analysis of the human IRF-3 promoter
-
Lowther, W. J., P. A. Moore, K. C. Carter, and P. M. Pitha. 1999. Cloning and functional analysis of the human IRF-3 promoter. DNA Cell Biol. 18:685-692.
-
(1999)
DNA Cell Biol.
, vol.18
, pp. 685-692
-
-
Lowther, W.J.1
Moore, P.A.2
Carter, K.C.3
Pitha, P.M.4
-
28
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Lund, J. M., L. Alexopoulou, A. Sato, M. Karow, N. C. Adams, N. W. Gale, A. Iwasaki, and R. A. Flavell. 2004. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc. Natl. Acad. Sci. USA 101:5598-5603.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5598-5603
-
-
Lund, J.M.1
Alexopoulou, L.2
Sato, A.3
Karow, M.4
Adams, N.C.5
Gale, N.W.6
Iwasaki, A.7
Flavell, R.A.8
-
29
-
-
0032538891
-
Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
-
Marie, I., J. E. Durbin, and D. E. Levy. 1998. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J. 17:6660-6669.
-
(1998)
EMBO J.
, vol.17
, pp. 6660-6669
-
-
Marie, I.1
Durbin, J.E.2
Levy, D.E.3
-
30
-
-
0345827590
-
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
-
McWhirter, S. M., K. A. Fitzgerald, J. Rosains, D. C. Rowe, D. T. Golenbock, and T. Maniatis. 2004. IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts. Proc. Natl. Acad. Sci. USA 101:233-238.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 233-238
-
-
McWhirter, S.M.1
Fitzgerald, K.A.2
Rosains, J.3
Rowe, D.C.4
Golenbock, D.T.5
Maniatis, T.6
-
31
-
-
0037066502
-
Decoding the patterns of self and nonself by the innate immune system
-
Medzhitov, R., and C. A. Janeway, Jr. 2002. Decoding the patterns of self and nonself by the innate immune system. Science 296:298-300.
-
(2002)
Science
, vol.296
, pp. 298-300
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
32
-
-
1642297150
-
Identification of Ser 386 of interferon regulatory factor 3 as critical targets for inducible phosphorylation that determines activation
-
Mori, M., M. Yoneyama, T. Ito, K. Takahashi, F. Inagaki, and T. Fujita. 2004. Identification of Ser 386 of interferon regulatory factor 3 as critical targets for inducible phosphorylation that determines activation. J. Biol. Chem. 279:9698-9702.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9698-9702
-
-
Mori, M.1
Yoneyama, M.2
Ito, T.3
Takahashi, K.4
Inagaki, F.5
Fujita, T.6
-
33
-
-
0025734250
-
Assembly and transcription of synthetic vesicular stomatitis virus nucleocapsids
-
Mover, S. A., S. Smallwood-Kentro, A. Haddad, and L. Prevec. 1991. Assembly and transcription of synthetic vesicular stomatitis virus nucleocapsids. J. Virol. 65:2170-2178.
-
(1991)
J. Virol.
, vol.65
, pp. 2170-2178
-
-
Mover, S.A.1
Smallwood-Kentro, S.2
Haddad, A.3
Prevec, L.4
-
34
-
-
0037320451
-
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
-
Oshiumi, H., M. Matsumoto, K. Funami, T. Akazawa, and T. Seya. 2003. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat. Immunol. 4:161-167.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 161-167
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
36
-
-
0033623848
-
IKKε is part of a novel PMA-inducible IκB kinase complex
-
Peters, R. T., S. M. Liao, and T. Maniatis. 2000. IKKε is part of a novel PMA-inducible IκB kinase complex. Mol. Cell 5:513-522.
-
(2000)
Mol. Cell
, vol.5
, pp. 513-522
-
-
Peters, R.T.1
Liao, S.M.2
Maniatis, T.3
-
37
-
-
0242574745
-
Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation
-
Qin, B. Y., C. Liu, S. S. Lam, H. Srinath, R. Delston, J. J. Correia, R. Derynck, and K. Lin. 2003. Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation. Nat. Struct. Biol. 10: 913-921.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 913-921
-
-
Qin, B.Y.1
Liu, C.2
Lam, S.S.3
Srinath, H.4
Delston, R.5
Correia, J.J.6
Derynck, R.7
Lin, K.8
-
38
-
-
0042572276
-
Viruses and Toll-like receptors
-
Rassa, J. C., and S. R. Ross. 2003. Viruses and Toll-like receptors. Microbes Infect. 5:961-968.
-
(2003)
Microbes Infect.
, vol.5
, pp. 961-968
-
-
Rassa, J.C.1
Ross, S.R.2
-
39
-
-
0041589513
-
Toll-like receptors in health and disease: Complex questions remain
-
Sabroe, I., R. C. Read, M. K. Whyte, D. H. Dockrell, S. N. Vogel, and S. K. Dower. 2003. Toll-like receptors in health and disease: complex questions remain. J. Immunol. 171:1630-1635.
-
(2003)
J. Immunol.
, vol.171
, pp. 1630-1635
-
-
Sabroe, I.1
Read, R.C.2
Whyte, M.K.3
Dockrell, D.H.4
Vogel, S.N.5
Dower, S.K.6
-
40
-
-
0034767753
-
Antiviral actions of interferons
-
Samuel, C. E. 2001. Antiviral actions of interferons. Clin. Microbiol. Rev. 14:778-809.
-
(2001)
Clin. Microbiol. Rev.
, vol.14
, pp. 778-809
-
-
Samuel, C.E.1
-
41
-
-
0032434924
-
Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7
-
Sato, M., N. Hata, M. Asagiri, T. Nakaya, T. Taniguchi, and N. Tanaka. 1998. Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7. FEBS Left. 441:106-110.
-
(1998)
FEBS Left.
, vol.441
, pp. 106-110
-
-
Sato, M.1
Hata, N.2
Asagiri, M.3
Nakaya, T.4
Taniguchi, T.5
Tanaka, N.6
-
42
-
-
0033680737
-
Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction
-
Sato, M., H. Suemori, N. Hata, M. Asagiri, K. Ogasawara, K. Nakao, T. Nakaya, M. Katsuki, S. Noguchi, N. Tanaka, and T. Taniguchi. 2000. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 13:539-548.
-
(2000)
Immunity
, vol.13
, pp. 539-548
-
-
Sato, M.1
Suemori, H.2
Hata, N.3
Asagiri, M.4
Ogasawara, K.5
Nakao, K.6
Nakaya, T.7
Katsuki, M.8
Noguchi, S.9
Tanaka, N.10
Taniguchi, T.11
-
43
-
-
0032549658
-
Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-beta gene
-
Sato, M., N. Tanaka, N. Hata, E. Oda, and T. Taniguchi. 1998. Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-beta gene. FEBS Lett. 425:112-116.
-
(1998)
FEBS Lett.
, vol.425
, pp. 112-116
-
-
Sato, M.1
Tanaka, N.2
Hata, N.3
Oda, E.4
Taniguchi, T.5
-
44
-
-
0141923690
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIP) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κB and IFN-regulatory factor-3, in the Toll-like receptor signaling
-
Sato, S., M. Sugiyama, M. Yamamoto, Y. Watanabe, T. Kawai, K. Takeda, and S. Akira. 2003. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIP) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-κB and IFN-regulatory factor-3, in the Toll-like receptor signaling. J. Immunol. 171:4304-4310.
-
(2003)
J. Immunol.
, vol.171
, pp. 4304-4310
-
-
Sato, S.1
Sugiyama, M.2
Yamamoto, M.3
Watanabe, Y.4
Kawai, T.5
Takeda, K.6
Akira, S.7
-
45
-
-
0034769960
-
Viruses and interferons
-
Sen, G. C. 2001. Viruses and interferons. Annu. Rev. Microbiol. 55:255-281.
-
(2001)
Annu. Rev. Microbiol.
, vol.55
, pp. 255-281
-
-
Sen, G.C.1
-
46
-
-
0036710523
-
Multiple signaling pathways leading to the activation of interferon regulatory factor 3
-
Servant, M. J., N. Grandvaux, and J. Hiscott. 2002. Multiple signaling pathways leading to the activation of interferon regulatory factor 3. Biochem. Pharmacol. 64:985-992.
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 985-992
-
-
Servant, M.J.1
Grandvaux, N.2
Hiscott, J.3
-
47
-
-
0038660668
-
Identification of the minimal phosphoacceptor site required for in vivo activation of IRF-3 in response to virus and dsRNA
-
Servant, M. J., N. Grandvaux, B. R. TenOever, D. Duguay, R. Lin, and J. Hiscott. 2003. Identification of the minimal phosphoacceptor site required for in vivo activation of IRF-3 in response to virus and dsRNA. J. Biol. Chem. 278:9441-9447.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9441-9447
-
-
Servant, M.J.1
Grandvaux, N.2
TenOever, B.R.3
Duguay, D.4
Lin, R.5
Hiscott, J.6
-
48
-
-
0035808446
-
Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3
-
Servant, M. J., B. ten Oever, C. LePage, L. Conti, S. Gessani, I. Julkunen, R. Lin, and J. Hiscott. 2001. Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3. J. Biol. Chem. 276:355-363.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 355-363
-
-
Servant, M.J.1
Ten Oever, B.2
LePage, C.3
Conti, L.4
Gessani, S.5
Julkunen, I.6
Lin, R.7
Hiscott, J.8
-
49
-
-
0038363463
-
Triggering the interferon antiviral response through an IKK· related pathway
-
Sharma, S., B. R. tenOever, N. Grandvaux, G. P. Zhou, R. Lin, and J. Hiscott. 2003. Triggering the interferon antiviral response through an IKK· related pathway. Science 300:1148-1151.
-
(2003)
Science
, vol.300
, pp. 1148-1151
-
-
Sharma, S.1
TenOever, B.R.2
Grandvaux, N.3
Zhou, G.P.4
Lin, R.5
Hiscott, J.6
-
50
-
-
0032808084
-
IKK-i, a novel lipopolysaccharide-inducible kinase that is related ,to IκB kinases
-
Shimada, T., T. Kawai, K. Takeda, M. Matsumoto, J. Inoue, Y. Tatsumi, A. Kanamaru, and S. Akira. 1999. IKK-i, a novel lipopolysaccharide-inducible kinase that is related ,to IκB kinases. Int. Immunol. 11:1357-1362.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1357-1362
-
-
Shimada, T.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Inoue, J.5
Tatsumi, Y.6
Kanamaru, A.7
Akira, S.8
-
51
-
-
0035937802
-
IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or IκB kinase but is blocked by vaccinia virus E3L protein
-
Smith, E. J., I. Marie, A. Prakash, A. Garcia-Sastre, and D. E. Levy. 2001. IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or IκB kinase but is blocked by vaccinia virus E3L protein. J. Biol. Chem. 276:8951-8957.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8951-8957
-
-
Smith, E.J.1
Marie, I.2
Prakash, A.3
Garcia-Sastre, A.4
Levy, D.E.5
-
52
-
-
0242658895
-
X-ray crystal structure of IRF-3 and its functional implications
-
Takahasi, K., N. N. Suzuki, M. Horiuchi, M. Mori, W. Suhara, Y. Okabe, Y. Fukuhara, H. Terasawa, S. Akira, T. Fujita, and F. Inagaki. 2003. X-ray crystal structure of IRF-3 and its functional implications. Nat. Struct. Biol. 10:922-927.
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 922-927
-
-
Takahasi, K.1
Suzuki, N.N.2
Horiuchi, M.3
Mori, M.4
Suhara, W.5
Okabe, Y.6
Fukuhara, Y.7
Terasawa, H.8
Akira, S.9
Fujita, T.10
Inagaki, F.11
-
54
-
-
0036199090
-
Recognition of the measles viral nucleocapsid as a mechanism of IRF-3 activation
-
tenOever, B. R., M. J. Servant, N. Grandvaux, R. Lin, and J. Hiscott. 2002. Recognition of the measles viral nucleocapsid as a mechanism of IRF-3 activation. J. Virol. 76:3659-3669.
-
(2002)
J. Virol.
, vol.76
, pp. 3659-3669
-
-
TenOever, B.R.1
Servant, M.J.2
Grandvaux, N.3
Lin, R.4
Hiscott, J.5
-
55
-
-
0035128587
-
Apoptosis is promoted by the dsRNA-activated factor (DRAF1) during viral infection independent of the action of interferon or p53
-
Weaver, B. K., O. Ando, K. P. Kumar, and N. C. Reich. 2001. Apoptosis is promoted by the dsRNA-activated factor (DRAF1) during viral infection independent of the action of interferon or p53. FASEB J. 15:501-515.
-
(2001)
FASEB J.
, vol.15
, pp. 501-515
-
-
Weaver, B.K.1
Ando, O.2
Kumar, K.P.3
Reich, N.C.4
-
56
-
-
0043176281
-
Role of adaptor TRIP in the MyD88-independent Toll-like receptor signaling pathway
-
Yamamoto, M., S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Saujo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira. 2003. Role of adaptor TRIP in the MyD88-independent Toll-like receptor signaling pathway. Science 301:640-643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Saujo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
57
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
-
Yamamoto, M., S. Sato, K. Mori, K. Hoshino, O. Takeuchi, K. Takeda, and S. Akira. 2002. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J. Immunol. 169:6668-6672.
-
(2002)
J. Immunol.
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
58
-
-
0032481352
-
Direct triggering of the type I interferon system by virus infection: Activation of a transcription factor complex containing IRF-3 and CBP/p300
-
Yoneyama, M., W. Suhara, Y. Fukuhara, M. Fukada, E. Nishida, and T. Fujita. 1998. Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J. 17:1087-1095.
-
(1998)
EMBO J.
, vol.17
, pp. 1087-1095
-
-
Yoneyama, M.1
Suhara, W.2
Fukuhara, Y.3
Fukada, M.4
Nishida, E.5
Fujita, T.6
|