IRF3 and IRF7 Phosphorylation in Virus-infected Cells Does Not Require Double-stranded RNA-dependent Protein Kinase R or IκB Kinase but is Blocked by Vaccinia Virus E3L Protein

Journal of Biological Chemistry

Volumn 276, Issue 12, 2001, Pages 8951-8957

  Smith, Eric J ^a   Marié, Isabelle ^a,c   Prakash, Arun ^a   García Sastre, Adolfo ^b   Levy, David E ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; ENZYME KINETICS; GENETIC ENGINEERING; MUTAGENESIS; PROTEINS; RNA; VIRUSES;

PHOSPHORYLATION; PROTEIN PRODUCTIONS;

BIOCHEMISTRY;

CELL PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DOUBLE STRANDED RNA; GAMMA INTERFERON; I KAPPA B KINASE; MUTANT PROTEIN; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN INHIBITOR; PROTEIN KINASE; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE R; RNA BINDING PROTEIN; STAUROSPORINE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IRF3; TRANSCRIPTION FACTOR IRF7; UNCLASSIFIED DRUG; VIRUS PROTEIN; ALPHA INTERFERON; CHUK PROTEIN, MOUSE; DNA BINDING PROTEIN; E3L PROTEIN, VACCINIA VIRUS; ENZYME INHIBITOR; IKBKB PROTEIN, MOUSE; IKBKE PROTEIN, MOUSE; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; IRF3 PROTEIN, MOUSE; IRF7 PROTEIN, MOUSE; PRIMER DNA; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; GENE ACTIVATION; GENE EXPRESSION; GENE INACTIVATION; GENE INDUCTION; HUMAN; HUMAN CELL; KINETICS; MOLECULAR GENETICS; MOUSE; NEWCASTLE DISEASE PARAMYXOVIRUS; NONHUMAN; PARAMETER; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; VACCINIA VIRUS; VIRUS INFECTION; VIRUS PARTICLE; ANIMAL; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS;

ANIMALIA; DNA VIRUSES; NEWCASTLE DISEASE VIRUS; PARAMYXOVIRIDAE; RNA VIRUSES; VACCINIA VIRUS;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; DNA-BINDING PROTEINS; EIF-2 KINASE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, VIRAL; I-KAPPA B KINASE; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS; VIRAL PROTEINS;

EID: 0035937802     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008717200     Document Type: Article

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