Location of functional groups in mycobacterial meromycolate chains; the recognition of new structural principles in mycolic acids

Microbiology

Volumn 148, Issue 6, 2002, Pages 1881-1902

  Watanabe, Motoko ^a   Aoyagi, Yutaka ^a   Mitome, Hidemichi ^a   Fujita, Tsuyoshi ^a   Naoki, Hideo ^a   Ridell, Malin ^a   Minnikin, David E ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

CID mass spectrometry; Meromycolic acids; Spacing between functional groups

Indexed keywords

CYCLOPROPANE; FUNCTIONAL GROUP; MYCOLIC ACID; OXIDE; SILVER; HYDROGEN;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BOND; CHEMICAL STRUCTURE; CHROMATOGRAPHY; CONTROLLED STUDY; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; FATTY ACID ANALYSIS; MYCOBACTERIUM BOVIS; MYCOBACTERIUM MICROTI; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PYROLYSIS; SILVER STAINING; CHEMISTRY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; MYCOBACTERIUM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOGENICITY;

ACTINOBACTERIA (CLASS); MYCOBACTERIUM; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM MICROTI; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

HYDROGEN; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; MYCOLIC ACIDS;

EID: 0035987344     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-148-6-1881     Document Type: Article

References (35)

1. Charge-remote fragmentations for structural determination of lipids
2. Mycolic acids: Structure, biosynthesis and physiological functions
3. The envelope of mycobacteria
4. Applications and mechanism of charge-remote fragmentation
5. Characterization of the neutral products formed upon the charge-remote fragmentation of fatty acid ions
6. Collision activation of a series of homoconjugated octadecadienoic acids with fast atom bombardment and tandem mass spectrometry
7. Structures of the two homologous series of dialkene mycolic acids from Mycobacterium smegmatis
8. Molecular mechanics of the mycobacterial cell wall: From horizontal layers to vertical scaffolds
9. The outer parts of the mycobacterial envelope as permeability barriers
10. Mycobacterium bovis BCG genes involved in the biosynthesis of cyclopropyl keto- and hydroxy-mycolic acids
11. Oxygenated mycolic acids are necessary for virulence of Mycobacterium tuberculosis in mice
12. Structure of mycobacterial bis-cyclopropane mycolates by mass spectometry
13. The biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis
14. The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase
15. Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope
16. Gas-phase ion decompositions occurring remote to charge site
17. Sur la structure d'un nouveau type d'acides mycoliques de Mycobacterium smegmatis
18. Some problems concerning biological C-alkylation reaction and phytosterol biosynthesis
19. A mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids accumulates meromycolates
20. Mycolic acid structure determines the fluidity of the mycobacterial cell wall
21. Locations of the mycoloyl ester substituents in the cell walls of mycobacteria
22. The methoxymycolic and ketomycolic acids from human tubercle bacilli
23. The mycolic acids from human and avian bacilli
24. Re-evaluation of envelope profiles and cytoplasmic ultrastructure of mycobacteria processed by conventional embedding and freeze-substitution protocols
25. Preservation of surface lipids and determination of ultrastructure of Mycobacterium kansasii by freeze-substitution
26. Characterization of the purified components of a new homologous series of alpha-mycolic acids from Mycobacterium tuberculosis H37Ra
27. Structure determination of mycolic acids by using charge-remote fragmentation
28. The specificity of methyl transferases involved in trans mycolic acid biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis
29. History of H37 strain of human tubercle bacillus
30. Separation of homologous series of mycolic acids from Mycobacterium tuberculosis H37Ra by high performance liquid chromatography
31. Fast atom bombardment and tandem mass spectrometry for determining structural modification of fatty acids
32. Cell wall structure of a mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids
33. Separation and characterization of individual mycolic acids in representative mycobacteria
34. Identification of a gene involved in the biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis
35. The effect of oxygenated mycolic acid composition on cell wall function and macrophage growth in Mycobacterium tuberculosis