Inhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachlorophene

Journal of Biological Chemistry

Volumn 275, Issue 7, 2000, Pages 4654-4659

  Heath, Richard J ^a   Li, Jing ^b   Roland, Gregory E ^b   Rock, Charles O ^a,c  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEIN; FATTY ACID SYNTHASE; HEXACHLOROPHENE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRICLOSAN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM MUTANT; CROSS RESISTANCE; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ESCHERICHIA COLI; MISSENSE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; BASE SEQUENCE; CLONING, MOLECULAR; DNA PRIMERS; ENOYL-(ACYL-CARRIER PROTEIN) REDUCTASE (NADPH, B-SPECIFIC); ENZYME INHIBITORS; ESCHERICHIA COLI; HEXACHLOROPHENE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OXIDOREDUCTASES; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS; TRICLOSAN;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 0034681329     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.7.4654     Document Type: Article

References (32)

1. Cronan, J. E., Jr., and Rock, C. O. (1996) in Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology (Neidhardt, F. C., Curtis, R., Gross, C. A., Ingraham, J. L., Lin, E. C. C., Low, K. B., Magasanik, B., Reznikoff, W., Riley, M., Schaechter, M., and Umbarger, H. E., (eds) pp. 612-636, American Society for Microbiology, Washington, D. C.
2. Rock, C. O., and Cronan, J. E., Jr. (1996) Biochim. Biophys. Acta 1302, 1-16
3. Heath, R. J., and Rock, C. O. (1995) J. Biol. Chem. 270, 26538-26542
4. Heath, R. J., and Rock, C. O. (1996) J. Biol. Chem. 271, 1833-1836
5. Baldock, C., Rafferty, J. B., Sedelnikova, S. E., Baker, P. J., Stuitje, A. R., Slabas, A. R., Hawkes, T. R., and Rice, D. W. (1996) Science 274, 2107-2110
6. Baldock, C., de Boer, G.-J., Rafferty, J. B., Stuitje, A. R., and Rice, D. W. (1998) Biochem. Pharmacol. 55, 1541-1549
7. Banerjee, A., Dubnau, E., Quémard, A., Balasubramanian, V., Um, K. S., Wilson. T., Collins, D., de Lisle, G., and Jacobs, W. R., Jr. (1994) Science 263, 227-230
8. Rozwarski, D., Grant, G., Barton, D., Jacobs, W., and Sacchettini, J. C. (1998) Science 279, 98-102
9. McMurray, L. M., Oethinger, M., and Levy, S. (1998) Nature 394, 531-532
10. Heath, R. J., Yu, Y.-T., Shapiro, M. A., Olson, E., and Rock, C. O. (1998) J. Biol. Chem. 273, 30316-30321
11. McMurry, L. M., McDermott, P. F., and Levy, S. B. (1999) Anlimicrob. Agents Chemother. 43, 711-713
12. Heath, R. J., Rubin, J. R., Holland, D. R., Zhang, E., Snow, M. E., and Rock, C. O. (1999) J. Biol. Chem. 274, 11110-11114
13. Levy, C. W., Roujeinikova, A., Sedelnikova, S., Baker, P. J., Stuitje, A. R., Slabas, A. R., Rice, D. W., and Rafferty, J. B. (1999) Nature 398, 383-384
14. Stewart, M. J., Parikh, S., Xiao, G., Tonge, P. J., and Kisker, C. (1999) J. Mol. Biol. 290, 859-865
15. Bhargava, H. N., and Leonard, P. A. (1996) Am. J. Infect. Control 24, 209-218
16. Regös, J., Zak, O., Solf, R., Vischer, W. A., and Weirich, E. G. (1979) Dermatologica 158, 72-79
17. Vischer, W. A., and Regös, J. (1974) Zentbl. Bakteriol. Mikrobiol. Hyg. 1 Abt Orig. A 226, 376-389
18. Regös, J., and Hitz, H. R. (1974) Zentbl. Bakteriol. Mikrobiol. Hyg. 1 Abt Orig. A 226, 390-401
19. Jungermann, E. (1968) J. Am. Oil Chem. Soc. 45, 345-350
20. Molnar, N. M. (1969) J. Soc. Cosmet. Chem. 20, 103-108
21. Gump, W. S., and Walter, G. R. (1968) in The bis-Phenols (Lawrence, C. A., and Block, S. S., eds) pp. 257-277, Lea and Febiger, Philadelphia
22. Corner, T. R., Joswick H. L., Silvernale, J. N., and Gerhardt, P. (1971) J. Bacteriol. 108, 501-507
23. Joswick, H. L., Corner, T. R., Silvernale, J. N., and Gerhardt, P. (1971) J. Bacteriol. 108, 492-500
24. Silvernale, J. N., Joswick H. L., Corner, T. R., and Gerhardt, P. (1971) J. Bacteriol. 108, 482-491
25. Novick, R. P. (1990) Molecular Biology of Staphylococci, VCH Publishers, New York
26. Pitcher, D. G., Saunder, N. A., and Owen, R. J. (1989) Lett. Appl. Microbiol. 8, 151-156
27. Jones, C. L., and Kahn, S. A. (1986) J. Bacteriol. 166, 29-33
28. Morrison, J. F., and Walsh, C. T. (1988) Adv. Enzymol. 61, 201-301
29. Weeks, G., and Wakil, S. J. (1968) J. Biol. Chem. 243, 1180-1189
30. Bergler, H., Wallner, P., Ebeling, A., Leitinger, B., Fuchsbichler, S., Aschauer, H., Kollenz, G., Högenauer, G., and Turnowsky, F. (1994) J. Biol. Chem. 269, 5493-5496
31. Bergler, H., Fuchsbichler, S., Högenauer, G., and Turnowsky, F. (1996) Eur. J. Biochem. 242, 689-694
32. White, D. C., and Frerman, F. E. (1968) J. Bacteriol. 95, 2198-2209