Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis

Journal of Biological Chemistry

Volumn 273, Issue 46, 1998, Pages 30316-30320

  Heath, Richard J ^a   Yu, Yuen Tsu ^b   Shapiro, Martin A ^b   Olson, Eric ^b   Rock, Charles O ^a,c  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYDIPHENYL ETHER DERIVATIVE; ANTIINFECTIVE AGENT; IMMUNOGLOBULIN F(AB) FRAGMENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BACTERIAL MEMBRANE; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; CATTLE; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); FATTY ACID SYNTHETASE COMPLEX; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; OXIDOREDUCTASES; PHENOLS; TRICLOSAN;

EID: 0032515066     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.46.30316     Document Type: Article

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