Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents

Current Drug Targets

Volumn 8, Issue 3, 2007, Pages 399-411

  Oliveira, J S ^a   Vasconcelos, I B ^a   Moreira, I S ^b   Santos, Diogenes S ^a   Basso, Luiz A ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

Drugs; Enoyl reductase; InhA; Isoniazid; Mycolic acids; Myobacteria; Tuberculosis

Indexed keywords

AMIKACIN; AMINOSALICYLIC ACID; AMODIAQUINE; ANTIMALARIAL AGENT; ARTEMISININ; ARTESUNATE; CHLOROQUINE; CYCLOSERINE; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); ETHAMBUTOL; ETHIONAMIDE; FANSIDAR; HYDROXY FATTY ACID; ISONIAZID; ISONIAZID DERIVATIVE; KANAMYCIN; MEFLOQUINE; MYCOLIC ACID; OXIDOREDUCTASE; PYRAZINAMIDE; PYRIMETHAMINE; QUININE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; STREPTOMYCIN; SULFADOXINE; THIOESTER; TRICLOSAN; TUBERCULOSTATIC AGENT; UNINDEXED DRUG;

ANTIBIOTIC RESISTANCE; CHEMICAL ANALYSIS; COMBINATION CHEMOTHERAPY; COST OF ILLNESS; DRUG MECHANISM; DRUG METABOLISM; DRUG STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; FATTY ACID SYNTHESIS; GENETIC ANALYSIS; HUMAN; MALARIA; MOLECULAR WEIGHT; MORBIDITY; MORTALITY; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PLASMODIUM FALCIPARUM; PRESCRIPTION; PRODUCT DEVELOPMENT; REVIEW; STRUCTURAL GENE; TUBERCULOSIS; UNSPECIFIED SIDE EFFECT;

ANIMALS; ANTIMALARIALS; ANTITUBERCULAR AGENTS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); ENZYME INHIBITORS; HUMANS;

EID: 33847779109     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945007780058942     Document Type: Review

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