Mechanism of triclosan inhibition of bacterial fatty acid synthesis

Journal of Biological Chemistry

Volumn 274, Issue 16, 1999, Pages 11110-11114

  Heath, Richard J ^a   Rubin, J Ronald ^b   Holland, Debra R ^b   Zhang, Erli ^b   Snow, Mark E ^b   Rock, Charles O ^a,c  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; TRICLOSAN;

ARTICLE; BINDING AFFINITY; DRUG RESISTANCE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; GENE EXPRESSION; GENE MUTATION; HYDROGEN BOND; HYDROPHOBICITY; MISSENSE MUTATION; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); FATTY ACIDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MUTATION, MISSENSE; NAD; OXIDOREDUCTASES; PROTEIN BINDING; TRICLOSAN;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0033574422     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.16.11110     Document Type: Article

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