Inhibiting activities of the secondary metabolites of Phlomis brunneogaleata against parasitic protozoa and plasmodial enoyl-ACP reductase, a crucial enzyme in fatty acid biosynthesis

Planta Medica

Volumn 70, Issue 8, 2004, Pages 711-717

  Kirmizibekmez, Hasan ^a   Çalis, Ihsan ^a   Perozzo, Remo ^b   Brun, Reto ^c   Dönmez, Ali A ^a   Linden, Anthony ^d   Rüedi, Peter ^d   Tasdemir, Deniz ^d  

^a HACETTEPE UNIVERSITY   (Turkey)

^b ETH ZURICH   (Switzerland)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Betonicine; Iridoid; Lamiaceae; Luteolin 7 O D glucopyranoside; Phlomis brunneogaleata; Plasmodium falciparum enoyl acyl carrier protein reductase (FabI); Pyrrolidinium derivative; Type II fatty acid synthase (FAS II)

Indexed keywords

2 CARBOXY 4 (4 COUMAROYLOXY) 1,1 DIMETHYLPYRROLIDINIUM; 3 O CAFFEOYLQUINIC ACID METHYL ESTER; 4 HYDROXYACETOPHENONE 4 O (6' O BETA DEXTRO APIOFURANOSYL) BETA DEXTRO GLUCOPYRANOSIDE; ACETOPHENONE DERIVATIVE; ACTEOSIDE; ANTIMALARIAL AGENT; BRUNNEOGALEATOSIDE; CAFFEIC ACID DERIVATIVE; CHLOROGENIC ACID; CHRYSOERIOL 7 O BETA DEXTRO GLUCOPYRANOSIDE; DACTYLIFERIC ACID; ECHINACOSIDE; ENOYL ACYL CARRIER PROTEIN REDUCTASE; FATTY ACID; FLAVONE DERIVATIVE; FORSYTHOSIDE B; GLUCOSE DERIVATIVE; INTEGRIFOLIOSIDE B; IPOLAMIID; IRIDOID; ISOACTEOSIDE; LIGNAN DERIVATIVE; LIRIODENDRIN; LUTEOLIN 7 O BETA DEXTRO GLUCOPYRANOSIDE; PHLOMIS BRUNNEOGALEATA EXTRACT; PLANT EXTRACT; PLANT GLYCOSIDE; PROTOZOAL PROTEIN; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; FRACTIONATION; IC 50; INFRARED RADIATION; MASS SPECTROMETRY; MEDICINAL PLANT; METABOLITE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHLOMIS; PHLOMIS BRUNNEOGALEATA; RAT; SPECTROSCOPY; ULTRAVIOLET SPECTROSCOPY; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTIMALARIALS; CELL LINE; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); HUMANS; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; MYOBLASTS; OXIDOREDUCTASES; PARASITIC SENSITIVITY TESTS; PHLOMIS; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; PLASMODIUM FALCIPARUM; RATS; TRYPANOSOMA;

ANIMALIA; LAMIACEAE; PHLOMIS; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 4444261960     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-827200     Document Type: Article

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